Jagadeesan Moorthy

@srmist.edu.in

Assistant Professor / Pharmacy Practice / Medical and Health Sciences
SRM College of Pharmacy, SRM IST

Jagadeesan Moorthy


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https://researchid.co/jagapharmd2013

RESEARCH, TEACHING, or OTHER INTERESTS

Drug Discovery, Pharmacology, Toxicology and Pharmaceutics
13

Scopus Publications

116

Scholar Citations

6

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • A comparison of the effectiveness of lacosamide and pregabalin in treating patients diagnosed with neuropathic pain: a randomized, controlled, open-label pilot trial
    R. Kalpana, W. S. Robert, Fatema Juzerehaji, Ramesh Venkatachalapathy, M. Jagadeesan
    Naunyn Schmiedeberg S Archives of Pharmacology, 2026
  • Safety and efficacy of LibidUp-PE supplement on premature ejaculation: A randomized, placebo-controlled double-blind, crossover study
    Jagadeesan M, Adhisaya A, T. Srinivasan, Alphienes Stanley Xavier, Pavithra Anandan, Rajappan Chandra Satish Kumar, Thangavel Mahalingam Vijayakumar
    Pharmaceutical Science Advances, 2024
    Premature ejaculation (PE) is the most common male sexual dysfunction. Selective serotonin reuptake inhibitors (SSRIs) are currently recommended for PE. However, the side effects of SSRIs, such as nausea, vomiting, and xerostomia, pose challenges to clinicians. Simultaneously, evidence indicates that psychological and behavioral treatments are often insufficient. LibidUp-PE is a nutraceutical designed to enhance sexual wellness and contains a combination of essential amino acids to boost stamina and vigor, addressing concerns like erectile dysfunction (ED). This study aimed to assess the safety and efficacy of LibidUp-PE in the treatment of PE. In this crossover, double-blind, placebo-controlled trial, 76 patients with PE were randomly divided into two groups. Group A received LibidUp-PE, whereas Group B received a placebo for 12 weeks. Following a 2-week wash-out period, the groups switched treatments for another 12 weeks. Intravaginal ejaculatory latency time (IELT) and post-ejaculatory refractory time (PERT) were measured as the primary outcomes to evaluate PE improvement. Plasma serotonin levels were measured as secondary parameters using enzyme-linked immunosorbent assay. The results showed that LibidUp-PE significantly improved the IELT score, increasing from 0.8 ± 0.2 min to 2.9 ± 1.1 min (p < 0.01). PERT scores also significantly decreased from 15.8 ± 1.7 min to 5.6 ± 0.6 min after 12 weeks of LibidUp-PE treatment. Plasma serotonin levels significant increased from 93.6 ± 7.8 ng/mL to 168.4 ± 12.8 ng/mL (p < 0.001) with LibidUp-PE treatment. In contrast, no significant improvements were observed in the placebo group. Notably, none of the participants withdrew their consent due to adverse reactions, which is indicative of the safety and tolerability of LibidUp-PE. In conclusion, 12-week treatment with LibidUp-PE demonstrated a beneficial effect in reducing PE symptoms, as reflected by improved IELT, reduced PERT, and increased plasma serotonin levels. Therefore, LibidUp-PE could be a promising solution for individuals with PE.
  • Evaluation of Malnutrition by Skinfold Thickness Measurement and SGA-DMS among Haemodialysis Patients: A Cross-Sectional Study
    M Jagadeesan, Subramanian Sreedhar, T M, Vijayakumar
    Journal of Medicinal and Chemical Sciences, 2023
    Protein-energy malnutrition occurs in a large portion of patients with chronic renal failure. It leads to the consequences of various factors like hormonal imbalance, reduced food intake caused by uremic toxicity, superimposed illnesses, infections, and protein and energy metabolism disturbances. Malnutrition could be acute or chronic in hemodialysis patients. One hundred fifty-two patients were involved in this cross-sectional study; we utilized SGA- DMS (Subjective Global Assessment- Dialysis Malnutrition Score). Percentage body fat through Skinfold Thickness Measurement was calculated using Durnin and Womersley equation. Pearson’s correlation coefficient was calculated to determine the correlation between the assessed parameters and the scores obtained from SGA-DMS. Student t-test was used to analyze the mean percentage of body fat observed between men and women. The values were considered statistically significant if the p-value was <0.05. On assessing the anthropometric parameters, the bicep skinfold thickness was positively correlated (p value=0.012) with the SGA- DMS tool, while all others were negatively correlated with the SGA- DMS. Percentage body fat results imply that patients have higher body fat levels, with males recording 31.34 ± 2.9 and women recording 37.35 ± 2.5, being statistically significant. Our study has not found significance in correlating SGA- DMS and factors like age, weight, etc. However, subjects observed have healthy nutritional status and mainly were over-weight. By employing other methods along with SGA-DMS, a better assessment of malnutrition could be made possible. In addition, efficient nutritional advice from healthcare, adherence to diet patterns, and periodic evaluation may prevent or minimise malnutrition.
  • Duration of seroprotection of the live attenuated SA-14-14-2 Japanese encephalitis vaccine in children in India
    L Preethi, M S Alina, Lakshmi Chandran, S Asvin, M Jagadeesan, T M Vijayakumar, V Chitra, Ashok Kumar Pandey, Mahendra M Reddy, Brij Ranjan Misra, Rajni Kant, Prudhvi Lal Bhukya, Gururaj Rao Deshpande, Priya Abraham, Gajanan Sapkal, Kamran Zaman
    Journal of Travel Medicine, 2023
    Background Acute encephalitis syndrome (AES) is a major public health concern in India, and the Japanese Encephalitis (JE) virus is the most common cause of viral encephalitis in Asia affecting children under the age of 15 years. In India, despite the introduction of the JE vaccine (SA-14-14-2) in the immunization programme, JE continues to account for 15–20% of AES cases to date. This study evaluates the immunogenicity of live attenuated SA-14-14-2 JE vaccine in terms of persistence of the humoral response after two doses. Methods A cross-sectional study was conducted among 266 children belonging to one of the JE endemic regions of Uttar Pradesh, India. Blood samples were taken from children (2–10 years) and grouped according to the duration (in years) after two doses of the vaccine (5 groups with a class interval of 2 years). Informed written consent was obtained from the parents/guardians. All the samples collected were tested for the presence of anti-JEV-specific IgG antibodies by enzyme-linked immunosorbent assay (ELISA) and further confirmed by micro neutralization test (MNT) and immunofluorescence assays. Results Of the 266 samples tested by ELISA for anti-JEV-specific IgG antibodies, 260 (97.74%) were negative and 6 (2.26%) were equivocal. The geometric mean immune status ratio across the five groups, 0–2 years (n = 59), 2–4 years (n = 73), 4–6 years (n = 65), 6–8 years (n = 48) and 8–10 years (n = 21) post-two doses of SA-14-14-2 JE vaccine was 1.143, 1.059, 1.138, 1.075 and 1.130, respectively, and the geometric mean titre obtained from MNT across the five groups was 10.77, 8.400, 8.453, 9.517 and 9.674, respectively. Conclusion The study showed a decreasing trend of anti-JEV specific IgG antibody titres across the five groups based on the duration following two doses of SA-14-14-2 vaccine. The results emphasize the significance of booster doses of vaccine for children living in endemic areas.
  • A Retrospective Study on Drug Utilization Evaluation and Outcomes Assessment in the Department of Nephrology of Tertiary Care Multi speciality Teaching Hospital
    Research Journal of Pharmacy and Technology, 2022
  • A study on prescribing patterns in hemodialysis and renal transplantation patients
    UdayVenkat Mateti, Abdul Nafih, Pradeep Shenoy, Sirimalla Shivaprasad, Jagadeesan Moorthy
    Egyptian Pharmaceutical Journal, 2022
    Background Patients treated with hemodialysis and renal transplant require complex therapy regimens that manage comorbid conditions such as diabetes, hypertension, and so on; as a result, they may develop drug-related issues. Inappropriate medication usage raises the risk of drug related problems, which can manifest as excessively extended hospital stays, higher expenses, and overuse of medical services. Prescribing pattern among the patients treated with hemodialysis and renal transplantation are not well characterized previously. Objectives The objective of the study is to investigate drug prescription trends in hemodialysis patients and to study the prescribing patterns of medications in kidney transplantation patients. Materials and methods The prospective observational study was conducted over a period of 8 months, i.e. from October 2021 to June 2022 in end stage CKD patients treating with maintenance hemodialysis and renal transplant. Different classes of drugs prescribed and percentage of drugs per prescription was estimated in this study. Data were analyzed descriptively. Results 105 patients recruited have been analyzed of which 76 (72.38%) were male and 29 (27.6%) were female. Polypharmacy (use of ≥5 medications) was observed in 91.5% in hemodialysis patients and 100% in renal transplant patients.The most prescribed drugs in hemodialysis patients were Cardiovascular Drugs 72 (100%), and in renal transplant patients, immunosuppressant were highly prescribed 33 (100%). Conclusion This study concludes that the cardiovascular agents and immunosuppressant were the most common drugs prescribed among the hemodialysis and renal transplant patients respectively. polypharmacy among overall patients were observed and it may initiate drug related problems.
  • Rational prescribing challenges in paediatrics: A evidence based review
    M. Jagadeesan, R. HariniR, Balaji Chinnasami
    Research Journal of Pharmacy and Technology, 2020
  • A case report on dengue fever with mental retardation due to consanguineous marriage
    M Jagadeesan, Harini R R, S Kiran Kumar, Sabarathinam Sarvesh, Likhita Yalavarthi
    Research Journal of Pharmacy and Technology, 2019
  • The drug-drug interactions: Affecting the rationality of prescriptions
    M Jagadeesan, R Manikandan, Nandamuri Sri Sai Sudha
    Research Journal of Pharmacy and Technology, 2018
  • A case study on schizophrenia induced multiple comorbidities
    Jagadeesan M, Kiran Kumar R, Justin Jacob Abraham
    Asian Journal of Pharmaceutical and Clinical Research, 2018
    Schizophrenia is a mental disorder characterized by abnormal social behavior which includes false beliefs, confusion, and auditory hallucination. Antipsychotic drugs therapy increases the risk of developing diabetes mellitus and coronary artery disease (CAD) in schizophrenic patients. Hence, we have planned for a systematic approach toward the management of comorbidities induced in schizophrenic patients. A case study was conducted in 42-year-old female patient diagnosed with schizophrenia along with Type-2 diabetes mellitus, hypothyroidism, diabetic retinopathy, diabetic nephropathy, systemic hypertension, CAD-acute coronary syndrome recent inferior wall myocardial infarction. The patient was treated with atypical antipsychotics, antiplatelets, antianginals, statins, hypoglycemic agents, and other supportive measures. The patient improved symptomatically. The antipsychotic treatment for schizophrenia induces abnormal metabolic syndrome which results in decreased glucose and lipid metabolism that leads to obesity, hyperglycemia, and dyslipidemia associated with cardiovascular risks. Often antipsychotics are combined with benzodiazepines and antiparkinson agents to reduce the risks caused from large doses of antipsychotic medication. However, people receiving first-generation antipsychotics have higher prevalence of developing diabetes mellitus and cardiac risks compared to second-generation antipsychotics. Hence, we conclude that atypical antipsychotic drugs such as amisulpride, aripiprazole, and ziprasidone should be given to schizophrenic patients because these drugs have little effects on abnormal metabolic syndrome when compared to other antipsychotics. There is a need for proper screening of blood glucose level and cardiovascular risks assessment before the administration of antipsychotic medications to schizophrenic patients and also during the course of treatment regularly.
  • Comparison of knowledge, attitudes and perceived barriers towards adverse drug reactions reporting between Bachelor of Pharmacy and Doctor of Pharmacy students in Southern India
    Akram Ahmad, Muhammad Umair Khan, Jagadeesan Moorthy, Bandari Deepak Kumar, Gogikar Sudhir Kumar, Isha Patel
    Journal of Pharmaceutical Health Services Research, 2016
  • Comparison of knowledge and attitudes about antibiotics and resistance, and antibiotics selfpracticing between Bachelor of Pharmacy and Doctor of Pharmacy students in Southern India
    Akram Ahmad, Muhammad U Khan, Jagadeesan Moorthy, Shazia Q. Jamshed, Isha Patel
    Pharmacy Practice, 2015
  • A comparison of enoxaparin with unfractionated heparins in patients with coronary heart disease in an emergency department in rural South Indian tertiary care teaching hospital
    Akram Ahmad, Isha Patel, Himani Asani, M Jagadeesan, S Parimalakrishnan, S Selvamuthukumaran
    Indian Journal of Pharmacology, 2015

RECENT SCHOLAR PUBLICATIONS

  • A comparison of the effectiveness of lacosamide and pregabalin in treating patients diagnosed with neuropathic pain: a randomized, controlled, open-label pilot trial
    R Kalpana, WS Robert, F Juzerehaji, R Venkatachalapathy, ...
    Naunyn-Schmiedeberg's Archives of Pharmacology 399 (1), 853-859 , 2026
    2026
    Citations: 2
  • A cross-sectional study on the assessment of nutritional status among young pharmacy students by measuring skinfold thickness
    JM Mohammed Yunas Y
    South Eastern European Journal of Public Health 16 (02), 68-78 , 2025
    2025
  • Degradation-Agnostic Medicine Strip Data Enhancement via Residual Learning
    V Moorthy, J Moorthy, S Saha, A Kumar
    International Conference on ICT for Sustainable Development, 107-116 , 2025
    2025
  • Evaluating the Impact of Personal Habits on Medication Adherence in Patients with Diabetes Mellitus and Hypertension: A Prospective Cross-Sectional Study
    P Velmurugan, JC Thirulochandar, MF Sadiqbasha, J Moorthy
    Biomedical and Pharmacology Journal 18 (2), 1389-1394 , 2025
    2025
  • Patient Health Internet of Things Wearable Device Sensor with Machine Learning for Tracking System
    R Nancy, R Jonathan, J Moorthy, R Latha, R Thangavelu
    2025 International Conference on Electronics and Renewable Systems (ICEARS … , 2025
    2025
    Citations: 1
  • Safety and efficacy of LibidUp-PE supplement on premature ejaculation: A randomized, placebo-controlled double-blind, crossover study
    M Jagadeesan, A Adhisaya
    Pharmaceutical Science Advances 2, 100033 , 2024
    2024
  • Impact of Pharmacist Counseling on Patients Medication Adherence: A Prospective Cross Sectional Study
    JM Sanjeevi Reddy D
    Scope 13, 989-995 , 2023
    2023
  • Challenges in the Pharmacotherapeutic Management of Pulmonary Arterial Hypertension
    JM Mohammed Ismail K S1
    Scope 13, 1053-1062 , 2023
    2023
  • Irrational Fixed Dose Combinations in Current Clinical Practice: A Need of Reconsideration or High Precautions
    JM Akash Ganga R
    Scope 13, 1013-1025 , 2023
    2023
  • Evaluation of Malnutrition by Skinfold Thickness Measurement and SGA-DMS among Haemodialysis Patients: A Cross-Sectional Study
    JMSSV T M
    Journal of Medicinal and Chemical Sciences 6 (12), 3044-3056 , 2023
    2023
  • KNOWLEDGE, ATTITUDE AND PERCEIVED BARRIER TOWARDS EVIDENCE BASED MEDICINE PRACTICE AMONG HEALTH CARE PROFESSIONALS IN SOUTHERN INDIA
    JM Vanishree Senthil, Muoka Jephtha Chidiebere
    European Chemical Bulletin 12 (S2), 2572-2587 , 2023
    2023
  • A study on prescribing patterns in hemodialysis and renal transplantation patients
    JM Abdul Nafiha , Uday Venkat Matetia , Pradeep Shenoyb , Sirimalla Shivaprasada
    Egyptian Pharmaceutical Journal 21 (4), 496-501 , 2022
    2022
    Citations: 2
  • Duration of seroprotection of the live attenuated SA-14-14-2 Japanese encephalitis vaccine in children in India
    L Preethi, MS Alina, L Chandran, S Asvin, M Jagadeesan, ...
    Journal of Travel Medicine 30 (2), taac147 , 2022
    2022
    Citations: 9
  • Do Prescribers Adhere to the Medical Council of India Prescribing Guidelines When Writing the Prescription?
    JM Nihara Parveen M, Suruthy R S, Adhisaya A
    NEUROQUANTOLOGY 20 (16), 260-266 , 2022
    2022
  • A prospective study on prevalence of intradialytic complications and its management in the department of nephrology of tertiary care multispeciality teaching hospital
    VTM Jagadeesan M
    International journal of health Sciences 6 (S7), 2331-2342 , 2022
    2022
  • Eradication of spurious adulterated and under standard quality drugs, a regulatory pertaining in Indian regulatory system
    KTKR Rajesh S, Jothieswari Dhamotharan, Dr. P. Suresh Kumar, M. Arockia Babu ...
    International journal of health Sciences 6 (S8), 1611-1627 , 2022
    2022
  • A Retrospective Study on Drug Utilization Evaluation and Outcomes Assessment in the Department of Nephrology of Tertiary Care Multi speciality Teaching Hospital
    M Jagadeesan, TM Vijayakumar
    Research Journal of Pharmacy and Technology 15 (12), 5626-0 , 2022
    2022
    Citations: 2
  • Prescription Audit and Dispensing Errors in the Outpatient Pharmacy of Tertiary Care Multispecialty Teaching Hospital
    TIAKVRRHLY Jagadeesan M.
    Journal of Pharmaceutical Research International 33 (54B), 303-308 , 2021
    2021
  • Insomnia, Depression and Anxiety among Healthcare workers during Covid-19 Pandemic - An EvidenceBased Review
    JM MUOKA CHIDIEBERE JEPHTHA
    International Journal of Pharmaceutical Research 13 (2), 605-612 , 2021
    2021
    Citations: 1
  • A case study on seizure induced by antkiller poisoning
    JM Karthikeyan K, Ms. Girija S, Ms. Keerthana GC
    Journal of Indian Society of Toxicology 17 (1), 31-34 , 2021
    2021
    Citations: 1

MOST CITED SCHOLAR PUBLICATIONS

  • Comparison of knowledge and attitudes about antibiotics and resistance, and antibiotics self-practicing between Bachelor of Pharmacy and Doctor of Pharmacy students in Southern …
    A Ahmad, MU Khan, J Moorthy, SQ Jamshed, I Patel
    Pharmacy practice 13 (1), 523 , 2015
    2015
    Citations: 57
  • The Drug-Drug Interactions: Affecting the Rationality of Prescriptions
    NSSS Jagadeesan M*, Manikandan R
    Research Journal of Pharmacy and Technology 11 (7), 3077-3080 , 2018
    2018
    Citations: 12
  • Duration of seroprotection of the live attenuated SA-14-14-2 Japanese encephalitis vaccine in children in India
    L Preethi, MS Alina, L Chandran, S Asvin, M Jagadeesan, ...
    Journal of Travel Medicine 30 (2), taac147 , 2022
    2022
    Citations: 9
  • Comparison of knowledge, attitudes and perceived barriers towards adverse drug reactions reporting between Bachelor of Pharmacy and Doctor of Pharmacy students in Southern India
    A Ahmad, MU Khan, J Moorthy, BD Kumar, GS Kumar, I Patel
    Journal of Pharmaceutical Health Services Research 7 (1), 63-69 , 2016
    2016
    Citations: 9
  • Prevalence and pattern of use of complementary and alternative medicine in diabetes patients in a south Indian tertiary care teaching hospital
    SMK K. Shrilatha, Jagadeesan Moorthy, R. R. Harini, A. A. Kaaviya, Sarvesh ...
    Drug Invention today 11 (Special issue 2), 274-279 , 2019
    2019
    Citations: 7
  • Rational Prescribing Challenges in Paediatrics: A Evidence Based Review
    BC Jagadeesan M1*, Harini R R1
    Research Journal of Pharmacy and Technology 13 (11), 5551-5556 , 2020
    2020
    Citations: 6
  • A comparison of enoxaparin with unfractionated heparins in patients with coronary heart disease in an emergency department in rural South Indian tertiary care teaching hospital
    SS Akram Ahmad1,2, Isha Patel3, Himani Asani2, M. Jagadeesan2, S ...
    Indian Journal of Pharmacology 47 (1), 90-94 , 2015
    2015
    Citations: 5
  • A comparison of the effectiveness of lacosamide and pregabalin in treating patients diagnosed with neuropathic pain: a randomized, controlled, open-label pilot trial
    R Kalpana, WS Robert, F Juzerehaji, R Venkatachalapathy, ...
    Naunyn-Schmiedeberg's Archives of Pharmacology 399 (1), 853-859 , 2026
    2026
    Citations: 2
  • A study on prescribing patterns in hemodialysis and renal transplantation patients
    JM Abdul Nafiha , Uday Venkat Matetia , Pradeep Shenoyb , Sirimalla Shivaprasada
    Egyptian Pharmaceutical Journal 21 (4), 496-501 , 2022
    2022
    Citations: 2
  • A Retrospective Study on Drug Utilization Evaluation and Outcomes Assessment in the Department of Nephrology of Tertiary Care Multi speciality Teaching Hospital
    M Jagadeesan, TM Vijayakumar
    Research Journal of Pharmacy and Technology 15 (12), 5626-0 , 2022
    2022
    Citations: 2
  • A Case Report on Dengue Fever with Mental Retardation due to Consanguineous Marriage
    Y Jagadeesan M, Harini R R, Kiran Kumar S, Sabarathinam Sarvesh
    Research journal Pharmacy and Technology 12 (7), 3575-3578 , 2019
    2019
    Citations: 2
  • Patient Health Internet of Things Wearable Device Sensor with Machine Learning for Tracking System
    R Nancy, R Jonathan, J Moorthy, R Latha, R Thangavelu
    2025 International Conference on Electronics and Renewable Systems (ICEARS … , 2025
    2025
    Citations: 1
  • Insomnia, Depression and Anxiety among Healthcare workers during Covid-19 Pandemic - An EvidenceBased Review
    JM MUOKA CHIDIEBERE JEPHTHA
    International Journal of Pharmaceutical Research 13 (2), 605-612 , 2021
    2021
    Citations: 1
  • A case study on seizure induced by antkiller poisoning
    JM Karthikeyan K, Ms. Girija S, Ms. Keerthana GC
    Journal of Indian Society of Toxicology 17 (1), 31-34 , 2021
    2021
    Citations: 1
  • A cross-sectional study on the assessment of nutritional status among young pharmacy students by measuring skinfold thickness
    JM Mohammed Yunas Y
    South Eastern European Journal of Public Health 16 (02), 68-78 , 2025
    2025
  • Degradation-Agnostic Medicine Strip Data Enhancement via Residual Learning
    V Moorthy, J Moorthy, S Saha, A Kumar
    International Conference on ICT for Sustainable Development, 107-116 , 2025
    2025
  • Evaluating the Impact of Personal Habits on Medication Adherence in Patients with Diabetes Mellitus and Hypertension: A Prospective Cross-Sectional Study
    P Velmurugan, JC Thirulochandar, MF Sadiqbasha, J Moorthy
    Biomedical and Pharmacology Journal 18 (2), 1389-1394 , 2025
    2025
  • Safety and efficacy of LibidUp-PE supplement on premature ejaculation: A randomized, placebo-controlled double-blind, crossover study
    M Jagadeesan, A Adhisaya
    Pharmaceutical Science Advances 2, 100033 , 2024
    2024
  • Impact of Pharmacist Counseling on Patients Medication Adherence: A Prospective Cross Sectional Study
    JM Sanjeevi Reddy D
    Scope 13, 989-995 , 2023
    2023
  • Challenges in the Pharmacotherapeutic Management of Pulmonary Arterial Hypertension
    JM Mohammed Ismail K S1
    Scope 13, 1053-1062 , 2023
    2023