On-chip optofluidic cytometer for point-of-care hematology at rural health posts in Kashkadarya, Uzbekistan Kosim Rakhmanov, Olimjon Hujamov, Salim Davlatov, Bakhtiyor Khamdamov, Toxir Askarov, Karim Gaziev, Jasur Hikmatov Proceedings of SPIE the International Society for Optical Engineering, 2026 Reliable hematology testing is critical for diagnosis of anemia, infection and hematologic disorders, yet access to automated analyzers remains limited in rural areas of Central Asia. This study presents the design and field evaluation of an on-chip optofluidic cytometer intended for point-of-care hematology at rural health posts in the Kashkadarya Region of Uzbekistan. The device integrates sample metering, plasma–cell separation, hydrodynamic focusing and imaging-based cell enumeration on a single microfluidic cartridge coupled to a compact optical reader. Capillary blood is introduced directly without external preparation, and red cells, white cells and platelets are quantified from transmitted and scattered light signatures using embedded algorithms. In a prospective deployment across multiple health posts, cytometer performance was compared with reference laboratory analyzers and manual microscopy. The on-chip system achieved clinically acceptable accuracy and precision, reduced time to result and required minimal operator training, supporting its potential role in decentralised hematology services in resource-constrained rural settings.
Environmental noise pollution and 24-hour blood pressure variability: a cross-sectional analysis in urban industrial zones Tuktash Qurbonov, Ollabergan Allaberganov, Ramziya Achilova, Jasur Hikmatov, Shoira Xazratkulova, et al. Revista Latinoamericana De Hipertension, 2025 The noise pollution of the kind experienced in urban industrial settlements, as one of the major stressors, has negative effect on cardiovascular health, but its association with 24-hour blood pressure variability has been poorly investigated. In this cross-sectional study, an effort was made to assess the relationship between noise pollution and blood pressure variability in 400 urban industrial settlement residents of Uzbekistan. Blood pressure measurements were collected using ambulatory blood pressure monitoring (ABPM) and noise levels with calibrated decimeters (Leq) for 24 hours. Results showed the noisy group (Leq 62.7–72.4 dB) had higher systolic and diastolic blood pressures (132.5 vs. 128.7 mmHg and 82.3 vs. 79.8 mmHg) and higher blood pressure variability (systolic standard deviation 14.8 vs. 12.9 mmHg) compared to the low-noise group. The prevalence of non-dipping (nocturnal BP fall of <10%) was 60% in the noisy group (odds ratio 2.25) versus 40% in the low-noise group. Subgroup analysis identified elderly individuals, women, and smokers as most vulnerable to noise. Increased cortisol (15.2 vs. 13.5 μg/dL) and reduced heart rate variability in the noisy group reconfirmed physiological stress. These findings stress the need to reduce noise in industrial areas for improved cardiovascular health and suggest policies such as the introduction of noise barriers. Longitudinal studies are necessary to determine these relationships.
RECENT SCHOLAR PUBLICATIONS
Environmental noise pollution and 24-hour blood pressure variability: a cross-sectional analysis in urban industrial zones. T Qurbonov, O Allaberganov, R Achilova, J Hikmatov, S Xazratkulova, ... Revista Latinoamericana de Hipertensión 20 (9) , 2025 2025 Citations: 1
THE SCIENTIFIC BASIS OF THE IMPORTANCE OF THE SANITATION BRONCHOSCOPY METHOD IN THE TREATMENT OF BRONCHIECTASIS J Hikmatov AMERICAN JOURNAL OF APPLIED MEDICAL SCIENCE 2 (4), 167-178 , 2024 2024
Immunological Basis of Etiopathogenesis and Treatment of Bronchiectasis HJ Safarovich International Journal of Integrative and Modern Medicine 2 (7), 194-202 , 2024 2024
THE ROLE OF BRONCHOLOGICAL SANITATION IN THE TREATMENT OF BRONCHIECTASIS JS Hikmatov World Bulletin of Public Health 36, 24-30 , 2024 2024
Бронхоэктазияни комплекс жарроҳлик даволашнинг бир қисми сифатида иммунотерапияда дифференциярланган ёндашув Ж Ҳикматов, Ш Солиева Профилактическая медицина и здоровье 3 (2), 36-41 , 2024 2024
Sanative Bronchoscopy: Significance in the Treatment of Bronchiectatic Disease JS Hikmatov, BZ Khamdamov American Journal of Medicine and Medical Sciences 14 (11), 2804-2809 , 2024 2024 Citations: 2
EXPERIMENTAL DEVELOPMENT OF DIAGNOSTIC CRITERIA FOR WOUND PROCESS PHASES IN EXPERIMENTAL ANIMALS WITH DIABETES MELLITUS BZ Khamdamov, AT Dekhqonov, JS Hikmatov, AB Khamdamov EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE 3 (12), 356-369 , 2023 2023
IMMUNOLOGICAL APPROACHES TO THE PATHOGENESIS AND TREATMENT OF BRONCHIECTATIC DISEASE HJ Safarovich EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE 3 (12), 399-407 , 2023 2023
THE ROLE OF VIRTUAL AND SIMULATION TECHNOLOGIES IN THE ORGANIZATION OF QUALITY MEDICAL EDUCATION J Hikmatov JOURNAL OF MULTIDISCIPLINARY BULLETIN 6 (4), 56-60 , 2023 2023
Use of the mos sf-36 questionnaire in the assessment of quality of life in surgery HJ Safarovich Journal of applied medical sciences 6 (4), 49-55 , 2023 2023 Citations: 4
USE OF INTERACTIVE METHODS IN TEACHING STUDENTS OF THE MEDICAL INSTITUTE HJ Safarovich PEDAGOG 6 (6), 539-544 , 2023 2023
TIBBIYOT INSTITUTI TALABALARINI OʻQITISHDA INTERFAOL USULLARDAN FOYDALANISH H Jasur 2023
Median abdominal hernia: etiology, modern diagnosis and treatment JS Hikmatov, SO Komilov Finland International Scientific Journal of Education, Social Science … , 2023 2023
The role of modern research in improving the results of carotid endarterectomy in patients with high surgical risk ME Ochilov European journal of modern medicine and practice 3 (12), 379-382 , 2023 2023
Tibbiyot instituti talabalarini oʻqitishda interfaol usullardan foydalanish JS Hikmatov Involta Scientific Journal 2 (5), 54-59 , 2023 2023
Топинамбур как средство для лечения сахарного диабета СО Комилов, ЖС Хикматов, МТ Сафарова Биология и интегративная медицина, 58-62 , 2023 2023 Citations: 1
КЕКСАЛАРДА ТЎҒРИ ВА СОҒЛОМ ОВҚАТЛАНИШ ТАМОЙИЛЛАРИ СО Комилов, ЖС Хикматов, МТ Сафарова Биология и интегративная медицина, 51-57 , 2023 2023
ДИФФЕРЕНЦИРОВАННОЕ ЛЕЧЕНИЕ ЭРЕКТИЛЬНОЙ ДИСФУНКЦИИ ПРИ ХРОНИЧЕСКИХ ОККЛЮЗИОННЫХ ЗАБОЛЕВАНИЯХ БРЮШНОЙ АОРТЫ СО Комилов, ЖС Хикматов Достижения науки и образования, 79-83 , 2023 2023
РАК МОЛОЧНОЙ ЖЕЛЕЗЫ У МУЖЧИН КАК РЕДКОЕ ВСТРЕЧАЕМОСТИ ЗАБОЛЕВАНИЕ ЖС Хикматов, КУ Газиев O'ZBEKISTONDA FANLARARO INNOVATSIYALAR VA ILMIY TADQIQOTLAR JURNALI 2 (14 … , 2022 2022
Хирургияда ҳаёт сифатини баҳолашда MOS SF-36 сўровномадан фойдаланиш ҲЖ Сафарович O'zbekistonda fanlararo innovatsiyalar va ilmiy tadqiqotlar jurnali 2 (14 … , 2022 2022
MOST CITED SCHOLAR PUBLICATIONS
Новое в химиотерапии эхиноккокоза печени ИА Мирходжаев, ЖС Хикматов Биология и интегративная медицина, 78-88 , 2021 2021 Citations: 11
Influence of intestinal microflora on the development of gallstone disease (literature review) HJ Safarovich Вопросы науки и образования, 29-40 , 2021 2021 Citations: 7
Множественный и сочетанный эхинококкоз как причина рецидивов РМ Ахмедов, ББ Муаззамов, ШУ Шарипова, ЖС Хикматов Хирургия Узбекистана, 15-16 , 2016 2016 Citations: 7
Изучение основных сывороточных цитокинов у больных эхинококкозом печени.«Современные технологии и интенсивной терапии» ИА Мирходжаев, ЖС Хикматов, АИ Нуритов Научная статья. Саранск 137 , 2015 2015 Citations: 7
Оптимизация методов хирургического лечения множественных и рецидивных форм эхинококка печени СО Комилов, ИА Мирходжаев, ЖС Хикматов Новый день в медицине, 32 , 2021 2021 Citations: 6
" Влияние аллогернио-протезирования вентральных грыж на показатели качество жизни больных БЗ Хамдамов, ИА Мирходжаев, ЖС Хикматов Проблемы биологии и медицины, 91 , 2018 2018 Citations: 5
Изучение влияния аллогерниопротезирования вентральных грыж на показатели качества жизни больных ИА Мирходжаев, ФХ Норов, ЖС Хикматов Биология и интегративная медицина, 11-19 , 2016 2016 Citations: 5
Use of the mos sf-36 questionnaire in the assessment of quality of life in surgery HJ Safarovich Journal of applied medical sciences 6 (4), 49-55 , 2023 2023 Citations: 4
Современные взгляды на проведение герниопластики при послеоперационных вентральных грыжах ББ Муаззамов, УХ Юлдашев, ЖС Хикматов Хирургия Узбекистана 3, 46-47 , 2016 2016 Citations: 4
Современные подходы к профилактике тромбоэмболических осложнений гигантских грыж ИА Мирходжаев, СО Комилов, ЖС Хикматов Научная статья. Саранск, 140-143 , 2015 2015 Citations: 4
Bronchiectasis disease: etiology, pathogenesis, modern diagnosis and treatment JS Hikmatov Новости образования: исследование в XXI веке 1, 1048-1064 , 2022 2022 Citations: 3
Sanative Bronchoscopy: Significance in the Treatment of Bronchiectatic Disease JS Hikmatov, BZ Khamdamov American Journal of Medicine and Medical Sciences 14 (11), 2804-2809 , 2024 2024 Citations: 2
Улучшение Результатов Комбинированного Плевродеза При Видеоторакоскопических Вмешательствах У Больных С Буллезной Болезнью Легких Ш Худайбергенов, О Эшонходжаев, Ж Исматов, Ж Ҳикматов CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, 343-48 , 2021 2021 Citations: 2
Особенности диагностики и пути улучшения результатов хирургического лечения эхинококкоза печени ИА Мирходжаев, ЖС Хикматов Вестник науки и образования, 60-65 , 2020 2020 Citations: 2
Хирургияда вентрал чурраларда ўтказиладиган протезли пластика амалиёти натижаларини яхшилаш йўллари: Магистерская диссертация / Жасур Сафарович Хикматов; науч. рук. И.А.Мирходжаев ЖС ХИКМАТОВ Бухарский государственный медицинский институт имени Абу Али ибн Сино , 2016 2016 Citations: 2
Environmental noise pollution and 24-hour blood pressure variability: a cross-sectional analysis in urban industrial zones. T Qurbonov, O Allaberganov, R Achilova, J Hikmatov, S Xazratkulova, ... Revista Latinoamericana de Hipertensión 20 (9) , 2025 2025 Citations: 1
