JUn Zheng
@uni-freiburg.de
University of Freiburg
Institute of Organic Chemistry
Jun was born in changzhou, jiangsu province in 1989. He received his B.Sc. in Chemistry from Soochow University in 2011. He began his graduate studies at Shanghai Institute of Organic Chemistry working with Professor Shu-Li You on the development of rhodium-catalyzed asymmetric C-H functionalization. In 2016, he moved to University of Freiburg and joined the laboratory of Professor Bernhard Breit. His postdoctoral research included palladium catalyzed direct allylic alkylation of electron-deficient (hetero)arenes with alkynes and stereoselective hydroaminoalkylation of alkynes and allenes by using a combined rhodium/photoredox catalytic system.
EDUCATION
2016-2019 University of Freiburg
Alexander von humboldt Postdoc Fellowship
Advisor: Prof. Dr. B. Breit
2011-2016 Shanghai Institute of Organic Chemistry
Ph.D in Organic Chemistry
Advisor: Prof. Shu-li You
2007-2011 Soochow university
B.Sc. in Chemistry
RESEARCH INTERESTS
My research focuses on exploring novel catalytic system for the rapid and efficient construction of small molecules. Of great importance is that the methods are highly selective, which covers chemoselectivity, regioselectivity and enantioselectivity. I am particularly interested in exploring atom-economic, environment friendly and redox-neutral transformations enabling efficient and selective preparation of complex molecules and biologically privileged structural motifs. I am specifically involved in rhodium-catalyzed asymmetric C-H functionalization, novel cross-coupling reactions enabled by a dual TM/photoredox catalysis.
Scholar Citations
Scholar h-index
Scholar i10-index
RECENT SCHOLAR PUBLICATIONS
MOST CITED SCHOLAR PUBLICATIONS
Publications
J. Zheng, S.-L. You,* Rhodium-catalyzed direct coupling of biaryl pyridine derivatives with internal alkynes. Chem. Commun. 2014, 50, 8204-8207.
J. Zheng, S.-L. You,* Construction of Axial Chirality by Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes. Angew. Chem. Int. Ed. 2014, 53, 13244-13247.
J. Zheng, S.-B. Wang, C. Zheng, S.-L. You,* Asymmetric Dearomatization of Naphthols via a Rh-Catalyzed C(sp2)–H Functionalization/Annulation Reaction. J. Am. Chem. Soc. 2015, 137, 4880-4883.(Highlighted by Synfacts 2015, 11(7),0721)
Q. Yin, S.-G. Wang, X.-W. Liang, D.-W. Gao, J. Zheng, S.-L. You, * Organocatalytic Asymmetric Chlorinative Dearomatization of Naphthols. Chem. Sci. 2015, 6, 4179-4183.
C. Zheng, * J. Zheng, S.-L. You,* A DFT Study on Rh-Catalyzed Asymmetric Dearomatization of 2-Naphthols Initiated with C–H Activation: A Refined Reaction Mechanism and Origins of Multiple Selectivity. ACS Catal. 2016, 6 (1), 262-271.
D.-W. Gao, J. Zheng, K.-Y. Ye. C. Zheng, S.-L. You,* Asymmetric Functionalization of C-H Bonds, Chapter 5. Asymmetric Functionalization of C-H Bonds via a Transient Carbon-Metal (C-M) Species, 2015, 141-213.
J. Zheng, W.-J. Cui, C. Zheng, S.-L. You,* Synthesis and Application of Chiral Spiro Cp Ligands in RhodiumCatalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes. J. Am. Chem. Soc. 2016, 138, 5242-5245.
S,-B. Wang, J. Zheng, S,-L. You,* Synthesis of Ferrocene-based Pyridinones through Rh(III)-Catalyzed Direct C-H Functionalization Reaction. Organometallics 2016, 35, 1420-1425.
J. Zheng, S.-B. Wang, C. Zheng, S.-L. You,* Asymmetric Synthesis of Spiropyrazolones by Rhodium-Catalyzed C(sp2)–H Functionalization/Annulation Reactions. Angew. Chem. Int. Ed. 2017, 56, 4540-4544. (Highlighted by Synfacts 2017, 13(6), 0609).
J. Zheng, B. Breit,* Palladium-Catalyzed Direct C-H Allylation of Electron-Deficient Polyfluoroarenes with Alkynes. Org. Lett. 2018, 20, 1866-1870.
J. Zheng, F. Hosseini-Eshbala, Y.-X. Dong, B. Breit,* Palladium-Catalyzed Trisallylation of Azoles with Alkyne via sequential C(sp2)-H and C(sp3)-H Functionalization. Chem. Commun. 2019, 55, 624-627.
J. Zheng, B. Breit,* Regiodivergent Hydroaminoalkylation of Alkynes and Allenes by a Combined Rhodium and Photoredox Catalytic System. Angew. Chem. Int. Ed. 2019, 58, 3392-3397.
J. Zheng, B. Worl, B. Breit,* Rhodium-Catalyzed Chemo-, Regio-, and Enantioselective Allylation of 2-Aminothiazoles with Terminal Allenes. Eur. J. Org. Chem. 2019, DOI: 10.1002/.
GRANT DETAILS
2017-2020 Alexander von humboldt Fellowship
2017 Chinese Academy of Sciences (CAS) 100 outstanding PhD thesis
2016 SABIC-CAS scholarship; CAS President Award
2015 Wangyou excellent Ph.D. Scholarship in CAS
2015 Won the title of excellent student in CAS
2011 Outstanding graduates of Soochow University
2011 Second-Class Scholarship of Soochow University
2010 First-Class Scholarship of Soochow University
2009 First-Class Scholarship of Soochow University
2008 Third-Class Scholarship of Soochow University
RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)
You, S.-L.; Zheng, J.; Cui, W.-J. Based on the spiro skeleton of cyclopentadiene compounds and their rhodium complex, preparation and application, Chinese Patent, 201610120414.7.