Luis Antonio Justulin Jr

Scopus Publications

Renal proteomics of male offspring exposed to maternal protein restriction: molecular, epigenetic, and nephron-specific signatures of metabolic programming
Danielle Amanda Niz Alvarez, Isabelle Tenori Ribeiro, Matheus Naia Fioretto, Marina Pereira Pires, Luisa Annibal Barata, et al.
Journal of Physiology and Biochemistry, 2026
Chronic kidney disease is an increasing global public health concern, and the Developmental Origins of Health and Disease (DOHaD) concept proposes that adverse conditions during critical developmental windows predispose offspring to chronic disorders later in life. Maternal protein restriction (MPR), a well-established experimental model reflecting food insecurity, has been shown to impair nephrogenesis and promote long-term renal dysfunction. In this study, we investigated renal metabolic–epigenetic programming induced by gestational and lactational MPR in post-weaning male rats using a global kidney proteomic approach. MPR altered renal structure and profoundly dysregulated protein networks, characterized by downregulation of energy metabolism, ion transport, cytoskeletal organization, membrane integrity, and mitochondrial function, alongside upregulation of innate immune pathways, glutathione metabolism, vesicular trafficking, and cytoskeletal dynamics. Integrated pathway and disease enrichment analyses revealed the potential risk to hypertension, acid–base imbalance, renal tubular transport disorders, nephrosis, and renal failure. Key differentially expressed proteins (e.g., GPX1, CYCS, ATP1A2/ATP1B1, TUBB/TUBA isoforms, ANPEP, and metabolic enzymes) emerged as potential biomarkers of renal metabolic–epigenetic programming. Collectively, these findings identify molecular signatures that link early-life protein restriction to long-term risk of kidney disease and provide mechanistic insight into the nephron- and cell-specific consequences of MPR.
Placental programming in maternal malnutrition as a crucial determinant of offspring health: A critical-interpretative narrative review
Luisa Annibal Barata, Matheus Naia Fioretto, Natália Magosso, Flávia Alessandra Maciel, Isabelle Tenori Ribeiro, et al.
Clinical Nutrition Espen, 2026
Nanoplastic-driven white pollution: Biochemical insights into ecosystem and human health impacts - a critical-interpretative narrative review
Matheus Naia Fioretto, Natália Magosso, Patrick Vieira de Souza, Mirella Franco Moreira, Vanessa Aguiar Rocha, et al.
Biochimie, 2026
Understanding Intracellular Transport Impairments in Maternal Protein Restriction: A Scoping Review of DOHaD-Driven Cellular Biology Perspective
Matheus Naia Fioretto, Isabelle Tenori Ribeiro, Maria Clara Caruso Corso, Sofia Francisco Tellaroli, Carla Beatriz Correa de Souza, et al.
Cell Biochemistry and Biophysics, 2026
Phytochemical frontiers and molecular targets in liver cancer: A systematic bibliometric curation of natural compounds for HCC therapy (2015–2025)
Biomedicine and Pharmacotherapy, 2026
Protein Restriction During Pregnancy and Lactation Triggers Steatohepatitis and Adrenal Disorders in Rat Dams: Insights into Maternal Metabolic Health
Luísa Annibal Barata, Matheus Naia Fioretto, Vinícius Alexandre de Andrade Felipe, Patrick Vieira de Souza, Isabelle Tenori Ribeiro, et al.
Archives of Medical Research, 2026
Omics-based molecular signatures of adrenal, kidney, and lung development in male rat offspring exposed to maternal protein restriction
Matheus N. Fioretto, Marcel R. Ferreira, Gabriel H. Caxali, Patrick V. de Souza, Flávia A. Maciel, et al.
Clinical Nutrition, 2026
Gestational and lactational exposure to phthalates and nanoplastics induces inflammation and oxidative imbalance in the prostate of adult rats
Vanessa A Rocha, Marina Cavalheiro, Patrick V Souza, Natalia Magosso, Matheus N Fioretto, et al.
Toxicological Sciences an Official Journal of the Society of Toxicology, 2026
The intrauterine microenvironment is highly susceptible to environmental disturbances, which may result in persistent effects on offspring health. Given that plastic-derived contaminants can cross the placental barrier and act as endocrine-disrupting chemicals, this study evaluated the effects of perinatal exposure to an environmentally relevant phthalate mixture (PM) and nanoplastics (NPs) on the prostate of adult rats. Pregnant Sprague–Dawley rats were allocated into 6 experimental groups: Ctrl (vehicle), T1 (20 μg/kg/d PM), T2 (200 mg/kg/d PM), T3 (NPs: 1.0 mg/kg/d), T4 (20 μg PM + NPs), and T5 (200 mg PM + NPs). Treatments were administered orally from gestational day 10 to postnatal day (PND) 21. Male offspring were euthanized on PND120, and ventral prostate samples were collected. Histological evaluation revealed increased inflammatory foci and stromal expansion in all exposed groups (T1–T5), along with reduced luminal compartment in T1, T3, and T4 compared with controls. All treated groups showed increased total and degranulated mast cells and enhanced androgen receptor immunoreactivity. Tumor necrosis factor (Tnf) expression was increased in all exposure groups, whereas Rela gene expression was elevated in the T4 and T5 groups. Oxidative stress analysis demonstrated increased lipid peroxidation and glutathione S-transferase (GST) activity in all treated animals. Catalase (CAT) activity was reduced in T1, T3, and T5, whereas superoxide dismutase (SOD) activity increased in T3, T4, and T5. Elevated levels of reduced, oxidized, and total glutathione (GSH, GSSG, tGSH) were observed in T5. Overall, perinatal exposure to PM and NPs induced persistent inflammation and altered redox status in the prostate, increasing susceptibility to pathological disorders.
Review: The Protective Impact of Supplementation and Exercise against Maternal Malnutrition: Environment as a Key Determinant of Health or Disease
Matheus Naia Fioretto, Isabelle Tenori Ribeiro, Luis Antonio Justulin
Cell Biochemistry and Biophysics, 2026
Endocrine programming of the pituitary–thyroid–adrenal axis: Sex-Specific effects of maternal malnutrition in rats
Ana Lívia Silvério Vieira, Gustavo Monezzi Cordeiro, Vinicius Alexandre de Andrade Felipe, Matheus Naia Fioretto, Luísa Annibal Barata, et al.
Molecular and Cellular Endocrinology, 2026
Metabolic insights into male fertility: a narrative review of the role of adiponectin on the hypothalamic–pituitary–testicular axis
Ana Luiza Romano Gabriel, Matheus Naia Fioretto, Luisa Annibal Barata, Luis Antonio Justulin, Sergio Luis Felisbino
Biology of Reproduction, 2026
Maternal Phthalate Exposure Alters Prostate Proteome in Rat Offspring: Linking Omics Insights to Prostate Cancer Risk in Humans
Patrick Vieira Souza, Ariana Musa Aquino, Luiz Guilherme Alonso-Costa, Natália Magosso, Marcos Antonio Fernandes de Oliveira, et al.
Archives of Medical Research, 2026
Current insights into the impact of plastic-derived pollutants (phthalates), microplastics, and nanoplastics on hypothalamic phenotype and molecular pathways: A scoping review
Matheus Naia Fioretto, Victória Cristina Pinha, Carolina Beatriz Pinheiro Basso, Patrick Vieira de Souza, Natália Magosso, et al.
Environmental Pollution, 2026
Supplementation with inorganic iron has no impact on the morphology of the hypopharyngeal glands in honey bees (Apis mellifera L.)
Alex Junji Shinohara, Thaís de Souza Bovi, Guilherme Duarte Figueiredo de Souza, Daniel Nicodemo, Luis Antônio Justulin Júnior, et al.
Acta Scientiarum Animal Sciences, 2026
Correction: Peroxiredoxins in the Developmental Origins of Health and Disease: Insights from Maternal Under and Overnutrition – A Critical-Interpretative Scoping Review (Cell Biochemistry and Biophysics, (2026), 10.1007/s12013-026-02061-9)
Matheus Naia Fioretto, Luísa Correia Gomes, Flávia Alessandra Maciel, Ana Luiza Silva de Abreu, Ana Luiza Romano Gabriel, et al.
Cell Biochemistry and Biophysics, 2026
Peroxiredoxins in the Developmental Origins of Health and Disease: Insights from Maternal Under and Overnutrition – A Critical-Interpretative Scoping Review
Matheus Naia Fioretto, Luísa Correia Gomes, Flávia Alessandra Maciel, Ana Luiza Silva de Abreu, Ana Luiza Romano Gabriel, et al.
Cell Biochemistry and Biophysics, 2026
Maternal Exposure to an Environmentally Relevant Phthalate Mixture Modulates the Steroidogenic Genes in the Adrenal Glands Throughout Postnatal Development of Male Rats
Natália Magosso, Patrick Vieira de Souza, Ariana Musa Aquino, Vanessa Aguiar Rocha, Matheus Naia Fioretto, et al.
Environmental Toxicology, 2025
Early and long-term effects of maternal protein restriction on offspring organs and systems: insights from the developmental origins of health and disease (DOHaD)
Matheus Naia Fioretto, Luisa Annibal Barata, Isabelle Tenori Ribeiro, Flávia Alessandra Maciel, Renato Mattos, et al.
Biogerontology, 2025
Maternal protein restriction compromises hepatic phenotype and antioxidant defense in postweaning male rats, while females exhibit resilience
André Matheus Leandro Franzolin, Matheus Naia Fioretto, Isabelle Tenori Ribeiro, Flávia Alessandra Maciel, Luisa Annibal Barata, et al.
Biochemical and Biophysical Research Communications, 2025
Maternal malnutrition induces inflammatory pathways and oxidative stress in the dorsolateral prostate of male offspring rats
Renato Mattos, Matheus Naia Fioretto, Sérgio Alexandre Alcantara dos Santos, Isabelle Tenori Ribeiro, Maycon Tavares Emílio-Silva, et al.
Biogerontology, 2025
Long-term effects of maternal protein restriction on adrenal proteomic profile and steroidogenesis in male offspring rats
Matheus Naia Fioretto, Luísa Annibal Barata, Vinícius Alexandre de Andrade Felipe, Sérgio Alexandre Alcantara dos Santos, Flávia Alessandra Maciel, et al.
Cellular Signalling, 2025
A high-fat diet changes the interaction of the extracellular matrix, cytokines, and growth factors in gastric ulcer repair
Rie Ohara, Felipe Lima Dario, Maycon Tavares Emílio-Silva, Renata Assunção, Vinícius Peixoto Rodrigues, et al.
Biochemical and Biophysical Research Communications, 2025
Maternal protein restriction and postnatal sugar consumption increases inflammatory response and deregulates metabolic pathways in the liver of male offspring rats with aging
Isabelle Tenori Ribeiro, Matheus Naia Fioretto, Sérgio Alexandre Alcantara dos Santos, Marcus Vinicius Niz Alvarez, Luiz Marcos Frediani Portela, et al.
Molecular and Cellular Endocrinology, 2025
Aerobic exercise acts differentially on proteins from glucose and glycogen pathways in the SOL and PL muscles of offspring rats submitted to a low-protein maternal diet
Jéssica Silvino Valente, Ketlin Thassiani Colombelli, Lucas Lins Pereira, Érika Stefani Perez, Bruna Tereza Thomazini Zanella, et al.
Biochemical and Biophysical Research Communications, 2025
Maternal protein restriction impairs intestinal morphophysiology and antioxidant system in young male offspring rats
Isabela Baptista Leal dos Santos, Matheus Naia Fioretto, Miguel Silingardi Jorge, Luísa Annibal Barata, Isabelle Tenori Ribeiro, et al.
Experimental Cell Research, 2025
Maternal hyperglycemia and postnatal high-fat diet impair metabolic regulation and autophagy response in the liver of adult female rats
Larissa Lopes da Cruz, Yuri Karen Sinzato, Verônyca Gonçalves Paula, Matheus Naia Fioretto, Franciane Quintanilha Gallego, et al.
Journal of Developmental Origins of Health and Disease, 2025
Long Noncoding RNAs Responding to Ethanol Stress in Yeast Seem Associated with Protein Synthesis and Membrane Integrity
Amanda Piveta Schnepper, Agatha M. S. Kubo, Camila Moreira Pinto, Ramon Hernany Martins Gomes, Matheus Naia Fioretto, et al.
Genes, 2025
Type I and type III collagen immunoexpression in rabbit skin biopsy samples treated with rosuvastatin gel and autologous platelet-rich plasma
Cristoffer da Silva Santana, M. R. S. Breda, Yuri Ferreira Vicentini, S. A. A. Santos, L. A. Justulin, et al.
Acta Cirurgica Brasileira, 2025
Engineering a 3D platform for testis bioengineering: generation and proteomic profiling of decellularized fish testicular scaffolds
Ivana Felipe Rosa, Beatriz Marques Souza, Lucas Benites Doretto, Maira da Silva Rodrigues, Caroline Nascimento Barquilha, et al.
Frontiers in Bioengineering and Biotechnology, 2025
Citral protects against metabolic endotoxemia, and systemic disorders caused by high-fat diet-induced obesity via intestinal modulation
Maycon Tavares Emílio-Silva, Vinicius Peixoto Rodrigues, Mariana Moraes Fioravanti, Antonio Jesús Ruiz-Malagon, Matheus Naia Fioretto, et al.
Frontiers in Pharmacology, 2025
Influence of aging and maternal protein restriction on PIWI-interacting RNA expression in the offspring rat ventral prostate
Hecttor S. Baptista, Luiz M. Frediani Portela, Matheus N. Fioretto, Renato Mattos, Isabelle T. Ribeiro, et al.
Scientific Reports, 2024
In Silico Analysis of Non-Conventional Oxidative Stress-Related Enzymes and Their Potential Relationship with Carcinogenesis
Fábio Rodrigues Ferreira Seiva, Maria Luisa Gonçalves Agneis, Matheus Ribas de Almeida, Wesley Ladeira Caputo, Milena Cremer de Souza, et al.
Antioxidants, 2024
Maternal protein restriction combined with postnatal sugar consumption alters liver proteomic profile and metabolic pathways in adult male offspring rats
Isabelle Tenori Ribeiro, Matheus Naia Fioretto, Sérgio Alexandre Alcantara dos Santos, Ketlin Thassiani Colombelli, Luiz Marcos Frediani Portela, et al.
Molecular and Cellular Endocrinology, 2024
Impact of maternal protein restriction on the proteomic landscape of male rat lungs across the lifespan
Matheus Naia Fioretto, Flávia Alessandra Maciel, Luísa Annibal Barata, Isabelle Tenori Ribeiro, Carolina Beatriz Pinheiro Basso, et al.
Molecular and Cellular Endocrinology, 2024
Vascular smooth muscle cells exhibit elevated hypoxia-inducible Factor-1α expression in human blood vessel organoids, influencing osteogenic performance
Geórgia da Silva Feltran, Rodrigo Augusto da Silva, Célio Junior da Costa Fernandes, Marcel Rodrigues Ferreira, Sérgio Alexandre Alcântara dos Santos, et al.
Experimental Cell Research, 2024
Insulin signaling and mitochondrial phenotype of skeletal muscle are programmed in utero by maternal diabetes
Eduardo Klöppel, Larissa L. Cruz, Laura F.L. Prado-Souza, Adam Eckhardt, José E. Corrente, et al.
Molecular and Cellular Endocrinology, 2024
Maternal malnutrition associated with postnatal sugar consumption increases inflammatory response and prostate disorders in rat offspring
Matheus Naia Fioretto, Ketlin Thassiani Colombelli, Cecilia Luvizutti Ferreira da Silva, Sérgio Alexandre Alcantara dos Santos, Ana Carolina Lima Camargo, et al.
Molecular and Cellular Endocrinology, 2024
In silico investigation of the role of miRNAs in a possible developmental origin of prostate cancer in F1 and F2 offspring of mothers exposed to a phthalate mixture
A. M. Aquino, M. N. Fioretto, L. G. Alonso‐Costa, V. A. Rocha, P. V. Souza, et al.
Environmental Toxicology, 2024
The joint action of yeast eisosomes and membraneless organelles in response to ethanol stress
Camila Moreira Pinto, Amanda Piveta Schnepper, Pedro Henrique Esteves Trindade, Luiz Henrique Cardoso, Matheus Naia Fioretto, et al.
Heliyon, 2024
Deregulation of ABCG1 early in life contributes to prostate carcinogenesis in maternally malnourished offspring rats
Ana CL. Camargo, Flávia B. Constantino, Sergio AA. Santos, Ketlin T. Colombelli, Luiz MF. Portela, et al.
Molecular and Cellular Endocrinology, 2024
Non-invasive biomagnetic assessment of gastrointestinal motility in a loperamide-induced constipation model
Erick Guilherme Stoppa, Guilherme Augusto Soares, Lais Pereira Buranello, Luiz Marcos Frediani Portela, Luiz Antônio Justulin, et al.
Brazilian Journal of Pharmaceutical Sciences, 2024
Early-life origin of prostate cancer through deregulation of miR-206 networks in maternally malnourished offspring rats
Luiz M. F. Portela, Flavia B. Constantino, Ana C. L. Camargo, Sérgio A. A. Santos, Ketlin T. Colombelli, et al.
Scientific Reports, 2023
Integrated transcriptome and proteome analysis indicates potential biomarkers of prostate cancer in offspring of pregnant rats exposed to a phthalate mixture during gestation and lactation
A.M. Aquino, L.G. Alonso-Costa, S.A.A. Santos, V.A. Rocha, L.F. Barbisan, et al.
Chemosphere, 2023
Zinc methionine or zinc sulphate supplementation modulate the development of the hypopharyngeal gland and expression of major royal jelly protein genes in Apis mellifera L. bees
Giovanna do Prado Ribeiro, Samir Moura Kadri, Luis Antônio Justulin, Paulo Eduardo Martins Ribolla, Ricardo de Oliveira Orsi
Physiological Entomology, 2023
2,4-dichlorophenoxyacetic acid (2,4-D) exposure during postnatal development alters the effects of western diet on mouse prostate
V.A. Rocha, A.M. Aquino, N. Magosso, P.V. Souza, L.A. Justulin, et al.
Reproductive Toxicology, 2023
Hyperglycemic microenvironment compromises the homeostasis of communication between the bone-brain axis by the epigenetic repression of the osteocalcin receptor, Gpr158 in the hippocampus
Ericka Patricia da Silva, Geórgia da Silva Feltran, Sérgio Alexandre Alcântara dos Santos, Rodrigo Cardoso de Oliveira, Rahyza I.F. Assis, et al.
Brain Research, 2023
Integrative Analysis of the Ethanol Tolerance of Saccharomyces cerevisiae
Ivan Rodrigo Wolf, Lucas Farinazzo Marques, Lauana Fogaça de Almeida, Lucas Cardoso Lázari, Leonardo Nazário de Moraes, et al.
International Journal of Molecular Sciences, 2023
Editorial: Early Life Epigenetic Programming of Health and Disease through DOHaD Perspective
Luis A. Justulin, Elena Zambrano, Thomas P. Ong, Susan E. Ozanne
Frontiers in Cell and Developmental Biology, 2023
miR-18a-5p Is Involved in the Developmental Origin of Prostate Cancer in Maternally Malnourished Offspring Rats: A DOHaD Approach
Sergio Alexandre Alcantara Santos, Luiz Marcos Frediani Portela, Ana Carolina Lima Camargo, Flavia Bessi Constantino, Ketlin Thassiani Colombelli, et al.
International Journal of Molecular Sciences, 2022
Effects of a phthalate metabolite mixture on both normal and tumoral human prostate cells
Alexandre M. B. Cavalca, Ariana M. Aquino, Francielle C. Mosele, Luis A. Justulin, Flávia K. Delella, et al.
Environmental Toxicology, 2022
Bisphenol A and 2,3,7,8-tetrachlorodibenzo-p-dioxin at non-cytotoxic doses alter the differentiation potential and cell function of rat adipose-stem cells
Helga Caputo Nunes, Samara Costa Tavares, Heloísa Vicente Garcia, Maira Smaniotto Cucielo, Sérgio Alexandre Alcântara dos Santos, et al.
Environmental Toxicology, 2022
Prostate Cancer Secretome and Membrane Proteome from Pten Conditional Knockout Mice Identify Potential Biomarkers for Disease Progression
Nilton J. Santos, Ana Carolina Lima Camargo, Hernandes F. Carvalho, Luis Antonio Justulin, Sérgio Luis Felisbino
International Journal of Molecular Sciences, 2022
Maternal Low-Protein Diet Deregulates DNA Repair and DNA Replication Pathways in Female Offspring Mammary Gland Leading to Increased Chemically Induced Rat Carcinogenesis in Adulthood
Joyce R. Zapaterini, Antonio R. B. Fonseca, Lucas T. Bidinotto, Ketlin T. Colombelli, André L. D. Rossi, et al.
Frontiers in Cell and Developmental Biology, 2022
THE ROUND LIGAMENT IN DEVELOPMENTAL HIP DYSPLASIA: ARE ITS MECHANICAL AND HISTOLOGICAL PROPERTIES PRESERVED?
ALEXANDRE ZUCCON, HAMILTON DA ROSA PEREIRA, SÉRGIO ALEXANDRE ALCÂNTARA DOS SANTOS, SÉRGIO LUÍS FELISBINO, LUÍS ANTÔNIO JUSTULIN JUNIOR, et al.
Acta Ortopedica Brasileira, 2022
Effect of organic and inorganic zinc supplementation on the development of mandibular glands in apis mellifera
Bulletin of Insectology, 2021
Prediction of Non-canonical Routes for SARS-CoV-2 Infection in Human Placenta Cells
Flávia Bessi Constantino, Sarah Santiloni Cury, Celia Regina Nogueira, Robson Francisco Carvalho, Luis Antonio Justulin
Frontiers in Molecular Biosciences, 2021
Exposure to bacteriophages t4 and m13 increases integrin gene expression and impairs migration of human pc-3 prostate cancer cells
Swapnil Ganesh Sanmukh, Nilton J. Santos, Caroline Nascimento Barquilha, Sérgio Alexandre Alcantara dos Santos, Bruno Oliveira Silva Duran, et al.
Antibiotics, 2021
Transcriptomic landscape of male and female reproductive cancers: Similar pathways and molecular signatures predicting response to endocrine therapy
Ana CL. Camargo, Beatriz Remoli, Luiz MF. Portela, Mateus N. Fioretto, Luiz GA. Chuffa, et al.
Molecular and Cellular Endocrinology, 2021
Preventive training does not interfere with mRNA-encoding myosin and collagen expression during pulmonary arterial hypertension
Thaoan Bruno Mariano, Anthony César de Souza Castilho, Ana Karenina Dias de Almeida Sabela, André Casanova de Oliveira, Sarah Santiloni Cury, et al.
Plos One, 2021
Syndecan Family Gene and Protein Expression and Their Prognostic Values for Prostate Cancer
Nilton José Santos, Caroline Nascimento Barquilha, Isabela Correa Barbosa, Rodrigo Tavares Macedo, Flávio Oliveira Lima, et al.
International Journal of Molecular Sciences, 2021
Maternal protein restriction changes structural and metabolic gene expression in the skeletal muscle of aging offspring rats
Histology and Histopathology, 2021
The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity
Gabriela Bueno, Stefanni Liliane Chavez Rico, Larissa Lucena Périco, Rie Ohara, Vinicius Peixoto Rodrigues, et al.
Journal of Ethnopharmacology, 2021
Increased oxidative stress and cancer biomarkers in the ventral prostate of older rats submitted to maternal malnutrition
Luiz MF. Portela, Sérgio AA. Santos, Flavia B. Constantino, Ana CL. Camargo, Ketlin T. Colombelli, et al.
Molecular and Cellular Endocrinology, 2021
Protein feed stimulates the development of mandibular glands of honey bees (Apis mellifera)
Marcelo P Camilli, Daniel C B de Barros, Luis A Justulin, Marcos L P Tse, Ricardo de Oliveira Orsi
Journal of Apicultural Research, 2021
Mineral iron affects the development of mandibular gland in Apis mellifera
Daniel C. B. de Barros, Alex Junji Shinohara, Marcelo P. Camilli, Sérgio A. A. Santos, Luis A. Justulin, et al.
Journal of Apicultural Research, 2021
Maternal protein restriction impairs nutrition and ovarian histomorphometry without changing p38MAPK and PI3K-AKT-mTOR signaling in adult rat ovaries
Lucas Silva Côrtes, Henrique Spaulonci Silveira, Luiz Antonio Lupi, Talita de Mello Santos, Marilia Martins Cavariani, et al.
Life Sciences, 2021
A meta-analysis of microRNA networks regulated by melatonin in cancer: Portrait of potential candidates for breast cancer treatment
Luiz Gustavo de Almeida Chuffa, Robson Francisco Carvalho, Luis Antônio Justulin, Sarah Santiloni Cury, Fábio Rodrigues Ferreira Seiva, et al.
Journal of Pineal Research, 2020
Panax ginseng metabolite (GIM-1) modulates the effects of monobutyl phthalate (MBP) on the GPR30/GPER1 canonical pathway in human Sertoli cells
André Teves A.G. de Freitas, Cristiane Figueiredo Pinho, Ariana Musa Aquino, Raquel Fantin Domeniconi, Luis Antonio Justulin, et al.
Reproductive Toxicology, 2020
Terminalia catappa L. infusion accelerates the healing process of gastric ischemia-reperfusion injury in rats
Rie Ohara, Larissa Lucena Périco, Vinicius Peixoto Rodrigues, Gabriela Bueno, Ana Caroline Zanatta, et al.
Journal of Ethnopharmacology, 2020
Highly effective fibrin biopolymer scaffold for stem cells upgrading bone regeneration
Camila Fernanda Zorzella Creste, Patrícia Rodrigues Orsi, Fernanda Cruz Landim-Alvarenga, Luis Antônio Justulin, Marjorie de Assis Golim, et al.
Materials, 2020
Seasonal variation of flavonoid content in bee bread: Potential impact on hypopharyngeal gland development in Apis mellifera honey bees
Thaís de Souza Bovi, André Caeiro, Sérgio Alexandre Alcantara dos Santos, Rodrigo Zaluski, Alex Junji Shinohara, et al.
Journal of Apicultural Research, 2020
Chapter 20: Nutrition and prostate cancer prevention
L. A. Justulin, S. A. A. dos Santos, D. C. Damasceno, W. R. Scarano, S. L. Felisbino
Food Chemistry Function and Analysis, 2020
Sulfiredoxin as a Potential Therapeutic Target for Advanced and Metastatic Prostate Cancer
Caroline N. Barquilha, Nilton J. Santos, Caio C. D. Monção, Isabela C. Barbosa, Flávio O. Lima, et al.
Oxidative Medicine and Cellular Longevity, 2020
Identification of potential molecular pathways involved in prostate carcinogenesis in offspring exposed to maternal malnutrition
Sérgio Alexandre Alcantara Santos, Ana Carolina Lima Camargo, Flávia Bessi Constantino, Ketlin Thassiani Colombelli, Luiz Marcos Frediani Portela, et al.
Aging, 2020
“Prostate telocytes change their phenotype in response to castration or testosterone replacement”
Sérgio Luis Felisbino, Bruno Domingos Azevedo Sanches, Flávia Karina Delella, Wellerson Rodrigo Scarano, Fernanda Cristina Alcântara Dos Santos, et al.
Scientific Reports, 2019
Impact of gestational low protein diet and postnatal bisphenol A exposure on chemically induced mammary carcinogenesis in female offspring rats
Muriele B. Varuzza, Joyce R. Zapaterini, Ketlin T. Colombelli, Caroline N. Barquilha, Luis A. Justulin, et al.
Environmental Toxicology, 2019
Arsenic exposure during prepuberty alters prostate maturation in pubescent rats
Ariana M. Aquino, Giovanna C. Salata, Cristiane F. Pinho, André T.A.G. de Freitas, Larissa L. Périco, et al.
Reproductive Toxicology, 2019
Exposure to an Environmentally Relevant Phthalate Mixture during Prostate Development Induces MicroRNA Upregulation and Transcriptome Modulation in Rats
Wellerson R Scarano, Amina Bedrat, Luiz G Alonso-Costa, Ariana M Aquino, Bruno E A Fantinatti, et al.
Toxicological Sciences, 2019
Raloxifene decreases cell viability and migratory potential in prostate cancer cells (LNCaP) with GPR30/GPER1 involvement
Giovanna Cassone Salata, Cristiane Figueiredo Pinho, André T A G de Freitas, Ariana Musa Aquino, Luis Antonio Justulin, et al.
Journal of Pharmacy and Pharmacology, 2019
Panax ginseng methabolit (GIM-1) prevents oxidative stress and apoptosis in human Sertoli cells exposed to Monobutyl-phthalate (MBP)
André Teves A.G. DE FREITAS, Cristiane Figueiredo PINHO, Ariana Musa de AQUINO, Ana Angélica H. FERNANDES, Raquel Fantin DOMENICONI, et al.
Reproductive Toxicology, 2019
Maternal low-protein diet impairs prostate growth in young rat offspring and induces prostate carcinogenesis with aging
Sergio A A Santos, Ana C Camargo, Flávia B Constantino, Ketlin T Colombelli, Fernanda Mani, et al.
Journals of Gerontology Series A Biological Sciences and Medical Sciences, 2019
Protective effect of resveratrol on urogenital sinus and prostate development in rats exposed in utero to TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin)
Lívia Teresa Ribeiro Silveira, Talita de Mello Santos, Lucas Fredini Camora, Cristiane Figueiredo Pinho, Janete A. Anselmo-Franci, et al.
Reproductive Toxicology, 2019
Fibrin biopolymer as scaffold candidate to treat bone defects in rats
Claudia Vilalva Cassaro, Luis Antonio Justulin Jr., Patrícia Rodrigues de Lima, Marjorie de Assis Golim, Natália Perussi Biscola, et al.
Journal of Venomous Animals and Toxins Including Tropical Diseases, 2019
Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats
Larissa Lucena Périco, Vinícius Peixoto Rodrigues, Rie Ohara, Gabriela Bueno, Vânia Vasti Alfieri Nunes, et al.
World Journal of Gastroenterology, 2018
Maternal protein malnutrition: Effects on prostate development and adult disease
J. C. Rinaldi, S. A. A. Santos, K. T. Colombelli, L. Birch, G. S. Prins, et al.
Journal of Developmental Origins of Health and Disease, 2018
Evaluation of collagen in dermal wounds of rabbits treated with different sources of platelet-rich plasma
E. Ferraciolli, C.B. Laposy, M.R. Nogueira, L.A. Justulin Júnior, J.C. Camargo Filho, et al.
Arquivo Brasileiro De Medicina Veterinaria E Zootecnia, 2018
Combinatorial Effect of Abiraterone Acetate and NVP-BEZ235 on Prostate Tumor Progression in Rats
Bianca Facchim Gonçalves, Silvana Gisele Pegorin de Campos, Wagner José Fávaro, Joyce Zalotti Brandt, Cristiane Figueiredo Pinho, et al.
Hormones and Cancer, 2018
Influence of postnatal prolactin modulation on the development and maturation of ventral prostate in young rats
Ana C. L. Camargo, Flávia B. Constantino, Sérgio A. A. Santos, Ketlin T. Colombelli, Maeli Dal-Pai-Silva, et al.
Reproduction Fertility and Development, 2018
Hyperglycemic condition during puberty increases collagen fibers deposition in the prostatic stroma and reduces MMP-2 activity
Sérgio Alexandre Alcantara dos Santos, Elaine Manoela Porto Amorim, Larissa Mayume Ribeiro, Jaqueline Carvalho Rinaldi, Flávia Karina Delella, et al.
Biochemical and Biophysical Research Communications, 2017
Field-relevant doses of the systemic insecticide fipronil and fungicide pyraclostrobin impair mandibular and hypopharyngeal glands in nurse honeybees (Apis mellifera)
Rodrigo Zaluski, Luis Antonio Justulin, Ricardo de Oliveira Orsi
Scientific Reports, 2017
Apitoxin harvest impairs hypopharyngeal gland structure in Apis mellifera honey bees
Thaís S. Bovi, Paula Onari, Sérgio A. A. Santos, Luis A. Justulin, Ricardo O. Orsi
Apidologie, 2017
The prostate response to prolactin modulation in adult castrated rats subjected to testosterone replacement
Flávia B. Constantino, Ana C. L. Camargo, Sérgio A. A. Santos, Ketlin T. Colombelli, Laura F. Martin, et al.
Journal of Molecular Histology, 2017
Impact of maternal and postnatal zinc dietary status on the prostate of pubescent and adult rats
Lucas F. Camora, Ana Priscila G. Silva, Sérgio A.A. Santos, Luis A. Justulin, Juliana E. Perobelli, et al.
Cell Biology International, 2017
A unique heterologous fibrin sealant (HFS) as a candidate biological scaffold for mesenchymal stem cells in osteoporotic rats
Patrícia Rodrigues Orsi, Fernanda Cruz Landim-Alvarenga, Luis Antônio Justulin, Ramon Kaneno, Marjorie de Assis Golim, et al.
Stem Cell Research and Therapy, 2017
Impairment of microvascular angiogenesis is associated with delay in prostatic development in rat offspring of maternal protein malnutrition
Ketlin T. Colombelli, Sérgio A.A. Santos, Ana C.L. Camargo, Flávia B. Constantino, Caroline N. Barquilha, et al.
General and Comparative Endocrinology, 2017
Streptozotocin-Induced Maternal Hyperglycemia Increases the Expression of Antioxidant Enzymes and Mast Cell Number in Offspring Rat Ventral Prostate
Ana C. L. Camargo, Sérgio A. A. Dos Santos, Jaqueline C. Rinaldi, Flavia B. Constantino, Ketlin T. Colombelli, et al.
Anatomical Record, 2017
Collagen quantification in rabbit dermal wounds treated with heterologous platelet-rich plasma gel
Maria Elisa Marin Marques, Cecília Braga Laposy, Mariana Lucas Dos Santos Silva, Maria Rosa Santos Breda, Mayara Mascaro Matsumoto, et al.
Semina Ciencias Agrarias, 2017
Effects of intra-articular injection of mesenchymal stem cells associated with platelet-rich plasma in a rabbit model of osteoarthritis
L.C. Hermeto, R. DeRossi, R.J. Oliveira, J.R. Pesarini, A.C.M.B. Antoniolli-Silva, et al.
Genetics and Molecular Research, 2016
Comparison between two different experimental model of osteoarthritis in rabbits. Intra-articular collagenase injection and anterior cruciate ligament transection
Larissa Correa Hermeto, Rafael De Rossi, Paulo Henrique de Affonseca Jardim, Aureo Evangelista Santana, Jaqueline de Carvalho Rinaldi, et al.
Acta Cirurgica Brasileira, 2016
Long-term effects of perinatal exposure to low doses of cadmium on the prostate of adult male rats
Viviane P. Santana, Évila S. Salles, Deborah E. Correa, Bianca F. Gonçalves, Silvana G. Campos, et al.
International Journal of Experimental Pathology, 2016
Ethanol modulates the synthesis and catabolism of retinoic acid in the rat prostate
Beatriz Aparecida Fioruci-Fontanelli, Luiz Gustavo A. Chuffa, Leonardo O. Mendes, Patricia Fernanda F. Pinheiro, Luis Antônio Justulin, et al.
Reproductive Toxicology, 2015
Cadmium exposure inhibits MMP2 and MMP9 activities in the prostate and testis
Livia M. Lacorte, Jaqueline C. Rinaldi, Luis A. Justulin, Flávia K. Delella, Andrei Moroz, et al.
Biochemical and Biophysical Research Communications, 2015
Impact of gestational diabetes and lactational insulin replacement on structure and secretory function of offspring rat ventral prostate
Sérgio A.A. Santos, Jaqueline C. Rinaldi, Amanda E. Martins, Ana C.L. Camargo, Carina Leonelli, et al.
General and Comparative Endocrinology, 2014
Protective effect of γ-tocopherol-enriched diet on N-methyl-N-nitrosourea-induced epithelial dysplasia in rat ventral prostate
Lucas D. Sanches, Sergio A. A. Santos, Jaqueline R. Carvalho, Gabriela D. M. Jeronimo, Wagner J. Favaro, et al.
International Journal of Experimental Pathology, 2013
Implications of intrauterine protein malnutrition on prostate growth, maturation and aging
Jaqueline C. Rinaldi, Luis A. Justulin, Livia M. Lacorte, Carolina Sarobo, Patricia A. Boer, et al.
Life Sciences, 2013
Structural and ultrastructural evidence for telocytes in prostate stroma
Lara S. Corradi, Mariana M. Jesus, Ricardo A. Fochi, Patricia S. L. Vilamaior, Luis A. Justulin‐, et al.
Journal of Cellular and Molecular Medicine, 2013
Mechanism and effect of esculetin in an experimental animal model of inflammatory bowel disease
A. Witaicenis, A.C. Luchini, C.A. Hiruma-Lima, S.L. Felisbino, L.A. Justulin, et al.
European Journal of Inflammation, 2013
MMP-2 and TIMP-2 in the prostates of male and female mongolian gerbils: Effects of hormonal manipulation
Histology and Histopathology, 2011
Long-term high-fat diet-induced obesity decreases the cardiac leptin receptor without apparent lipotoxicity
André F. Nascimento, Renata A.M. Luvizotto, André S. Leopoldo, Ana P. Lima-Leopoldo, Fábio R. Seiva, et al.
Life Sciences, 2011
Exposure to Mycobacterium avium Decreases the Protective Effect of the DNA Vaccine pVAXhsp65 Against Mycobacterium tuberculosis-Induced Inflammation of the Pulmonary Parenchyma
D. R. Martins, A. C. Pelizon, S. F. G. Zorzella‐Pezavento, J. Seger, R. R. Santos Junior, et al.
Scandinavian Journal of Immunology, 2011
Lobe variation effects of experimental diabetes and insulin replacement on rat prostate
Elaine Manoela Porto, Sérgio Alexandre De Alcântara Dos Santos, Larissa Mayumi Ribeiro, Lívia Maria Lacorte, Jaqueline Carvalho Rinaldi, et al.
Microscopy Research and Technique, 2011
Microscopical evaluation of extracellular matrix and its relation to the palatopharyngeal muscle in obstructive sleep apnea
Fernando D. Molina, Fernanda C.A. Santos, Luis R. Falleiros, Eny M. Goloni‐Bertollo, Sérgio L. Felisbino, et al.
Microscopy Research and Technique, 2011
Early changes induced by short-term low-dose cadmium exposure in rat ventral and dorsolateral prostates
Lívia M. Lacorte, Flavia K. Delella, Elaine M. Porto Amorim, Luis A. Justulin, Antonio F. Godinho, et al.
Microscopy Research and Technique, 2011
MMP-2 and MMP-9 localization and activity in the female prostate during estrous cycle
Fernanda C.A. Santos, Sabrina S. Rochel-Maia, Ricardo A. Fochi, Luis A. Justulin, Sérgio A.A. Santos, et al.
General and Comparative Endocrinology, 2011
Matrix metalloproteinase (MMP)-2 and MMP-9 activity and localization during ventral prostate atrophy and regrowth
L. A. Justulin Jr, H. H. M. Della‐Coleta, S. R. Taboga, S. L. Felisbino
International Journal of Andrology, 2010
Combined effect of the finasteride and doxazosin on rat ventral prostate morphology and physiology
Luis A. Justulin Jr, Carolina Acquaro, Robson F. Carvalho, Maeli Dal Pai Silva, Sérgio L. Felisbino
International Journal of Andrology, 2010
Finasteride treatment alters MMP-2 and -9 gene expression and activity in the rat ventral prostate
Flávia K. Delella, Luis A. Justulin Jr, Sérgio L. Felisbino
International Journal of Andrology, 2010
Neonatal BCG immunization followed by dnahsp65 boosters: Highly immunogenic but not protective against tuberculosis-a paradoxical effect of the vector?
A. C. Pelizon, D. R. Martins, S. F. G. Zorzella-Pezavento, J. Seger, L. A. Justulin Jr, et al.
Scandinavian Journal of Immunology, 2010
Tissue vitamin A insufficiency results in adverse ventricular remodeling after experimental myocardial infarction
Marcos F. Minicucci, Paula S. Azevedo, Silvio A. Oliveira Jr., Paula F. Martinez, Fernanda Chiuso-Minicucci, et al.
Cellular Physiology and Biochemistry, 2010
Ventricular remodeling induced by tissue vitamin A deficiency in rats
Paula S. Azevedo, Marcos F. Minicucci, Fernanda Chiuso-Minicucci, Luis A. Justulin Jr, Luiz S. Matsubara, et al.
Cellular Physiology and Biochemistry, 2010
Calcaneal tendon regions exhibit different MMP-2 activation after vertical jumping and treadmill running
Olga Cristina De Mello Malheiro, Camila Tateishi Giacomini, Luis Antonio Justulin, Flávia Karina Delella, Maeli Dal‐Pai‐Silva, et al.
Anatomical Record, 2009
Long-term effects of developmental exposure to di-n-butyl-phthalate (DBP) on rat prostate: Proliferative and inflammatory disorders and a possible role of androgens
Wellerson Rodrigo Scarano, Fabíola Choqueta de Toledo, Marina Trevizan Guerra, Silvana Gisele Pegorin de Campos, Luís Antonio Justulin Júnior, et al.
Toxicology, 2009
Effect of mangiferin on the development of periodontal disease: Involvement of lipoxin A4, anti-chemotaxic action in leukocyte rolling
Roney Rick Carvalho, Claudia Helena Pellizzon, Luis Justulin, Sergio Luis Felisbino, Wagner Vilegas, et al.
Chemico Biological Interactions, 2009
Differential MMP-2 and MMP-9 activity and collagen distribution in skeletal muscle from pacu (Piaractus mesopotamicus) during juvenile and adult growth phases
Aline Cristina Michelin, Luis Antonio Justulin, Flávia Karina Delella, Carlos Roberto Padovani, Sérgio Luis Felisbino, et al.
Anatomical Record, 2009
Metalloproteinases 2 and -9 activity during promotion and progression stages of rat liver carcinogenesis
Kelly Silva Furtado, Paulo Wagner Pires, Luis Antonio Justulin, Maria Aparecida Marchesan Rodrigues, Sergio Luis Felisbino, et al.
Journal of Molecular Histology, 2009
Evaluation of matrix metalloproteinases -2 and -9 in cats under bone demineralization secondary to induced thyrotoxicosis
F.S. Costa, M.J.L. Cardoso, L.M.R. Muniz, L.C. Vulcano, L.A. Justulin Júnior, et al.
Arquivo Brasileiro De Medicina Veterinaria E Zootecnia, 2008
Immunolocalization of aquaporins 1, 2 and 7 in rete testis, efferent ducts, epididymis and vas deferens of adult dog
Raquel Fantin Domeniconi, Antonio Marcos Orsi, Luis Antonio Justulin, Célia Cristina Leme Beu, Sérgio Luis Felisbino
Cell and Tissue Research, 2008
Doxazosin reduces cell proliferation and increases collagen fibers in rat prostatic lobes
Luis A. Justulin, Flavia K. Delella, Sérgio L. Felisbino
Cell and Tissue Research, 2008
Aquaporin 9 (AQP9) localization in the adult dog testis excurrent ducts by immunohistochemistry
Raquel Fantin Domeniconi, Antonio Marcos Orsi, Luis Antonio Justulin, Célia Cristina Leme Beu, Sérgio Luis Felisbino
Anatomical Record, 2007
Epithelial-stromal transition of MMP-7 immunolocalization in the rat ventral prostate following bilateral orchiectomy
Sergio L. Felisbino, Luis A. Justulin Junior, Hernandes F. Carvalho, Sebastião R. Taboga
Cell Biology International, 2007
Tissue inhibitor of metalloproteinase-2 (TIMP-2) location in the ventral, lateral, dorsal and anterior lobes of rat prostate by immunohistochemistry
Flávia K. Delella, Luis A. Justulin, Sérgio L. Felisbino
Cell Biology International, 2007
Heart failure alters matrix metalloproteinase gene expression and activity in rat skeletal muscle
Robson Francisco Carvalho, Rafael Dariolli, Luis Antonio Justulin Junior, Mário Mateus Sugizaki, Marina Politi Okoshi, et al.
International Journal of Experimental Pathology, 2006
Differential proliferative response of the ventral prostate and seminal vesicle to testosterone replacement
Luis A. Justulin, Rodrigo P. Ureshino, Michelle Zanoni, Sergio L. Felisbino
Cell Biology International, 2006

Luis Antonio Justulin Jr

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