Development of novel electroactive material for the construction of biosensor platform
30
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622
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14
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18
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Scopus Publications
Structure-optimized truncated aptamers coupled with copper tungstate–reduced graphene oxide for multiplexed electrochemical biosensing of chlorpyrifos, diazinon, and malathion Asma Zaid Almenhali, Pandiyaraj Kanagavalli, Walid A. M. Elgaher, Marwa Abd-Ellah, Shimaa Eissa Advanced Composites and Hybrid Materials, 2026 Organophosphorus pesticides such as chlorpyrifos, diazinon, and malathion are major environmental contaminants that require continuous monitoring. In this work, a multiplex electrochemical aptasensor was developed for the simultaneous detection of these pesticides using structure-optimized truncated aptamers. Truncation designs of the aptamers were rationally developed based on Mfold-predicted secondary structures to enhance binding performance. The designed truncations were experimentally evaluated through electrochemical binding studies and further validated using molecular docking to identify the optimum binding aptamer sequences. A copper tungstate (CuWO₄)/reduced graphene oxide (rGO) nanocomposite was synthesized and integrated into the multiplexed electrochemical aptasensor platform. Three CuWO₄ synthesis methods were investigated and optimized with different CuWO₄-to-rGO ratios using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The citric acid-assisted hydrothermal CuWO₄ showed the highest electrochemical performance, particularly at a CuWO₄-to-rGO ratio of 2:1, due to the synergistic enhancement of electrochemical performance compared to rGO alone. The developed aptasensor exhibited excellent analytical performance, with linear detection ranges of 10 pM–100 nM for Chlor-T4 and Mala-T2, and 10 pM–10 µM for Diaz-T1. The platform demonstrated excellent selectivity and high sensitivity, achieving low limits of detection (LODs) of 60.5 pM, 23.9 pM, and 73.0 pM for chlorpyrifos, diazinon, and malathion, respectively. Validation using spiked tomato, strawberry, and water samples confirmed the practical applicability of the developed platform for real-time and on-site detection. This work highlights the effectiveness of structure-optimized truncated aptamers integrated with CuWO₄/rGO-based nanocomposites for advanced multiplexed detection of environmental pollutants and contributes to the development of next-generation biosensing technologies for environmental monitoring.
Reduced graphene oxide-based electrochemical aptasensor for the multiplexed detection of imidacloprid, thiamethoxam, and clothianidin in food samples Asma Zaid Almenhali, Pandiyaraj Kanagavalli, Marwa Abd-Ellah, Salma Khazaal, Nada El Darra, Shimaa Eissa Scientific Reports, 2025 Neonicotinoids are a group of neurotoxic insecticides that possess significant threats not only to the environment but also to human health. This underlines the importance of developing efficient and accurate tools to detect neonicotinoids and track their behavior. Aptamers have been widely used as stable, efficient, and specific biorecognition molecules in biosensors. Nonetheless, no aptasensor was reported for the multiplexed detection of neonicotinoids. Herein, a graphene-based electrochemical biosensor was fabricated with three aptamers for the detection of imidacloprid, thiamethoxam, and clothianidin. The imidacloprid-specific aptamer underwent a truncation, which showed strong affinity with K D = 12.8 nM compared to 20.1 nM of the original sequence when studied with differential pulse voltammetry (DPV). Screen printed electrodes were coated with graphene oxide. After electrochemical reduction, 1-pyrenebutyric acid was used to functionalize the electrodes and covalently immobilize the aptamers. The electrodes were characterized by scanning electron microscopy (SEM), Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS) to ensure successful aptasensor fabrication. The biosensor displayed excellent sensitivity compared with reported aptasensors and linear ranges from 0.01 ng/mL to 100 ng/mL for imidacloprid, thiamethoxam, and clothianidin. It also demonstrated excellent selectivity to the three analytes. Spiked extracts from tomato and rice samples were analyzed using our aptasensor, and results were validated through conventional chromatography assays. High recovery rates for all three neonicotinoids were obtained, demonstrating excellent agreement between the two methods. This study presents a cost-effective and simple multiplex detection for the sensitive, specific, and accurate on-site analysis of neonicotinoids.
Electrochemical sensor for the detection of imidacloprid using novel Cu-tetrazole MOF Joseph Joe Habr, Fatima El Alem, Pandiaraj Kanagavalli, Upendar Reddy Gandra, Anish Mathai Varghese, Hassan Saraierh, Ibrahim Yildiz, Ayalew H. Assen, Gareth Price, Shimaa Eissa, M․ Infas H․ Mohideen Sensors and Actuators Reports, 2025 Designing sensitive and rapid sensing platforms for detecting pesticide residues is crucial for ensuring environmental and food safety. In this work, we report the synthesis of a novel Cu-Tetrazole Metal-Organic Framework referred to as KU-1 and its utilization for the development of an electrochemical sensor for the detection of imidacloprid (IMD) residues in food samples. The MOF structure consists of Cu ions and tetrazole ligands that extend to form 2D layers, which are further pillared by tetrazoles to create a 3D network. The KU-1 exhibits high stability, retaining crystallinity in various organic solvents and a range of pH, with thermal stability up to ∼300°C. The electrochemical sensing of IMD at KU-1 modified screen-printed electrode was investigated in detail, demonstrating the material's high electrocatalytic performance. The developed sensor allowed imidacloprid detection in the linear range of 0.1–10 μM with a detection limit of 0.089 μM and showed excellent selectivity for IMD against other pesticides. Detection of IMD residues was successfully validated in rice and tomato sample extracts and had a remarkable recovery of 97–101%, showcasing the electrode's practicality and reliability. This study highlights the potential of KU-1 as a promising material for constructing high-performance electrochemical sensors.
Electrochemical truncated aptasensors for dual detection of enrofloxacin and ofloxacin using in-situ deposited reduced graphene oxide/gold nanoparticle composite Pandiaraj Kanagavalli, Abdullah Al Ameri, Shimaa Eissa Environmental Technology and Innovation, 2025 Monitoring fluoroquinolones (FQs), such as enrofloxacin (ENO) and ofloxacin (OFL), commonly used antibiotics, is vital for food and environmental safety. This study presents a novel electrochemical aptasensor for the simultaneous detection of ENO and OFL. Truncated DNA aptamers were designed and tested, showing improved binding affinity ( K d values of 20.6 nM for OFL and 7.9 nM for ENO). First, a composite of in-situ reduced graphene oxide (rGO) and gold nanoparticles (AuNPs) was electrodeposited onto the carbon screen-printed electrodes (rGO/AuNPs/SPE). Morphological and structural analysis of the rGO/AuNPs/SPE was conducted using scanning electron microscopy and X-ray photoelectron microscopy after electrodeposition. The truncated aptamer with the lowest K d was immobilized on the rGO/AuNPs/SPE surface, and the remaining sites were blocked with Mercaptohexanol to enable selective analyte recognition. The constructed multiplexed aptasensor exhibited linear detection ranges from 0.001 to 100 ng/mL for OFL and ENO, with limits of detection of 0.17 pg/mL for OFL and 1.3 pg/mL for ENO, respectively. The dual aptasensor showed excellent selectivity against common interferents, and high recovery rates in spiked milk, tap water, and wastewater samples ranged from 95 to 108 %. This study highlights the truncated aptasensor potential for rapid, on-site detection of fluoroquinolone antibiotics in complex matrices, addressing critical needs in food safety and environmental monitoring. • New truncated aptamers were designed to enhance the binding affinity for OFL and ENO. • A dual electrochemical aptasensor was developed using in-situ electrodeposited rGO/AuNPs. • The aptasensor enabled simultaneous and selective detection of OFL and ENO • The platform demonstrated excellent analytical performance in water and milk samples.
Ultrasensitive electrochemical biosensor for the simultaneous detection of the two monkeypox virus antigens M1R and A29 using reduced graphene oxide-ZIF-8 nanocomposite Pandiaraj Kanagavalli, Ragi Adham Elkaffas, Shimaa Eissa Chemical Engineering Journal, 2025 • A novel electrochemical immunosensor was engineered for the simultaneous and selective detection of MPXV proteins M1R and A29. • Three morphologically distinct GO/ZIF-8 composites were synthesized, characterized, and evaluated for their electrochemical performance for the first time. • rGO/ZIF-8 nanoparticles were established as the optimal biosensing platform, enabling efficient antibody immobilization and signal transduction. • The immunosensor achieved ultrasensitive detection limits of 3.4 pg/mL for M1R and 5.1 pg/mL for A29, demonstrating its potential for clinical and environmental monitoring applications. Monkeypox virus (MPXV) has become a public health emergency of international concern, and its transmission occurs through respiratory droplets, direct contact with skin lesions, fomites, and sexual contact. However, there are no widely accessible diagnostic tests for MPXV in decentralized settings. Here, a novel electrochemical biosensor is presented for the simultaneous detection of MPXV proteins, M1R, and A29. Nanocomposites of graphene oxide and Zeolitic Imidazolate Framework-8 (ZIF-8) with three different morphological structures were synthesized and characterized using scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. The composites were deposited onto dual-carbon screen-printed electrodes (SPEs) and electrochemically reduced to form reduced graphene oxide-ZIF-8/SPE (rGO-ZIF-8/SPE). Monoclonal antibodies targeting the A29 and M1R antigens of the MPXV were immobilized on the rGO-ZIF-8/SPE to develop a multiplexed immunosensor. Detection was performed using differential pulse voltammetry, demonstrating excellent sensitivity for MPXV antigens within a dynamic range of 1 pg/mL to 10 µg/mL, with detection limits of 5.1 pg/mL for A29 and 3.4 pg/mL for M1R. The biosensor demonstrated high sensitivity and selectivity, with no cross-reactivity to other respiratory virus antigens, making it ideal for point-of-care MPXV testing. The electrochemical immunosensor was tested in spiked serum samples, and the results were compared to commercial ELISA kits, showing high recovery percentages ranging from 90 to 104 %. The dual electrochemical biosensing platform also offers excellent reproducibility and scalability, making it suitable for frequent, decentralized use.
SELEX-derived DNA aptamer utilized for sensitive electrochemical biosensing of Toxoplasma gondii surface antigen 1 Pandiyaraj Kanagavalli, Shahad Alkhaldi, Mohammed Zourob, Shimaa Eissa International Journal of Biological Macromolecules, 2025 Toxoplasma gondii ( T. gondii ) is a global parasitic pathogen with significant health implications. Effective diagnosis is crucial, especially for vulnerable populations like immunocompromised individuals and pregnant women. Here, we developed a novel electrochemical aptasensor for detecting Surface Antigen 1 (SAG1), a key biomarker for acute T. gondii infections. New high-affinity aptamers (SOK3, SOK14, and SOK18) specific to SAG1 were identified using SELEX method. The aptamers were then immobilized onto screen-printed carbon electrodes (SPE) modified with graphene quantum dots (GQDs). Physicochemical characterization confirmed successful aptasensor fabrication. SOK14 was identified as optimal for SAG1 detection due to its lower dissociation constant and distinct current response upon protein binding. Square wave voltammetry (SWV) showed a linear response from 0.01 to 100 nM SAG1 ( n = 3), correlating with [Fe(CN) 6 ] 3−/4− oxidation peak current changes and achieving a low detection limit of 11.5 pM with relative standard deviations ranging from 3.3 to 4.9 %. Selectivity studies against other nonspecific biomarkers for other pathogens validated the aptasensor's specificity. Application of the aptasensor in spiked serum samples indicated its efficiency in complex biological samples. This platform enables rapid, on-site detection of T. gondii with high sensitivity, selectivity, and reliability in serum samples, supporting early diagnosis and timely treatment to prevent complications.
Electrochemical immunosensor for the predictive cancer biomarker SLFN11 using reduced graphene oxide/MIL-101(Cr)-NH2 composite Pandiyaraj Kanagavalli, Ragi Adham Elkaffas, M. Infas H. Mohideen, Shimaa Eissa International Journal of Biological Macromolecules, 2025 SLFN11 is a predictive cancer biomarker essential for identifying tumors that are sensitive to DNA-damaging agents, facilitating more personalized and effective treatment approaches. Detecting this biomarker can guide therapeutic decisions and improve outcomes for cancer patients. However, existing detection methods for SLFN11 are complex and require advanced techniques. In this study, we introduce the first immunosensor designed for on-site detection of SLFN11. An advanced electrochemical immunosensor platform utilizing a composite of graphene oxide (GO) and chromium-based metal organic framework (MIL-101 (Cr)-NH 2 ) was developed. The integration of GO and MIL-101(Cr)-NH 2 was characterized through FT-IR, XRD, SEM, and XPS, affirming the formation of the composite. The subsequent electrochemical reduction to rGO/MIL-101(Cr)-NH 2 significantly improved the electrochemical performance and stability. A glutaraldehyde cross-linker was then utilized to attach the SLFN11-specific antibody to the amine groups of the MOF-modified electrodes. This led to the development of rapid, sensitive, portable, and cost-effective immunosensor for SLFN11 at concentrations as low as 8.9 pg/mL which holds promise for early cancer diagnosis. High specificity was achieved, with minimal cross-reactivity observed with other cancer biomarkers such as pepsinogen I, claudin 18.2 and Programmed cell death protein 1. Demonstrating practical applicability, the electrochemical immunosensor validated by commercial ELISA kit showed successful detection in serum samples with high recovery rates and reproducibility. This research highlights the potential of rGO/MOFs composites in electrochemical biosensors developments for early cancer diagnostics and personalized medicine.
Graphene oxide/Cu–MOF-based electrochemical immunosensor for the simultaneous detection of Mycoplasma pneumoniae and Legionella pneumophila antigens in water Kanagavalli Pandiyaraj, Ragi Adham Elkaffas, M. Infas H. Mohideen, Shimaa Eissa Scientific Reports, 2024 The combination of copper-metal organic framework (Cu-MOF) with graphene oxide (GO) has received growing interest in electrocatalysis, energy storage and sensing applications. However, its potential as an electrochemical biosensing platform remains largely unexplored. In this study, we introduce the synthesis of GO/Cu-MOF nanocomposite and its application in the simultaneous detection of two biomarkers associated with lower respiratory infections, marking the first instance of its use in this capacity. The physicochemical properties and structural elucidation of this composite were studied with the support of XRD, FTIR, SEM and electrochemical techniques. The immunosensor was fabricated by drop casting the nanocomposite on dual screen-printed electrodes followed by functionalization with pyrene linker. The covalent immobilization of the monoclonal antibodies of the bacterial antigens of Mycoplasma pneumoniae (M. pneumoniae; M. p.) and Legionella pneumophila (L. pneumophila; L. p.) was achieved using EDC-NHS chemistry. The differential pulse voltammetry (DPV) signals of the developed immunosensor platform demonstrated a robust correlation across a broad concentration range from 1 pg/mL to 100 ng/mL. The immunosensor platform has shown high degree of selectivity against antigens for various respiratory pathogens. Moreover, the dual immunosensor was successfully applied for the detection of M. pneumoniae and L. pneumophila antigens in spiked water samples showing excellent recovery percentages. We attribute the high sensitivity of the immunosensor to the enhanced electrocatalytic characteristics, stability and conductivity of the GO-MOF composite as well as the synergistic interactions between the GO and MOF. This immunosensor offers a swift analytical response, simplicity in fabrication and instrumentation, rendering it an appealing platform for the on-field monitoring of pathogens in environmental samples.
Exploring various carbon nanomaterials-based electrodes modified with polymelamine for the reagentless electrochemical immunosensing of Claudin18.2 Pandiyaraj Kanagavalli, Shimaa Eissa Biosensors and Bioelectronics, 2024 Claudin18.2 (CLDN18.2) is a tight junction protein often overexpressed in various solid tumors, including gastrointestinal and esophageal cancers, serving as a promising target and potential biomarker for tumor diagnosis, treatment assessment, and prognosis. Despite its significance, no biosensor has been reported to date for the detection of CLDN18.2. Here, we present the inaugural immunosensor for CLDN18.2. In this study, an amine-rich conducting polymer of polymelamine (PM) was electrografted onto different carbon nanomaterial-based screen-printed electrodes (SPEs), including carbon (C), graphene (Gr), graphene oxide (GO), carbon nanotube (CNT), and carbon nanofiber (CNF) via cyclic voltammetry. A comparative study was performed to explore the best material for the preparation of the PM-modified electrodes to be used as in-situ redox substrate for the immunosensor fabrication. The surface chemistry and structural features of pristine and PM-deposited electrodes were analyzed using Raman and scanning electron microscopy (SEM) techniques. Our results showed that the PM deposited on Gr and CNT/SPEs exhibited the most significant and stable redox behavior in PBS buffer. The terminal amine moieties on the PM-modified electrode surfaces were utilized for immobilizing anti-CLDN18.2 monoclonal antibodies via N-ethyl-N'-(3-(dimethylamino)propyl)carbodiimide/N-hydroxysuccinimide chemistry to construct the electrochemical immunosensor platform. Differential pulse voltammetry-based immunosensing of CLDN18.2 protein on BSA/anti-CLDN18.2/PM-Gr/SPE and BSA/anti-CLDN18.2/PM-CNT/SPE exhibited excellent selectivity against other proteins such as CD1, PDCD1, and ErBb2. The limits of detection of these two immunosensor platforms were calculated to be 7.9 pg/mL and 0.104 ng/mL for the CNT and Gr immunosensors, respectively. This study demonstrated that the PM-modified Gr and CNT electrodes offer promising platforms not only for the reagentless signaling but also for covalent immobilization of biomolecules. Moreover, these platforms offer excellent sensitivity and selectivity for the detection of CLDN18.2 due to its enhanced stable redox activity. The immunosensor demonstrated promising results for the sensitive detection of CLDN18.2 in biological samples, addressing the critical need for early gastric cancer diagnosis.
Label-free electrochemical immunoprobe for dengue infection marker detection Current Science, 2023
Fundamentals of a biosensor system Vinoth Krishnan, Gaurav Rajkumar Pandey, Kanagavalli Pandiyaraj Health and Environmental Applications of Biosensing Technologies Clinical and Allied Health Science Perspective, 2023
Structure-optimized truncated aptamers coupled with copper tungstate–reduced graphene oxide for multiplexed electrochemical biosensing of chlorpyrifos, diazinon, and malathion AZ Almenhali, P Kanagavalli, WAM Elgaher, M Abd-Ellah, S Eissa Advanced Composites and Hybrid Materials , 2026 2026
Electrochemical truncated aptasensors for dual detection of enrofloxacin and ofloxacin using in-situ deposited reduced graphene oxide/gold nanoparticle composite P Kanagavalli, A Al Ameri, S Eissa Environmental Technology & Innovation, 104635 , 2025 2025
Electrochemical sensor for the detection of imidacloprid using novel Cu-tetrazole MOF JJ Habr, F El Alem, P Kanagavalli, UR Gandra, AM Varghese, H Saraierh, ... Sensors and Actuators Reports, 100377 , 2025 2025 Citations: 8
Ultrasensitive electrochemical biosensor for the simultaneous detection of the two monkeypox virus antigens M1R and A29 using reduced graphene oxide-ZIF-8 nanocomposite P Kanagavalli, RA Elkaffas, S Eissa Chemical Engineering Journal 516, 164015 , 2025 2025 Citations: 8
SELEX-derived DNA aptamer utilized for sensitive electrochemical biosensing of Toxoplasma gondii surface antigen 1 P Kanagavalli, S Alkhaldi, M Zourob, S Eissa International Journal of Biological Macromolecules 310, 143530 , 2025 2025 Citations: 3
Reduced graphene oxide-based electrochemical aptasensor for the multiplexed detection of imidacloprid, thiamethoxam, and clothianidin in food samples AZ Almenhali, P Kanagavalli, M Abd-Ellah, S Khazaal, N El Darra, S Eissa Scientific Reports 15 (1), 10329 , 2025 2025 Citations: 23
Electrochemical immunosensor for the predictive cancer biomarker SLFN11 using reduced graphene oxide/MIL-101 (Cr)-NH2 composite P Kanagavalli, RA Elkaffas, MIH Mohideen, S Eissa International Journal of Biological Macromolecules 285, 138174 , 2025 2025 Citations: 12
Exploring various carbon nanomaterials-based electrodes modified with polymelamine for the reagentless electrochemical immunosensing of Claudin18. 2 P Kanagavalli, S Eissa Biosensors and Bioelectronics 259, 116388 , 2024 2024 Citations: 23
Graphene oxide/Cu–MOF-based electrochemical immunosensor for the simultaneous detection of Mycoplasma pneumoniae and Legionella pneumophila antigens in water K Pandiyaraj, RA Elkaffas, MIH Mohideen, S Eissa Scientific Reports 14 (1), 17172 , 2024 2024 Citations: 33
Redox probe-free electrochemical immunosensor utilizing electropolymerized melamine on reduced graphene oxide for the point-of-care diagnosis of gastric cancer P Kanagavalli, S Eissa Talanta 270, 125549 , 2024 2024 Citations: 12
Fundamentals of a biosensor system V Krishnan, GR Pandey, K Pandiyaraj Health and environmental applications of biosensing technologies, 1-25 , 2024 2024 Citations: 8
Label-free genosensing of dengue serotypes with an electrodeposited reduced graphene oxide-tris (bipyridine) ruthenium (II) P Kanagavalli, C Andrew, KA Babu, M Jayakumar, M Veerapandian International Journal of Biological Macromolecules 253, 126746 , 2023 2023 Citations: 1
Label-free electrochemical immunoprobe for dengue infection marker detection. P Kanagavalli, M Veerapandian Current Science (00113891) 125 (6) , 2023 2023
Electropolymerized melamine on electrochemically reduced graphene oxide: growth mechanistics, electrode processing, and amperometric sensing of acyclovir P Kanagavalli, M Natchimuthu Karuppusamy, VS Ganesan, ... Langmuir 39 (9), 3512-3525 , 2023 2023 Citations: 15
Electropolymerized methylene blue on graphene oxide framework for the direct voltammetric detection of gallic acid V Krishnan, E Gunasekaran, C Prabhakaran, P Kanagavalli, V Ananth, ... Materials Chemistry and Physics 295, 127071 , 2023 2023 Citations: 37
Molybdenum trioxide hybridized kaempferol: double-powered nanosystem for salvaging oxidative stress and electrochemical immunoprobing of interleukin-6 GR Pandey, P Kanagavalli, K Karnam, KT Arul, P Monisha, CL Dong, ... Materials Today Chemistry 24, 100809 , 2022 2022 Citations: 10
Electrochemical and DFT studies of andrographolide on electrochemically reduced graphene oxide for anti-viral herbaceutical sensor P Kanagavalli, GR Pandey, P Murugan, M Veerapandian Analytica Chimica Acta 1209, 339877 , 2022 2022 Citations: 9
In-situ redox-active hybrid graphene platform for label-free electrochemical biosensor: Insights from electrodeposition and electroless deposition P Kanagavalli, C Andrew, M Veerapandian, M Jayakumar TrAC Trends in Analytical Chemistry 143, 116413 , 2021 2021 Citations: 41
Synthesis of nanocubic shape controlled Gold-Prussian blue nanocomposite for enhanced electrocatalytic hydrazine oxidation P Kanagavalli, SS Kumar Journal of Electroanalytical Chemistry 897, 115566 , 2021 2021 Citations: 6
Nitrogenated-carbon nanoelectrocatalyst advertently processed from bio-waste of Allium sativum for oxygen reduction reaction P Kanagavalli, GR Pandey, VS Bhat, M Veerapandian, G Hegde Journal of Nanostructure in Chemistry 11 (3), 343-352 , 2021 2021 Citations: 30
MOST CITED SCHOLAR PUBLICATIONS
Low cost, catalyst free, high performance supercapacitors based on porous nano carbon derived from agriculture waste VS Bhat, P Kanagavalli, G Sriram, NS John, M Veerapandian, M Kurkuri, ... Journal of Energy Storage 32, 101829 , 2020 2020 Citations: 135
Stable and sensitive amperometric determination of endocrine disruptor bisphenol A at residual metal impurities within SWCNT P Kanagavalli, S Senthil Kumar Electroanalysis 30 (3), 445-452 , 2018 2018 Citations: 49
Opto-electrochemical functionality of Ru (II)-reinforced graphene oxide nanosheets for immunosensing of dengue virus non-structural 1 protein P Kanagavalli, M Veerapandian Biosensors and Bioelectronics 150, 111878 , 2020 2020 Citations: 48
In-situ redox-active hybrid graphene platform for label-free electrochemical biosensor: Insights from electrodeposition and electroless deposition P Kanagavalli, C Andrew, M Veerapandian, M Jayakumar TrAC Trends in Analytical Chemistry 143, 116413 , 2021 2021 Citations: 41
Electropolymerized methylene blue on graphene oxide framework for the direct voltammetric detection of gallic acid V Krishnan, E Gunasekaran, C Prabhakaran, P Kanagavalli, V Ananth, ... Materials Chemistry and Physics 295, 127071 , 2023 2023 Citations: 37
Graphene oxide/Cu–MOF-based electrochemical immunosensor for the simultaneous detection of Mycoplasma pneumoniae and Legionella pneumophila antigens in water K Pandiyaraj, RA Elkaffas, MIH Mohideen, S Eissa Scientific Reports 14 (1), 17172 , 2024 2024 Citations: 33
Nitrogenated-carbon nanoelectrocatalyst advertently processed from bio-waste of Allium sativum for oxygen reduction reaction P Kanagavalli, GR Pandey, VS Bhat, M Veerapandian, G Hegde Journal of Nanostructure in Chemistry 11 (3), 343-352 , 2021 2021 Citations: 30
Au nanoparticle-decorated nanoporous PEDOT modified glassy carbon electrode: a new electrochemical sensing platform for the detection of glutathione R Rajaram, P Kanagavalli, S Senthilkumar, J Mathiyarasu Biotechnology and Bioprocess Engineering 25 (5), 715-723 , 2020 2020 Citations: 27
Reduced graphene oxide-based electrochemical aptasensor for the multiplexed detection of imidacloprid, thiamethoxam, and clothianidin in food samples AZ Almenhali, P Kanagavalli, M Abd-Ellah, S Khazaal, N El Darra, S Eissa Scientific Reports 15 (1), 10329 , 2025 2025 Citations: 23
Exploring various carbon nanomaterials-based electrodes modified with polymelamine for the reagentless electrochemical immunosensing of Claudin18. 2 P Kanagavalli, S Eissa Biosensors and Bioelectronics 259, 116388 , 2024 2024 Citations: 23
Electrochemical synthesis of Au-Ni (OH) 2-nanocomposite on glassy carbon electrode as highly active bifunctional electrocatalyst for oxygen evolution and oxygen reduction reactions P Kanagavalli, R Sudha, S Boopathi, SS Kumar Electrochemistry Communications 82, 61-65 , 2017 2017 Citations: 23
Chitosanylated MoO 3 –Ruthenium(II) Nanocomposite as Biocompatible Probe for Bioimaging and Herbaceutical Detection G Pandey, M Marimuthu, P Kanagavalli, V Ravichandiran, ... ACS biomaterials science & engineering 5 (7), 3606-3617 , 2019 2019 Citations: 20
Electropolymerized melamine on electrochemically reduced graphene oxide: growth mechanistics, electrode processing, and amperometric sensing of acyclovir P Kanagavalli, M Natchimuthu Karuppusamy, VS Ganesan, ... Langmuir 39 (9), 3512-3525 , 2023 2023 Citations: 15
Electrochemical properties of Rubpy-reduced graphene oxide synergized by ultrasonication for label-free quercetin sensing SK Arumugasamy, P Kanagavalli, M Veerapandian, M Jayaraman, K Yun Applied Surface Science 537, 147777 , 2021 2021 Citations: 14
Electrochemical tracing of butein using carbon nanoparticles interfaced electrode processed from biowaste P Kanagavalli, S Radhakrishnan, G Pandey, V Ravichandiran, ... Electroanalysis 32 (6), 1220-1225 , 2020 2020 Citations: 13
Electrochemical immunosensor for the predictive cancer biomarker SLFN11 using reduced graphene oxide/MIL-101 (Cr)-NH2 composite P Kanagavalli, RA Elkaffas, MIH Mohideen, S Eissa International Journal of Biological Macromolecules 285, 138174 , 2025 2025 Citations: 12
Redox probe-free electrochemical immunosensor utilizing electropolymerized melamine on reduced graphene oxide for the point-of-care diagnosis of gastric cancer P Kanagavalli, S Eissa Talanta 270, 125549 , 2024 2024 Citations: 12
Molybdenum trioxide hybridized kaempferol: double-powered nanosystem for salvaging oxidative stress and electrochemical immunoprobing of interleukin-6 GR Pandey, P Kanagavalli, K Karnam, KT Arul, P Monisha, CL Dong, ... Materials Today Chemistry 24, 100809 , 2022 2022 Citations: 10
Electrochemical and DFT studies of andrographolide on electrochemically reduced graphene oxide for anti-viral herbaceutical sensor P Kanagavalli, GR Pandey, P Murugan, M Veerapandian Analytica Chimica Acta 1209, 339877 , 2022 2022 Citations: 9
Iron oxide decorated N-doped carbon derived from poly (ferrocene-urethane) interconnects for the oxygen reduction reaction V Premkumar, N Chandrasekaran, K Madasamy, M Kathiresan, ... New Journal of Chemistry 42 (19), 15629-15638 , 2018 2018 Citations: 9
