Dr.Md.Abdul Khaleque
@bsmmu.edu.bd
Consultant, Department of Pediatric Hematology and Oncology.
Bangabandhu Sheikh Mujib Medical University,Dhaka,Bangladesh
Khaleque
Consultant, Department of Pediatric Hematology and Oncology.
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Disciplines
Oncology, Hematology, Pediatrics.
Skills and expertise
Hemoglobinopathies, Congenital Anemia, Diagnosis Treatment Acute Myeloid Leukemia, Chemotherapy, Pediatric Hematology, Cancer Diagnostics, Counseling, Lymphoma, Hodgkin's Lymphoma, Hematologic Diseases, CML, Myelodysplastic Syndromes, Pediatric Oncology, Bone Marrow Diseases, Neuroblastoma, Bone Marrow Examination, Retinoblastoma, disorder.
Contact information
khalequedr@
EDUCATION
MBBS,DCH
RESEARCH, TEACHING, or OTHER INTERESTS
Oncology, Pediatrics, Hematology, Health Professions
Scopus Publications
Scholar Citations
Scholar h-index
Scopus Publications
Sumbleen Ali, Mosammat N. Khatun, Abdul Khaleque, and Ronald P. Rohner
Informa UK Limited
Abstract Prior multicultural meta-analyses have shown that three of the four individual expressions of parental rejection (viz., coldness/lack of affection, hostility/aggression, and indifference/neglect) tend to be significantly associated with all seven of the personality dispositions most central to interpersonal acceptance-rejection theory (IPARTheory). These dispositions include hostility/aggression, dependence, negative self-esteem, negative self-adequacy, emotional instability, emotional unresponsiveness, and negative worldview. However, it was unknown whether the fourth expression of rejection (i.e. undifferentiated rejection) tends to be associated transculturally, as predicted by the theory, with this cluster of dispositions among children. Thus, this meta-analysis investigated 1) the extent to which children’s perceptions of maternal and paternal undifferentiated rejection were related to these personality dispositions, and 2) the extent to which these relations varied by gender of parent. To address these questions, we performed a meta-analysis on 16 studies involving 12,538 children in 14 countries. Results showed significant associations between all seven personality dispositions and both maternal and paternal undifferentiated rejection. The results also showed significantly stronger relations between maternal than paternal undifferentiated rejection on five of the seven indices of children’s personality.
Aura Rahman, Ashley Styczynski, Abdul Khaleque, Sakib Abrar Hossain, Abdus Sadique, Arman Hossain, Mukesh Jain, Syeda Naushin Tabassum, Fahad Khan, Mohammad Sami Salman Bhuiyan,et al.
Springer Science and Business Media LLC
Abstract Background Acinetobacter calcoaceticus-A. baumannii (ACB) complex pathogens are known for their prevalence in nosocomial infections and extensive antimicrobial resistance (AMR) capabilities. While genomic studies worldwide have elucidated the genetic context of antibiotic resistance in major international clones (ICs) of clinical Acinetobacter spp., not much information is available from Bangladesh. In this study, we analysed the AMR profiles of 63 ACB complex strains collected from Dhaka, Bangladesh. Following this, we generated draft genomes of 15 of these strains to understand the prevalence and genomic environments of AMR, virulence and mobilization associated genes in different Acinetobacter clones. Results Around 84% (n = 53) of the strains were extensively drug resistant (XDR) with two showing pan-drug resistance. Draft genomes generated for 15 strains confirmed 14 to be A. baumannii while one was A. nosocomialis. Most A. baumannii genomes fell under three clonal complexes (CCs): the globally dominant CC1 and CC2, and CC10; one strain had a novel sequence type (ST). AMR phenotype-genotype agreement was observed and the genomes contained various beta-lactamase genes including blaOXA-23 (n = 12), blaOXA-66 (n = 6), and blaNDM-1 (n = 3). All genomes displayed roughly similar virulomes, however some virulence genes such as the Acinetobactin bauA and the type IV pilus gene pilA displayed high genetic variability. CC2 strains carried highest levels of plasmidic gene content and possessed conjugative elements carrying AMR genes, virulence factors and insertion sequences. Conclusion This study presents the first comparative genomic analysis of XDR clinical Acinetobacter spp. from Bangladesh. It highlights the prevalence of different classes of beta-lactamases, mobilome-derived heterogeneity in genetic architecture and virulence gene variability in prominent Acinetobacter clonal complexes in the country. The findings of this study would be valuable in understanding the genomic epidemiology of A. baumannii clones and their association with closely related pathogenic species like A. nosocomialis in Bangladesh.
Eshita Reza Khan, Afiqul Islam, Chowdhury Yakub Jamal, Md. Anwarul Karim, ATM Atikur Rahman, Md. Golam Hafiz, and Abdul Khaleque
Informa UK Limited
Abstract Pediatric acute promyelocytic leukemia (APL) is one of the most curable subtypes of acute myeloid leukemia of childhood. But it may have many early complications, especially in developing countries. This study aims to describe the outcome and complications of pediatric APL patients in Bangladesh. This prospective observational study was conducted in the pediatric hematology and oncology department of Bangabandhu Sheikh Mujib Medical University, Dhaka from September 2017 to March 2019. In this study, PML:RAR-α (Promyelocytic leukemia-retinoic acid receptor-α) positive APL cases were included and observed while being treated with risk-directed ATRA (All-trans-retinoic acid) based chemotherapy. Among twenty PML:RAR-α positive APL cases, 13 children were in the high risk group and hemorrhagic manifestations were present in 95% of patients. Post-induction remission was achieved in 85% of the patients. 3-year overall survival was 70% (45-85% with 95% confidence interval). There was no refractory disease or relapses. Neutropenic sepsis was the most common complication and also the most common cause of mortality. In Bangladesh, the 3-year overall survival of pediatric APL is 70% (45-85% with 95% CI). Post-chemotherapy neutropenic sepsis is the most common complication and also the most common cause of mortality in this potentially curable malignancy in Bangladesh.
Matieu Henry, Zaheer Iqbal, Kristofer Johnson, Mariam Akhter, Liam Costello, Charles Scott, Rashed Jalal, Md. Akhter Hossain, Nikhil Chakma, Olaf Kuegler,et al.
Elsevier BV
Abstract Background National forest inventory and forest monitoring systems are more important than ever considering continued global degradation of trees and forests. These systems are especially important in a country like Bangladesh, which is characterised by a large population density, climate change vulnerability and dependence on natural resources. With the aim of supporting the Government’s actions towards sustainable forest management through reliable information, the Bangladesh Forest Inventory (BFI) was designed and implemented through three components: biophysical inventory, socio-economic survey and remote sensing-based land cover mapping. This article documents the approach undertaken by the Forest Department under the Ministry of Environment, Forests and Climate Change to establish the BFI as a multipurpose, efficient, accurate and replicable national forest assessment. The design, operationalization and some key results of the process are presented. Methods The BFI takes advantage of the latest and most well-accepted technological and methodological approaches. Importantly, it was designed through a collaborative process which drew from the experience and knowledge of multiple national and international entities. Overall, 1781 field plots were visited, 6400 households were surveyed, and a national land cover map for the year 2015 was produced. Innovative technological enhancements include a semi-automated segmentation approach for developing the wall-to-wall land cover map, an object-based national land characterisation system, consistent estimates between sample-based and mapped land cover areas, use of mobile apps for tree species identification and data collection, and use of differential global positioning system for referencing plot centres. Results Seven criteria, and multiple associated indicators, were developed for monitoring progress towards sustainable forest management goals, informing management decisions, and national and international reporting needs. A wide range of biophysical and socioeconomic data were collected, and in some cases integrated, for estimating the indicators. Conclusions The BFI is a new information source tool for helping guide Bangladesh towards a sustainable future. Reliable information on the status of tree and forest resources, as well as land use, empowers evidence-based decision making across multiple stakeholders and at different levels for protecting natural resources. The integrated socio-economic data collected provides information about the interactions between people and their tree and forest resources, and the valuation of ecosystem services. The BFI is designed to be a permanent assessment of these resources, and future data collection will enable monitoring of trends against the current baseline. However, additional institutional support as well as continuation of collaboration among national partners is crucial for sustaining the BFI process in future.
Abdul Khaleque, Muhammad Uddin, and Rumana Aktar
Modestum Publishing Ltd
The purpose of this study was to explore the effects of perceived paternal and maternal acceptance on the bicultural orientations and psychological adjustment of ethnic-minority young adults in Bangladesh. The study was based on a sample of 412 young adults (mean age 22 years), consisting of 40% women and 60% men from 18 tribal subgroups in Bangladesh. Measures used were Parental Acceptance–Rejection Questionnaire (PARQ), Bicultural Attitude Scale (BAS) and Personality Assessment Questionnaire (PAQ). Results showed that there are significant positive correlations between perceived parental (paternal and maternal) acceptance, heritage culture, and psychological adjustment of the respondents. Results further showed that perceived paternal acceptance has independent and stronger effect than perceived maternal acceptance on the bicultural orientations and psychological adjustment of the minority young adults in Bangladesh.
Maqsud Hossain, Tahmina Tabassum, Aura Rahman, Arman Hossain, Tamanna Afroze, Abdul Mueed Ibne Momen, Abdus Sadique, Mrinmoy Sarker, Fariza Shams, Ahmed Ishtiaque,et al.
Springer Science and Business Media LLC
AbstractEscherichia coli is a pathogen commonly encountered in clinical laboratories, and is capable of causing a variety of diseases, both within the intestinal tract (intestinal pathogenic strains) and outside (extraintestinal pathogenic E. coli, or ExPEC). It is associated with urinary tract infections (UTIs), one of the most common infectious diseases in the world. This report represents the first comparative analysis of the draft genome sequences of 11 uropathogenic E. coli (UPEC) strains isolated from two tertiary hospitals located in Dhaka and Sylhet, Bangladesh, and is focused on comparing their genomic characteristics to each other and to other available UPEC strains. Multilocus sequence typing (MLST) confirmed the strains belong to ST59, ST131, ST219, ST361, ST410, ST448 and ST4204, with one of the isolates classified as a previously undocumented ST. De novo identification of the antibiotic resistance genes blaNDM-5, blaNDM-7, blaCTX-M-15 and blaOXA-1 was determined, and phenotypic-genotypic analysis of virulence revealed significant heterogeneity within UPEC phylogroups.
Nandita Mitra, Shihab Ahmad Shahriar, Nurunnaher Lovely, Md Shohel Khan, Aweng Eh Rak, S. P. Kar, Md Abdul Khaleque, Mohamad Faiz Mohd Amin, Imrul Kayes, and Mohammed Abdus Salam
MDPI AG
The study represents the estimation of energy-based CO2 emission and the health risks of workers involved in the shipbreaking industries in Sitakunda, Bangladesh. To calculate the carbon emission (CE) from three shipbreaking activities, i.e., metal gas cutting (GC), diesel fuel (FU) and electricity consumption (EC), we used the Intergovernmental Panel on Climate Change (IPCC) guidelines and Environmental Protection Agency (EPA)’s Emission and Generation Resource Integrated Database (eGRID) emission factors. Moreover, the geographic weighted regression (GWR) model was applied to assess the contribution of influencing factors of CE throughout the sampling points. To assess the workers’ health condition and their perceptions on environmental degradation, a semi-structured questionnaire survey among 118 respondents were performed. The results showed that total CO2 emissions from GC were 0.12 megatons (MT), 11.43 MT, and 41.39 MT for daily, monthly, and yearly respectively, and the values were significantly higher than the surrounding control area. Emissions from the FU were estimated as daily: 0.85 MT, monthly: 1.92 MT, and yearly: 17.91 MT, which were significantly higher than EC. The study also revealed that workers were very susceptible to accidental hazards especially death (91%), and pollution (79%). Environmental consequences and health risks of the workers in shipbreaking industry warrant more attention nationally and internationally at the industry-level.
Abdul Khaleque, Muhammad Kamal Uddin, Kazi Nur Hossain, Md. Nur-E-Alam Siddique, and Anjuman Shirin
Springer Science and Business Media LLC
Ronald P. Rohner, Ania Filus, Tatiana Melendez-Rhodes, Behire Kuyumcu, Francisco Machado, Joanna Roszak, Sadiq Hussain, Yun-Joo Chyung, Vincenzo P. Senese, Saeede Daneshmandi,et al.
SAGE Publications
This study assesses interpersonal acceptance-rejection theory’s (IPARTheory’s) prediction that adults’ (both men’s and women’s) remembrances of parental (both maternal and paternal) rejection in childhood are likely to be associated with adults’ fear of intimacy, as mediated by adults’ psychological maladjustment and relationship anxiety. The study also assesses the prediction that these associations will not vary significantly by gender, ethnicity, language, culture, or other such defining conditions. To test these predictions a sample of 3,483 young adults in 13 nations responded to the mother and father versions of the Adult Parental Acceptance-Rejection Questionnaire (short forms), Adult Personality Assessment Questionnaire (short form), the Interpersonal Relationship Anxiety Questionnaire, the Fear of Intimacy Scale, and the Revised Personal Information Form. Results of multigroup analyses showed that adults’ remembrances of both maternal and paternal rejection in childhood independently predicted men’s and women’s fear of intimacy in all 13 countries. However, remembered maternal rejection was a significantly stronger predictor of adults’ fear of intimacy than was remembered paternal rejection. Results also confirmed the prediction in all 13 countries and across both genders that both maternal and paternal rejection independently predicted adults’ psychological maladjustment and relationship anxiety, which in turn predicted fear of intimacy. In addition, psychological maladjustment partially mediated the relation between remembrances of maternal and paternal rejection, and adults’ fear of intimacy in all 13 countries and both genders.
Sumbleen Ali, Nazma Khatun, Abdul Khaleque, and Ronald P. Rohner
SAGE Publications
Extensive cross-cultural evidence supports the conclusion that children and adults everywhere understand themselves to be cared about (accepted) or not cared about (rejected) by the people most important to them (e.g., parents) in four ways. These four ways include the perception of warmth/affection (or coldness/lack of affection), hostility/aggression, indifference/neglect, and undifferentiated rejection. In addition, extensive cross-cultural evidence supports the conclusion that psychological adjustment of children and adults everywhere tends to be affected in the same way when they feel their attachment figures do not care about or love them (i.e., reject them). About 11 prior meta-analyses have documented these conclusions about the relationship between psychological maladjustment and the experiences of parental coldness/lack of affection, hostility/aggression, and indifference/neglect, among offspring. However, the cross-cultural link between psychological maladjustment and undifferentiated rejection has not heretofore been explored via meta-analysis. That is the purpose of this study. It examined relations among children’s current perceptions and adults’ remembrances of parental undifferentiated rejection in childhood, and offspring’s psychological adjustment. The meta-analysis was based on 102 studies (89 published and 13 unpublished) from 17 countries involving 24,003 respondents. Results showed that both maternal and paternal undifferentiated rejection correlated significantly in all countries with overall psychological maladjustment of both children and adults. However, maternal undifferentiated rejection had a significantly stronger relationship with both children’s and adults’ psychological maladjustment than did perceived paternal undifferentiated rejection. Perceived maternal undifferentiated rejection also had a significantly stronger relationship with children’s psychological maladjustment than with adults’ psychological maladjustment.
Mukesh Jain, Sohidul Islam, A. S. M. Zisanur Rahman, Sharmin Akhtar, Kazi Nadim Hasan, Gias Uddin Ahsan, Abdul Khaleque, and Maqsud Hossain
Springer Science and Business Media LLC
Maqsud Hossain, Munirul Alam, Abdul Khaleque, Sohidul Islam, Abdus Sadique, Nayeim Khan, Zahra Halim, Mrinmoy Sarker, Najib M. El-Sayed, Anwar Huq,et al.
American Society for Microbiology
ABSTRACT We report here the first draft genome sequence of the non-O1/non-O139 Vibrio cholerae strain VcN1, isolated from Dhaka, Bangladesh. The data submitted to GenBank for this strain will contribute to advancing our understanding of this environmentally disseminated bacterium, including its virulence and its evolution as an important pathogen.
Abdul Khaleque and Sumbleen Ali
Wiley
Abdul Khaleque
Springer Science and Business Media LLC
Abdul Khaleque
Springer Science and Business Media LLC
Sabina Sultana and Abdul Khaleque
Springer Science and Business Media LLC
Abdul Khaleque, Muhammad Kamal Uddin, Anjuman Shirin, Rumana Aktar, and Samsad Afrin Himi
Springer Science and Business Media LLC
Abdul Khaleque, Farah Malik, and Ronald P. Rohner
Springer Science and Business Media LLC
Sumbleen Ali, Abdul Khaleque, and Ronald P. Rohner
SAGE Publications
This cross-cultural meta-analysis is based on 220 studies involving 33,081 respondents from 23 nations across five continents. The study addressed a major question drawn from the basic postulates of interpersonal acceptance–rejection theory (IPARTheory): Is the psychological adjustment of both males and females universally (i.e., panculturally) associated with children’s and adults’ perceptions of both maternal and paternal acceptance in childhood? To remain true to the major postulates of IPARTheory (formerly known as parental acceptance–rejection theory, PARTheory), all studies included in this meta-analysis used the Parental Acceptance–Rejection Questionnaire for Mothers and Fathers (Child and Adult PARQ: Mother and Father versions), as well as the Personality Assessment Questionnaire (Child and Adult versions). Results showed that both paternal and maternal acceptance correlate significantly with the psychological adjustment of both children and adults across all cultures. The study also showed that there are no gender differences in the relation between children’s perception of parental acceptance and their psychological adjustment. However, remembrances of maternal acceptance in childhood showed significantly stronger relations with adult sons’ current psychological adjustment than that of adult daughters. Moreover, remembrances of paternal acceptance in childhood were found to have significantly stronger relations with adult daughters’ psychological adjustment than did daughters’ remembrances of maternal acceptance.
Abdul Khaleque
Springer Science and Business Media LLC
Sumbleen Ali, Abdul Khaleque, and Ronald P. Rohner
SAGE Publications
This cross-cultural meta-analysis tests the contribution of teachers’ and parents’ acceptance to youth’s psychological adjustment and school conduct. It is based on nine studies involving 2,422 school-going youth in 12 nations. The study addressed two questions drawn from one of the basic postulates of interpersonal acceptance–rejection theory (IPARTheory): (a) To what extent are boys’ and girls’ perceptions of teacher acceptance related internationally to their psychological adjustment and school conduct? (b) To what extent are boys’ and girls’ perceptions of maternal and paternal acceptance related internationally to their psychological adjustment and school conduct? All studies included in this meta-analysis used the child version of the Parental Acceptance–Rejection Questionnaire for Mothers and Fathers (child PARQ: Mother and Father), child version of the Personality Assessment Questionnaire (child PAQ), the Teacher’s Evaluation of Student’s Conduct (TESC), and the Teacher Acceptance–Rejection Questionnaire (TARQ). Results showed that both parental and teacher acceptance correlate significantly in all countries with psychological adjustment and school conduct of children, regardless of gender differences. The study also showed that perceived teacher acceptance has a significantly stronger relation with the school conduct of boys than of girls.
Abdul Khaleque
Palgrave Macmillan