Longxia Xu

RECENT SCHOLAR PUBLICATIONS

Dysregulation of the p300/CBP histone acetyltransferases in human cancer
L Xu, H Xuan, X Shi
Epigenomics, 1-16 , 2025
2025
Citations: 6
A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression
Z Xue, L Qin, H Xuan, K Luo, M Huang, L Xie, Y Su, L Xu, J Harsh, B Dale, ...
Science Advances 10 (35), eado1432 , 2024
2024
Citations: 11
Histone H4K16ac Binding Function of the Triple PHD Finger Cassette of MLL4
VK Sinha, Y Zhang, L Xu, YW Chen, S Picaud, M Zandian, S Biswas, ...
Journal of Molecular Biology 436 (7), 168212 , 2024
2024
Citations: 6
Hotspot Cancer Mutation Impairs KAT8-mediated Nucleosomal Histone Acetylation
H Xuan, L Xu, K Li, F Xuan, T Xu, H Wen, X Shi
Journal of Molecular Biology 436 (7), 168413 , 2024
2024
Citations: 6
Heterobifunctional compounds as degraders of enl
J Jin, HU Kaniskan, QIN Lihuai, H Wen, X Shi, L Xu, Z Xue
US Patent App. 18/032,758 , 2023
2023
Citations: 3
TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition
L Xu, H Xuan, W He, L Zhang, M Huang, K Li, H Wen, H Xu, X Shi
Nature communications 14 (1), 5362 , 2023
2023
Citations: 21
Discovery of selective small-molecule inhibitors for the ENL YEATS domain
XR Ma, L Xu, S Xu, BJ Klein, H Wang, S Das, K Li, KS Yang, S Sohail, ...
Journal of medicinal chemistry 64 (15), 10997-11013 , 2021
2021
Citations: 47
Disruption of Jmjd3/p16 Ink4a Signaling Pathway Causes Bizarre Parosteal Osteochondromatous Proliferation (BPOP)‐like Lesion in Mice
F Zhang, Y Wang, Y Wang, X Wang, D Zhang, X Zhao, R Jiang, Y Gu, ...
Journal of Bone and Mineral Research 36 (10), 1931-1941 , 2020
2020
Citations: 4
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF
Y Zhang, Y Jang, JE Lee, JW Ahn, L Xu, MR Holden, EM Cornett, ...
Nature communications 10 (1), 2314 , 2019
2019
Citations: 55
The histone H3 lysine-27 demethylase Jmjd3 plays a critical role in specific regulation of Th17 cell differentiation
Z Liu, W Cao, L Xu, X Chen, Y Zhan, Q Yang, S Liu, P Chen, Y Jiang, ...
Journal of molecular cell biology 7 (6), 505-516 , 2015
2015
Citations: 128
Histone demethylase JMJD3 is required for osteoblast differentiation in mice
F Zhang, L Xu, L Xu, Q Xu, G Karsenty, CD Chen
Scientific reports 5 (1), 13418 , 2015
2015
Citations: 48
JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice
F Zhang, L Xu, L Xu, Q Xu, D Li, Y Yang, G Karsenty, CD Chen
Journal of molecular cell biology 7 (1), 23-34 , 2015
2015
Citations: 88
In vivo site-specific integration of transgene in silkworm via PhiC31 integrase-mediated cassette exchange
D Long, A Zhao, L Xu, W Lu, Q Guo, Y Zhang, Z Xiang
Insect biochemistry and molecular biology 43 (11), 997-1008 , 2013
2013
Citations: 29
Tet1 is required for Rb phosphorylation during G1/S phase transition
S Huang, Z Zhu, Y Wang, Y Wang, L Xu, X Chen, Q Xu, Q Zhang, X Zhao, ...
Biochemical and biophysical research communications 434 (2), 241-244 , 2013
2013
Citations: 14
Efficient strategies for changing the diapause character of silkworm eggs and for the germline transformation of diapause silkworm strains
AC Zhao, DP Long, SY Ma, LX Xu, MR Zhang, FY Dai, QY Xia, C Lu, ...
Insect science 19 (2), 172-182 , 2012
2012
Citations: 32
Progress in Cre/lox site-specific recombination system in higher eukaryotes
DP Long, B Tan, AC Zhao, LX Xu, ZH Xiang
Yi Chuan= Hereditas 34 (2), 177-189 , 2012
2012
Citations: 10
Progress in research of FLP/ FRT site-specific recombination system in higher eukaryotes.
ZAC Zhao AiChun, LDP Long DingPei, TB Tan Bing, XLX Xu LongXia, ...
2011

MOST CITED SCHOLAR PUBLICATIONS

The histone H3 lysine-27 demethylase Jmjd3 plays a critical role in specific regulation of Th17 cell differentiation
Z Liu, W Cao, L Xu, X Chen, Y Zhan, Q Yang, S Liu, P Chen, Y Jiang, ...
Journal of molecular cell biology 7 (6), 505-516 , 2015
2015
Citations: 128
JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice
F Zhang, L Xu, L Xu, Q Xu, D Li, Y Yang, G Karsenty, CD Chen
Journal of molecular cell biology 7 (1), 23-34 , 2015
2015
Citations: 88
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF
Y Zhang, Y Jang, JE Lee, JW Ahn, L Xu, MR Holden, EM Cornett, ...
Nature communications 10 (1), 2314 , 2019
2019
Citations: 55
Histone demethylase JMJD3 is required for osteoblast differentiation in mice
F Zhang, L Xu, L Xu, Q Xu, G Karsenty, CD Chen
Scientific reports 5 (1), 13418 , 2015
2015
Citations: 48
Discovery of selective small-molecule inhibitors for the ENL YEATS domain
XR Ma, L Xu, S Xu, BJ Klein, H Wang, S Das, K Li, KS Yang, S Sohail, ...
Journal of medicinal chemistry 64 (15), 10997-11013 , 2021
2021
Citations: 47
Efficient strategies for changing the diapause character of silkworm eggs and for the germline transformation of diapause silkworm strains
AC Zhao, DP Long, SY Ma, LX Xu, MR Zhang, FY Dai, QY Xia, C Lu, ...
Insect science 19 (2), 172-182 , 2012
2012
Citations: 32
In vivo site-specific integration of transgene in silkworm via PhiC31 integrase-mediated cassette exchange
D Long, A Zhao, L Xu, W Lu, Q Guo, Y Zhang, Z Xiang
Insect biochemistry and molecular biology 43 (11), 997-1008 , 2013
2013
Citations: 29
TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition
L Xu, H Xuan, W He, L Zhang, M Huang, K Li, H Wen, H Xu, X Shi
Nature communications 14 (1), 5362 , 2023
2023
Citations: 21
Tet1 is required for Rb phosphorylation during G1/S phase transition
S Huang, Z Zhu, Y Wang, Y Wang, L Xu, X Chen, Q Xu, Q Zhang, X Zhao, ...
Biochemical and biophysical research communications 434 (2), 241-244 , 2013
2013
Citations: 14
A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression
Z Xue, L Qin, H Xuan, K Luo, M Huang, L Xie, Y Su, L Xu, J Harsh, B Dale, ...
Science Advances 10 (35), eado1432 , 2024
2024
Citations: 11
Progress in Cre/lox site-specific recombination system in higher eukaryotes
DP Long, B Tan, AC Zhao, LX Xu, ZH Xiang
Yi Chuan= Hereditas 34 (2), 177-189 , 2012
2012
Citations: 10
Dysregulation of the p300/CBP histone acetyltransferases in human cancer
L Xu, H Xuan, X Shi
Epigenomics, 1-16 , 2025
2025
Citations: 6
Histone H4K16ac Binding Function of the Triple PHD Finger Cassette of MLL4
VK Sinha, Y Zhang, L Xu, YW Chen, S Picaud, M Zandian, S Biswas, ...
Journal of Molecular Biology 436 (7), 168212 , 2024
2024
Citations: 6
Hotspot Cancer Mutation Impairs KAT8-mediated Nucleosomal Histone Acetylation
H Xuan, L Xu, K Li, F Xuan, T Xu, H Wen, X Shi
Journal of Molecular Biology 436 (7), 168413 , 2024
2024
Citations: 6
Disruption of Jmjd3/p16 Ink4a Signaling Pathway Causes Bizarre Parosteal Osteochondromatous Proliferation (BPOP)‐like Lesion in Mice
F Zhang, Y Wang, Y Wang, X Wang, D Zhang, X Zhao, R Jiang, Y Gu, ...
Journal of Bone and Mineral Research 36 (10), 1931-1941 , 2020
2020
Citations: 4
Heterobifunctional compounds as degraders of enl
J Jin, HU Kaniskan, QIN Lihuai, H Wen, X Shi, L Xu, Z Xue
US Patent App. 18/032,758 , 2023
2023
Citations: 3
Progress in research of FLP/ FRT site-specific recombination system in higher eukaryotes.
ZAC Zhao AiChun, LDP Long DingPei, TB Tan Bing, XLX Xu LongXia, ...
2011