Louis-Stéphane Le Clercq

Louis S. Le Clercq is a SACNASP registered Molecular Biologist, with a Bachelors of Science (B.Sc.) from the University of Pretoria. Thereafter they completed a B.Sc. Honors as well as a research based Masters of Science (M.Sc) as further post-graduate specialization. This was followed by an internship/stage by the DST-NRF at SANBI. They are currently doing thesis research towards a Ph.D. degree in Genetics at UFS with a focus on molecular clocks and migration, and biological clocks and age.

EDUCATION

PhD (Genetics), 2018 - present, UFS
MSc, 2014, UP
BSc (Hons), 2011, UP
BSc, 2010, UP

RESEARCH, TEACHING, or OTHER INTERESTS

Genetics, Molecular Biology, Animal Science and Zoology, Ecology

RECENT SCHOLAR PUBLICATIONS

Methylation-based markers for the estimation of age in African cheetah, Acinonyx jubatus
LS Le Clercq, A Kotze, JP Grobler, DL Dalton
Molecular Ecology Resources 24 (4) 2024



ABCal: a Python package for author bias computation and scientometric plotting for reviews and meta-analyses
LS Le Clercq
Scientometrics 129, 581–600 2023



ABI Sanger Sequencing of Avian Clock genes to elucidate markers for Migration Phenology
LS Le Clercq, DL Dalton, A Kotz, P Grobler
Protocols.io 2023



PCR Amplification of Clock and Adcyap1 genes with EmeraldAmp GT PCR Master Mix in Avian species for polymorphism elucidation
LS Le Clercq, DL Dalton, A Kotz, P Grobler
Protocols.io 2023



Birds of a feather flock together: a dataset for Clock and Adcyap1 genes from migration genetics studies
LS Le Clercq, G Bazzi, J Ferrer Obiol, JG Cecere, L Gianfranceschi, ...
Scientific Data 10 (1), 787 2023



Designing an EpiTYPER bisulfite sequencing assay for age estimation in Acinonyx jubatus based on human orthologues
LS Le Clercq, DL Dalton, A Kotze, JP Grobler
Protocols.io 2023



DNA extraction protocol for animal blood samples using the EZNA blood mini kit
LS Le Clercq, DL Dalton, A Kotz, JP Grobler
Protocols.io 2023



Dataset generated in a systematic review and meta-analysis of biological clocks as age estimation markers in animal ecology
LS Le Clercq, JP Grobler, A Kotz, DL Dalton
Data in Brief 51, 109615 2023



ABCal: Author Bias Computation and Scientometric Plotting
LS Le Clercq
https://github.com/LSLeClercq/ABCal 2023



AvianClocksData: Dataset of Clock and Adcyap1 alleles for Birds
LS Le Clercq
https://github.com/LSLeClercq/AvianClocksData 2023



Biological clocks as age estimation markers in animals: a systematic review and meta-analysis
LS Le Clercq, A Kotz, JP Grobler, DL Dalton
Biological Reviews 98 (6), 1972-2011 2023



Intra-host quasispecies reconstructions resemble inter-host variability of transmitted chronic hepatitis B virus strains
LS Le Clercq, SM Bowyer, SH Mayaphi
BioRxiv, 1-13 2023



PAReTT: Python Automated Retrieval of TimeTree data
LS Le Clercq
https://github.com/LSLeClercq/PAReTT 2023



Time trees and clock genes: a systematic review and comparative analysis of contemporary avian migration genetics
LS Le Clercq, G Bazzi, JG Cecere, L Gianfranceschi, JP Grobler, A Kotz, ...
Biological Reviews 98 (4), 1051-1080 2023



PAReTT: A Python Package for the Automated Retrieval and Management of Divergence Time Data from the TimeTree Resource for Downstream Analyses
LS Le Clercq, A Kotze, JP Grobler, DL Dalton
Journal of Molecular Evolution 91 (4), 502–513 2023



Biological clock measures: Assessing the association between the circadian and epigenetic clock as predictors of migration phenology and biological aging in wildlife.
LS Le Clercq
University of the Free State 2023



Full genome PCR amplification of all African Hepatitis B Virus genotypes
LS Le Clercq, SM Bowyer, SH Mayaphi
Protocols.io 2021



Molecular age estimation based on promotor CpG methylation using Methylation Sensitive PCR
LS Le Clercq, DL Dalton, A Kotze
9th Annual Research Symposium of the National Zoological Gardens of South Africa 2018



Molecular characterization of full genome hepatitis b virus sequences from an urban hospital cohort in Pretoria, South Africa
LS Le Clercq
University of Pretoria 2014



Full Genome Amplification and Quasispecies Reconstruction of the Hepatitis B Virus from Next Generation Sequencing Data
LS Le Clercq, SM Bowyer, SH Mayaphi
Faculty Day 2014 2014

MOST CITED SCHOLAR PUBLICATIONS

Biological clocks as age estimation markers in animals: a systematic review and meta-analysis
LS Le Clercq, A Kotz, JP Grobler, DL Dalton
Biological Reviews 98 (6), 1972-2011 2023
Citations: 9



Time trees and clock genes: a systematic review and comparative analysis of contemporary avian migration genetics
LS Le Clercq, G Bazzi, JG Cecere, L Gianfranceschi, JP Grobler, A Kotz, ...
Biological Reviews 98 (4), 1051-1080 2023
Citations: 6



Molecular age estimation based on promotor CpG methylation using Methylation Sensitive PCR
LS Le Clercq, DL Dalton, A Kotze
9th Annual Research Symposium of the National Zoological Gardens of South Africa 2018
Citations: 3



Molecular characterization of full genome hepatitis b virus sequences from an urban hospital cohort in Pretoria, South Africa
LS Le Clercq
University of Pretoria 2014
Citations: 2



Birds of a feather flock together: a dataset for Clock and Adcyap1 genes from migration genetics studies
LS Le Clercq, G Bazzi, J Ferrer Obiol, JG Cecere, L Gianfranceschi, ...
Scientific Data 10 (1), 787 2023
Citations: 1



Designing an EpiTYPER bisulfite sequencing assay for age estimation in Acinonyx jubatus based on human orthologues
LS Le Clercq, DL Dalton, A Kotze, JP Grobler
Protocols.io 2023
Citations: 1



DNA extraction protocol for animal blood samples using the EZNA blood mini kit
LS Le Clercq, DL Dalton, A Kotz, JP Grobler
Protocols.io 2023
Citations: 1



Dataset generated in a systematic review and meta-analysis of biological clocks as age estimation markers in animal ecology
LS Le Clercq, JP Grobler, A Kotz, DL Dalton
Data in Brief 51, 109615 2023
Citations: 1