Agricultural and Biological Sciences, Food Science, Organic Chemistry, Analytical Chemistry
23
Scopus Publications
414
Scholar Citations
8
Scholar h-index
6
Scholar i10-index
Scopus Publications
Engineering the interface of cellulose nanocrystals for transient and bioactive iontronics based on protein eutectogels Saul Carrasco-Saavedra, Luis Alfonso Jiménez-Ortega, Robin A. Rojas-Alvarez, Blanca E. Millán-Chiu, Gerardo A. Fonseca-Hernández, et al. Journal of Materials Chemistry C, 2026 Dual physical–chemical modification of cellulose nanocrystals enables high-performance gelatin eutectogels. Dynamic CNC–COOH/TA assemblies impart strain-sensing capability and contact-mediated antibacterial functionality for greener iontronics.
Bioactive Plant Peptides: Physicochemical Features, Structure-Function Insights and Mechanism of Action Sara Avilés-Gaxiola, Israel García-Aguiar, Luis Alfonso Jiménez-Ortega, Erick Paul Gutiérrez-Grijalva, José Basilio Heredia Molecules, 2025 Different cultures worldwide have attributed particular healing abilities to various plants for a long time. After decades of studies, research has demonstrated that their bioactivity is associated mainly with the presence of natural products, including short protein fragments known as peptides. These molecules may occur naturally in plants or be generated from plant protein through enzyme hydrolysis. In recent years, a growing body of evidence has linked plant-derived peptides to diverse biological activities, underscoring the importance of their structural and physicochemical features in determining functionality. Compared with peptides of animal or microbial origin, plant peptides stand out for their high abundance in sustainable sources, low allergenic potential, and distinctive structural traits- such as enrichment in hydrophobic and aromatic residues- that influence their stability, mechanisms of action, and biological functions. This review compiles and analyzes current literature to provide insights into how amino acid composition, secondary structure, net charge, and hydrophobicity influence peptide bioactivity. In addition, the review highlights the mechanisms of action most frequently described for plant peptides. Finally, the article discusses the current landscape and prospects of peptide-based drugs.
Dynamics of the Dissipation of Acetamiprid, Azoxystrobin, and β-Cyfluthrin in Jalapeño Pepper (Capsicum annuum L.) Produced Under Greenhouse and Open-Field Conditions Luis Alfonso Jiménez-Ortega, Jaime Villa-Bojórquez, Pedro de Jesús Bastidas-Bastidas, Rosalba Contreras-Martínez, José Armando Carrillo-Fasio, et al. Foods, 2025 Pepper is one of the most widely consumed foods around the world. China is the leading producer, while Mexico is the primary exporter. To support these roles, the responsible use of agrochemicals is essential. Additionally, investigating the factors influencing pesticide dissipation is critical to ensure that residue levels do not exceed established Maximum Residue Limits (MRLs) and to achieve the required pre-harvest interval (PHI). This is essential to prevent trade-related issues and mitigate potential health risks to consumers. Consequently, this study aims to evaluate the dissipation dynamics of acetamiprid, azoxystrobin, and β-cyfluthrin residues in jalapeño peppers cultivated under both greenhouse and open-field conditions. Three applications of a manufacturer’s suggested dosage were evaluated, with 7-day intervals between each. The residual content was quantified after 1 h and 1, 3, 7, 14, and 21 days following each application. A QuEChERS method utilizing ultra-high-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) and gas chromatography equipped with a micro electron capture detector (GC-µECD) to determine the pesticide residues was optimized and validated, obtaining suitable performance, with satisfactory linearity, detection and quantification limits, recovery rates, and accuracy. The dissipation curves were constructed from the residues and dissipation percentages of the pesticides over time, elucidating the initial residuality, accumulation, half-life, residence time, and total persistence of the active ingredient. In addition, an analysis was carried out, relating climatic conditions to the cumulative dissipation of pesticides. The results show an increase in the initial residues, half-life, and residence time of pesticides in the greenhouse. Otherwise, in the open field, the residues of the pesticides acetamiprid and azoxystrobin increased over the initial applications. Climatic conditions, mainly evapotranspiration during crop growing, involve the dissipation of pesticides in jalapeño pepper. The validation method demonstrated satisfactory parameters, aligning with the guidelines provided by the US EPA and SENASICA. All concentrations quantified in real samples were found to be below the MRLs, ensuring compliance with regulatory standards. Additionally, the dissipation kinetics played a critical role in elucidating key aspects such as residence times, latency periods, and marketing timelines for ensuring food safety. This kinetics provided essential insights into the behavior and persistence of the residues, contributing to a more comprehensive understanding of their dynamics in agricultural and commercial contexts. We believe these findings underscore the reliability and applicability of the method for monitoring pesticide residues in real-world scenarios.
In Silico Tools in the Evaluation of the Anticancer Potential of Phenolic Acids Luis Alfonso Jiménez-Ortega, César Bonifacio Ramírez-López, Beatriz Johanna López-Romero, Katia Lizbeth Alonso-Hurtado, J. Basilio Heredia Molecular Mechanisms of Action of Polyphenols Against Cancer Experimental and in Silico Evaluations, 2025
Role of Major Bioactive Compounds in the Treatment of Anti-aging and Skincare: A Review Gitishree Das, Luis Alfonso Jiménez-Ortega, Sabyasachi Banerjee, Subhasis Banerjee, Sankhadip Bose, et al. Current Pharmaceutical Biotechnology, 2025 Medicinal herbs and herbal formulations have garnered increasing attention in skincare and anti-aging due to their versatility, safety, and potential effectiveness. Korean medicinal herbs and herbal formulations have a rich history in traditional Asian medicine, and they are increasingly gaining recognition as anti-aging and skincare treatments. Korean herbal medicine, known as Hanbang, draws from various natural ingredients, like ginseng, green tea, and licorice, to create herbal formulations passed down for centuries. These formulations are recognized for their potential to promote healthy, youthful skin. Ingredients such as ginseng and green tea possess antioxidant properties that combat free radicals and reduce oxidative stress on the skin, preventing premature aging. Korean skincare treatments often incorporate these herbal formulations, emphasizing natural ingredients and techniques such as herbal masks, teas, and acupuncture to enhance skin vitality and combat aging signs. Understanding the role of major bioactive compounds in Korean herbal medicine is essential for bridging traditional practices with modern dermatological science. Because of the increasing global demand for natural, effective, and safe skincare products, it is increasingly important for natural agents' mechanisms, efficacy, and commercial value to be systematically evaluated and documented. This review aims at fulfilling this knowledge gap as well as providing directions for future research and product development. Considering all the beneficial effects of Korean medicinal herbs, the current review discusses major bioactive compounds present in these herbs and formulations used in anti-aging and skincare treatments, along with their extraction procedure, commercialization, and patents. The review highlights the potential benefits of Korean herbal medicine in promoting youthful, radiant skin through natural and time-honored practices.
Nutraceuticals Enrichment by Genome Editing in Plants Luis Alfonso Jiménez‐Ortega, Jesus Christian Grimaldi‐Olivas, Brandon Estefano Morales‐Merida, J. Basilio Heredia Applications of Genome Engineering in Plants, 2024
Nanoformulations applied to the delivery of alkaloids Laura Aracely Contreras-Angulo, Erick P. Gutiérrez-Grijalva, Luis Angel Cabanillas-Bojórquez, Luis Alfonso Jiménez-Ortega, J. Basilio Heredia Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals, 2022
Functional properties from Jatropha species Recent Studies on Jatropha Research, 2021
Development and validation of a UV–Vis spectrophotometric method for the quantification of affinin in ethanolic extracts of Heliopsis longipes and commercial … CD Martínez-Hernández, C Ibarra-Alvarado, FJ Luna-Vázquez, ... Journal of Food Measurement and Characterization, 1-15 , 2026 2026
Phytochemicals from agricultural and agro-industrial waste: an alternative for the control of phytopathogenic bacteria and fungi. LA Jiménez Ortega, O Valdez Baro, LA Contreras Angulo, ... 2026
Sustainable extraction of phytochemicals from agricultural and food by-products using eutectic solvents and their integration into functional materials LA Jiménez-Ortega, M Marques, MP Quiñonez-Angulo, A Paiva, ... RSC Sustainability 4 (2), 687-719 , 2026 2026 Citations: 1
Engineering the interface of cellulose nanocrystals for transient and bioactive iontronics based on protein eutectogels S Carrasco-Saavedra, LA Jiménez-Ortega, RA Rojas-Alvarez, ... Journal of Materials Chemistry C , 2026 2026
A comprehensive review on the chemical composition and nutraceutical potential of plant-derived sweet compounds, with a highlight on Lippia dulcis Trev. LA Jiménez-Ortega, S Avilés-Gaxiola, O Valdés-Baro, ... Journal of Food Composition and Analysis, 108444 , 2025 2025
Role of Major Bioactive Compounds in the Treatment of Anti-aging and Skincare: A Review. G Das, LA Jiménez-Ortega, S Banerjee, S Bose, G Deswal, AS Grewal, ... Current Pharmaceutical Biotechnology , 2025 2025 Citations: 1
In Silico Tools in the Evaluation of the Anticancer Potential of Phenolic Acids LA Jiménez-Ortega, CB Ramírez-López, BJ López-Romero, ... Molecular Mechanisms of Action of Polyphenols Against Cancer: Experimental … , 2025 2025
Bioactive plant peptides: physicochemical Features, Structure-Function insights and mechanism of action S Avilés-Gaxiola, I García-Aguiar, LA Jiménez-Ortega, ... Molecules 30 (18), 3683 , 2025 2025 Citations: 9
Boosting the Solubility and Bioactivity of Flavonoids in Nontoxic Betaine-Based Natural Eutectic Solvents LA Jiménez-Ortega, K Juarez-Moreno, P Quiñonez-Angulo, J León-Félix, ... ACS Sustainable Chemistry & Engineering 13 (32), 12933-12945 , 2025 2025 Citations: 8
Dynamics of the Dissipation of Acetamiprid, Azoxystrobin, and β-Cyfluthrin in Jalapeño Pepper ( Capsicum annuum L.) Produced Under Greenhouse and Open … LA Jiménez-Ortega, J Villa-Bojórquez, PJ Bastidas-Bastidas, ... Foods 14 (6), 1023 , 2025 2025 Citations: 1
Role of Bioactive Compounds in Plant Disease Management JM Heredia-Bátiz, JP Manjarrez-Quintero, O Valdez-Baro, ... Biotechnological Intervention in Production of Bioactive Compounds … , 2025 2025 Citations: 6
Global Market of Bioactive and Functional Compounds from Marine Resources and Wastes LA Jiménez-Ortega, JP González-Gómez, P Quiñónez-Angulo, ... Bioactive Compounds Extraction from Marine Resources and Wastes, 31-48 , 2025 2025 Citations: 2
Synergistic antioxidant activity in deep eutectic solvents: Extracting and enhancing natural products LA Jiménez-Ortega, J Kumar-Patra, RG Kerry, G Das, JD Mota-Morales, ... ACS Food Science & Technology 4 (12), 2776-2798 , 2024 2024 Citations: 33
Control de fitopatógenos con extractos de biomasa de chile y de maíz LA Jiménez-Ortega, O Valdez-Baro, JM Heredia-Bátiz, RS García-Estrada, ... TIP Revista Especializada en Ciencias Químico-Biológicas 26 (1), 1-11 , 2024 2024 Citations: 2
Anti-obesogenic effects of plant natural products: A focus on Korean traditional foods G Das, LAJ Ortega, S Gonçalves, JB Heredia, MLG Pereira, A Romano, ... Trends in Food Science & Technology 148, 104470 , 2024 2024 Citations: 11
Valorization of agricultural biomass of chili peppers to obtain nutraceuticals LA Jiménez-Ortega, PJ Bastidas-Bastidas, J Basilio Heredia, ... Revista mexicana de ciencias agrícolas 15 (3) , 2024 2024
Valorización de biomasas agrícolas de chiles para la obtención de nutracéuticos LA Jiménez-Ortega, PJ Bastidas-Bastidas, J Basilio Heredia, ... Revista mexicana de ciencias agrícolas 15 (3) , 2024 2024 Citations: 1
Potencial antioxidante y biofuncional de suplementos alimenticios de origen botánico mediante análisis in vitro e in silico: Biofuncionalidad de suplementos alimenticios LA Jiménez-Ortega, BJ López-Romero, JM Heredia-Bátiz, ... Revista Bio Ciencias 11 , 2024 2024
Nutraceuticals enrichment by genome editing in plants LA Jiménez‐Ortega, JC Grimaldi‐Olivas, BE Morales‐Merida, JB Heredia Applications of genome engineering in plants, 282-309 , 2024 2024 Citations: 3
Food byproducts as potential functional ingredients for animal feeding O Valdez-Baro, LA Jiménez-Ortega, LÁ Cabanillas-Bojórquez, ... Food Byproducts Management and Their Utilization, 417-452 , 2024 2024 Citations: 2
MOST CITED SCHOLAR PUBLICATIONS
Wound healing properties of natural products: mechanisms of action MS Criollo-Mendoza, LA Contreras-Angulo, N Leyva-López, ... Molecules 28 (2), 598 , 2023 2023 Citations: 200
Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update G Das, S Gonçalves, JB Heredia, A Romano, LA Jiménez-Ortega, ... Journal of Functional Foods 97, 105045 , 2022 2022 Citations: 58
Synergistic antioxidant activity in deep eutectic solvents: Extracting and enhancing natural products LA Jiménez-Ortega, J Kumar-Patra, RG Kerry, G Das, JD Mota-Morales, ... ACS Food Science & Technology 4 (12), 2776-2798 , 2024 2024 Citations: 33
Deep eutectic solvents can contribute to fight against zero hunger from a sustainable perspective LA Jiménez-Ortega, S Yao, JD Mota-Morales, JB Heredia Journal of Agricultural and Food Chemistry 71 (13), 5027-5029 , 2023 2023 Citations: 18
Optimized Extraction of Glycosylated Flavonoids from Pepper ( Capsicum annuum L.) Agricultural Biomass Residues through Ultrasonic Pulse-Assisted Natural … LA Jiménez-Ortega, PJ Bastidas-Bastidas, MA Angulo-Escalante, ... ACS Sustainable Resource Management 1 (1), 165-177 , 2023 2023 Citations: 16
Anti-obesogenic effects of plant natural products: A focus on Korean traditional foods G Das, LAJ Ortega, S Gonçalves, JB Heredia, MLG Pereira, A Romano, ... Trends in Food Science & Technology 148, 104470 , 2024 2024 Citations: 11
Bioactive plant peptides: physicochemical Features, Structure-Function insights and mechanism of action S Avilés-Gaxiola, I García-Aguiar, LA Jiménez-Ortega, ... Molecules 30 (18), 3683 , 2025 2025 Citations: 9
Boosting the Solubility and Bioactivity of Flavonoids in Nontoxic Betaine-Based Natural Eutectic Solvents LA Jiménez-Ortega, K Juarez-Moreno, P Quiñonez-Angulo, J León-Félix, ... ACS Sustainable Chemistry & Engineering 13 (32), 12933-12945 , 2025 2025 Citations: 8
Desarrollo y evaluación de un yogurt bebible adicionado de extracto liofilizado de Justicia spicigera como colorante natural LAJ Ortega, LB Ramírez, EA Rodríguez e-CUCBA, 25-34 , 2018 2018 Citations: 7
Role of Bioactive Compounds in Plant Disease Management JM Heredia-Bátiz, JP Manjarrez-Quintero, O Valdez-Baro, ... Biotechnological Intervention in Production of Bioactive Compounds … , 2025 2025 Citations: 6
Agave By-Products as Sources of Phytochemicals with Functional Activities and Their Management for Industrial Applications LA Jiménez-Ortega, O Valdez-Baro, M Bernal-Millan, M Rivera-Salas, ... Food Byproducts Management and Their Utilization, 520 , 2023 2023 Citations: 6
Microorganisms as biofactories of powerful agents against plant diseases LA Jiménez-Ortega, AK Orozco-Ochoa, O Valdez-Baro, JB Heredia Entrepreneurship with Microorganisms, 1-15 , 2024 2024 Citations: 5
Chrysobalanus icaco L.: source of phytochemicals with bioactive potential against metabolic syndrome in México LA Jiménez-Ortega, EP Gutiérrez-Grijalva, LA Contreras-Angulo, ... TIP. Revista especializada en ciencias químico-biológicas 24 , 2021 2021 Citations: 5
Assessment of Residuality of Hymexazol in Strawberry ( Fragaria × ananassa ) Crop by a Modified QuEChERS Method and Liquid Chromatography Tandem-Mass … MA Báez-Sañudo, LA Jiménez-Ortega, PJ Bastidas-Bastidas Agronomy 12 (12), 3110 , 2022 2022 Citations: 4
Niveles de fumonisinas en rastrojo de maíz para consumo equino en el estado de Jalisco WP Reyes-Velázquez, CN Anguiano-Sevilla, R Anguiano-Estrella, ... Revista mexicana de ciencias pecuarias 9 (4), 845-854 , 2018 2018 Citations: 4
Nutraceuticals enrichment by genome editing in plants LA Jiménez‐Ortega, JC Grimaldi‐Olivas, BE Morales‐Merida, JB Heredia Applications of genome engineering in plants, 282-309 , 2024 2024 Citations: 3
The Role of Natural Products in the Management of Skin Pigmentary Anomalies LAJ Ortega, MAP Salas, EPG Grijalva, JB Heredia Natural Products for Skin Diseases: A Treasure Trove for Dermatologic … , 2023 2023 Citations: 3
Global Market of Bioactive and Functional Compounds from Marine Resources and Wastes LA Jiménez-Ortega, JP González-Gómez, P Quiñónez-Angulo, ... Bioactive Compounds Extraction from Marine Resources and Wastes, 31-48 , 2025 2025 Citations: 2
Control de fitopatógenos con extractos de biomasa de chile y de maíz LA Jiménez-Ortega, O Valdez-Baro, JM Heredia-Bátiz, RS García-Estrada, ... TIP Revista Especializada en Ciencias Químico-Biológicas 26 (1), 1-11 , 2024 2024 Citations: 2
Food byproducts as potential functional ingredients for animal feeding O Valdez-Baro, LA Jiménez-Ortega, LÁ Cabanillas-Bojórquez, ... Food Byproducts Management and Their Utilization, 417-452 , 2024 2024 Citations: 2