Miklos Gyuranecz

@vmri.hu

Zoonotic Bacteriology and Mycoplasmology
Veterinary Medical Research Institute

Miklos Gyuranecz


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https://researchid.co/m.gyuranecz
I am a DVM, PhD, DSc, habil, Dipl. ECVM, head of a 15-member research group and the vice director of the Veterinary Medical Research Institute, an honorary professor at the University of Veterinary Medicine, Budapest, Hungary and the director of the Mycoplasma diagnostic & biotech company, MolliScience Ltd. I am the author of more than 130 peer-reviewed scientific papers and three book chapters. My laboratory served as an OIE reference laboratory between 2015 and 2018. Currently I am the supervisor of six graduated and three active PhD students.

EDUCATION

2021 De facto Diplomate, European College of Veterinary Microbiology
2021 DSc (Doctor of Science), Hungarian Academy of Sciences, Hungary
2019 Habilitation, University of Veterinary Medicine, Hungary
2011 PhD (Summa cum laude), Faculty of Veterinary Science, Szent István University, Hungary
2007 DVM and BSc in wildlife management, Faculty of Veterinary Science, Szent István University, Hungary

RESEARCH INTERESTS

I am keenly interested in infectious diseases, particularly bacterial pathogens. My current work is primarily on mycoplasmosis but I also work with a variety of other diseases, including tularemia, brucellosis and Q fever.

FUTURE PROJECTS

National Laboratory of Infectious Animal Diseases, Antimicrobial Resistance, Veterinary Public Health and Food Chain Safety

The establishment of the laboratory is of key importance for the national economy, since the rapid recognition of infectious diseases, along with effective prevention and treatment are especially important due to the large number of farm animals in Hungary and the annual increase in revenue they generate. Also playing an important role in the project is the study of the increasingly alarming spread of antimicrobial resistance, especially with regard to the possibility of its transfer from animals to humans. The laboratory's innovative competences and modern infrastructural capacity not only further the nation's human and animal health, they also increase the international competitiveness of domestic livestock breeding.


Applications Invited
PhD students, post-docs

Development of diagnostic and control procedures for infectious diseases of domestic and wild bird species with high economic and public health risk

Most of VMRI's research groups are involved in the research project. The project’s main objectives were generated by the animal health problems caused by viruses, bacteria and parasites that threaten the competitiveness of poultry industry, and that could lead to market improvements for the sector. Research directions have been identified that can effectively help to address the current challenges in poultry nutrition, food chain safety and zoonoses.


Applications Invited
PhD students, post-docs

National Laboratory of Health Safety

The aim of the Health Safety National Laboratory is to create a scientific basis for decision-making in Hungary based on data and analysis in the areas of health care, epidemic prevention and ecological systems. The project encompasses research carried out in the fields of epidemic mathematics, epidemic ecology, invasion biology and data-driven health care, among other topics. The laboratory unites and coordinates the research groups operating in this area in Hungary in an insular fashion along the "One Health" concept, thereby supporting networking and the creation of an effectively collaborative and internationally competitive research community.


Applications Invited
PhD students, post-docs
151

Scopus Publications

4210

Scholar Citations

36

Scholar h-index

97

Scholar i10-index

Scopus Publications

  • Genome-wide association study of Mycoplasma anserisalpingitidis strains for antibiotic susceptibility
    Áron B. Kovács, Enikő Wehmann, Katinka Bekő, Dénes Grózner, Krisztina Bali, et al.
    Scientific Reports, 2026
    Mycoplasma anserisalpingitidis is a facultative pathogenic bacterium affecting waterfowl, predominantly geese and sporadically ducks. Understanding the molecular basis of antimicrobial resistance mechanisms is crucial in the preservation of antibiotic efficiency. This study aimed to elucidate the genetic background of antibiotic susceptibility profiles of 110 M . anserisalpingitidis strains against nine antimicrobial agents. Significant associations between k-mers and five (tylvalosin, tilmicosin, enrofloxacin, lincomycin, spectinomycin) of the nine antimicrobial agents were identified by pyseer. Significant associations were found in multiple coding sequences that encode various members of efflux pumps, epigenetic regulation and topoisomerases among many other groups of functions. Certain k-mers associated with genes found putative prophage-like sequences suggest potential horizontal gene transfer events that could facilitate the acquisition of novel resistance mechanisms. Based on our findings, the genetic background of antimicrobial resistance of M. anserisalpingitidis is composed of multiple factors. Our results not only correlated with the majority of known antibiotic resistance mechanisms (e.g. drug target modification, efflux pumps, methyltransferases) but also showed potentially novel genes that could play a significant role in antimicrobial resistance. The results may serve to expedite the diagnosis of M. anserisalpingitidis antibiotic susceptibility profiles and support the fight against the spreading of resistance.
  • European ring test on the differentiation of wild-type Mycoplasma synoviae and the MS-H vaccine strains in clinical samples
    Cristina Martin Jimenez, Zsuzsa Kreizinger, Miklós Gyuranecz, Peter Cargill
    Poultry Science, 2026
  • Mycoplasma, antibiotics in lay, and antimicrobial resistance (AMR)
    C.J. Morrow, R.A. Achari, M. Charles, G.F. Browning, J.H.P. Ho, et al.
    Poultry Science, 2026
  • Identification and detection of genetic markers associated with antimicrobial susceptibility and evaluation of efflux pump mechanisms in Mycoplasma iowae
    Dominika Buni, Áron Botond Kovács, Enikő Wehmann, Dénes Grózner, Krisztián Bányai, et al.
    Plos One, 2026
    Mycoplasma iowae is an economically significant pathogen that causes reduced hatchability, late embryo mortality and leg deformities, chondrodystrophy and skeletal lesions in poults. While prevention is essential in the control of infection, the appropriate administration of antibiotics may reduce economic losses during outbreaks. As a first step in the exploration of antimicrobial resistance mechanisms in M. iowae , target modification and efflux pump activity were examined in the present study. Point mutations were analyzed in previously described antibiotic binding sites in the whole genome sequences of 99 M. iowae strains. Mismatch amplification mutation assays (MAMAs) were designed and validated for the differentiation of mutations corresponding to elevated minimum inhibitory concentration (MIC) values for fluoroquinolones. Broth microdilution assays were performed to evaluate the effect of efflux pump inhibitors. In the presence of orthovanadate (OV), MIC values were significantly lower than in the absence of OV for spiramycin, tilmicosin, tylosin and oxytetracycline, which may indicate the presence of an active efflux system in M. iowae . Putative promoter regions of efflux-related genes were predicted and characterized. Genetic mutations, previously described in other bacteria, were described to be associated with elevated fluoroquinolone, macrolide and lincomycin MICs in M. iowae , although certain resistant phenotypes remained unexplained, promoting future examinations for deeper insights. The developed MAMAs may support rapid identification of M. iowae strains with elevated MIC values for fluoroquinolones. The better understanding of the efflux pump mechanisms enables the development of alternative methods for the support of therapy against this pathogen.
  • Development and efficacy test of a live, attenuated Mycoplasma hyorhinis vaccine candidate strain
    Eszter Zsófia Nagy, Levente Szeredi, Dorottya Földi, Nikolett Belecz, Áron Botond Kovács, et al.
    Vaccine, 2026
  • Development of Nanopore amplicon sequencing method for culture-free genotyping of Bacillus anthracis strains directly from environmental samples
    Ágnes Nagy, Gábor Endre Tóth, Péter Sály, Csaba István Pereszlényi, Gergely Csaba Babinszky, et al.
    Frontiers in Microbiology, 2026
    Fast and accurate genetic subtyping of pathogens is required to respond appropriately to biological events caused by natural outbreaks or bioattacks involving anthrax. In this study, we developed and validated a culture-free genotyping method that combines a multiplex PCR-based amplicon sequencing method on the Nanopore platform with in silico multiple-locus variable-number tandem repeat analysis (MLVA) of 31 loci to identify an unknown Bacillus anthracis strain directly from environmental samples. The novel method accurately identified repeat numbers for all loci in 12 different MLVA genotype Bacillus anthracis strains analyzed in the study, matching 100% with the reference capillary electrophoresis and Sanger sequencing results. The detection limit of the method, at which all 31 variable-number tandem repeat loci were successfully identified, was found to be 10 4 CFU spores/sample for pure spore samples and at 10 6 CFU spores/sample for spiked environmental samples from three matrices (soil, swab, and muddy water). Specificity tests yielded negative results for samples containing only non- Bacillus anthracis members of the Bacillus cereus group, which produced sequencing reads for 15 loci but were non-specific to Bacillus anthracis. To validate the method, we genotyped 11 Bacillus anthracis strains originating from a historical collection of Hungarian isolates. The MLVA31 typing scheme classified the strains into five groups, four of which fell into the A.Br.008/009 Trans-Eurasian (TEA) group within the clade A, and one into the B.Br.CNEVA group within the clade B. The largest group within clade A comprises six strains that are assumed to be members of the dominant Bacillus anthracis population in Hungary. Our results demonstrate that PCR-based amplicon sequencing using the portable MinION device is highly effective for on-site genotyping of pathogens directly from environmental samples. This establishes the NGS-based MLVA genotyping as a valuable tool for biodefense laboratories in preliminary forensic investigations of bioterrorism-related anthrax outbreaks. Furthermore, our results provide new insights into the genetic diversity of Bacillus anthracis in a region (Hungary, Central Europe) that is underrepresented in research and has limited scientific data.
  • Temperature-dependent survival of Mycoplasma anserisalpingitidis in water: implications for biosecurity and transmission in waterfowl farming
    Anna Sawicka-Durkalec, Zsuzsa Kreizinger, Dénes Grózner, Olimpia Kursa, Grzegorz Tomczyk, et al.
    BMC Veterinary Research, 2025
    Background Mycoplasma anserisalpingitidis is an emerging waterfowl pathogen associated with reproductive tract infections, embryo mortality, and reduced egg production. While direct and vertical transmission routes have been described, its environmental persistence remains poorly understood. In waterfowl production systems, open water sources can be used for drinking and bathing, potentially facilitating indirect transmission. Prolonged survival in such environments may extend the period during which birds are exposed to the pathogen. Understanding the ability of M. anserisalpingitidis to survive outside the host, particularly under environmental stress, is essential for assessing transmission risks. Results This study evaluated the survival of two M. anserisalpingitidis strains in water at environmental temperatures of 0 °C, 4 °C, and 22 °C. To our knowledge, this is the first study to compare environmental survival between two strains of an avian mycoplasma species. Survival was found to be both temperature-dependent and strain-specific. Strain A remained viable for up to 12 days at 0 °C and 8 days at 4 °C, while strain B survived for the entire 28-day experiment at both temperatures. At 22 °C, strain A lost viability within 24 h, while strain B persisted for 3 days. qPCR analysis of DNA concentrations confirmed these survival patterns, indicating better recovery of strain B under low-temperature conditions. Conclusions These findings demonstrate the capacity of M. anserisalpingitidis to persist in cold water and highlight the potential role of water sources as environmental reservoirs contributing to indirect transmission in waterfowl farming. The results emphasize the importance of considering water systems as potential environmental reservoirs when designing biosecurity and disease control strategies.
  • Cross-sectional study of Mycoplasma hyopharyngis, Mycoplasma hyopneumoniae, Mycoplasma hyorhinis and Mycoplasma hyosynoviae in the tonsils of fattening pigs from Central-Eastern Europe
    Eszter Zsófia Nagy, Dorottya Földi, Fruzsina Madzig, Enikő Wehmann, Adél Orosz, et al.
    Porcine Health Management, 2025
    Background Mycoplasma (M.) hyopharyngis, M. hyopneumoniae, M. hyorhinis, and M. hyosynoviae can all be transiently present in the swine tonsils without causing any clinical signs or lesions. M. hyopharyngis is considered a commensal bacterium, however, our knowledge about its prevalence and pathogenic capabilities is lacking. M. hyopneumoniae, M. hyorhinis and M. hyosynoviae are widespread pathogens, responsible for significant economic losses. M. hyopneumoniae is known as the causative agent of porcine enzootic pneumonia, while M. hyorhinis and M. hyosynoviae are associated with arthritis and polyserositis. The objective of this study was to evaluate the detection rates of these mycoplasmas in Central-Eastern Europe (Croatia, the Czech Republic, Hungary, and Slovakia) through a cross-sectional investigation. In parallel, a novel quantitative polymerase chain reaction (qPCR) assay was designed targeting M. hyopharyngis to facilitate the identification of this bacterium. Results Tonsils of 15 animals per herd were sampled from six-month-old fattening pigs, and a total of 150 herds were examined. Tonsils form each herd were divided into three pools, each comprising five tonsils. The samples were submitted for species-specific TaqMan assay and isolation. M. hyopharyngis was identified in 92.67% (139/150, 95% confidence interval: 87.35–95.86%) of the stocks, with successful isolation from 20 herds. Besides, M. hyopneumoniae was detected in 51.33% (77/150, 95% confidence interval: 43.40-59.19%) of the stocks. Additionally, M. hyorhinis was identified in all herds (100.00%; 150/150, 95% confidence interval: 97.50–100.00%) by qPCR examination and was successfully isolated from 107 stocks. Regarding the occurrence of M. hyosynoviae, 88.00% (132/150, 95% confidence interval: 81.83–92.27) of the herds showed positive PCR results, and the pathogen was successfully isolated in 122 cases. Moreover, the newly developed M. hyopharyngis qPCR assay proved to be a reliable and sensitive method. Conclusions This study determined the detection rates of several porcine mycoplasmas (M. hyopharyngis, M. hyopneumoniae, M. hyorhinis, and M. hyosynoviae) in fattening pigs in Central-Eastern Europe. Additionally, the developed M. hyopharyngis qPCR assay may facilitate future prevalence studies and diagnostic procedures concerning this neglected bacterium.
  • Antimicrobial susceptibility profiles of Mycoplasma hyosynoviae strains isolated from five European countries between 2018 and 2023
    Ulrich Klein, Dorottya Földi, Eszter Zsófia Nagy, Lilla Tóth, Nikolett Belecz, et al.
    Scientific Reports, 2025
  • Advancing standardization of diagnostics and antimicrobial susceptibility testing for pathogenic mycoplasmas of livestock origin: insights from the MyMIC network
    Maryne Jaÿ, Sara M. Klose, Marco Bottinelli, Tiina Autio, Claire A.M. Becker, et al.
    BMC Veterinary Research, 2025
    Background Mycoplasma infections pose a significant economic burden and represent a serious health and welfare concern for the livestock sector. Their control often requires repeated antimicrobial treatments. Antimicrobial susceptibility testing (AST) procedures for veterinary mycoplasmas lack standardization. Furthermore, clinical breakpoints (CBPs) are not available to interpret AST data (i.e., Minimum Inhibitory Concentration, MIC values) and categorize isolates as susceptible, resistant, or intermediate to the different antimicrobials used in livestock, nor epidemiological cut-offs (ECOFFs), which are a prerequisite to define CBPs. In 2023, the MyMIC network - a consortium of 22 laboratories specializing in veterinary mycoplasmas- was established to support efforts in standardizing diagnostics and AST, including clinical interpretation. Its initial goals were to (i) review routine diagnostic practices in frontline laboratories and examine veterinarians’ prescribing habits and (ii) assess practices for culture, identification and AST used in expert laboratories and how these practices may affect MIC results as collected for five major livestock pathogens (M. bovis , M. gallisepticum , M. synoviae , M. hyopneumoniae and M. hyorhinis ). Results A first survey targeting veterinarians from the avian, porcine, and ruminant livestock sectors provided 468 complete responses from 39 countries worldwide, giving an account of current trends in the treatment and first-line diagnosis of veterinary mycoplasmoses. Macrolides, tetracyclines, pleuromutilins, florfenicol and fluoroquinolones were the most frequently administered antimicrobials, with usage varying by livestock sector. Veterinarians reported requesting diagnostic in 40–75% of clinical cases, but only one-third requested AST regularly. A separate survey within the consortium highlighted significant variability in the media and methods used by specialized laboratories, particularly for MIC determination, which relied mostly on in-house broth dilution techniques. This methodological diversity limited our ability to aggregate collected MIC data for establishing ECOFFs. Conclusions Several concerns regarding best practices for antimicrobial treatments of mycoplasma infections may be linked to the lack of AST in frontline laboratories. Based on information collected in expert laboratories, we identified multiple sources contributing to inconsistent MIC results. The next step will be to establish consensus gold-standard AST methods tailored to specific mycoplasma-antimicrobial combinations to generate reliable MIC data for defining ECOFFs. Subsequently, the development of ready-to-use commercial MIC plates for use in frontline laboratory will support veterinarians in selecting appropriate treatments.
  • Cross-sectional study of Mycoplasma (M.) hyopharyngis, M. hyopneumoniae, M. hyorhinis and Mycoplasma hyosynoviae in fattening pigs (secondary publication)
    Eszter Zsófia Nagy, Dorottya Földi, Fruzsina Madzig, Enikő Wehmann, Adél Orosz, et al.
    Magyar Allatorvosok Lapja, 2025
  • Efficacy test of a Mycoplasma hyorhinis mRNA-LNP vaccine candidate
    Eszter Zsófia Nagy, Levente Szeredi, Hiromi Muramatsu, Noémi Nagy, Dénes Grózner, et al.
    Vaccine X, 2025
  • Mycoplasma gallisepticum and Mycoplasma synoviae in commercial poultry: current control strategies and future challenges
    Anneke Feberwee, Naola Ferguson-Noel, Salvatore Catania, Marco Bottinelli, Nadeeka Wawagema, et al.
    Avian Pathology, 2025
  • Molecular detection of antimicrobial resistance in livestock mycoplasmas: current status and future prospects
    Kinga M. Sulyok, Zsuzsa Kreizinger, Dorottya Földi, Áron Botond Kovács, Dénes Grózner, et al.
    Frontiers in Veterinary Science, 2025
  • Genomic analysis of the 2017 Aotearoa New Zealand outbreak of Mycoplasma bovis and its position within the global population structure
    Barbara M. Binney, Edna Gias, Jonathan Foxwell, Alvey Little, Patrick J. Biggs, et al.
    Frontiers in Microbiology, 2025
  • Mycoplasma hyopharyngis isolated from the joint of a weaner: A case report
    Dorottya Földi, Eszter Zsófia Nagy, Gergely Tóth, László Makrai, László Gombos, et al.
    Acta Veterinaria Hungarica, 2024
  • First detection of mycoplasmosis in a bearded dragon (Pogona vitticeps) in Hungary
    Árisz Ziszisz, Márton Hoitsy, Viktória Sós-Koroknai, Endre Sós, Anna Linda Nógrádi, et al.
    Magyar Allatorvosok Lapja, 2024
  • Evaluating the dynamics and efficacy of a live, attenuated Mycoplasma anserisalpingitidis vaccine candidate under farm conditions
    Dénes Grózner, Zsuzsa Kreizinger, Alexa Mitter, Katinka Bekő, Dominika Buni, et al.
    Avian Pathology, 2024
  • Evaluation of a Method for Standardized Antimicrobial Susceptibility Testing with Mycoplasma hyorhinis Field Isolates
    Lisa Käbisch, Anne-Kathrin Schink, Doris Hoeltig, Jutta Verspohl, Miklós Gyuranecz, et al.
    Microorganisms, 2023
  • Molecular-phylogenetic analyses of Ixodes species from South Africa suggest an African origin of bird-associated exophilic ticks (subgenus Trichotoixodes)
    Sándor Hornok, Jenő Kontschán, Nóra Takács, Heloise Heyne, Áron Botond Kovács, et al.
    Parasites and Vectors, 2023
  • Development of molecular assays for the analysis of genetic relationships of Mycoplasma iowae
    Dominika Buni, Áron Botond Kovács, Dorottya Földi, Krisztián Bányai, Krisztina Bali, et al.
    Veterinary Microbiology, 2023
  • The core genome multi-locus sequence typing of Mycoplasma anserisalpingitidis
    Áron Botond Kovács, Zsuzsa Kreizinger, Barbara Forró, Dénes Grózner, Alexa Mitter, et al.
    Magyar Allatorvosok Lapja, 2023
  • Rapid and sensitive detection of waterfowl mycoplasmas using TaqMan assays
    Edina Nemesházi, Enikő Wehmann, Dénes Grózner, Dorottya Sára Nagy, Áron Botond Kovács, et al.
    Plos One, 2023
  • Characterization of atypical Mycoplasma anserisalpingitidis strains
    Áron B. Kovács, Enikő Wehmann, Dénes Grózner, Krisztina Bali, Edina Nemesházi, et al.
    Veterinary Microbiology, 2023
  • A field study to assess the effectiveness of tylvalosin in drinking water for the treatment of respiratory disease associated with Mycoplasma hyopneumoniae in fattening pigs
    István Filipsz, Ervin Albert, Imre Biksi, Dorottya Földi, Miklós Gyuranecz, et al.
    Magyar Allatorvosok Lapja, 2023

RECENT SCHOLAR PUBLICATIONS

  • European Ring Test on the Differentiation of Wild-Type Mycoplasma synoviae and the MS-H Vaccine Strains in Clinical Samples
    CM Jimenez, Z Kreizinger, M Gyuranecz, P Cargill
    Poultry Science, 107166 , 2026
    2026
  • Real-time monitoring of metabolic plasticity in Mycoplasma gallisepticum under varying nutrient conditions via DART-HRMS
    M Bottinelli, C Zacometti, A Massaro, A Tondo, D Prataviera, B Colò, ...
    Scientific Reports , 2026
    2026
  • Mycoplasma, antibiotics in lay, and Antimicrobial resistance (AMR)
    CJ Morrow, RA Achari, M Charles, GF Browning, JHP Ho, M Cai, ...
    Poultry Science, 107095 , 2026
    2026
  • Identification and detection of genetic markers associated with antimicrobial susceptibility and evaluation of efflux pump mechanisms in Mycoplasma iowae
    D Buni, ÁB Kovács, E Wehmann, D Grózner, K Bányai, EZ Nagy, ...
    PloS one 21 (4), e0347345 , 2026
    2026
  • Supplementary data–Mycoplasma hyorhinis vaccine strain–Nagy, 2026
    EZ Nagy, L Szeredi, D Földi, N Belecz, ÁB Kovács, KM Sulyok, D Grózner, ...
    ARP , 2026
    2026
  • Development of Nanopore amplicon sequencing method for culture-free genotyping of Bacillus anthracis strains directly from environmental samples
    Á Nagy, GE Tóth, P Sály, CI Pereszlényi, GC Babinszky, L Makrai, ...
    Frontiers in Microbiology 17, 1771578 , 2026
    2026
  • Development and efficacy test of a live, attenuated Mycoplasma hyorhinis vaccine candidate strain
    EZ Nagy, L Szeredi, D Földi, N Belecz, ÁB Kovács, KM Sulyok, D Grózner, ...
    Vaccine 75, 128278 , 2026
    2026
  • Genome-wide association study of Mycoplasma anserisalpingitidis strains for antibiotic susceptibility
    ÁB Kovács, E Wehmann, K Bekő, D Grózner, K Bali, Z Kreizinger, ...
    Scientific Reports , 2026
    2026
  • Advancing standardization of diagnostics and antimicrobial susceptibility testing for pathogenic mycoplasmas of livestock origin: insights from the MyMIC network
    M Jaÿ, SM Klose, M Bottinelli, T Autio, CAM Becker, J Bokma, C Boland, ...
    BMC Veterinary Research 21 (1), 712 , 2025
    2025
  • Molecular detection of antimicrobial resistance in livestock mycoplasmas: current status and future prospects
    KM Sulyok, Z Kreizinger, D Földi, ÁB Kovács, D Grózner, L Manso-Silván, ...
    Frontiers in Veterinary Science 12, 1699077 , 2025
    2025
    Citations: 1
  • Temperature-dependent survival of Mycoplasma anserisalpingitidis in water: implications for biosecurity and transmission in waterfowl farming
    A Sawicka-Durkalec, Z Kreizinger, D Grózner, O Kursa, G Tomczyk, ...
    BMC Veterinary Research 21 (1), 603 , 2025
    2025
  • Cross-sectional study of Mycoplasma (M.) hyopharyngis, M. hyopneumoniae, M. hyorhinis and Mycoplasma hyosynoviae in fattening pigs (secondary publication)
    NE Zsofia, F Dorottya, M Fruzsina, W Eniko, O Adel, K Andras, B Laszlo, ...
    MAGYAR ALLATORVOSOK LAPJA 147 (10), 597-608 , 2025
    2025
  • Mycoplasma (M.) hyopharyngis, M. hyopneumoniae, M. hyorhinis és M. hyosynoviae előfordulási gyakoriságának felmérése hízósertésekben (Rövidített másodközlés).
    NE Zsófia, F Dorottya, M Fruzsina, W Enikő, O Adél, K András, B László, ...
    Magyar Állatorvosok Lapja 147 (10) , 2025
    2025
  • Monitoring how the metabolic behavior of mycoplasmas is affected by the nutrients: a proof-of-concept demonstration on Mycoplasma gallisepticum by DART-HRMS
    M Bottinelli, C Zacometti, A Massaro, A Tondo, D Prataviera, B Colò, ...
    2025
  • Efficacy test of a Mycoplasma hyorhinis mRNA-LNP vaccine candidate
    EZ Nagy, L Szeredi, H Muramatsu, N Nagy, D Grózner, Z Kreizinger, ...
    Vaccine: X 25, 100684 , 2025
    2025
  • Genomic analysis of the 2017 Aotearoa New Zealand outbreak of Mycoplasma bovis and its position within the global population structure
    BM Binney, E Gias, J Foxwell, A Little, PJ Biggs, N French, C Lambert, ...
    Frontiers in Microbiology 16, 1600146 , 2025
    2025
    Citations: 4
  • Cross-sectional study of Mycoplasma hyopharyngis , Mycoplasma hyopneumoniae , Mycoplasma hyorhinis and Mycoplasma hyosynoviae in the tonsils of …
    EZ Nagy, D Földi, F Madzig, E Wehmann, A Orosz, A Kempf, L Buza, ...
    Porcine Health Management 11 (1), 11 , 2025
    2025
    Citations: 1
  • Mycoplasma gallisepticum and Mycoplasma synoviae in commercial poultry: current control strategies and future challenges
    A Feberwee, N Ferguson-Noel, S Catania, M Bottinelli, N Wawagema, ...
    Avian Pathology 54 (2), 168-174 , 2025
    2025
    Citations: 12
  • Antimicrobial susceptibility profiles of Mycoplasma hyosynoviae strains isolated from five European countries between 2018 and 2023
    U Klein, D Földi, EZ Nagy, L Tóth, N Belecz, K Költő, E Wehmann, ...
    Scientific Reports 15 (1), 1243 , 2025
    2025
    Citations: 2
  • Development and evaluation of a harmonized antimicrobial susceptibility testing method for porcine Mycoplasma hyorhinis
    L Käbisch, AK Schink, D Höltig, J Verspohl, M Gyuranecz, J Spergser, ...
    Abstract booklet: 10th Symposium on Antimicrobial Resistance in Animals and … , 2025
    2025

MOST CITED SCHOLAR PUBLICATIONS

  • Tularaemia: clinical aspects in Europe
    M Maurin, M Gyuranecz
    The Lancet Infectious Diseases 16 (1), 113-124 , 2016
    2016
    Citations: 347
  • Worldwide phylogenetic relationship of avian poxviruses
    M Gyuranecz, JT Foster, Á Dán, HS Ip, KF Egstad, PG Parker, ...
    Journal of virology 87 (9), 4938-4951 , 2013
    2013
    Citations: 191
  • Melt analysis of mismatch amplification mutation assays (Melt-MAMA): a functional study of a cost-effective SNP genotyping assay in bacterial models
    DN Birdsell, T Pearson, EP Price, HM Hornstra, RD Nera, N Stone, ...
    PLoS One 7 (3), e32866 , 2012
    2012
    Citations: 128
  • Investigation of the Ecology of Francisella tularensis During an Inter-Epizootic Period
    M Gyuranecz, K Rigó, Á Dán, G Földvári, L Makrai, B Dénes, L Fodor, ...
    Vector-Borne and Zoonotic Diseases 11 (8), 1031-1035 , 2011
    2011
    Citations: 114
  • Detection of Brucella Canis –Induced Reproductive Diseases in a Kennel
    M Gyuranecz, L Szeredi, Z Rónai, B Dénes, L Dencso, Á Dán, N Pálmai, ...
    Journal of veterinary diagnostic investigation 23 (1), 143-147 , 2011
    2011
    Citations: 112
  • Molecular detection of vector-borne bacteria in bat ticks (Acari: Ixodidae, Argasidae) from eight countries of the Old and New Worlds
    S Hornok, K Szőke, ML Meli, AD Sándor, T Görföl, P Estók, Y Wang, VT Tu, ...
    Parasites & vectors 12 (1), 50 , 2019
    2019
    Citations: 104
  • Phylogeography of Francisella tularensis subsp. holarctica, Europe
    M Gyuranecz, DN Birdsell, W Splettstoesser, E Seibold, ...
    Emerging infectious diseases 18 (2), 290 , 2012
    2012
    Citations: 98
  • Prevalence of Coxiella burnetii in Hungary: Screening of Dairy Cows, Sheep, Commercial Milk Samples, and Ticks
    M Gyuranecz, B Dénes, S Hornok, P Kovács, G Horváth, V Jurkovich, ...
    Vector-Borne and Zoonotic Diseases 12 (8), 650-653 , 2012
    2012
    Citations: 91
  • Mutations associated with decreased susceptibility to seven antimicrobial families in field and laboratory-derived Mycoplasma bovis strains
    KM Sulyok, Z Kreizinger, E Wehmann, I Lysnyansky, K Bányai, S Marton, ...
    Antimicrobial agents and chemotherapy 61 (2), 10.1128/aac. 01983-16 , 2017
    2017
    Citations: 89
  • Synanthropic Birds Associated with High Prevalence of Tick-Borne Rickettsiae and with the First Detection of Rickettsia aeschlimannii in Hungary
    S Hornok, T Csörgő, J de la Fuente, M Gyuranecz, C Privigyei, ML Meli, ...
    Vector-Borne and Zoonotic Diseases 13 (2), 77-83 , 2013
    2013
    Citations: 88
  • First detection of bartonellae in a broad range of bat ectoparasites.
    S Hornok, R Kovács, ML Meli, E Gönczi, R Hofmann-Lehmann, ...
    Veterinary Microbiology 159 (3-4), 541-543 , 2012
    2012
    Citations: 83
  • Tularemia of European Brown Hare ( Lepus europaeus ) A Pathological, Histopathological, and Immunohistochemical Study
    M Gyuranecz, L Szeredi, L Makrai, L Fodor, ÁR Mészáros, B Szépe, ...
    Veterinary Pathology 47 (5), 958-963 , 2010
    2010
    Citations: 79
  • Unique genomic organization of a novel Avipoxvirus detected in turkey (Meleagris gallopavo)
    K Bányai, V Palya, B Dénes, R Glávits, É Ivanics, B Horváth, SL Farkas, ...
    Infection, Genetics and Evolution 35, 221-229 , 2015
    2015
    Citations: 67
  • First isolation and characterization of Brucella microti from wild boar
    Z Rónai, Z Kreizinger, Á Dán, K Drees, JT Foster, K Bányai, S Marton, ...
    BMC veterinary research 11 (1), 147 , 2015
    2015
    Citations: 67
  • Antibiotic susceptibility profiles of Mycoplasma bovis strains isolated from cattle in Hungary, Central Europe
    KM Sulyok, Z Kreizinger, L Fekete, V Hrivnák, T Magyar, S Jánosi, ...
    BMC veterinary research 10 (1), 256 , 2014
    2014
    Citations: 67
  • New antimicrobial susceptibility data from monitoring of Mycoplasma bovis isolated in Europe
    U Klein, A de Jong, M Youala, F El Garch, C Stevenin, H Moyaert, M Rose, ...
    Veterinary microbiology 238, 108432 , 2019
    2019
    Citations: 63
  • Screening of bat faeces for arthropod-borne apicomplexan protozoa: Babesia canis and Besnoitia besnoiti -like sequences from Chiroptera
    S Hornok, P Estók, D Kováts, B Flaisz, N Takács, K Szőke, A Krawczyk, ...
    Parasites & Vectors 8 (1), 441 , 2015
    2015
    Citations: 63
  • Antibiotic susceptibility profiles of Mycoplasma synoviae strains originating from Central and Eastern Europe
    Z Kreizinger, D Grózner, KM Sulyok, K Nilsson, V Hrivnák, D Benčina, ...
    BMC veterinary research 13 (1), 342 , 2017
    2017
    Citations: 60
  • A serosurvey of flavivirus infection in horses and birds in Slovakia
    T Csank, P Drzewnioková, Ľ Korytár, P Major, M Gyuranecz, J Pistl, ...
    Vector-Borne and Zoonotic Diseases 18 (4), 206-213 , 2018
    2018
    Citations: 57
  • Q fever epidemic in Hungary, April to July 2013
    M Gyuranecz, KM Sulyok, E Balla, T Mag, A Balazs, Z Simor, B Dénes, ...
    Eurosurveillance 19 (30), 20863 , 2014
    2014
    Citations: 51

GRANT DETAILS

2022-2027 Lendület II (Momentum) program
2022-2026 National Laboratory of Infectious Animal Diseases, Antimicrobial Resistance, Veterinary Public Health and Food Chain Safety
2022-2026 National Laboratory of Health Safety
2022-2025 Improving the diagnostics and control of production and zoonotic diseases of poultry and wild birds
2021-2023 Antimicrobial resistance in animal production
2021-2025 Characterization of Mycoplasma iowae strains and improving the therapy of infection
2019-2023 Novel strategies in Mycoplasma control
2019-2021 Pan-European resistance monitoring program of M. hyorhinis
2018-2020 Mycopath III: Pan-European resistance monitoring program of M. bovis, M. hypneumoniae, M. gallisepticum and M. synoviae
2017-2021 Studying the virulence mechanisms of Mycoplasma gallisepticum and M. synoviae
2016-2020 Improving the control of Mycoplasma synoviae infection
2015-2016 Mycopath II: Pan-European resistance monitoring program of M. bovis, M. hypneumoniae, M. gallisepticum and M. synoviae
2013-2016 EU FP7-HEALTH-2013-INNOVATION-1:
2012-2017 Lendület I (Momentum) program
2012 National Institute of Health – USA (NIH) travel grant
2012 Hungarian Academy of Sciences Junior Travel Award
2010-2012 Mycopath I: Pan-European resistance monitoring program of M. bovis, M. hypneumoniae, M. gallisepticum and M. synoviae
2009-2012 Comparative characterization of Francisella tularensis strains

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

- P 21 00357: Live, attenuated Mycoplasma anserisalpingitidis vaccine candidate
- Beside fundamental research we provide diagnostic, contract and training services globally.
- We produce In Vitro Diagnostics (IVD) under our own brand and sell know-how under royalty agreement to different producers.
- We are proud that BioChek B.V. (The Netherlands), the global market leader company in the field of poultry diagnostics, has bought under a royalty agreement our DIVA tests which differentiate Mycoplasma gallisepticum and M. synoviae wild-type and vaccine strains.

CONSULTANCY

My team collaborate with farmers, veterinarians, contract sponsors and academic institutions. Our multidisciplinary team is qualified and experienced in conducting a wide range of studies from laboratory related research and development projects, via animal facility based experiments to field studies.

We also provide diagnostic services globally. During our servicies we help to design the sampling to be the most appropriate and cost-effective for each special case. We help to interpret the results and give personal advice, such as what additional diagnostic tests can be performed. We are also able to suggest treatment options as well as eradication and control measures such as vaccination or monitoring plan.

Industry, Institute, or Organisation Collaboration

We collaborate with several research institutions, like:
- University of Veterinary Medicine and Pharmacy, Slovakia
- University of Pennsylvania, USA
- Royal GD, the Netherlands
- Istituto Zooprofilattico Sperimentale della Venezie, Italy
- Kimron Veterinary Institute, Israel
- The University of Melbourne, Australia
- ANSES, France

We have several industry partners, like:
- Bioproperties Pty LtD., Australia
- Huvepharma NV, Belgium
- CEVA Sante Animale, France
- BioChek BV, the Netherlands
- FarmPharma, Sweden

STARTUP

We opened MolliScience Ltd., our Startup company specialised on Mycoplasma diagnostic & biotech services. We turn our know-how and fundamental research results into application. We develop In Vitro Diagnostics (IVD) under our own brand and we run vaccine invention research projects.