Magendira Mani Vinayagam

Scopus Publications

Naringin modulates the impairment of memory, anxiety, locomotor, and emotionality behaviors in rats exposed to deltamethrin; a possible mechanism association with oxidative stress, acetylcholinesterase and ATPase
Vinayagam Magendira Mani, Abdul Majeeth Mohamed Sadiq
Biomedicine and Preventive Nutrition, 2014
Diallyl sulfide attenuates renal injury by altering the expressions of COX-2 and NF-κB during cisplatin-induced nephrotoxicity in male wistar rats
Arunkumar Jagadeesan, Magendira Mani Vinayagam, Prakash Dharmalingam
Biomedicine and Preventive Nutrition, 2014
A dietary flavanone glycoside naringin modulates the abnormalities of human erythrocytes exposed with deltamethrin, by upregulating the expression of antioxidants
Vinayagam Magendira Mani, Adikesavan Gokulakrishnan, Abdul Majeet Mohammed Sadiq
Biomedicine and Preventive Nutrition, 2014
Pyrethroid deltamethrin-induced developmental neurodegenerative cerebral injury and ameliorating effect of dietary glycoside naringin in male wistar rats
Vinayagam Magendira Mani, Sivaji Asha, Abdul Majeeth Mohamed Sadiq
Biomedicine and Aging Pathology, 2014
Ameliorating effect of Phoenix dactylifera on lambda cyhalothrin induced biochemical, hematological and hepatopathological alterations in male wistar rats
Mani Ramadhas, Krishnan Palanisamy, Munisamy Sudhagar, Vinayagam Magendira Mani
Biomedicine and Aging Pathology, 2014
(-)-Epigallocatechin-gallate (EGCG) stabilize the mitochondrial enzymes and inhibits the apoptosis in cigarette smoke-induced myocardial dysfunction in rats
Gokulakrishnan Adikesavan, Magendira Mani Vinayagam, Liyakath Ali Abdulrahman, Thirunavukkarasu Chinnasamy
Molecular Biology Reports, 2013
S-allylcysteine attenuates renal injury by altering the expressions of iNOS and matrix metallo proteinase-2 during cyclosporine-induced nephrotoxicity in Wistar rats
Vinayagam Magendiramani, Syed Umesalma, Srinivasan Kalayarasan, Ponnuraj Nagendraprabhu, Jagadeesan Arunkumar, Ganapasam Sudhandiran
Journal of Applied Toxicology, 2009
Cyclosporine A (CsA) is the first choice immunosuppressant used for the prevention of allograft rejection in solid organ transplantation and immune‐mediated diseases. Reactive oxygen species‐induced oxidative stress and lipid peroxidation are implicated in the pathophysiology of CsA‐induced renal injury. In this work, we have studied the effect of a garlic‐derived compound, S‐allylcysteine (SAC) on CsA‐induced nephrotoxicity. CsA‐induced nephrotoxicity was assessed in terms of increased activities of serum marker enzymes and levels of kidney markers. CsA administration induced significant elevation in lipid peroxidation along with abnormal levels of enzymic and non‐enzymic antioxidants in the kidneys of the rats. SAC administration improved renal function by bringing about a significant decrease in peroxidative levels and increase in antioxidant status. Elevated expressions of inducible nitric oxide synthase (iNOS) and nuclear factor kappa B (NF‐κB) due to CsA administration were reduced by SAC treatment. An increase in the expression of matrix metalloproteinase‐2 (MMP‐2) was evident in CsA‐induced groups of rats, which was moderately reduced in SAC treated rats. An increase in the levels of serum constituent's urea, uric acid and creatinine was observed in the CsA‐induced rats, which was reduced upon treatment with SAC. These results indicate that SAC has a protective action against CsA‐induced nephrotoxicity which is also supported by histopathological studies. A comparative study of the antioxidant vitamin C and SAC is more valuable to assess the efficacy of the drug that can be used for the treatment of nephrotoxicity. Copyright © 2009 John Wiley & Sons, Ltd.

RECENT SCHOLAR PUBLICATIONS

ADVANCES IN PHYTOMEDICINE AND THERAPEUTIC APPROACHES FOR EMERGING FRONTIERS IN BREAST CANCER
SMMM Vinayagam
BIOLOGICAL SCIENCES TODAY: EMERGING DISCOVERIES AND APPLICATION 1, 29-36 , 2025
2025
The Herbalist’s Handbook: A Guide to Medicinal Plants and Healing Teas
M Mani
MKJC 1, 1-115 , 2024
2024
Exploring the connection Between Mobile Phone Exposure and Child Health: An In-depth Review of Physical, Cognitive, and Psychosocial Effects
M Mani
Shodha-Prabha 48 (02), 327-334 , 2023
2023
Exploring the Nexus of Eating, Sleeping Habits and Health Issues Among College Students: A Comprehensive Review
M Mani
Shodha-Prabha 48 (02), 342-348 , 2023
2023
Balancing Acts: A Comprehensive Review of Physical and Mental Health Management Strategies for Working Women
M Mani
Shodha-Prabha 48 (02), 44-50 , 2023
2023
Practical Manual for Biological Chemistry
M Mani
2023
Practical Manual for Nutritional Biochemistry
M Mani
2023
An AI Based Approach for diagnosis of dental caries – A Comprehensive Review
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development … , 2023
2023
A Healing Touch: The Role of Nanoparticles and Artificial Intelligence in Wound Healing - A Comprehensive Review of AI in Healing Research
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development … , 2023
2023
AI-Enhanced Insights in Bone Remodeling Science: A Comprehensive Review of Research and Applications
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development … , 2023
2023
Revolutionizing Resource Recovery: A Profound Examination of AI-Powered Troubleshooting in Petroleum and Chemical Engineering Drilling Operations
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development … , 2023
2023
Preparing HR for the Future: AI-driven Skills Development and training initiatives in Life Sciences
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development … , 2023
2023
Unleashing Potential: Empowering Women Entrepreneurs to Drive Transformation and Overcome Barriers in India
M Mani
International Conference on Breaking Barriers and Empowering Changes in … , 2023
2023
An AI Based Approach for diagnosis of dental caries – A Comprehensive Review
M Mani
Preparing HR for the Future: AI-driven Skills Development and training … , 2023
2023
A Healing Touch: The Role of Nanoparticles and Artificial Intelligence in Wound Healing - A Comprehensive Review of AI in Healing Research
M Mani
Preparing HR for the Future: AI-driven Skills Development and training … , 2023
2023
AI-Enhanced Insights in Bone Remodeling Science: A Comprehensive Review of Research and Applications
M Mani
Preparing HR for the Future: AI-driven Skills Development and training … , 2023
2023
Revolutionizing Resource Recovery: A Profound Examination of AI-Powered Troubleshooting in Petroleum and Chemical Engineering Drilling Operations
M Mani
Preparing HR for the Future: AI-driven Skills Development and training … , 2023
2023
Preparing HR for the Future: AI-driven Skills Development and training initiatives in Life Sciences
M Mani
Preparing HR for the Future: AI-driven Skills Development and training … , 2023
2023
Protective effect of vitamin C on deltamerhrin induced oxidative stress in human erythrocytes-An in vitro study
AA Hussain, K Vinoth, VM Mani
Int J Sci Human 4 (1), 26-39 , 2018
2018
Citations: 3
Protective Effect of Flavonoid Naringin on Lambda cyhalothrin Induced Haematological and Hepato-Pathological Variations in Male Wistar Rats
DA Abdulrahman Liyakath Ali*, Vinayagam Magendira Mani, Adhikesaven ...
Hematological Diseases and Therapies 2 (2), 1-9 , 2017
2017
Citations: 6

MOST CITED SCHOLAR PUBLICATIONS

Pyrethroid deltamethrin-induced developmental neurodegenerative cerebral injury and ameliorating effect of dietary glycoside naringin in male wistar rats
VM Mani, S Asha, AMM Sadiq
Biomedicine & Aging Pathology 4 (1), 1-8 , 2014
2014.0
Citations: 38
(−)-Epigallocatechin-gallate (EGCG) stabilize the mitochondrial enzymes and inhibits the apoptosis in cigarette smoke-induced myocardial dysfunction in rats
G Adikesavan, MM Vinayagam, LA Abdulrahman, T Chinnasamy
Molecular biology reports 40 (12), 6533-6545 , 2013
2013.0
Citations: 36
Naringin modulates the impairment of memory, anxiety, locomotor, and emotionality behaviors in rats exposed to deltamethrin; a possible mechanism association with oxidative …
VM Mani, AMM Sadiq
Biomedicine & Preventive Nutrition 4 (4), 527-533 , 2014
2014.0
Citations: 34
Antioxidant Activity of Euphorbia hirta Linn Leaves Extracts
VMMAMS S. Asha, P. Thirunavukkarasu
European Journal of Medicinal Plants 14 (1), 1-14 , 2016
2016.0
Citations: 31
S‐ allylcysteine attenuates renal injury by altering the expressions of iNOS and matrix metallo proteinase‐2 during cyclosporine‐induced nephrotoxicity in Wistar rats
V Magendiramani, S Umesalma, S Kalayarasan, P Nagendraprabhu, ...
Journal of Applied Toxicology 29 (6), 522-530 , 2009
2009.0
Citations: 25
Ameliorating effect of Phoenix dactylifera on lambda cyhalothrininduced biochemical, hematological and hepatopathologicalalterations in male wistar rats
VMM Mani Ramadhas , Krishnan Palanisamy , Munisamy Sudhagar
Biomedicine & Aging Pathology 2014, 7 , 2014
2014.0
Citations: 13
Molecular Mechanism of Neurodevelopmental Toxicity Risks of Occupational Exposure of Pyrethroid Pesticide with Reference to Deltamethrin - A Critical Review
AGAMMS Vinayagam Magendira Mani1
BAOJ Pathology 1 (2), 1-14 , 2017
2017.0
Citations: 8
Flavonoid naringin inhibits microglial activation and exerts neuroprotection against deltamethrin induced neurotoxicity through Nrf2/ARE signaling in the cortex and hippocampus …
M Sadiq
World Journal of Pharmaceutical Sciences 3 (12), 2410-2426 , 2015
2015.0
Citations: 7
Protective Effect of Flavonoid Naringin on Lambda cyhalothrin Induced Haematological and Hepato-Pathological Variations in Male Wistar Rats
DA Abdulrahman Liyakath Ali*, Vinayagam Magendira Mani, Adhikesaven ...
Hematological Diseases and Therapies 2 (2), 1-9 , 2017
2017.0
Citations: 6
Diallyl sulfide attenuates renal injury by altering the expressions ofCOX-2 and NF- B during cisplatin-induced nephrotoxicity in malewistar rats
M mani
Biomedicine and Preventive nutrition 4 (4), 291-297 , 2014
2014.0
Citations: 5
Protective effect of vitamin C on deltamerhrin induced oxidative stress in human erythrocytes-An in vitro study
AA Hussain, K Vinoth, VM Mani
Int J Sci Human 4 (1), 26-39 , 2018
2018.0
Citations: 3
protective effect of pomegranate peel extract on mosquito coil smoke exposed alveolar damage in male Wistar rats
K Vinoth, VM Mani, AL Ali
International Journal of Science and Humanities 2, 417-430 , 2016
2016.0
Citations: 3
Pyrethroid deltamethrin induced haematological and hepato-pathological impairment in male Wistar rats and potential attenuation by flavonoid naringin
AGAMS V. Magendira Mani†, A. Liyakath Ali†
International Journal of Science and Humanities 1 (1), 623-640 , 2015
2015.0
Citations: 3
Attenuation of Cypermethrin Induced Nephrotoxicity by (-) Epigallocatechin Gallate (EGCG) in Male Wistar Rats
AGALA K. Vinoth, V. Magendira Mani
International Journal of Science and Humanities 1 (1), 665-684 , 2015
2015.0
Citations: 3
WITHDRAWN: Attenuation of cardiac oxidative stress by (−)-epigallocatechin-gallate (EGCG) in CS exposed rats
A Gokulakrisnan, MM Vinayagam, LAA Rahman, C Thirunavukkarasu
Biomedicine & Pharmacotherapy , 2010
2010.0
Citations: 3
Hepatoprotective effect of quercetin on lambdacyhalothrin induced hepatotoxicity in male Wistar rats
VM Mani, AN Ahmed, AL Ali, A Gokulakrishnan, K Vinoth, AA Hussain
Int. J. Sci. Humanit 2, 401-416 , 2016
2016.0
Citations: 2
A dietary flavanone glycoside naringin modulates the abnormalities of human erythrocytes exposed with deltamethrin, by upregulating the expression of antioxidants
VM Mani, A Gokulakrishnan, AMM Sadiq
Biomedicine & Preventive Nutrition 4 (2), 265-270 , 2014
2014.0
Citations: 2
Ameliorating effects of Phoenix dactylifera on sub-chronic exposure of mosquito coil smoke induced biochemical and pulmonary alveolar impairment in male Wistar rats
M Sudhagar, R Karthick, M Nanthakumar, VM Mani
Science and Humanities 609 , 0
Citations: 1
ADVANCES IN PHYTOMEDICINE AND THERAPEUTIC APPROACHES FOR EMERGING FRONTIERS IN BREAST CANCER
SMMM Vinayagam
BIOLOGICAL SCIENCES TODAY: EMERGING DISCOVERIES AND APPLICATION 1, 29-36 , 2025
2025.0
The Herbalist’s Handbook: A Guide to Medicinal Plants and Healing Teas
M Mani
MKJC 1, 1-115 , 2024
2024.0