Magendira Mani Vinayagam
@apcas.ac.in
ASSIATANAT PROFESSOR OF BIOCHEMISTRY
Adhiparasakthi College of Arts and Science
7
Scopus Publications
199
Scholar Citations
6
Scholar h-index
6
Scholar i10-index
Scopus Publications
- Naringin modulates the impairment of memory, anxiety, locomotor, and emotionality behaviors in rats exposed to deltamethrin; a possible mechanism association with oxidative stress, acetylcholinesterase and ATPase
Vinayagam Magendira Mani and Abdul Majeeth Mohamed Sadiq
Elsevier BV - A dietary flavanone glycoside naringin modulates the abnormalities of human erythrocytes exposed with deltamethrin, by upregulating the expression of antioxidants
Vinayagam Magendira Mani, Adikesavan Gokulakrishnan, and Abdul Majeet Mohammed Sadiq
Elsevier BV - Diallyl sulfide attenuates renal injury by altering the expressions of COX-2 and NF-κB during cisplatin-induced nephrotoxicity in male wistar rats
Arunkumar Jagadeesan, Magendira Mani Vinayagam, and Prakash Dharmalingam
Elsevier BV - Ameliorating effect of Phoenix dactylifera on lambda cyhalothrin induced biochemical, hematological and hepatopathological alterations in male wistar rats
Mani Ramadhas, Krishnan Palanisamy, Munisamy Sudhagar, and Vinayagam Magendira Mani
Elsevier BV - Pyrethroid deltamethrin-induced developmental neurodegenerative cerebral injury and ameliorating effect of dietary glycoside naringin in male wistar rats
Vinayagam Magendira Mani, Sivaji Asha, and Abdul Majeeth Mohamed Sadiq
Elsevier BV - (-)-Epigallocatechin-gallate (EGCG) stabilize the mitochondrial enzymes and inhibits the apoptosis in cigarette smoke-induced myocardial dysfunction in rats
Gokulakrishnan Adikesavan, Magendira Mani Vinayagam, Liyakath Ali Abdulrahman, and Thirunavukkarasu Chinnasamy
Springer Science and Business Media LLC - S-allylcysteine attenuates renal injury by altering the expressions of iNOS and matrix metallo proteinase-2 during cyclosporine-induced nephrotoxicity in Wistar rats
Vinayagam Magendiramani, Syed Umesalma, Srinivasan Kalayarasan, Ponnuraj Nagendraprabhu, Jagadeesan Arunkumar, and Ganapasam Sudhandiran
Wiley
Cyclosporine A (CsA) is the first choice immunosuppressant used for the prevention of allograft rejection in solid organ transplantation and immune‐mediated diseases. Reactive oxygen species‐induced oxidative stress and lipid peroxidation are implicated in the pathophysiology of CsA‐induced renal injury. In this work, we have studied the effect of a garlic‐derived compound, S‐allylcysteine (SAC) on CsA‐induced nephrotoxicity. CsA‐induced nephrotoxicity was assessed in terms of increased activities of serum marker enzymes and levels of kidney markers. CsA administration induced significant elevation in lipid peroxidation along with abnormal levels of enzymic and non‐enzymic antioxidants in the kidneys of the rats. SAC administration improved renal function by bringing about a significant decrease in peroxidative levels and increase in antioxidant status. Elevated expressions of inducible nitric oxide synthase (iNOS) and nuclear factor kappa B (NF‐κB) due to CsA administration were reduced by SAC treatment. An increase in the expression of matrix metalloproteinase‐2 (MMP‐2) was evident in CsA‐induced groups of rats, which was moderately reduced in SAC treated rats. An increase in the levels of serum constituent's urea, uric acid and creatinine was observed in the CsA‐induced rats, which was reduced upon treatment with SAC. These results indicate that SAC has a protective action against CsA‐induced nephrotoxicity which is also supported by histopathological studies. A comparative study of the antioxidant vitamin C and SAC is more valuable to assess the efficacy of the drug that can be used for the treatment of nephrotoxicity. Copyright © 2009 John Wiley & Sons, Ltd.
RECENT SCHOLAR PUBLICATIONS
- Exploring the connection Between Mobile Phone Exposure and Child Health: An In-depth Review of Physical, Cognitive, and Psychosocial Effects
M Mani
Shodha-Prabha 48 (02), 327-334 2023 - Exploring the Nexus of Eating, Sleeping Habits and Health Issues Among College Students: A Comprehensive Review
M Mani
Shodha-Prabha 48 (02), 342-348 2023 - Balancing Acts: A Comprehensive Review of Physical and Mental Health Management Strategies for Working Women
M Mani
Shodha-Prabha 48 (02), 44-50 2023 - Practical Manual for Biological Chemistry
M Mani
2023 - Practical Manual for Nutritional Biochemistry
M Mani
2023 - An AI Based Approach for diagnosis of dental caries – A Comprehensive Review
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development 2023 - A Healing Touch: The Role of Nanoparticles and Artificial Intelligence in Wound Healing - A Comprehensive Review of AI in Healing Research
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development 2023 - AI-Enhanced Insights in Bone Remodeling Science: A Comprehensive Review of Research and Applications
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development 2023 - Revolutionizing Resource Recovery: A Profound Examination of AI-Powered Troubleshooting in Petroleum and Chemical Engineering Drilling Operations
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development 2023 - Preparing HR for the Future: AI-driven Skills Development and training initiatives in Life Sciences
M Mani
ICSSR sponsored Preparing HR for the Future: AI-driven Skills Development 2023 - Protective effect of vitamin C on deltamerhrin induced oxidative stress in human erythrocytes-An in vitro study
AA Hussain, K Vinoth, VM Mani
Int J Sci Human 4 (1), 26-39 2018 - Protective Effect of Flavonoid Naringin on Lambda cyhalothrin Induced Haematological and Hepato-Pathological Variations in Male Wistar Rats
DA Abdulrahman Liyakath Ali*, Vinayagam Magendira Mani, Adhikesaven ...
Hematological Diseases and Therapies 2 (2), 1-9 2017 - Molecular Mechanism of Neurodevelopmental Toxicity Risks of Occupational Exposure of Pyrethroid Pesticide with Reference to Deltamethrin - A Critical Review
AGAMMS Vinayagam Magendira Mani1
BAOJ Pathology 1 (2), 1-14 2017 - Protective Effect of Flavonoid Naringin on Lambda cyhalothrin Induced Haematological and Hepato-Pathological Variations in Male Wistar Rats
AL Ali, VM Mani, A Gokulakrishnan, D Alagesan
Hematological Diseases and Therapies 17 (2) 2017 - Antioxidant Activity of Euphorbia hirta Linn Leaves Extracts
VMMAMS S. Asha, P. Thirunavukkarasu
European Journal of Medicinal Plants 14 (1), 1-14 2016 - Hepatoprotective effect of quercetin on lambdacyhalothrin induced hepatotoxicity in male Wistar rats
VM Mani, AN Ahmed, AL Ali, A Gokulakrishnan, K Vinoth, AA Hussain
Int. J. Sci. Humanit 2, 401-416 2016 - protective effect of pomegranate peel extract on mosquito coil smoke exposed alveolar damage in male Wistar rats
K Vinoth, VM Mani, AL Ali
International Journal of Science and Humanities 2, 417-430 2016 - Flavonoid naringin inhibits microglial activation and exerts neuroprotection against deltamethrin induced neurotoxicity through Nrf2/ARE signaling in the cortex and hippocampus
M Sadiq
World Journal of Pharmaceutical Sciences 3 (12), 2410-2426 2015 - Ameliorating effects of Phoenix dactylifera on sub-chronic exposure of mosquito coil smoke induced biochemical and pulmonary alveolar impairment in male Wistar rats
MNVMM M. Sudhagar, R. Karthick
International Journal of Science and Humanities 1 (1), 609-622 2015 - Pyrethroid deltamethrin induced haematological and hepato-pathological impairment in male Wistar rats and potential attenuation by flavonoid naringin
AGAMS V. Magendira Mani†, A. Liyakath Ali†
International Journal of Science and Humanities 1 (1), 623-640 2015
MOST CITED SCHOLAR PUBLICATIONS
- Naringin modulates the impairment of memory, anxiety, locomotor, and emotionality behaviors in rats exposed to deltamethrin; a possible mechanism association with oxidative
VM Mani, AMM Sadiq
Biomedicine & Preventive Nutrition 4 (4), 527-533 2014
Citations: 36 - (−)-Epigallocatechin-gallate (EGCG) stabilize the mitochondrial enzymes and inhibits the apoptosis in cigarette smoke-induced myocardial dysfunction in rats
G Adikesavan, MM Vinayagam, LA Abdulrahman, T Chinnasamy
Molecular biology reports 40, 6533-6545 2013
Citations: 35 - Pyrethroid deltamethrin-induced developmental neurodegenerative cerebral injury and ameliorating effect of dietary glycoside naringin in male wistar rats
VM Mani, S Asha, AMM Sadiq
Biomedicine & Aging Pathology 4 (1), 1-8 2014
Citations: 30 - Antioxidant Activity of Euphorbia hirta Linn Leaves Extracts
VMMAMS S. Asha, P. Thirunavukkarasu
European Journal of Medicinal Plants 14 (1), 1-14 2016
Citations: 27 - S‐allylcysteine attenuates renal injury by altering the expressions of iNOS and matrix metallo proteinase‐2 during cyclosporine‐induced nephrotoxicity in Wistar rats
V Magendiramani, S Umesalma, S Kalayarasan, P Nagendraprabhu, ...
Journal of Applied Toxicology 29 (6), 522-530 2009
Citations: 25 - Ameliorating effect of Phoenix dactylifera on lambda cyhalothrininduced biochemical, hematological and hepatopathologicalalterations in male wistar rats
VMM Mani Ramadhas , Krishnan Palanisamy , Munisamy Sudhagar
Biomedicine & Aging Pathology 2014, 7 2014
Citations: 10 - Flavonoid naringin inhibits microglial activation and exerts neuroprotection against deltamethrin induced neurotoxicity through Nrf2/ARE signaling in the cortex and hippocampus
M Sadiq
World Journal of Pharmaceutical Sciences 3 (12), 2410-2426 2015
Citations: 6 - Molecular Mechanism of Neurodevelopmental Toxicity Risks of Occupational Exposure of Pyrethroid Pesticide with Reference to Deltamethrin - A Critical Review
AGAMMS Vinayagam Magendira Mani1
BAOJ Pathology 1 (2), 1-14 2017
Citations: 5 - Diallyl sulfide attenuates renal injury by altering the expressions ofCOX-2 and NF- B during cisplatin-induced nephrotoxicity in malewistar rats
M mani
Biomedicine and Preventive nutrition 4 (4), 291-297 2014
Citations: 5 - WITHDRAWN: Attenuation of cardiac oxidative stress by (−)-epigallocatechin-gallate (EGCG) in CS exposed rats
A Gokulakrisnan, MM Vinayagam, LAA Rahman, C Thirunavukkarasu
Biomedicine & Pharmacotherapy 2010
Citations: 4 - Protective effect of vitamin C on deltamerhrin induced oxidative stress in human erythrocytes-An in vitro study
AA Hussain, K Vinoth, VM Mani
Int J Sci Human 4 (1), 26-39 2018
Citations: 3 - Protective Effect of Flavonoid Naringin on Lambda cyhalothrin Induced Haematological and Hepato-Pathological Variations in Male Wistar Rats
AL Ali, VM Mani, A Gokulakrishnan, D Alagesan
Hematological Diseases and Therapies 17 (2) 2017
Citations: 3 - Attenuation of Cypermethrin Induced Nephrotoxicity by (-) Epigallocatechin Gallate (EGCG) in Male Wistar Rats
AGALA K. Vinoth, V. Magendira Mani
International Journal of Science and Humanities 1 (1), 665-684 2015
Citations: 3 - Hepatoprotective effect of quercetin on lambdacyhalothrin induced hepatotoxicity in male Wistar rats
VM Mani, AN Ahmed, AL Ali, A Gokulakrishnan, K Vinoth, AA Hussain
Int. J. Sci. Humanit 2, 401-416 2016
Citations: 2 - Pyrethroid deltamethrin induced haematological and hepato-pathological impairment in male Wistar rats and potential attenuation by flavonoid naringin
AGAMS V. Magendira Mani†, A. Liyakath Ali†
International Journal of Science and Humanities 1 (1), 623-640 2015
Citations: 2 - protective effect of pomegranate peel extract on mosquito coil smoke exposed alveolar damage in male Wistar rats
K Vinoth, VM Mani, AL Ali
International Journal of Science and Humanities 2, 417-430 2016
Citations: 1 - A dietary flavanone glycoside naringin modulates the abnormalities of human erythrocytes exposed with deltamethrin, by upregulating the expression of antioxidants
VM Mani, A Gokulakrishnan, AMM Sadiq
Biomedicine & Preventive Nutrition 4 (2), 265-270 2014
Citations: 1 - Ameliorating effects of Phoenix dactylifera on sub-chronic exposure of mosquito coil smoke induced biochemical and pulmonary alveolar impairment in male Wistar rats
M Sudhagar, R Karthick, M Nanthakumar, VM Mani
Science and Humanities 609
Citations: 1