Dr Mahesh Mukund Deshpande

@amrutpharm.co.in

Professor, Department of Pharmaceutical Quality Assurance
Amrutvahini College of Pharamcy,Sangamner

Dr Mahesh Mukund Deshpande


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https://researchid.co/maheshdeshpande83

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmaceutical Science, Analytical Chemistry, Pharmacology, Toxicology and Pharmaceutics
13

Scopus Publications

157

Scholar Citations

6

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Simultaneous Estimation of Pregabalin and Duloxetine, Used to Treat Nerve Pain, by Stability Indicating RP-HPLC Method Using the QBD Approach
    Vaishnavi A. Gosavi, Mahesh M. Deshpande, Gauri D. Ghangale, Machindra J. Chavan
    Current Pharmaceutical Analysis, 2025
    Objective: A novel stability indicating RP-HPLC method was developed and validated for the simultaneous estimation of Pregabalin and Duloxetine by using the QBD approach. Methods: To determine the optimal parameters for the duloxetine and pregabalin study, we used Design Expert version 13.0 in this work. The mobile phase consisted of 0.8 ml/min of methanol: water (80:20, v/v) with o-phosphoric acid-adjusted pH 3.A 250 mm × 4.6 mm ID, 5 μm particle size Cosmosil C18 column was used. The UV-3000-M detector was used to detect at 218 nm. Results: Duloxetine's retention time was 7.153 ± 0.1 min, whereas Pregabalin's was 4.481±0.1 min. The ICH parameters like linearity, accuracy, robustness, ruggedness, LOD and LOQ, and system suitability were determined. Likewise, the tailing factors were found to be 1.27 and 1.26, while the theoretical plates of duloxetine and pregabalin were found to be 8313 and 8549, respectively. The recovery study shows the results (99.37–99.84% for pregabalin and 99.03–99.74% for duloxetine), and the precision was obtained with a %RSD of less than 2%. The result of the assay was 99.92 % for pregabalin and 99.39% for duloxetine. The developed method was used for the forced degradation study. The Box-Behnken design experiment using Design Expert 13.0 was adopted for the QBD approach. Conclusion: All the values obtained for different parameters were within the acceptable range of ICH. The developed method can be routinely used for the simultaneous estimation of Pregabalin and Duloxetine by using the QBD approach.
  • Simultaneous UV-Spectrophotometric Estimation of Aceclofenac and Cyclobenzaprine HCl by three different methods
    Mahesh Mukund Deshpande, Machindra Jayram Chavan
    Research Journal of Pharmacy and Technology, 2024
    Background: An Aceclofenac and Cyclobenzaprine HCl is NSAID and antidipressive agent, a rare combination. Objective: The aim was to develop and validate new UV-spectrophotometric methods. Method: In first method (M-I) simultaneous estimation with forced degradation was performed. In second method (M-II) simultaneous estimation by derivatization technique was performed. In third method (M III) the simple simultaneous estimation was performed. The abbreviations ACE and CYC are used for Aceclofenac and Cyclobenzaprine HCl in the current manuscript. Results: In method I, the linearity range was obtained as 5 - 25µg/ml with correlation coefficient 1 respectively. The results were 99.45% 99.50% 99.97% 99.78% 99.36% 99.67% respectively for both the drugs. The forced degradation for both drugs by applying the method was carried out. In method II, the derivatization with 2% ninhydrin was carried out. The correlation coefficient was obtained as 1 for both the drugs respectively. The recovery study values were obtained as 95.60%, 95.95%, and 95.53% 95.85% 98.82% 98.33% respectively for both the drugs. In the method III, the correlation coefficient of both the drugs was 1. The recovery study values were obtained as 99.56-100.32% 99.05 – 100.2% for both drugs respectively. Conclusion: All values were obtained in the acceptable range of as per ICH guidelines. The forced degradation was useful to obtain stability indicating data for this combination. The derivatization technique is first time used for the analysis of this combination. The one-way analysis of variance (ANNOVA) shows no significant difference among these three methods. As no methods are available for this new and recent combination, these methods can be routinely used for the analysis of these drugs.
  • Ayurvedic treatment of a case diagnosed as AIDS and diffuse large B cell lymphoma - Case report
    Upendra Dixit, Shashirekha H. K., Sushant Sukumar Bargale, Asmita Gaikwad, Mahesh Deshpande, Harshal Tare
    Multidisciplinary Science Journal, 2023
    Non-Hodgkin's lymphoma (NHL) is recognized as the most common form of lymphoma. Among the various subtypes of NHL, diffuse large B-cell lymphoma (DLBCL) stands out as the predominant type, constituting approximately 30 percent of all lymphomas. DLBCL has an annual incidence rate of 2.9 per 100,000 in men and 1.5 per 100,000 in women in India. It is a rapidly growing and aggressive form of NHL. A 40-year-old male patient presented with a chief complaint of abdominal pain and discomfort persisting for 4-5 months. The patient had previously been diagnosed with AIDS (Acquired immune deficiency syndrome - a retroviral disease) and non-Hodgkin's lymphoma Diffuse Large B-Cell Lymphoma (DLBCL) on 29-04-14. Ileal resection had already been performed on 20-01-2014, and the patient received the initial cycle of CHOP (cyclophosphamide, doxorubicin [Adriamycin], vincristine [Oncovin], prednisolone) chemotherapy on 02-04-14. The MIB index was measured at 70%. The report on 22-04-14 indicated the presence of a few enlarged lymph nodes scattered in the mesentery and paraaortic regions. The patient declined further cycles of chemotherapy. Based on Ayurvedic diagnosis, the patient initially exhibited symptoms resembling Arsha (hemorrhoids) and Gulma (tumor), followed by Grahani Daurbalya (improper digestion). At the time of examination, he had severe Pandu. Considering the pathology and symptomatology, a prescription of Heeraka Bhasma + Chaturmukha Rasa, Triphala + Kapardika Bhasma + Panchamrita Parpati + Patola (Trichosanthus cucmerina) + Dhanvayasa (fegoniacretica), TapyadiLoha + Navyasootashekhara + Vanga + Asthimajja Pachaka (Guduchi + Amalaki + Musta) + Kukkutanakhi (Tectaria coadunate) along with 10 ml of Rohitakarishta and Krimikuthara Rasa was prescribed. After seven months of treatment, the symptoms subsided. No adverse events were reported during the seven-month treatment and follow-up period. In conclusion, this case study demonstrates the safe and effective treatment of these diseases using Ayurveda. It improved the patient's health and quality of life, resolving the issue of swollen lymph nodes. The patient survived for over four years thereafter.
  • Design, Development and Characterization of Econazole loaded Nanoparticles for Topical Application
    Sufiyan Ahmad, Khushabu Patil, Ganaraj Koli, Bakhshi A. Rahman, Lokesh Barde, Mahesh Deshpande, Harshal Tare
    International Journal of Pharmaceutical Quality Assurance, 2023
    Background and Objectives: Econazole nitrate (ECN) loaded nanoparticles with topical administration were the focus of the current study, which aimed to improve the topical efficacy of the medicine in treating fungal infections while also mitigating the drug’s gastrointestinal (GI) side effects. Further colloidal carrier methodology was employed as a method for the topical administration of medications with precision. Method: The emulsification-diffusion (E-D) method is an alternate approach for preparing nanogels that avoids the toxicitysolvent issues associated with the emulsification-evaporation technique. Its ease of use, enhanced stability, and adaptability have all been verified by a variety of research groups. ECN loaded with dichloromethane in stabilizer solution, formulated by high-speed homogenization at elevated pressure. The addition of aqueous phase with repeated homogenization cycles causes drug diffusion into nanogels. Further addition of mannitol as cryoprotectant and Carbapol 940 as gelling agent stabiles the formulation. Results: The typical size of the particles, polydispersity index (PDI), and zeta potential were all measured with the use of the Malvern zetasizer. Of the five NFs, the lyophilized batch of NF3 exhibited the lowest zeta potential (-11.6 mV) and the PDI (0.208), indicating that the composition was stable. DSC and XRD analysis revealed an amorphous transformation of ECN. The scanning electron micrograph demonstrated discrete, roundish particles. The existence, viscosity, and spreading ability of a gelled dispersion of the selected NLCs were evaluated. Total od 77% of the medication was released in-vitro from a chosen formulation of ECN-loaded nanogels. As a result, it is reasonable to assume that ECN-loaded nanogels are an effective drug delivery system for treating fungal infections since they prolong the duration of drug release. Conclusion: Under degraded conditions, there are not any peaks that conflict with one another. As a result, a technique was developed that is highly applicable due to its sensitivity, strength, accuracy, and demonstration of stability.
  • Stability indicating HPLC method development and validation of Fostemsavir in bulk and marketed formulations by implementing QbD approach
    Mahesh Deshpande, Sejal Barge, Khushabu Patil, Asmita Gaikwad, Lokesh Barde, Nitin Deshmukh
    International Journal of Experimental Research and Review, 2023
    Background: Achieving a predictable degree of quality with intended and planned specifications is known as "quality by design." QbD (Quality-by-Design) is an alternative to conventional method development that places more attention on identifying and mitigating potential risks. Component of the Quality-by-Design methodology involves conducting a series of experiments to learn how various factors, including the dependant variables, affect the answers of interest. Here, we use a QbD (Quality-by-Design) loom to detail the creation and verification of a stability-indicating high-performance liquid chromatography (HPLC) method for Fostemsavir in both bulk and finished-goods forms.Results:In this work, we present a workable experimental design for optimising the RP-HPLC separation technique by identifying the optimum mobile phase concentration and flow rate. Below are the ideal chromatographic conditions as calculated by Design Expert version 13.0: Mobile phase: 80 parts acetonitrile to 20 parts formic acid (v/v), flow rate: 0.8 millilitres per minute, retention time: 3.24 minutes, column dimensions: GIST C18 (250 mm × 4.6 mm × 5.0 μm).Here we propose a practical experimental layout for determining the optimal mobile phase concentration and flow rate for the RP-HPLC separation technique. Using Design Expert version 13.0, the optimum chromatographic conditions were determined to be as follows: Shim-pack GIST C18 (250 mm 4.6 mm, 5.0 μ), mobile phase acetonitrile to 1% formic acid (80:20, v/v), flow rate 0.8 ml/min, and retention period 3.24 min.At a detection wavelength of 266 nm, it was discovered that the devised technique was linear over a concentration range of 50-90 μg/ml (r2 = 0.997). Test parameters for the system's appropriateness were determined to be 1.124 for the tailing factor and 9480 for the theoretical plates. Intraday RSD was found to range from 0.70 to 0.94, whereas interday RSD was found to range from 0.55 to 0.95 percent. Values for robustness were under 2%. The solution stability % RSD was calculated to be 0.83. The result of the assay was 100.05 percent. The created methodologies were used to studies of forced degradation, and the stressed materials were analysed. The parameters used to validate the procedure fell within the acceptable range recommended by ICH.Conclusion: Using Design Expert 13.0, we created a central composite design experiment that illustrates the relationships between mobile phase and flow rate across three levels, with retention duration, tailing factor, as well as theoretical plates as the responses of interest. By this work, we gain insight into the variables that affect chromatographic separation and strengthen our conviction that the HPLC method we've devised will serve our needs. Quantitative method development was applied to improve comprehension of multi-tiered method variables.
  • New Stability Indicating RP-HPLC Method for Estimation of the Drug Molnupiravir
    Mahesh Deshpande, Farhat Shaikh, Vijay Sable, Khushabu Patil, Machchhindra R Holam, Harshal Tare
    International Journal of Pharmaceutical Quality Assurance, 2023
    Background: Molnupiravir was granted approval by the UKS medicines and health product regulatory agency on 04 November 2021 and on 23 December 2021, granted emergency use of authorization by FDA. Objective: Provide a technique for measuring Molnupiravir in active pharmaceutical ingredients and formulations. Method: The wavelength maximum was found to be 236 nm. ICH guidelines were followed. The forced degradation study in the form of acidic, alkali, thermal, photolytic, hydrolytic, and oxidative stress conditions was carried out for Molnupiravir. Results: The method was linear, as measured by a coeffi cient of correlation (R2) of 0.9991 in the 10 to 50 μg/mL range. The %RSD for precision, accuracy, limit of detection (LoD), limit of quantitation (LoQ), ruggedness, and robustness was within acceptable limits per ICH Q2 (R1). Conclusion: HPLC equipped with a UV detector is used to create and verify the proposed method. An acetonitrile mobile phase component of 20% was used, demonstrating the more cost-eff ective technique. The extensive data of mobile phase optimization gives a complete idea of fi nal chromatographic conditions, which can be further implemented for future analysis. Molnupiravir shows less than 4% degradation under diff erent stress conditions. The forced degradation data helps show stability, indicating the behavior of Molnupiravir.
  • Development of validated HPTLC and UHPLC methods for quantification of Withanolide in extract and formulation
    Sufiyan Ahmad, Mahendra Ganbase, Nitin Deshmukh, Khushabu Patil, Lokesh Barde, Mahesh Deshpande, Asmita Gaikwad, Pravin Tajane
    International Journal of Experimental Research and Review, 2023
    High performance thin layer chromatography (HPTLC) and Ultra-High-Performance Liquid Chromatography (UHPLC) techniques were developed and validated to quantify Withanolide in extract and formulation. On Al-backed silica gel 60 F254 TLC plates (10 cm × 10 cm, layer thickness 0.2 mm), which had been prewashed with methanol, HPTLC separation was carried out. Dichloromethane: Methanol: Toluene: Acetone in various ratios produced good separation in mobile phase (5:1:1:0.5 v/v). Camag TLC scanner densitometric scanning at 365 nm determined and quantified. This approach produced compact Withanolide spots at Rf 0.48. ICH guidelines verified HPTLC's precision, reproducibility, and accuracy. Withanolide linearity was 500-3000 ng/spot with R2= 0.9994. LOD & LOQ were found to be 9.48 & 28.73 ng respectively. For UHPLC, Cosmosil C18 was used with acetonitrile: water (0.2 % OPA) (70:30, v/v) mobile phase. Flow rate was 1.5 mL/min. Under optimal chromatographic conditions, Withanolide was retained for 5.9 min and detected at 254 nm. ICH guidelines verified UHPLC's precision, repeatability, and accuracy. Withanolide linearity was 10-60 μg/mL with R2= 0.9994. LOD along with LOQ were 0.411 and 1.245 μg. HPTLC and UHPLC procedures utilized for regular quality control and quick screening of active components from plant extracts.
  • Popping balls papaya extract: Preparation of pediatric dosages in therapeutic formulations for therapeutic usage in dengue and malaria
    Hrutuja Wagh, Avinash Bhosale, Vishal Girbane, Shravanee Bhosale, Manish Bhise, Mahesh Deshpande, Piyush Chandra, Rakesh Ranjan
    International Journal of Experimental Research and Review, 2023
    Spherification is a cutting-edge molecular gastronomy method that has just emerged in the realm of food science and technology, and it may be used to produce foods with superior sensory qualities and a high level of consumer acceptance and satisfaction. This method is excellent for making semi-solid spheres with a membrane coating so thin that it is barely discernible when placed in the mouth. This experiment used a simple spherification method to turn papaya extract into popping balls with sodium alginate. Intraventricular haemorrhage is a potentially fatal consequence of thrombocytopenia in the newborn period. Extracts from papaya leaves show promise as a treatment for refractory cases of newborn thrombocytopenia. This research aims to learn how to make popping balls out of papaya extract that are both safe to eat and tasty by adding jaggery as a sweetener. Physical parameters such as pH, viscosity, and stability of the prepared balls were studied in in-vitro, 30-day time frame. The findings revealed that papaya-popping balls are homogeneous and have a low viscosity. The expected drug release was 91%. Papaya popping balls were subjected to a three-month stability study. According to the results, there was no variation in colour, pH, or viscosity during the study. All the particles in the formulation were round so that it may be given to kids as an alternative to oral solid dose forms.
  • Development and validation of RP-HPLC method and forced degradation of powerful bradykinin inhibitor zaltoprofen
    Mahesh M. Deshpande, Veena S. Kasture, Mahalaxmi Mohan, Machhindra J. Chavan
    Current Pharmaceutical Analysis, 2018
  • Correction: Development and validation of bioanalytical method for the determination of valcyclovir HCl in human plasma by Liquid Chromatoghraphy [Eurasian Journal of Analytical Chemistry, 10, 5, (2015) (106-112)]
    Mahesh Mukund Deshpande, Veena Sanjay Kasture, Mahalaxmi Mohan, Sanjay Chaudhari
    Eurasian Journal of Analytical Chemistry, 2018
  • Development and validation of bioanalytical method for the determination of Valcyclovir HCl in human plasma by liquid chromatoghraphy
    Eurasian Journal of Analytical Chemistry, 2015
  • UV spectrophotometric estimation of nitazoxanide in tablet dosage form
    Research Journal of Pharmacy and Technology, 2011
  • Application of HPLC and HPTLC for the simultaneous determination of cefixime trihydrate and ambroxol hydrochloride in pharmaceutical dosage form
    Eurasian Journal of Analytical Chemistry, 2010

RECENT SCHOLAR PUBLICATIONS

  • Simultaneous estimation of pregabalin and duloxetine, used to treat nerve pain, by stability indicating RP-HPLC method using the QBD approach
    VA Gosavi, MM Deshpande, GD Ghangale, MJ Chavan
    Current Pharmaceutical Analysis 20 (8), 833-848 , 2024
    2024
    Citations: 3
  • Analytical Method Development on Impurity Profiling and Category Wise Analytical Perspectives of Antidiabetic Drugs: A Review
    MM Deshpande, MH Bhalerao
    Pharmaceutical Research-Recent Advances and Trends Vol. 3, 141-176 , 2024
    2024
  • Simultaneous UV-Spectrophotometric Estimation of Aceclofenac and Cyclobenzaprine HCl by three different methods
    MM Deshpande, MJ Chavan
    Research Journal of Pharmacy and Technology 17 (3), 1095-1099 , 2024
    2024
    Citations: 3
  • Ayurvedic treatment of a case diagnosed as AIDS and diffuse large B cell lymphoma-Case report
    U Dixit, S HK, SS Bargale, A Gaikwad, M Deshpande, H Tare
    Multidisciplinary Science Journal 5 (4) , 2023
    2023
    Citations: 1
  • Popping balls papaya extract: Preparation of pediatric dosages in therapeutic formulations for therapeutic usage in dengue and malaria
    H Wagh, A Bhosale, V Girbane, S Bhosale, M Bhise, M Deshpande, ...
    Int. J. Exp. Res. Rev 32, 188-194 , 2023
    2023
    Citations: 3
  • New UV Spectrophotometric Method for the Estimation of Molnupiravir used in the treatment of COVID-19
    MDF Shaikh
    The Open COVID Journal 3, 1-9 , 2023
    2023
    Citations: 4
  • New Stability Indicating RP-HPLC Method for Estimation of the Drug Molnupiravir
    HT Mahesh Deshpande1*, Farhat Shaikh1 , Vijay Sable2 , Khushabu Patil3 ...
    IJPQA 14 (1), 149-158 , 2023
    2023
    Citations: 4
  • New Stability Indicating RP-HPLC Method for Estimation of the Drug Molnupiravir
    HT Mahesh Deshpande1*, Farhat Shaikh1, Vijay Sable2, Khushabu Patil3 ...
    International Journal of Pharmaceutical Quality Assurance 14 (1), 149-158 , 2023
    2023
  • Design, development and characterization of econazole loaded nanoparticles for topical application
    S Ahmad, K Patil, G Koli, BA Rahman, L Barde, M Deshpande, H Tare
    Evaluation 12, 15 , 2023
    2023
    Citations: 9
  • Stability indicating HPLC method development and validation of Fostemsavir in bulk and marketed formulations by implementing QbD approach
    M Deshpande, S Barge, K Patil, A Gaikwad, L Barde, N Deshmukh
    Int. J. Exp. Res. Rev 30, 330-343 , 2023
    2023
    Citations: 3
  • Development of validated HPTLC and UHPLC methods for quantification of Withanolide in extract and formulation
    S Ahmad, M Ganbase, N Deshmukh, K Patil, L Barde, M Deshpande, ...
    Int. J. Exp. Res. Rev 30, 375-387 , 2023
    2023
    Citations: 3
  • A Review on Impurity Profiling, Degradation Studies, and Bioanalytical Methods of Anti-diabetic Drugs
    PDP Mahesh M.Deshpande,Madhuri H.Bhalerao
    Journal of Pharmaceutical Research International 34 (34B), 43-71 , 2022
    2022
    Citations: 6
  • WHY USFDA APPROVED HYDROXYCHLOROQUINE?
    MM Deshpande
    WORLD JOURNAL OF ADVANCE HEALTHCARE RESEARCH 5 (5), 151-152 , 2021
    2021
  • CONVALESCENT PLASMA THERAPY CAN PROVE EFFECTIVE AGAINST COVID 19 AFTER TESTING ITS SAFETY AND EFFICACY
    MM Deshpande
    WORLD JOURNAL OF ADVANCE HEALTHCARE RESEARCH 5 (5), 147-150 , 2021
    2021
  • A REVIEW ON COVID 19: RESPONSIBLE FOR WORLDWIDE PANDEMIC
    KNTCMJ Deshpande M. M.*
    WORLD JOURNAL OF ADVANCE HEALTHCARE RESEARCH 4 (6), 70-73 , 2020
    2020
  • DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF DOLUTEGRAVIR SULPHATE
    SPM Mayur Shivaji Gandhare*, Mahesh Mukund Deshpande, Manoj Sanjay Sonawane ...
    IJRAR 7 (4), 946-951 , 2020
    2020
  • Analytical, Bioanalytical, Stability-Indicating Methods: Key Part of Regulatory Submissions
    MM Deshpande
    Analytical Chemistry-Advancement, Perspectives and Applications , 2020
    2020
    Citations: 5
  • A CORONA VIRUS:-ENEMY FOR WORLD
    PS Ghuge, MM Deshpande, MJ Chavan
    2020
  • A REVIEW ON ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ANTICANCER DRUG BY HPLC METHOD
    PR Sanap, MM Deshpande, MD Phatangare, RN Kachave, MJ Chavan
    2020
  • RECENT TRENDS IN IMPURITY PROFILING METHODS USING ANALYTICAL TECHNIQUES
    MD Phatangare, MM Deshpande, PS Sanap, RN Kachave, MJ Chavan
    World Journal of Pharmaceutical Research www. wjpr. net [Internet] 9, 534 , 2020
    2020
    Citations: 1

MOST CITED SCHOLAR PUBLICATIONS

  • Application of HPLC and HPTLC for the simultaneous determination of cefixime trihydrate and ambroxol hydrochloride in pharmaceutical dosage form
    MM Deshpande, VS Kasture, SA Gosavi
    Eurasian J. Anal. Chem 5 (3), 227-238 , 2010
    2010
    Citations: 54
  • Bioanalytical method development and validation: a
    MM Deshpande, VS Kasture, M Mohan, MJ Chavan
    Recent Adv. Anal. Chem 97 , 2019
    2019
    Citations: 23
  • Design, development and characterization of econazole loaded nanoparticles for topical application
    S Ahmad, K Patil, G Koli, BA Rahman, L Barde, M Deshpande, H Tare
    Evaluation 12, 15 , 2023
    2023
    Citations: 9
  • A Review on Impurity Profiling, Degradation Studies, and Bioanalytical Methods of Anti-diabetic Drugs
    PDP Mahesh M.Deshpande,Madhuri H.Bhalerao
    Journal of Pharmaceutical Research International 34 (34B), 43-71 , 2022
    2022
    Citations: 6
  • Microwave assisted synthesis and evaluation of isatinyl thiazole derivatives as anti-Mycobacterium tuberculosis agents and dTDP-rhamnose inhibitors
    RD Dighe, SS Rohom, MM Deshpande, SA Khairnar, CR Mehetre, ...
    IJRPBS 2, 776 , 2011
    2011
    Citations: 6
  • Application of HPLC and HPTLC for the simultaneous determination of cefixime trihydrate trihydrate and ambroxol hydrochloride in pharmaceutical dosage form
    M Deshpande, V Kasture, S Gosavi
    Eurasian Journal Analytical Chemistry 5, 3 , 2010
    2010
    Citations: 6
  • Analytical, Bioanalytical, Stability-Indicating Methods: Key Part of Regulatory Submissions
    MM Deshpande
    Analytical Chemistry-Advancement, Perspectives and Applications , 2020
    2020
    Citations: 5
  • Practical Approach for Development and Validation of Bioanalytical Method: A Review
    SRC Mahesh M Deshpande, Veena S Kasture, Mahalaxmi Mohan
    Inventi Rapid: Pharm Analysis & Quality Assurance 1 (Issue 1), 1-8 , 2016
    2016
    Citations: 5
  • New UV Spectrophotometric Method for the Estimation of Molnupiravir used in the treatment of COVID-19
    MDF Shaikh
    The Open COVID Journal 3, 1-9 , 2023
    2023
    Citations: 4
  • New Stability Indicating RP-HPLC Method for Estimation of the Drug Molnupiravir
    HT Mahesh Deshpande1*, Farhat Shaikh1 , Vijay Sable2 , Khushabu Patil3 ...
    IJPQA 14 (1), 149-158 , 2023
    2023
    Citations: 4
  • Simultaneous Estimation of Aceclofenac and Paracetamol in bulk and combined tablet dosage form and from biological fluid by planar chromatography
    PP Patil, MM Deshpande, VS Kasture, SA Gosavi
    Research J Pharmacy and Technology 3 (4), 1194-1199 , 2010
    2010
    Citations: 4
  • Simultaneous estimation of pregabalin and duloxetine, used to treat nerve pain, by stability indicating RP-HPLC method using the QBD approach
    VA Gosavi, MM Deshpande, GD Ghangale, MJ Chavan
    Current Pharmaceutical Analysis 20 (8), 833-848 , 2024
    2024
    Citations: 3
  • Simultaneous UV-Spectrophotometric Estimation of Aceclofenac and Cyclobenzaprine HCl by three different methods
    MM Deshpande, MJ Chavan
    Research Journal of Pharmacy and Technology 17 (3), 1095-1099 , 2024
    2024
    Citations: 3
  • Popping balls papaya extract: Preparation of pediatric dosages in therapeutic formulations for therapeutic usage in dengue and malaria
    H Wagh, A Bhosale, V Girbane, S Bhosale, M Bhise, M Deshpande, ...
    Int. J. Exp. Res. Rev 32, 188-194 , 2023
    2023
    Citations: 3
  • Stability indicating HPLC method development and validation of Fostemsavir in bulk and marketed formulations by implementing QbD approach
    M Deshpande, S Barge, K Patil, A Gaikwad, L Barde, N Deshmukh
    Int. J. Exp. Res. Rev 30, 330-343 , 2023
    2023
    Citations: 3
  • Development of validated HPTLC and UHPLC methods for quantification of Withanolide in extract and formulation
    S Ahmad, M Ganbase, N Deshmukh, K Patil, L Barde, M Deshpande, ...
    Int. J. Exp. Res. Rev 30, 375-387 , 2023
    2023
    Citations: 3
  • Stability indicating RP-HPLC and UV spectrophotometric method for the estimation of azilsartan medoxomil in bulk and pharmaceutical formulations
    PM Gosavi, MM Deshpande, MJ Chavan, MMM Deshpande
    Int. J. Res. Anal. Rev 7 (3), 500-523 , 2020
    2020
    Citations: 3
  • Development and validation of bioanalytical method for the determination of valcyclovir HCl in human plasma by liquid chromatoghraphy
    MM Deshpande, VS Kasture, M Mohan, S Chaudhari
    Eur. J. Anal. Chem 10, 106-112 , 2015
    2015
    Citations: 3
  • Determination of impurity profile in Rifapentine
    PM Nawale, MM Deshpande, RN Kachve
    Int J Res Eng Sci Manag 3 (9), 155-58 , 2020
    2020
    Citations: 2
  • Development and validation of RP-HPLC method and forced degradation of powerful bradykinin inhibitor zaltoprofen
    MM Deshpande, VS Kasture, M Mohan, MJ Chavan
    Current Pharmaceutical Analysis 14 (6), 604-610 , 2018
    2018
    Citations: 2