Mariana abrahao Bueno Morais

@cnpem.br

Researcher at Brazilian Biorenewables National Laboratory
Brazilian Center for Research in energy and Materials

Mariana abrahao Bueno Morais


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https://researchid.co/marianaabm

RESEARCH, TEACHING, or OTHER INTERESTS

Structural Biology, Physical and Theoretical Chemistry, Biotechnology
765

Scholar Citations

15

Scholar h-index

16

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Conformational gating mechanism for processive catalysis of β (1, 3)-glucans
    GHB Gimenis, JPM Spadeto, FM Colombari, RY Miyamoto, PMR Higasi, ...
    Nature Communications , 2026
    2026
  • A disulfide redox switch mechanism regulates glycoside hydrolase function
    MP Martins, GH Martins, FJ Fuzita, JPM Spadeto, RY Miyamoto, ...
    Nature Communications 17 (1), 45 , 2026
    2026
    Citations: 1
  • Conformational Free Energy Landscape of β-Glucose in the Gas Phase and Aqueous Solution: Energetic, Structural, and Electronic Changes
    Q Liao, MAB Morais, C Rovira, A Nin-Hill
    ACS omega 10 (19), 19903-19911 , 2025
    2025
    Citations: 4
  • Publisher Correction: A metagenomic ‘dark matter’enzyme catalyses oxidative cellulose conversion
    CA Santos, MAB Morais, F Mandelli, EA Lima, RY Miyamoto, PMR Higasi, ...
    Nature 640 (8058), E7-E7 , 2025
    2025
    Citations: 1
  • A metagenomic ‘dark matter’enzyme catalyses oxidative cellulose conversion
    CA Santos, MAB Morais, F Mandelli, EA Lima, RY Miyamoto, PMR Higasi, ...
    Nature 639 (8056), 1076-1083 , 2025
    2025
    Citations: 53
  • Coordinated conformational changes in P450 decarboxylases enable hydrocarbons production from renewable feedstocks
    WC Generoso, AHS Alvarenga, IT Simões, RY Miyamoto, RR Melo, ...
    Nature Communications 16 (1), 945 , 2025
    2025
    Citations: 5
  • Probing enzymatic mechanisms with Density Functional Theory and enhanced sampling methods
    FM Colombari, MAB Morais
    Theoretical and Computational Chemistry 25, 291-301 , 2025
    2025
  • A molecular dynamics study of membrane positioning for 7-transmembrane RGS proteins to modulate G-protein-mediated signaling in plants
    CC Oliveira, EB Simoni, MAB Morais, EPB Fontes, PAB Dos Reis, ...
    Computational and Structural Biotechnology Journal 27, 1529-1537 , 2025
    2025
    Citations: 1
  • A functionally augmented carbohydrate utilization locus from herbivore gut microbiota fueled by dietary β-glucans
    F Mandelli, MP Martins, M Chinaglia, EA Lima, MAB Morais, TB Lima, ...
    npj Biofilms and Microbiomes 10 (1), 105 , 2024
    2024
    Citations: 8
  • Glycosidase mechanisms: Sugar conformations and reactivity in endo-and exo-acting enzymes
    MAB Morais, A Nin-Hill, C Rovira
    Current Opinion in Chemical Biology 74, 102282 , 2023
    2023
    Citations: 31
  • Molecular plasticity of CBM3 ancillary domain leads to conformational changes in the cellulose binding interface
    MAB Morais, JH Paiva, MT Murakami
    Biochemical and Biophysical Research Communications 645, 71-78 , 2023
    2023
    Citations: 2
  • Mechanism of high-mannose N -glycan breakdown and metabolism by Bifidobacterium longum
    RL Cordeiro, CR Santos, MN Domingues, TB Lima, RAS Pirolla, ...
    Nature Chemical Biology 19 (2), 218-229 , 2023
    2023
    Citations: 27
  • State-of-the-art experimental and computational approaches to investigate structure, substrate recognition, and catalytic mechanism of enzymes
    CR Santos, CA dos Santos, EA de Araujo, MAB Morais, ...
    Polysaccharide Degrading Biocatalysts, 75-107 , 2023
    2023
  • Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans
    MP Martins, MAB Morais, GF Persinoti, RH Galinari, L Yu, Y Yoshimi, ...
    Acta Crystallographica Section D: Structural Biology 78 (11) , 2022
    2022
    Citations: 8
  • Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides
    L Cabral, GF Persinoti, DAA Paixão, MP Martins, MAB Morais, ...
    Nature Communications 13 (1), 629 , 2022
    2022
    Citations: 104
  • Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides. Nat Commun 13: 629
    L Cabral, GF Persinoti, DAA Paixão, MP Martins, MAB Morais, ...
    2022
    Citations: 9
  • Xyloglucan processing machinery in Xanthomonas pathogens and its role in the transcriptional activation of virulence factors
    PS Vieira, IM Bonfim, EA Araujo, RR Melo, AR Lima, MR Fessel, ...
    Nature Communications 12 (1), 4049 , 2021
    2021
    Citations: 88
  • Gut microbiome of capybara, the Amazon master of the grasses, harbors unprecedented enzymatic strategies for plant glycans breakdown
    L Cabral, GF Persinoti, DAA Paixao, MP Martins, M Chinaglia, ...
    2021
    Citations: 4
  • Two distinct catalytic pathways for GH43 xylanolytic enzymes unveiled by X-ray and QM/MM simulations
    MAB Morais, J Coines, MN Domingues, RAS Pirolla, CCC Tonoli, ...
    Nature Communications 12 (1), 1-13 , 2021
    2021
    Citations: 52
  • A single P115Q mutation modulates specificity in the Corynebacterium pseudotuberculosis arginine repressor
    RB Mariutti, JE Hernandez-Gonzalez, AFZ Nascimento, MAB de Morais, ...
    Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (7), 129597 , 2020
    2020
    Citations: 1

MOST CITED SCHOLAR PUBLICATIONS

  • Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides
    L Cabral, GF Persinoti, DAA Paixão, MP Martins, MAB Morais, ...
    Nature Communications 13 (1), 629 , 2022
    2022
    Citations: 104
  • An engineered GH1 β-glucosidase displays enhanced glucose tolerance and increased sugar release from lignocellulosic materials
    CA Santos, MAB Morais, OM Terrett, JJ Lyczakowski, LM Zanphorlin, ...
    Scientific Reports 9 , 2019
    2019
    Citations: 95
  • Xyloglucan processing machinery in Xanthomonas pathogens and its role in the transcriptional activation of virulence factors
    PS Vieira, IM Bonfim, EA Araujo, RR Melo, AR Lima, MR Fessel, ...
    Nature Communications 12 (1), 4049 , 2021
    2021
    Citations: 88
  • How pH Modulates the Dimer-Decamer Interconversion of 2-Cys Peroxiredoxins from the Prx1 Subfamily
    MA Morais, PO Giuseppe, TA Souza, TG Alegria, MA Oliveira, LE Netto, ...
    Journal of Biological Chemistry 2090, 8582-8590 , 2015
    2015
    Citations: 70
  • A metagenomic ‘dark matter’enzyme catalyses oxidative cellulose conversion
    CA Santos, MAB Morais, F Mandelli, EA Lima, RY Miyamoto, PMR Higasi, ...
    Nature 639 (8056), 1076-1083 , 2025
    2025
    Citations: 53
  • Two distinct catalytic pathways for GH43 xylanolytic enzymes unveiled by X-ray and QM/MM simulations
    MAB Morais, J Coines, MN Domingues, RAS Pirolla, CCC Tonoli, ...
    Nature Communications 12 (1), 1-13 , 2021
    2021
    Citations: 52
  • The mechanism by which a distinguishing arabinofuranosidase can cope with internal di-substitutions in arabinoxylans
    CR Dos Santos, PO de Giuseppe, FHM de Souza, LM Zanphorlin, ...
    Biotechnology for Biofuels 11 (1), 223 , 2018
    2018
    Citations: 39
  • Glycosidase mechanisms: Sugar conformations and reactivity in endo-and exo-acting enzymes
    MAB Morais, A Nin-Hill, C Rovira
    Current Opinion in Chemical Biology 74, 102282 , 2023
    2023
    Citations: 31
  • Structural basis of exo-β-mannanase activity in the GH2 family
    MN Domingues, FHM Souza, PS Vieira, MAB de Morais, LM Zanphorlin, ...
    Journal of Biological Chemistry 293 (35), 13636-13649 , 2018
    2018
    Citations: 30
  • Mechanism of high-mannose N -glycan breakdown and metabolism by Bifidobacterium longum
    RL Cordeiro, CR Santos, MN Domingues, TB Lima, RAS Pirolla, ...
    Nature Chemical Biology 19 (2), 218-229 , 2023
    2023
    Citations: 27
  • Structure‐guided design combined with evolutionary diversity led to the discovery of the xylose‐releasing exo‐xylanase activity in the glycoside hydrolase family 43
    LM Zanphorlin, MAB de Morais, JA Diogo, MN Domingues, ...
    Biotechnology and bioengineering 116 (4), 734-744 , 2019
    2019
    Citations: 24
  • A novel β-glucosidase isolated from the microbial metagenome of Lake Poraquê (Amazon, Brazil)
    D Toyama, MAB de Morais, FC Ramos, LM Zanphorlin, CCC Tonoli, ...
    Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (4), 569-579 , 2018
    2018
    Citations: 20
  • Exploring the Molecular Basis for Substrate Affinity and Structural Stability in Bacterial GH39 β-Xylosidases
    MAB Morais, CC Polo, MN Domingues, GF Persinoti, RAS Pirolla, ...
    Frontiers in Bioengineering and Biotechnology 8, 419 , 2020
    2020
    Citations: 19
  • How high pressure pre-treatments affect the function and structure of hen egg-white lysozyme
    AAL Tribst, MAB de Morais, CY Tominaga, AFZ Nascimento, ...
    Innovative Food Science & Emerging Technologies 47, 195-203 , 2018
    2018
    Citations: 19
  • Spatially remote motifs cooperatively affect substrate preference of a ruminal GH26-type endo-β-1, 4-mannanase
    F Mandelli, MAB de Morais, EA de Lima, L Oliveira, GF Persinoti, ...
    Journal of Biological Chemistry 295 (15), 5012-5021 , 2020
    2020
    Citations: 18
  • Calcium and magnesium ions modulate the oligomeric state and function of mitochondrial 2-Cys peroxiredoxins in Leishmania parasites
    MA Morais, PO Giuseppe, TA Souza, H Castro, RV Honorato, ...
    Journal of Biological Chemistry 292, 7023–7039 , 2017
    2017
    Citations: 15
  • Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides. Nat Commun 13: 629
    L Cabral, GF Persinoti, DAA Paixão, MP Martins, MAB Morais, ...
    2022
    Citations: 9
  • Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the mitochondrial tryparedoxin peroxidase from Leishmania braziliensis
    MAB de Morais, TACB de Souza, MT Murakami
    Acta Crystallographica Section F: Structural Biology and Crystallization … , 2013
    2013
    Citations: 9
  • A functionally augmented carbohydrate utilization locus from herbivore gut microbiota fueled by dietary β-glucans
    F Mandelli, MP Martins, M Chinaglia, EA Lima, MAB Morais, TB Lima, ...
    npj Biofilms and Microbiomes 10 (1), 105 , 2024
    2024
    Citations: 8
  • Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans
    MP Martins, MAB Morais, GF Persinoti, RH Galinari, L Yu, Y Yoshimi, ...
    Acta Crystallographica Section D: Structural Biology 78 (11) , 2022
    2022
    Citations: 8