McCaide Thomas Wooten

@ucalgary.ca

PhD Candidate, Faculty of Veterinary Medicine
University of Calgary

https://researchid.co/mcwooten

EDUCATION

Master of Preventive Veterinary Medicine, University of California - Davis, 2022
Doctor of Veterinary Medicine, North Carolina State University, 2019
Bachelor of Science - Poultry Science, North Carolina State University, 2015
Bachelor of Science - Animal Science, North Carolina State University, 2015

RESEARCH, TEACHING, or OTHER INTERESTS

Veterinary, Epidemiology, Animal Science and Zoology, Infectious Diseases

Scopus Publications

Scholar Citations

Scholar h-index

Scopus Publications

A RETROSPECTIVE EVALUATION OF MORBIDITY AND MORTALITY IN ASSOCIATION WITH INFESTATION BY THE MITE STERNOSTOMA TRACHEACOLUM IN AN AVIARY-HOUSED POPULATION OF GOULDIAN FINCHES (CHLOEBIA GOULDIAE)
McCaide T. Wooten, Carmel Witte, Meg Sutherland-Smith, Patricia M. Gaffney, and Kathryn C. Conlon
American Association of Zoo Veterinarians
The Rhynonyssid mesostigmatic mite, Sternostoma tracheacolum, is a well-documented endoparasitic hematophagous arthropod of the respiratory tracts of multiple avian species, particularly Estrildid finches and canaries. In this retrospective study, 175 medical and 278 pathology records for the Gouldian finch (Chloebia gouldiae) population (N = 377) at the San Diego Zoo between 2013 and 2021 were analyzed to evaluate the effectiveness of ivermectin-based prophylaxis. A multivariable negative binomial regression model was constructed to evaluate the population effects of monthly treatments on morbidity or mortality associated with respiratory mites. While controlling for other factors in the model, the prophylactic treatment did not significantly reduce the monthly rate of mite-associated morbidity or mortality (IRR = 1.017, 95% CI: 0.997-1.036, P = 0.0759); however, low proportions of the population were prophylactically treated over time. Different factors were significant when separately evaluating adjusted associations with respiratory morbidity and mortality. The findings suggest increased rates of respiratory morbidity for each successive year of the study period (IRR = 1.180, 95% CI: 1.046-1.342, P = 0.0090) and increased rates of mite-associated mortality occurring annually between May and October (IRR = 1.697, 95% CI: 1.034-2.855, P = 0.0404) compared to the wet winter season. Our findings highlight the need to continually evaluate and optimize treatment regimens in zoological collections. Further investigations into this host-parasite relationship and potential treatments and preventive therapies are warranted.

Red blood cell distribution width to platelet ratio in neonatal foals with sepsis
Rebeca Scalco, Gabriela Novo de Oliveira, Bruna da Rosa Curcio, McCaide Wooten, K. Gary Magdesian, Stephanie Takako Hidai, Pranav Pandit, and Monica Aleman
Wiley
AbstractBackgroundRapid and accurate markers to aid diagnosis of sepsis are needed in neonatal foals. The CBC variable red blood cell distribution width (RDW) to platelet ratio (RPR) is associated with inflammatory response and linked to poor outcomes of sepsis in human patients.HypothesisExplore the correlation of RPR with sepsis in neonatal foals and evaluate RPR predictive and prognostic value.AnimalsThree hundred seventeen hospitalized neonatal foals ≤7 days of age that had a CBC and physical exam performed at admission between 2012 and 2021.MethodsRetrospective case‐control study. Clinical records were used to calculate sepsis scores and define groups. Red blood cell distribution width to platelet ratio was calculated and compared between groups (septic vs nonseptic) based on Kruskal‐Wallis and Wilcoxon signed‐rank tests. A multivariate logistic regression model to predict sepsis was created. The cutoff for RPR was obtained based on the maximal Youden Index. The Kaplan‐Meier method and the log‐rank test were used to estimate survival curves and compare survival rates based on RPR.ResultsRed blood cell distribution width to platelet ratio was significantly higher in septic foals (Median = 0.099, confidence interval [CI] [0.093; 0.108]) than in sick nonseptic (0.085, CI [0.083; 0.089]) and healthy foals (0.081, CI [0.077; 0.086]; P < .0001). Red blood cell distribution width to platelet ratio was able to predict sepsis with high accuracy (AUC = 82.1%). The optimal RPR cutoff for sepsis was 0.09.Conclusions and Clinical ImportanceRed blood cell distribution width to platelet ratio calculation is practical, inexpensive, and based on CBC‐derived data. Calculation of RPR along with CBC can aid in the diagnosis of sepsis and estimation of outcome.

In sea turtles presenting for cold-stunning (sustained hypothermia), what blood analytes routinely evaluated at intake provide the most prognostic value?
McCaide Wooten
RCVS Knowledge
Question In sea turtles presenting for cold-stunning (sustained hypothermia), what blood analytes routinely evaluated at intake provide the most prognostic value? Clinical bottom line Category of research question Prognosis. The number and type of study designs reviewed Ten studies were included in this evaluation including the following study designs: eight retrospective case series, one cross-sectional, and one retrospective cohort. Strength of evidence Weak. Outcomes reported The most consistent finding across all included studies in cold-stunned sea turtles was acidosis (suspected both respiratory or metabolic components) characterised by reduced blood pH, elevated partial pressure of carbon dioxide (pCO2), and reduced partial pressure of oxygen (pO2). However, this finding was not necessarily linked with failure of rehabilitation. Rather, sea turtles presenting for cold-stunning that did not survive rehabilitative therapy were typically in extreme states of homeostatic derangement involving acidosis, but often in conjunction with additional abnormalities (e.g. anaemia, sepsis, organ failure or dysfunction, pneumonia, etc.). Conclusion As might be expected, the evaluated literature did not reveal a single or series of blood analytes that were definitively linked with the success or failure of rehabilitation in sea turtles presenting for cold-stunning. However, they did identify analytes that may provide the most clinical value in this clinical situation including packed cell volume (PCV), estimated white blood cell count (WBC), total and / or ionised calcium, pH, potassium (K), and lactate. Review of the available studies on the topic provides insightful information that can aid clinicians addressing this syndrome to triage and treat affected individuals most effectively. It also elucidated areas of opportunity for further research. How to apply this evidence in practice The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources. Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.

Gastrointestinal obstruction secondary to seminal vesicle cystic hyperplasia in an African pygmy hedgehog (Atelerix albiventris)
McCaide T. Wooten and Timothy A. Snider
Wiley
AbstractA 3‐year‐old, male, entire African pygmy hedgehog (Atelerix albiventris) was presented for a 10‐day history of hyporexia, mucoid green faeces and lethargy. Survey radiographs revealed a left caudal abdominal mass effect with cranial displacement and gas distension of the intestinal loops. During exploratory laparotomy, the cause of the mass effect was revealed to be grossly enlarged seminal vesicles, which were excised. Histopathology revealed uniform polycystic glandular architecture, consistent with benign cystic hyperplasia. The patient recovered and was clinically healthy at the last follow‐up examination. This is the first detailed report describing the antemortem diagnosis of benign seminal vesicular cystic hyperplasia resulting in presumptive clinical gastrointestinal disease in an African pygmy hedgehog.

Effect of Nutritional Variance of Energy and Crude Protein on Sex Ratio and Development of W-36 Parent Offspring

Protein and caloric intake on the reproductive performance parameters of Hyline W-36 parent stock males
Zachary S. Lowman, McCaide T. Wooten, Christopher M. Ashwell, Kenneth E. Anderso, and H. John Barne
Science Alert

Impact of egg shape on hatchability in pekin ducks
Zachary S. Lowman, Carmen R. Parkhurst, and McCaide T. Wooten
Science Alert

RECENT SCHOLAR PUBLICATIONS

Parasitic larval nematode meningoencephalitis in a blue shark (Prionace glauca) causing abnormal behavior
MC Wooten, B DePoister, J Humphrey, R Jones
The Aquatic Veterinarian 18 (1), 22-24 2024

Red blood cell distribution width to platelet ratio in neonatal foals with sepsis
R Scalco, GN de Oliveira, B da Rosa Curcio, MC Wooten, KG Magdesian, ...
Journal of veterinary internal medicine 37 (4), 1552-1560 2023

In sea turtles presenting for cold-stunning (sustained hypothermia), what blood analytes routinely evaluated at intake provide the most prognostic value?
MC Wooten
Veterinary Evidence 8 (1) 2023

Gastrointestinal obstruction secondary to seminal vesicle cystic hyperplasia in an African pygmy hedgehog (Atelerix albiventris)
MCT Wooten, TA Snider
Veterinary Record Case Reports, e446 2022

Effect of Nutritional Variance of Energy and Crude Protein on Sex Ratio and Development of W-36 Parent Offspring
MCT Wooten, ZS Lowman, CM Ashwell
Poultry Science Journal 9 (2), 255-262 2021

Protein and Caloric Intake on the Reproductive Performance Parameters of Hy-Line W-36 Parent Stock Males
ZS Lowman, MCT Wooten, CM Ashwell, KE Anderson
International Journal of Poultry Science 16 (7), 242-247 2017

Impact of egg shape on hatchability in Pekin ducks
ZS Lowman, CR Parkhurst, MT Wooten
International Journal of Poultry Science 15 (5), 188-191 2016

MOST CITED SCHOLAR PUBLICATIONS

Gastrointestinal obstruction secondary to seminal vesicle cystic hyperplasia in an African pygmy hedgehog (Atelerix albiventris)
MCT Wooten, TA Snider
Veterinary Record Case Reports, e446 2022
Citations: 1

Impact of egg shape on hatchability in Pekin ducks
ZS Lowman, CR Parkhurst, MT Wooten
International Journal of Poultry Science 15 (5), 188-191 2016
Citations: 1