MEENA KRISHNAKAR CHINTAMANENI
@nmims.edu
Scopus Publications
- Phytochemical interventions of medicinal plants in the management of diabetes and obesity: A recent therapeutic overview
D’Souza Keith, Ketaki Apte, Ansh Chintamaneni, Ansh Chintamaneni, Meena Chintamaneni, Ujjawal Sharma, Bunty Sharma, Moyad Shahwan, Ginpreet Kaur, Damandeep Kaur, Hardeep Singh Tuli
Journal of Applied Pharmaceutical Science, 2026
Over the past four decades, the global surge in diabetes and obesity has given rise to the term “diabesity,” reflecting the strong connection between type 2 diabetes and obesity. This link is correlated with heightened risks of cardiovascular disease, hypertension, and stroke. In light of this escalating health crisis, medicinal plants and natural products, which have long been used in traditional medicine systems, have attracted growing interest for their potential to address diabetes and obesity. This review highlights scientific evidence from preclinical and clinical studies on the efficacy of medicinal plants in treating diabetes and obesity. It focuses on the phytoconstituent responsible for these benefits and supports their traditional therapeutic use while comparing with common therapeutic interventions. Additionally, the review delves into the mechanism of action through which these plants demonstrate their benefits and explores modern formulations that fuse traditional knowledge with current healthcare practices. As diabesity continues to rise globally, understanding the role of medicinal plants in managing this dual condition offers valuable insights into alternative and complementary approaches for comprehensive healthcare. - Combination of the First-in-Class Imipridone ONC201 and Standard Anticancer Therapies as a Rational Approach for Therapeutic Benefit
Brahmi Shenoy, Miloni Mandani, Meena Chintamaneni, Sonal M. Manohar
Current Issues in Molecular Biology, 2025
The development of drugs for cancer treatment faces critical challenges due to the heterogeneity in cancers, metastatic nature of the disease, lack of efficacy, toxicity, and drug resistance. This makes it quite important to understand the complexities of cancer as well as the limitations of druggable targets. ONC201 (also known as dordaviprone/TIC10/ModeysoTM), a first-in-class member of the imipridone family, has been shown to kill cancer cells selectively. Recently, it has received FDA approval as the first and only treatment for recurrent H3K27M-mutant diffuse midline glioma. The unique pharmacophore, favorable therapeutic index, ability to induce TRAIL and the integrated stress response (ISR), activation of natural killer cells, and ability to diffuse across the blood–brain barrier are the unique characteristics of ONC201. ONC201 has shown effectiveness against various cancers, and this has been evident in many preclinical studies. ONC201 as a single agent, although useful, has some limitations, which could be addressed by using combination strategies. ONC201 has shown synergism with other drugs, leading to greater tumor cell death or reduced tumor growth. Next-generation imipridones, viz. ONC206 and ONC212, are more potent analogs of ONC201 and exhibit similar characteristics. In this review, we discuss the therapeutic potential of ONC201 and its analogs using combination strategies across different cancers. - Liquid biopsy in pancreatic cancer: technologies and diagnostic biomarkers
Siddhi Awate, Dhanvi Sheth, Meena Chintamaneni, Ginpreet Kaur
Liquid Biopsy in Cancer Management Integrating Diagnostics and Clinical Applications, 2025 - Synergistic action of spices with chemotherapeutics
Anticancer Spices Dietary Input to Health, 2024 - Anti-inflammatory and antioxidant potential of spices, with a special focus on cancer management - Recent insights
Anticancer Spices Dietary Input to Health, 2024 - A current review on P2X7 receptor antagonist patents in the treatment of neuroinflammatory disorders: a patent review on antagonists
Simran Soni, Mihir S. Lukhey, Baban S. Thawkar, Meena Chintamaneni, Ginpreet Kaur, Hemant Joshi, Seema Ramniwas, Hardeep Singh Tuli
Naunyn Schmiedeberg S Archives of Pharmacology, 2024 - Mitigation of Dementia and Alzheimer’s Disease with Lipophilic Vitamins and Their Derivatives: Preclinical and Clinical Evidence
Dhruv Sanjay Gupta, Janvi Parekh, Daksh Sanjay Gupta, Harpal S. Buttar, Meena Chintamaneni, Ginpreet Kaur
Advances in Biochemistry in Health and Disease, 2024 - Evaluation of N 10-substituted acridone-based derivatives as AKT inhibitors against breast cancer cells: in vitro and molecular docking studies
Tanuja T. Yadav, Piyush D. Patil, Gulam Moin Shaikh, Maushmi S. Kumar, Meena Chintamaneni, Mayur YC
3 Biotech, 2023 - Targeted Therapies Used in the Treatment of Non–Small-Cell Lung Cancer: An Overview
Tanuja Yadav, Velisha Mehta, Nilam Bhusare, Meena Chintamaneni, Y. C. Mayur
Drug Repurposing for Emerging Infectious Diseases and Cancer, 2023 - Exploring the versatility of ciclopirox - from anti-fungal to anticancer agent and beyond
Dhishank Singh, , Ginpreet Kaur, Meena Chintamaneni, Hemant Joshi, Seema Ramniwas, Hardeep Singh Tuli, , , , , and
European Journal of Clinical and Experimental Medicine, 2023
Introduction and aim. Ciclopirox has been treating fungal infections for decades. Recent studies suggest ciclopirox may be repurposed to treat cancer, viral infections, and neurological disorders. Ciclopirox exerts anticancer by inhibiting multiple pathways of cancer cell growth and survival and anti-viral actions by reducing viral replication and altering the host immunological response to viral infection. Recent research suggests that ciclopirox may protect against neurodegenerative illnesses including Alzheimer’s and Parkinson’s. This narrative review shows ciclopirox’s potential to treat cancer, viral infections, and neurological diseases. Material and methods. Current relevant research publications focused on ciclopirox and its repurposing medicinal potential, therefore a well-designed technique was used to find them. „Ciclopirox”, „Anti-fungal”, „Anti-cancer”, „Repurposing”, and „Therapeutic potential” were used to search PubMed, Web of Science, EMBASE, and Google Scholar. Analysis of literature. Ciclopirox may reduce oxidative stress and inflammation, which may cause several illnesses. Overall, the repurposing of ciclopirox for the treatment of cancer, viral infections, and neurodegenerative disorders represents a promising avenue of research that warrants further investigation. Conclusion. It was concluded that CPX and olamine derivatives as outstanding antifungal medications, as well as provide information on ongoing research to use them for other illnesses. - Resveratrol and Its Role in the Management of B-Cell Malignancies—A Recent Update
Dhruv Sanjay Gupta, Vaishnavi Gadi, Ginpreet Kaur, Meena Chintamaneni, Hardeep Singh Tuli, Seema Ramniwas, Gautam Sethi
Biomedicines, 2023 - Correction to: Lefamulin: a New Hope in the Field of Community-Acquired Bacterial Pneumonia (Current Pharmacology Reports, (2022), 8, 6, (418-426), 10.1007/s40495-022-00297-6)
Shubham Adhikary, Meher Kaur Duggal, Saraswathy Nagendran, Meena Chintamaneni, Hardeep Singh Tuli, Ginpreet Kaur
Current Pharmacology Reports, 2022 - Lefamulin: a New Hope in the Field of Community-Acquired Bacterial Pneumonia
Shubham Adhikary, Meher Kaur Duggal, Saraswathy Nagendran, Meena Chintamaneni, Hardeep Singh Tuli, Ginpreet Kaur
Current Pharmacology Reports, 2022 - A Review on Fused Pyrimidine Systems as EGFR Inhibitors and Their Structure–Activity Relationship
Tanuja T. Yadav, Gulam Moin Shaikh, Maushmi S. Kumar, Meena Chintamaneni, Mayur YC
Frontiers in Chemistry, 2022 - Message
Mukesh Patel, Shri, Amrish Patel, Jennifer Gandhi, Jt Secretary, et al.
Ibssc 2022 IEEE Bombay Section Signature Conference, 2022 - Role of nutraceuticals, functional foods, and spices in the management of metabolic syndrome and related disorders
Avinash Shenoy, Harpal S. Buttar, ParnikaDilip Dicholkar, Ginpreet Kaur, Meena Chintamaneni
Functional Foods and Nutraceuticals in Metabolic and Non Communicable Diseases, 2021 - Therapeutic Interventions of Endocannabinoid Signaling in Obesity-Related Cardiovascular Dysfunction
Vivek S. Kumawat, Siddhi Bagwe-Parab, Meena Chintamaneni, Ginpreet Kaur
Advances in Biochemistry in Health and Disease, 2020 - A potential natural product combination targeting memory disorders
Vikas Kumar, A. Veeranjaneyulu
Herbs for Diabetes and Neurological Disease Management Research and Advancements, 2018 - Influence of piperine and quercetin on antidiabetic potential of curcumin
Ginpreet Kaur, Mihir Invally, Meena Chintamaneni
Journal of Complementary and Integrative Medicine, 2016 - A comparative study of the antibacterial activity of rosemary extract blended with polymeric biomaterials
SukhwinderK. Bhullar, Deepti Rana, Burcak Kaya Ozsel, Ramesh Yadav, Ginpreet Kaur, Meena Chintamaneni, HarpalS. Buttar, MartinB. G. Jun, Murugan Ramalingam
Journal of Bionanoscience, 2016 - Antibacterial activity of combination of synthetic and biopolymer non-woven structures
Sukhwinder K. Bhullar, Burcak Kaya Özsel, Ramesh Yadav, Ginpreet Kaur, Meena Chintamaneni, Harpal S. Buttar
Journal of Complementary and Integrative Medicine, 2015 - In vitro assessment of CYP1A2 and 2C9 inhibition potential of Withania somnifera and Centella asiatica in human liver microsomes
Jay Savai, Alice Varghese, Nancy Pandita, Meena Chintamaneni
Drug Metabolism and Personalized Therapy, 2015 - Investigation of CYP3A4 and CYP2D6 interactions of withania somnifera and centella asiatica in human liver microsomes
Jay Savai, Alice Varghese, Nancy Pandita, Meena Chintamaneni
Phytotherapy Research, 2015 - Investigation of cyp1a interaction potential of Withania somnifera in rat and human liver microsomes
International Journal of Pharmacy and Pharmaceutical Sciences, 2015 - Anti-inflammatory effects of Polygonum minus (Huds) extract (Lineminus™) in in-vitro enzyme assays and carrageenan induced paw edema
Annie George, Sasikala Chinnappan, Meena Chintamaneni, Vandana Kotak C, Yogendra Choudhary, Thomas Kueper, Ammu K Radhakrishnan
BMC Complementary and Alternative Medicine, 2014 - Lactose intolerance: Genetics of lactase polymorphisms, diagnosis and novel therapy
Erica Sequeira, Ginpreet Kaur, Meena Chintamaneni, Harpal S. Buttar
Biomedical Reviews, 2014 - A comparative, bioequivalence study to evaluate the safety and pharmacokinetic profile of single dose Ivabradine 7.5mg tablets in healthy, adult, human subjects under fasting condition
Research Journal of Pharmacy and Technology, 2012 - Pipeline and quercetin enhances antioxidant and hepatoprotective effect of curcumin in paracetamol induced oxidative stress
Astha Mehta, Ginpreet Kaur, Meena Chintamane
International Journal of Pharmacology, 2012 - Anti-infective potential of morinda citrifolia fruit extract
International Journal of Pharmacy and Pharmaceutical Sciences, 2011 - Simple, precise and accurate HPLC method of analysis for nevirapine suspension from human plasma
S. Halde, A. Mungantiwar, M. Chintamaneni
Indian Journal of Pharmaceutical Sciences, 2011 - New insights into molecular targets for urinary incontinence
Meena Chintamaneni, Ilesh Changela, ManojK Poonia, Ginpreet Kaur
Indian Journal of Pharmacology, 2010 - Determination of site of absorption of propranolol in rat gut using in situ single-pass intestinal perfusion
Anagha Damre, KS Singh, SR Mallurwar, Seethalakshmi Iyer, A Naik, Meena Chintamaneni, N Nagare
Indian Journal of Pharmaceutical Sciences, 2010 - Antioxidant potential of methanolic and hydrolyzed extracts of Eclipta alba
Pharmacologyonline, 2009
RECENT SCHOLAR PUBLICATIONS
- Asparagus racemosus Willd
P Bindal, R Kumar, G Kaur, M Chintamaneni
Medicinal and Aromatic Plants of India, Vol. 4, 75-89 , 2026
2026 - Liquid biopsy in pancreatic cancer: technologies and diagnostic biomarkers
S Awate, D Sheth, M Chintamaneni, G Kaur
Liquid biopsy in Cancer Management, 171-204 , 2026
2026 - Phytochemical interventions of medicinal plants in the management of diabetes and obesity: A recent therapeutic overview
DS Keith, K Apte, VS Kumawat, A Chintamaneni, M Chintamaneni, ...
Journal of Applied Pharmaceutical Science 16 (1), 046-069 , 2025
2025 - Combination of the First-in-Class Imipridone ONC201 and Standard Anticancer Therapies as a Rational Approach for Therapeutic Benefit
B Shenoy, M Mandani, M Chintamaneni, SM Manohar
Current Issues in Molecular Biology 47 (9), 775 , 2025
2025
Citations: 4 - Anti-Inflammatory and Antioxidant Potential of Spices, with a Special Focus on Cancer Management–Recent Insights
DS Gupta, RD Shingte, DS Gupta, M Chintamaneni, G Kaur, HS Tuli
Anticancer Spices, 185-224 , 2024
2024
Citations: 2 - Synergistic Action of Spices With Chemotherapeutics
SM Kothawade, S Maru, M Chintamaneni, HS Tuli, G Kaur
Anticancer Spices, 225-246 , 2024
2024
Citations: 1 - A current review on P2X7 receptor antagonist patents in the treatment of neuroinflammatory disorders: A patent review on antagonists
S Soni, MS Lukhey, BS Thawkar, M Chintamaneni, G Kaur, H Joshi, ...
Naunyn-Schmiedeberg's Archives of Pharmacology 397 (7), 4643-4656 , 2024
2024
Citations: 18 - Mitigation of Dementia and Alzheimer’s Disease with Lipophilic Vitamins and Their Derivatives: Preclinical and Clinical Evidence
DS Gupta, J Parekh, DS Gupta, HS Buttar, M Chintamaneni, G Kaur
Lipophilic Vitamins in Health and Disease, 85-105 , 2024
2024 - Exploring the versatility of ciclopirox–from anti-fungal to anticancer agent and beyond
D Singh, G Kaur, M Chintamaneni, H Joshi, S Ramniwas, HS Tuli
European Journal of Clinical and Experimental Medicine 21 (4), 896–908-896–908 , 2023
2023
Citations: 2 - Evaluation of N 10 -substituted acridone-based derivatives as AKT inhibitors against breast cancer cells: in vitro and molecular docking studies
TT Yadav, PD Patil, GM Shaikh, MS Kumar, M Chintamaneni, M Yc
3 Biotech 13 (4), 111 , 2023
2023
Citations: 2 - Targeted Therapies Used in the Treatment of Non–Small-Cell Lung Cancer: An Overview
T Yadav, V Mehta, N Bhusare, M Chintamaneni, YC Mayur
Drug Repurposing for Emerging Infectious Diseases and Cancer, 111-158 , 2023
2023 - Resveratrol and its role in the management of B-cell malignancies—A recent update
DS Gupta, V Gadi, G Kaur, M Chintamaneni, HS Tuli, S Ramniwas, ...
Biomedicines 11 (1), 221 , 2023
2023
Citations: 13 - Correction to: Lefamulin: a New Hope in the Field of Community-Acquired Bacterial Pneumonia
S Adhikary, MK Duggal, S Nagendran, M Chintamaneni, HS Tuli, G Kaur
Current Pharmacology Reports 8 (6), 464-466 , 2022
2022 - Lefamulin: a new hope in the field of community-acquired bacterial pneumonia
S Adhikary, MK Duggal, S Nagendran, M Chintamaneni, HS Tuli, G Kaur
Current Pharmacology Reports 8 (6), 418-426 , 2022
2022
Citations: 22 - A review on fused pyrimidine systems as EGFR inhibitors and their structure–activity relationship
TT Yadav, G Moin Shaikh, MS Kumar, M Chintamaneni, M Yc
Frontiers in Chemistry 10, 861288 , 2022
2022
Citations: 43 - Recent Advances of Artificial Intelligence Tools in Attention-Deficit Hyperactivity Disorder (ADHD)
S Walvekar, B Thawkar, M Chintamaneni, G Kaur
Current Psychopharmacology 11 (1), 18-29 , 2022
2022
Citations: 2 - Role of nutraceuticals, functional foods, and spices in the management of metabolic syndrome and related disorders
A Shenoy, HS Buttar, PD Dicholkar, G Kaur, M Chintamaneni
Functional foods and nutraceuticals in metabolic and non-communicable … , 2022
2022
Citations: 30 - Therapeutic Potential of Phyto-Constituents for the Treatment of Alzheimer s Disease
P Thakkar, S Bagwe-Parab, G Kaur, M Chintamaneni, HS Buttar
Bentham Briefs in Biomedicine and Pharmacotherapy Oxidative Stress and … , 2021
2021 - Therapeutic roles of antioxidant and nutraceuticals in the prevention and management of Alzheimer’s disease: A systematic review
S Gupta, A Shenoy, V Chaudhari, HS Buttar, M Chintamaneni, G Kaur
Biomedical Reviews 32, 1-29 , 2021
2021 - Therapeutic Interventions of Endocannabinoid Signaling in Obesity-Related Cardiovascular Dysfunction
VS Kumawat, S Bagwe-Parab, M Chintamaneni, G Kaur
Biochemistry of Cardiovascular Dysfunction in Obesity, 267-281 , 2020
2020
MOST CITED SCHOLAR PUBLICATIONS
- Anti-inflammatory effects of Polygonum minus (Huds) extract (Lineminus™) in in-vitro enzyme assays and carrageenan induced paw edema
A George, S Chinnappan, M Chintamaneni, V Kotak C, Y Choudhary, ...
BMC complementary and alternative medicine 14 (1), 355 , 2014
2014
Citations: 90 - Biomarkers in Alzheimer′ s Disease: A Review
M Chintamaneni, M Bhaskar
International Scholarly Research Notices 2012 (1), 984786 , 2012
2012
Citations: 85 - Investigation of CYP3A4 and CYP2D6 Interactions of Withania somnifera and Centella asiatica in Human Liver Microsomes
J Savai, A Varghese, N Pandita, M Chintamaneni
Phytotherapy Research 29 (5), 785-790 , 2015
2015
Citations: 57 - Influence of piperine and quercetin on antidiabetic potential of curcumin
G Kaur, M Invally, M Chintamaneni
Journal of Complementary and Integrative Medicine 13 (3), 247-255 , 2016
2016
Citations: 47 - A review on fused pyrimidine systems as EGFR inhibitors and their structure–activity relationship
TT Yadav, G Moin Shaikh, MS Kumar, M Chintamaneni, M Yc
Frontiers in Chemistry 10, 861288 , 2022
2022
Citations: 43 - Determination of site of absorption of propranolol in rat gut using in situ single-pass intestinal perfusion
N Nagare, A Damre, KS Singh, SR Mallurwar, S Iyer, A Naik, ...
Indian journal of pharmaceutical sciences 72 (5), 625 , 2010
2010
Citations: 42 - Piperine and quercetin enhances antioxidant and hepatoprotective effect of curcumin in paracetamol induced oxidative stress
A Mehta, G Kaur, M Chintamaneni
International Journal of pharmacology 8 (2), 101-107 , 2012
2012
Citations: 39 - Role of nutraceuticals, functional foods, and spices in the management of metabolic syndrome and related disorders
A Shenoy, HS Buttar, PD Dicholkar, G Kaur, M Chintamaneni
Functional foods and nutraceuticals in metabolic and non-communicable … , 2022
2022
Citations: 30 - In vitro assessment of CYP1A2 and 2C9 inhibition potential of Withania somnifera and Centella asiatica in human liver microsomes
J Savai, A Varghese, N Pandita, M Chintamaneni
Drug metabolism and personalized therapy 30 (2), 137-141 , 2015
2015
Citations: 25 - Lefamulin: a new hope in the field of community-acquired bacterial pneumonia
S Adhikary, MK Duggal, S Nagendran, M Chintamaneni, HS Tuli, G Kaur
Current Pharmacology Reports 8 (6), 418-426 , 2022
2022
Citations: 22 - A current review on P2X7 receptor antagonist patents in the treatment of neuroinflammatory disorders: A patent review on antagonists
S Soni, MS Lukhey, BS Thawkar, M Chintamaneni, G Kaur, H Joshi, ...
Naunyn-Schmiedeberg's Archives of Pharmacology 397 (7), 4643-4656 , 2024
2024
Citations: 18 - Resveratrol and its role in the management of B-cell malignancies—A recent update
DS Gupta, V Gadi, G Kaur, M Chintamaneni, HS Tuli, S Ramniwas, ...
Biomedicines 11 (1), 221 , 2023
2023
Citations: 13 - Lactose intolerance: genetics of lactase polymorphisms, diagnosis and novel therapy
E Sequeira, G Kaur, M Chintamaneni, HS Buttar
Biomedical Reviews 25, 35-44 , 2014
2014
Citations: 13 - Simple, precise and accurate HPLC method of analysis for nevirapine suspension from human plasma
S Halde, A Mungantiwar, M Chintamaneni
Indian Journal of Pharmaceutical Sciences 73 (4), 416 , 2011
2011
Citations: 13 - Investigation of CYP1A interaction potential of Withania somnifera in rat and human liver microsomes
J Savai, N Pandita, M Chintamaneni
Indian J. Pharm. Sci 76, 138-147 , 2014
2014
Citations: 12 - Investigating the role of Eclipta alba on brain antioxidant markers, cognitive performance and acetylcholinesterase activity of rats
M Bhaskar, M Chintamaneni
Int J Pharmace Phytopharmaco Res 3, 390-394 , 2014
2014
Citations: 9 - New insights into molecular targets for urinary incontinence
MK Poonia, G Kaur, M Chintamaneni, I Changela
Indian Journal of Pharmacology 42 (5), 261-266 , 2010
2010
Citations: 9 - Antibacterial activity of combination of synthetic and biopolymer non-woven structures
SK Bhullar, BK Özsel, R Yadav, G Kaur, M Chintamaneni, HS Buttar
Journal of Complementary and Integrative Medicine 12 (4), 289-294 , 2015
2015
Citations: 8 - Antioxidant potential of methanolic and hydrolyzed extracts of Eclipta alba
G Kaur, R Tuli, M Chintamaneni
Pharmacologyonline 2, 947-56 , 2009
2009
Citations: 8 - A comparative, Bioequivalence study to evaluate the safety and pharmacokinetic profile of single dose Ivabradine 7.5 mg Tablets in healthy, adult, human subjects under fasting …
AK Choulwar, AA Mungantiwar, M Chintamaneni
Research Journal of Pharmacy and Technology 5 (5), 658 , 2012
2012
Citations: 5
