Mini Raman

@ngmc.org

Assistant Professor, Post Graduate Department of Chemistry
Nallamuthu Gounder Mahalingam College

Mini Raman


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https://researchid.co/miniraman

RESEARCH INTERESTS

Phytochemistry, Organic Chemistry
5

Scopus Publications

58

Scholar Citations

5

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • GREEN SYNTHESIS OF SILVER NANOPARTICLES FROM Scoparia dulcis L. PLANT EXTRACT AND ITS In-vitro ACETYLCHOLINESTERASE, ANTIOXIDANT ACTIVITY
    R. Mini, V. Prabhu, K. Poonkodi, K. Vimaladevi, K. Revathi
    Rasayan Journal of Chemistry, 2023
    Silver oxide nanoparticles exhibit distinctive material and biotic properties that contain passionate research impact as vital applications in the pharmaceutical, biomedical, paper and textile industries. The goal of the current task is to synthesize AgNPs through a facile, low-cost, environmentally friendly route. In this method, we use the aqueous leaf extract of Scoparia dulcis Linn, found in the Western Ghats region, because the use of an aqueous medium is critical for reducing time and minimizing the possibility of side effects. The synthesized Ag nanoparticles were evaluated using UV-Visible, FTIR technique, scanning electron microscopy (SEM) with EADX, transmission electron microscopy (TEM), X-ray powder diffraction (XRD). Results confirmed that UV-visible spectroscopic analysis showed the absorbance peak at 460 nm, which implies the formation of silver nanoparticles. The FTIR spectrum aimed to such that biomolecules involved in wrapping and binding AgNPs synthesized by the plant extract. SEM and TEM are used to visualize the size and shape of nanoparticles. The XRD analysis revealed spherical structures with an average grain size of 21nm and a diameter range of 2 to 20nm. The EDAX study also exhibits the presence of 86.34 % Silver and 13.6 % Oxygen. Alzheimer's disease symptoms were controlled with a drug known as an acetylcholinesterase inhibitor. The in vitro acetylcholinesterase inhibitory activity of the AgNPs from Scoparia dulcis plant extract was evaluated using an Ellman's test with an IC50 value of 149µg/ml. The generated nanoparticles significantly inhibit AChE. The SD-AgNPs were examined for antioxidant activity via the DPPH and ABTS assays having IC50 values of 73.29µg/ml and 55.29µg/ml, respectively
  • Bio synthesis, characterization of ZnO nanoparticles from Scoparia dulcis L. plant extract and its in-vitro antioxidant, acetylcholinesterase activity
    R Mini, V Prabhu, K Poonkodi, K Vimaladevi, M Anusuya, M Vasuki
    Plant Science Today, 2023
    The current investigation is focused on the use of green synthesis methods for zinc oxide nanoparticles (ZnO NPs) from Scoparia dulcis L. extract (SDE). SDE-mediated ZnO NPs (SDE-ZnO-NPs) were made using a simple and eco-friendly method that required little reaction time and calcinations temperature. UV-Vis, FTIR, X-ray powder diffraction, SEM, TEM & EDAX were used into characterizes the skeletal and synthetic properties concerning biosynthesized ZnO nonmaterial. The UV–Visible spectroscopy absorption peak for SDE-ZnO-NPs was found to be at 380 nm, confirming the production of ZnO NPs. The FTIR spectrum also revealed bioactive functional groups as well as metal-oxygen groups. Synthesized ZnO NPs had a rod shape in 200 nm, according to TEM examination. The Zn and O in the produced ZnO NPs were approved by the EDAX analysis. The XRD results revealed that it had a crystal structure that was similar to SDE-ZnO-NPs. The dose-related Acetylcholinesterase inhibitory action of SDE-ZnO NPs was determined utilizing the Ellman’s test. AChE activity of the synthesized nanoparticles showed potential inhibitory activity with IC50 values of 75.34 µg/mL. The antioxidant activity was investigated the biosynthesized ZnO-NPs using DPPH, ABTS assay.
  • GC-MS Analysis, Phytochemical Screening and Biological Activity of Bauhinia tomentosa (Linn.)
    R. Mini, V. Prabhu, K. Vimaladevi, J. Sowmiya, G. Sibi
    Asian Journal of Chemistry, 2021
    Present study aimed to evaluate the chemical composition and biological activity for methanolic extract of Bauhinia tomentosa (Linn.) leaves grown in Western Ghats region of South India. The preliminary phytochemical screening tests revealed the presence of steroids, alkaloids, terpenoids, flavonoids, glycosides and phenolic compounds in the leaf extract. A total of 19 compounds were identified through gas chromatography-mass spectroscopy (GC-MS) analysis of methanolic extract of B. tomentosa. The major compounds identified were phytol (23.96%), n-hexadecanoic acid (11.62%), squalene (8.85%) and the minor compounds are trans-bis(2-methylpropyl)-4,6-dioxane(0.13%), dihydro-cis-α-copaene-8-ol (0.14%), tetradecanoic acid (0.81%), respectively. Antibacterial activity of the extract showed the zone of inhibition 18 mm at 200 μg/mL against S. aureus, followed by 15 and 16 mm against S. anginosus, K. pneumoniae at 200 μg/mL, respectively. Antioxidant activity of methanolic extract of B. tomentosa leaves showed the maximum IC50 value with 75.07 % of scavenging activity at the concentration of 5 μg/mL.
  • Chemical Composition of Essential Oil of Cananga odorata (Lam.) Hook. F. & Thomson Leaves and Its Biological Activities
    Krishnasamy Vimaladevi, Madhiyan Selladurai, Kathirvel Poonkodi, Velliangiri Prabhu, Raman Mini, Balasubramaniyam Manojkumar
    Journal of Essential Oil Bearing Plants, 2021
    In the current study, the chemical constituents of leaf essential oil from Cananga odorata (Lam.) Hook. F. & Thomson were identified by GC/MS analysis. A total of 25 components (91.1 %) in the essential oil were identified. The major compounds present in the oil were trans-caryophyllene (19.7 %), ocimene (13.2 %), E, E-α-farnesene (10.3 %), phenylmethyl ester (5.6 %), farnesyl acetone (5.1 %), t-muurolol (4.2 %), farnesol (3.7 %), β-elemene (3.1 %), α-cadinol (3.0 %), copaene (2.9 %), benzyl benzoate (2.3 %), trans-farnesol (2.1 %). The essential oil is rich in sesquiterpenoids including sesquiterpenes hydrocarbon (42.3 %), monoterpene hydrocarbons (18.1 %), and in addition to that oxygenated compound representing (30.7 %). The Antioxidant efficiency of essential oil of C. odorata leaves was performed by DPPH radical method together with BHA as standard. The essential oil showed concentration-dependent antiradical activity with EC50 value of 19.5±1.25 μg/mL, when compared with standard BHA which showed EC50 value of 1.10±0.55 μg/mL. The in vitro anticancer potential of essential oil was evaluated by using MOLT-3 cell line by MTT assay. The C. odorata essential oil exhibited significant anticancer activity with IC50 value of 44.22 μg/mL. From the results, C. odorata essential oil has significant antioxidant and anticancer properties which can be utilised as a natural supplement as antioxidant and anticancer agents in pharmaceutical and food industries since it is available throughout the year.
  • Antidandruff activity of cassia auriculata and cassia alata through fatty acids mediated inhibition of malassezia furfur
    V. Prabhu, K. Poonkodi, K. Pradeep, S. Buvaneswari, R. Mini, K. Vimaladevi, M. Anusuya, Sibi G
    Journal of Applied and Natural Science, 2020
    Susceptibility of Malassezia furfur to certain medium chain fatty acids shed light onto novel strategies to control dandruff. This study explored antidandruff activity of the fatty acids and other bioactive compounds from flowers of Cassia auriculata and Cassia alata. The idea was supplementing the growth medium with fatty acids which are inhibitory to Malassezia so that plant-based antidandruff formulations could be developed based on the results. Chloroform and ethanolic flower extracts were tested there in vitro efficacy against M. furfur and the potential antidandruff compounds were identified by gas chromatography-mass spectrophotometry (GC-MS). Minimum inhibitory concentrations were determined for both the extracts and IC50 values of 50 and 88 µM for chloroform extract of C. auriculata and C. alata were recorded. For ethanol extract, IC50 values of 75 and 70 µM were exhibited by C. auriculata and C. alata, respectively. Inhibition of M. furfur through fatty acids from Cassia is the first report, and it is possible to include specific fatty acids in the growth media to inhibit the growth of Malassezia which could be later served as lead molecules in antidandruff formulations. Further, the presence of citronellol, pinitol, anthracenedione and chrysine in Cassia flower extracts and their antidandruff activity reported in this study needed further research on those compounds to formulate effective treatment of Malassezia associated diseases.

RECENT SCHOLAR PUBLICATIONS

  • Bio-Synthesis, Characterization of ZnO Nanoparticles from Scoparia dulcis L. Plant Extract and Its In Vitro Antioxidant, Acetylcholinesterase Activity
    R Mini, V Prabhu, K Poonkodi, K Vimaladevi, M Anusuya, M Vasuki
    Plant Sci. Today 10, 90-97 , 2023
    2023.0
    Citations: 5
  • green synthesis of silver nanoparticles from scoparia dulcis L. plant extract and its in-vitro acetylcholinesterase, antioxidant activity
    R Mini, V Prabhu, K Poonkodi, K Vimaladevi, K Revathi
    Rasayan J Chem [Internet] 16 (1), 214-222 , 2023
    2023.0
    Citations: 2
  • Chemical Composition of Essential Oil of Cananga odorata (Lam.) Hook. F. & Thomson Leaves and Its Biological Activities
    K Vimaladevi, M Selladurai, K Poonkodi, V Prabhu, R Mini, B Manojkumar
    Journal of Essential Oil Bearing Plants 24 (3), 596-602 , 2021
    2021.0
    Citations: 18
  • Antidandruff activity of Cassia auriculata and Cassia alata through fatty acids mediated inhibition of Malassezia furfur
    V Prabhu, K Poonkodi, K Pradeep, S Buvaneswari, R Mini, K Vimaladevi, ...
    Journal of Applied and Natural Science 12 (4), 532 , 2020
    2020.0
    Citations: 8
  • In vitro cytotoxicity potential of ethanol extract of Syzygium samarangense (Wt.)
    R Mini, K Vimaladevi, V Prabhu, M Anusuya, KS Saranya
    Kongunadu Research Journal 6 (1), 30-32 , 2019
    2019.0
    Citations: 4
  • PHYTOCHEMICAL ANALYSIS AND INVITRO ANTICANCER ACTIVITY OF ETHANOL EXTRACT OF WRIGHTIA TINCTORIA
    MR Vimaladevi. K
    "American International Journal of Research in Science, Technology … , 2019
    2019.0
  • Gc-Ms analysis of bioactive compounds present in the petroleum ether, chloroform and methanol extract of Ixora Coccinea’s flower and in-vitro cytotoxic activity of
    V Prabhu, KV Devi, MK Priya
    Int. J. Res. Anal. Rev 5, 801-807 , 2018
    2018.0
    Citations: 15
  • Chemical composition and in vitro antimicrobial, anti-MRSA activities of essential oil of Clerodendrum inerme (L.) Gaertn-grown in western Ghats Region
    K Poonkodi, K Vimaladevi, R Mini
    Int. J. Chemtech. Res. 10 (9), 277-282 , 2017
    2017.0
    Citations: 5
  • 1-Dichloroacetyl-t-3-isopropyl-r-2, c-6-diphenylpiperidin-4-one
    P Sugumar, R Kayalvizhi, R Mini, S Ponnuswamy, MN Ponnuswamy
    Structure Reports 69 (8), o1348-o1348 , 2013
    2013.0
  • 1-Dichloroacetyl-t-3, t-5-dimethyl-r-2, c-6-diphenylpiperidin-4-one
    P Sugumar, R Kayalvizhi, R Mini, S Ponnuswamy, MN Ponnuswamy
    Structure Reports 69 (4), o609-o609 , 2013
    2013.0
    Citations: 1
  • Adsorption of Crystal Violet Dye on Biomass from Bauhinia tomentosa Seed Pod Powder: Equilibrium and Kinetic Studies
    K Poonkodi
  • CHAPTER NAME PAGE NO
    MN Vijayalakshmi, P Archanaa, R Jayaprakash, MA Kalaivani, S Rekha, ...
  • S. No. Title Page No.
    V Ramya, V Sangeetha, K Vimaladevi, K Poonkodi, V Prabhu, R Mini, ...
  • Dr. S. Nathiya, Dr. D. Ananthi, Dr. S. Umarani, Dr. V. Karpagavalli
    P Anitha, MMS Priya, MT Ramya, V Thananjayan, A Dheivamani, ...
  • 21. A REVIEW ON COPPER FERRITE AND METAL DOPED COPPER FERRITE MATERIALS: SYNTHESIS AND ITS MAGNETIC PROPERTIES
    A NAGAVENI, M ANUSUYA, E JAYANTHI, B NARMADA, R MINI, ...
  • Ms. G. Nithya&Dr. N. Giri
    P GomathiDevi, R Vidwakalyani, B IndiraPriyadharshini, K Vimaladevi, ...

MOST CITED SCHOLAR PUBLICATIONS

  • Chemical Composition of Essential Oil of Cananga odorata (Lam.) Hook. F. & Thomson Leaves and Its Biological Activities
    K Vimaladevi, M Selladurai, K Poonkodi, V Prabhu, R Mini, B Manojkumar
    Journal of Essential Oil Bearing Plants 24 (3), 596-602 , 2021
    2021.0
    Citations: 18
  • Gc-Ms analysis of bioactive compounds present in the petroleum ether, chloroform and methanol extract of Ixora Coccinea’s flower and in-vitro cytotoxic activity of
    V Prabhu, KV Devi, MK Priya
    Int. J. Res. Anal. Rev 5, 801-807 , 2018
    2018.0
    Citations: 15
  • Antidandruff activity of Cassia auriculata and Cassia alata through fatty acids mediated inhibition of Malassezia furfur
    V Prabhu, K Poonkodi, K Pradeep, S Buvaneswari, R Mini, K Vimaladevi, ...
    Journal of Applied and Natural Science 12 (4), 532 , 2020
    2020.0
    Citations: 8
  • Bio-Synthesis, Characterization of ZnO Nanoparticles from Scoparia dulcis L. Plant Extract and Its In Vitro Antioxidant, Acetylcholinesterase Activity
    R Mini, V Prabhu, K Poonkodi, K Vimaladevi, M Anusuya, M Vasuki
    Plant Sci. Today 10, 90-97 , 2023
    2023.0
    Citations: 5
  • Chemical composition and in vitro antimicrobial, anti-MRSA activities of essential oil of Clerodendrum inerme (L.) Gaertn-grown in western Ghats Region
    K Poonkodi, K Vimaladevi, R Mini
    Int. J. Chemtech. Res. 10 (9), 277-282 , 2017
    2017.0
    Citations: 5
  • In vitro cytotoxicity potential of ethanol extract of Syzygium samarangense (Wt.)
    R Mini, K Vimaladevi, V Prabhu, M Anusuya, KS Saranya
    Kongunadu Research Journal 6 (1), 30-32 , 2019
    2019.0
    Citations: 4
  • green synthesis of silver nanoparticles from scoparia dulcis L. plant extract and its in-vitro acetylcholinesterase, antioxidant activity
    R Mini, V Prabhu, K Poonkodi, K Vimaladevi, K Revathi
    Rasayan J Chem [Internet] 16 (1), 214-222 , 2023
    2023.0
    Citations: 2
  • 1-Dichloroacetyl-t-3, t-5-dimethyl-r-2, c-6-diphenylpiperidin-4-one
    P Sugumar, R Kayalvizhi, R Mini, S Ponnuswamy, MN Ponnuswamy
    Structure Reports 69 (4), o609-o609 , 2013
    2013.0
    Citations: 1
  • PHYTOCHEMICAL ANALYSIS AND INVITRO ANTICANCER ACTIVITY OF ETHANOL EXTRACT OF WRIGHTIA TINCTORIA
    MR Vimaladevi. K
    "American International Journal of Research in Science, Technology … , 2019
    2019.0
  • 1-Dichloroacetyl-t-3-isopropyl-r-2, c-6-diphenylpiperidin-4-one
    P Sugumar, R Kayalvizhi, R Mini, S Ponnuswamy, MN Ponnuswamy
    Structure Reports 69 (8), o1348-o1348 , 2013
    2013.0
  • Adsorption of Crystal Violet Dye on Biomass from Bauhinia tomentosa Seed Pod Powder: Equilibrium and Kinetic Studies
    K Poonkodi
  • CHAPTER NAME PAGE NO
    MN Vijayalakshmi, P Archanaa, R Jayaprakash, MA Kalaivani, S Rekha, ...
  • S. No. Title Page No.
    V Ramya, V Sangeetha, K Vimaladevi, K Poonkodi, V Prabhu, R Mini, ...
  • Dr. S. Nathiya, Dr. D. Ananthi, Dr. S. Umarani, Dr. V. Karpagavalli
    P Anitha, MMS Priya, MT Ramya, V Thananjayan, A Dheivamani, ...
  • 21. A REVIEW ON COPPER FERRITE AND METAL DOPED COPPER FERRITE MATERIALS: SYNTHESIS AND ITS MAGNETIC PROPERTIES
    A NAGAVENI, M ANUSUYA, E JAYANTHI, B NARMADA, R MINI, ...
  • Ms. G. Nithya&Dr. N. Giri
    P GomathiDevi, R Vidwakalyani, B IndiraPriyadharshini, K Vimaladevi, ...