Milena Pencheva Miteva
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Chief assistant professor, PhD - Department of Technology, Materials and Materials Science, Faculty of Technical Sciences
University "Prof. Assen Zlatarov" Burgas
4
Scopus Publications
8
Scholar Citations
1
Scholar h-index
Scopus Publications
- Application of Ultrafiltration for Recovery of Bioactive Phenolic Compounds from Rose Wastewater
Mariya Dushkova, Marina Mitova, Ivan Bakardzhiyski, Milena Miteva-Petrova, and Nikolay Menkov
MDPI AG
The process of rose oil distillation generates a huge amount of waste byproducts, which often remain unused, and poses serious environmental challenges; at the same time, they contain polyphenols with antioxidant, antimicrobial, and therapeutic properties. The purpose of this work is to investigate the possible application of ultrafiltration using three polyacrylonitrile membranes (molecular weight cut-off 1 kDa, 10 kDa, and 25 kDa) to recover the total polyphenolic compounds, phenolic acids, and flavonoids from rose wastewater. The permeate flux, energy demand, contents of total polyphenolic compounds, phenolic acids, and flavonoid phenolic compounds were determined during ultrafiltration at a volume reduction ratio of 2, 4, 6 and 8, and the rejections and concentration factors were established. The optimal operation conditions for permeate flux, energy demand, rejection, concentration factor, and antioxidant activity were established at a volume reduction ratio of 8, transmembrane pressure of 0.5 MPa, and 1 kDa membrane. These working conditions will be used in our future investigations to obtain extrudates from rice semolina enriched with ultrafiltered rose wastewater. Protocatechuic and vanillic acid, determined by HPLC, increased in the retentate when the 1 kDa membrane was used, while gallic acid, catechin, p-coumaric acid, rutin, hesperidin, and rosmarinic acid decreased. - Possible toxicological properties of catechin from processed rose wastewater
Yana Koleva, Viktoria Trifonova, Milena Miteva, Elisaveta Todorova-Koynova, and Ana Dobreva
EDP Sciences
The positive effect of catechins has been proven with their antimicrobial, antiviral, anti-inflammatory and antioxidant actions for organisms, i.e. have important biological significance. More pharmacological functions have been discovered with catechins in-depth research. Catechins have various uses, such as controlling obesity, scavenging free radicals, delaying aging, inhibiting human pathogenic bacteria without harming the reproduction of beneficial bacteria, etc. The task of the work is to determine the properties (toxic) and environmental fate of catechin by means of in silico metods. - Skin sensitization evaluation of a flavanol from processed rose wastewater for cosmetic application
Yana Koleva, Milena Miteva, Viktoria Trifonova, Krasimira Stancheva, and Ana Dobreva
EDP Sciences
Flavanols are extremely relevant for application and study due to the beneficial effect they have for humans when used internally or externally. They are identified in almost all plant cultures, as their metabolic products. Their pronounced benefit for protecting and restoring the skin in case of mechanical damage, radiation, allergens, chemicals and infections has been proven. Due to their natural origin, their dermatological application is also preferred. In such a case, the action of the chemical compounds and the generated skin metabolites have different mechanisms of action with respect to DNA and binding to proteins. The preliminary assessment of skin sensitization is a complex and lengthy task. Depending on the results, it is necessary to have an efficient technological approach for the isolation of flavanols with skin sensitization. Evaluation of the probable skin metabolic activity of cosmetic products containing flavanol (Luteolin) from processed rose wastewater is the aim of the conducted research, as well as prediction of protein and DNA binding of its metabolites by in silico methods (OECD QSAR Toolbox). The parent structure of the compound, as well as some of its generated metabolites, exhibit reactivity, i.e. they have different mechanisms of action in terms of DNA and protein binding. - Flux Behaviour, Rejection and Concentration Factors, and Energy Demand during Ultrafiltration of Sweet Buttermilk
Mariya Dushkova, Mihaela Ivanova, Luca Trublet, Zhana Petkova, Olga Teneva, Milena Miteva-Petrova, Ivelina Desseva, and Dasha Mihaylova
MDPI AG
This work aimed to study the flux behavior, rejection and concentration factors, and energy demand to establish the optimal conditions during ultrafiltration of sweet buttermilk to produce ice cream. The experiments were conducted with a UF25-PAN membrane at a transmembrane pressure of 0.2, 0.35 and 0.5 MPa, and a volume reduction ratio (VRR) of 2, 3, 4, and 5. Total protein, fat, ash, and dry matter contents, phospholipid composition, and acidity of retentates and permeate were determined. The increase in the VRR led to a decrease in the permeate flux and an increase in the energy demand, rejection, and concentration factors of the main components of sweet buttermilk. The highest values of rejection and concentration factors established for fat were 98.65% and 4.93, respectively. The permeate flux and energy demand increased with the rise in the transmembrane pressure. The total phospholipids increased 2.8 times at VRR 5 compared to the initial buttermilk. The use of VRR 3 gave the best ratio between the permeate flux, the energy demand, and relatively high values of concentration and rejection factors. The use of VRR 5 will enrich the ice cream to the greatest extent to obtain a product with the highest level of biologically active substances (proteins, phospholipids, minerals). - Production of probiotic Bulgarian yoghurts obtained from an ultrafiltered cow's milk
S. Kodinova, M. Dushkova, M. Miteva-Petrova, V. Yanakieva, S. Petrov, and Z. Denkova
Compuscript, Ltd.
Ultrafiltration of skim cow’s milk with a UF10-PAN membrane at volume reduction ratios (VRRs) of 2 and 3 was performed. The ultrafiltration retentates obtained were used for production of probiotic yoghurts with three different starters. A control sample was prepared using skim cow’s milk. All yoghurts were analysed according to the following parameters: titratable acidity, dry matter, organoleptic characteristics, number of specific microorganisms (Lactobacillus bulgaricus and Streptococcus thermophilus) and the total count of viable lactic acid bacteria for 28 d of storage. The results showed that the increase in the VRR during ultrafiltration increased the titratable acidity, as well as the dry matter of all yoghurts. Ultrafiltration concentration led to an increase in the count of viable lactic acid bacteria in all yoghurts which improved their functional properties. The highest values of the total number of viable lactic acid bacteria were determined in yoghurts obtained with starter 1CM, followed by starters MZ2and ZD for both VRRs. Probiotic yoghurts with the highest organoleptic evaluation were obtained from ultrafiltration retentates at VRR = 2 and starters 1CM and MZ2. - Effect of hydrophobically modified PVA on the temperature-responsive structure and permeation of PAN-based composite ultrafiltration membranes
Milena Miteva, Darinka Christova, Sijka Ivanova, and Stoiko Petrov
Springer Science and Business Media LLC - Investigation of process characteristics during diafiltration of ultrafiltration whey retentate from kashkaval production
- Multifactorial modeling of the flux during ultrafiltration of strawberry extract
- Multi-factorial mathematical model for the flux during ultrafiltration of cow’s milk
RECENT SCHOLAR PUBLICATIONS
- Application of Ultrafiltration for Recovery of Bioactive Phenolic Compounds from Rose Wastewater
M Dushkova, M Mitova, I Bakardzhiyski, M Miteva-Petrova, N Menkov
Applied Sciences 15 (4), 2040 2025 - MEMBRANE TREATMENT OF WASTE WATER FROM THE HYDRODISTILLATION OF OIL-BEARING ROSES.
M MITEVA, A DOBREVA
AGROFOR International Journal 9 (3) 2024 - Possible toxicological properties of catechin from processed rose wastewater
Y Koleva, V Trifonova, M Miteva, E Todorova-Koynova, A Dobreva
BIO Web of Conferences 122, 01017 2024 - Skin sensitization evaluation of a flavanol from processed rose wastewater for cosmetic application
Y Koleva, M Miteva, V Trifonova, K Stancheva, A Dobreva
BIO Web of Conferences 122, 01016 2024 - Flux Behaviour, Rejection and Concentration Factors, and Energy Demand during Ultrafiltration of Sweet Buttermilk
M Dushkova, M Ivanova, L Trublet, Z Petkova, O Teneva, ...
Applied Sciences 13 (6), 3804 2023 - Production of probiotic Bulgarian yoghurts obtained from an ultrafiltered cow’s milk
S Kodinova, M Dushkova, M Miteva-Petrova, V Yanakieva, S Petrov, ...
Irish Journal of Agricultural and Food Research 59 (1), 1-11 2020 - Effect of hydrophobically modified PVA on the temperature-responsive structure and permeation of PAN-based composite ultrafiltration membranes
M Miteva, D Christova, S Ivanova, S Petrov
Polymer Bulletin 75, 2805-2817 2018 - VACUUM METALLIZATION OF POLYMER MEMBRANES OF DIFFERENT MORPHOLOGY WITH TITANIUM
M Miteva, V Slavova, S Petrov
ASSEN ZLATAROV UNIVERSITY BURGAS, BULGARIA 47, 37 2018 - INVESTIGATION OF PROCESS CHARACTERISTICS DURING DIAFILTRATION OF ULTRAFILTRATION WHEY RETENTATE FROM KASHKAVAL PRODUCTION
M DUSHKOVA, S KOZLUDZHOVA, K DINKOV, M MITEVA-PETROVA, ...
Bulgarian Journal of Agricultural Science 23 (2), 325-329 2017 - MULTIFACTORIAL MODELING OF THE FLUX DURING ULTRAFILTRATION OF STRAWBERRY EXTRACT
M DUSHKOVA, A DINCHEV, K MIHALEV, M MITEVA-PETROVA, ...
Bulgarian Journal of Agricultural Science 23 (1), 165-170 2017 - MULTI-FACTORIAL MATHEMATICAL MODEL FOR THE FLUX DURING ULTRAFILTRA-TION OF COW’S MILK
M Dushkova, S Kozludzhova, K Dinkov, M Miteva-Petrova, S Petrov
Bulgarian Journal of Agricultural Science 22 (3), 492-496 2016 - Preparation of flat asymmetric membranes from solutions of Pan and DMSO
MM Pencheva, PS Petrov, TD Dimitrova
Евразийский Союз Ученых, 147-150 2015 - Effect of ultrafiltration on the apple juice colour.
A Dinchev, M Dushkova, K Mihalev, M Miteva-Petrova, R Dinkova, ...
2015 - ИЗСЛЕДВАНЕ НА ОТНОСИТЕЛНАТА ПРОИЗВОДИТЕЛНОСТ ПРИ УЛТРАФИЛТРАЦИЯ НА МОДЕЛЕН РАЗТВОР НА ЯБЪЛКОВ ЕКСТРАКТ
М Душкова, А Динчев, К Михалев, М Митева-Петрова, Р Динкова, ...
2015 - Effect of solvent and thermal treatment on the structure of polyacrylonitrile membranes
MPM Stoiko Petrov Petrov
IJSR 3 (5), 2277-8179 2014 - Formation of membranes based on polyacrylonitrile and butadiene-acrylonitrile elastomer in the presence of copper ions
SP Petrov, MP Miteva
Chemical Papers 66 (11), 1039-1047 2012 - Running title: Ultrafiltration of whey from Kashkaval
S Kodinova, M Dushkova, M Miteva-Petrova, S Petrov, N Menkov, ...
- PREPARATION OF ULTRAFILTRATION MEMBRANES FROM MIXTURE OF POLYACRYLONITRILE AND BUTADIENE-NITRILE ELASTOMER
S Petrov, M Miteva
Природни науки, Технически науки, 51
MOST CITED SCHOLAR PUBLICATIONS
- Production of probiotic Bulgarian yoghurts obtained from an ultrafiltered cow’s milk
S Kodinova, M Dushkova, M Miteva-Petrova, V Yanakieva, S Petrov, ...
Irish Journal of Agricultural and Food Research 59 (1), 1-11 2020
Citations: 5 - Effect of solvent and thermal treatment on the structure of polyacrylonitrile membranes
MPM Stoiko Petrov Petrov
IJSR 3 (5), 2277-8179 2014
Citations: 5 - Formation of membranes based on polyacrylonitrile and butadiene-acrylonitrile elastomer in the presence of copper ions
SP Petrov, MP Miteva
Chemical Papers 66 (11), 1039-1047 2012
Citations: 5 - Effect of hydrophobically modified PVA on the temperature-responsive structure and permeation of PAN-based composite ultrafiltration membranes
M Miteva, D Christova, S Ivanova, S Petrov
Polymer Bulletin 75, 2805-2817 2018
Citations: 3 - Flux Behaviour, Rejection and Concentration Factors, and Energy Demand during Ultrafiltration of Sweet Buttermilk
M Dushkova, M Ivanova, L Trublet, Z Petkova, O Teneva, ...
Applied Sciences 13 (6), 3804 2023
Citations: 1