@mustaphasalihu6773@gmail.com
Lecturer, School of Sciences, Department of Chemistry
Shehu Shagari College of Education Sokoto, Nigeria
The use of plants in the management of snakebite has been an old practice especially among the populace in snake endemic regions in South East Asia and sub-Saharan Africa including Nigeria. Communities in these countries heavily rely on these plants due to easy access, acceptability and affordability. Catunaregam nilotica is a Nigerian medicinal plant commonly employed in the management of snakebite by some communities in North Western part of Nigeria without scientific validation. Preliminary screening of the plant against PLA2 enzyme has validated the antisnake venom activity of the plant by inhibiting the lethal actions of the enzyme from Naja nigricollis by 100 %. The black-necked spitting cobra (Naja nigricollis), the puff adder (Bitis arientans), and the carpet viper (Echis ocellatus) are the three poisonous snake species that are most frequently encountered in Nigeria. The main objective is to find a substance that can be developed into a dosage form to treat snake venom victims