Muhammad Shahid

Scopus Publications

Bukiniczia cabulica (Boiss.) Lincz. ameliorate diabetes-induced neuropathy: analgesic, anti-diabetic and anti-neuropathic using enzyme inhibitory, molecular docking and in-vivo studies
Zeeshan Ahmad, Mushtaq Ahmad Mir, Muhammad Shahid, Nasreena Bashir, Alam Zeb, Mehreen Ghufran, Falak Naz, Muhammad Ayaz
Inflammopharmacology, 2026
Phytochemical Profiling and Evaluation of the Anti-inflammatory and Antinociceptive Effects of Lilium polyphyllum Bulb Using In Silico, In Vitro and In Vivo Models
Haider Ali, Shafiq Ur Rahman, Umair Sayad, Atif Ali Khan Khalil, Muzaffar Abbas, Muhammad Shahid
Journal of Pharmaceutical Innovation, 2026
RETRACTED: Norfloxacin Loaded Lipid Polymer Hybrid Nanoparticles for Oral Administration: Fabrication, Characterization, In Silico Modelling and Toxicity Evaluation (Pharmaceutics, (2021), 13, 10, (1632), 10.3390/pharmaceutics13101632)
Muhammad Asghar Khan, Shahzeb Khan, Mohsin Kazi, Sultan M. Alshehri, Muhammad Shahid, Shafi Ullah Khan, Zahid Hussain, Muhammad Sohail, Muhammad Shafique, Hajra Afeera Hamid, Mahwish Kamran, Abdelbary Elhissi, Muhammad Wasim, Hnin Ei Thu
Pharmaceutics, 2025
The journal retracts the article “Norfloxacin Loaded Lipid Polymer Hybrid Nanoparticles for Oral Administration: Fabrication, Characterization, In Silico Modelling and Toxicity Evaluation” [...]
Novel efficacy of pregnane and flavonoid glycosides from Desmidorchis flava in in vivo nociceptive and inflammatory paradigms and their target prediction by cheminformatics approach
Ajmal Khan, Hamdy Kashtoh, Najeeb Ur Rehman, Muhammad Shahid, Irfan Ullah, Asaad Khalid, Afnan Jan, Sobia Ahsan Halim, Kwang-Hyun Baek, Ahmed Al-Harrasi
Natural Product Research, 2025
Inflammation is associated with multiple life-threatening conditions. Desmidorchis flava is an edible plant and traditionally used for managing various diseases. Three novel molecules, namely desmiflavaside-C (1), nizwaside (2), and desmiflanoside (3) were isolated from Desmidorchis flava, and their structures were confirmed by mass spectrometry and through reported literature. These compounds were in vivo examined for antinociceptive (tonic visceral nociception) and anti-inflammatory (carrageenan induced paw edema) activities. Significant antinociceptive potential was demonstrated by compound 1 at 0.5 and 1 mg/kg doses followed by compounds 2 and 3. At similar doses, significant anti-inflammatory activity was noted for all the tested compounds. Their antinociceptive and anti-inflammatory activities were comparable to the reference standards. In silico predicted binding modes suggests that these compounds may target allosteric sites of COX-1 and COX-2 enzymes to elicit their anti-inflammatory activities. These isolated natural products may have therapeutic potential in conditions afflicted with pain and inflammation.
Galegine, a Bioprivileged Alkaloid from Tithonia tubaeformis: Antipyretic Activity Insights
Noor Ul Ain Nawaz, Muhammad Saeed, Shaheen Faizi, Irfan Ali, Muhammad Shafiq, Muhammad Shahid, Fazle Rabbi, Fahim Ullah Khan, Rabeea Sharif, Zaheer Ul-Haq, Khalid Mohammed Khan, Hassan A. Hemeg, Waleed Al Abdulmonem, Abdullah S. M. Aljohani, Abdur Rauf
Current Topics in Medicinal Chemistry, 2025
Background: In continuation of our chemical and biological work on Tithonia tubaeformis, we evaluated the antipyretic activity of its extract which on fractionation gives a pure alkaloid galegine. Galegine a bioprivileged compound, is a hemiterpene bearing a guanidine group, which holds significant importance in medicinal chemistry. Biological activities such as antimicrobial, antidiabetic, anti-inflammatory, cardiovascular, anticancer, and antihypertensive, are often associated with guanidine-containing molecules. Objective: Given the biological importance of guanidine and in search of safe antipyretic agents from natural resources, an in vivo antipyretic activity of methanolic extract of T. tubaeformis and galegine was conducted to discover a potential hypothermic drug candidate from the plant. Methods: In vivo, the antipyretic activity of galegine (5, 25, and 50 mg/kg doses) and methanolic extract of T. tubaeformis (50, 100, and 200 mg/kg doses) was investigated by employing yeastinduced pyrexia in mice model. In silico molecular docking analysis involving target enzymes cyclooxygenase- 1 (COX-1), cyclooxygenase-2 (COX-2), and microsomal prostaglandin E synthase-1 (mPGES-1) was conducted. Additionally, galegine underwent ADME/T profiling using SwissADME and Protox-II tools to evaluate its bioavailability and safety profiles. Results: Both the extract and galegine showed a progressive dose-dependent reduction in body temperatures of the hyperthermic test animals. Moreover, in silico molecular docking analysis revealed significant binding affinities ranging from -3.58 to -5.41 kcal/mol. ADME/T analyses of galegine predicted its high drug-likeness and good safety profile. Conclusion: These biological and computational approaches supported T. tubaeformis in addressing pyrexia, with the isolated compound galegine emerging as a promising antipyretic agent.
6-Methoxyflavone antagonizes chronic constriction injury and diabetes associated neuropathic nociception expression
Muhammad Shahid, Fazal Subhan, Nisar Ahmad, Zia Ud Din, Ihsan Ullah, Shafiq Ur Rahman, Rahim Ullah, Umar Farooq, Javaid Alam, Noor Ul Ain Nawaz, Sudhair Abbas, Robert D.E. Sewell
Biochemical and Biophysical Research Communications, 2024
Evaluation of the Ameliorative Potential of 3,5-bis(2-hydroxyethyl)-1,3,5-thiadiazinane-2-thione against Scopolamine-Induced Alzheimer’s Disease
Shagufta, Gowhar Ali, Adnan Khan, Abdur Rasheed, Farah Deeba, Rahim Ullah, Muhammad Shahid, Haleema Ali, Rasool Khan, Najeebullah Shamezai, Naveed Sharif
International Journal of Molecular Sciences, 2024
Alzheimer’s disease (AD) is the most common neurodegenerative disorder, marked by cognitive impairment. Currently, the available treatment provides only symptomatic relief and there is a great need to design and formulate new drugs to stabilize AD. In the search for a new anti-Alzheimer’s drug, 3,5-bis(2-hydroxyethyl)-1,3,5-thiadiazinane-2-thione (THTT), a tetrahydro-2H-1,3,5-thiadiazine-2-thione derivative, was investigated against a scopolamine-induced Alzheimer’s model. The selected test compound was administered intraperitoneally in three doses (15 mg/kg, 30 mg/kg, and 45 mg/kg). The test compound exhibited an IC50 value of 69.41 µg/mL, indicating its ability to inhibit the acetylcholinesterase enzyme. An antioxidant DPPH assay revealed that the IC50 value of the test compound was 97.75 µg/mL, which shows that the test compound possesses antioxidant activity. The results of behavior tests including the Y-maze and elevated plus maze (EPM) show that the test compound improved short-term memory and spatial memory, respectively. Furthermore, in the Morris water maze (MWM) and light/dark model, the test compound shows improvements in learning and memory. Moreover, the results of histological studies show that the test compound can protect the brain against the harmful effects of scopolamine. Overall, the findings of our investigation suggest that our chosen test compound has disease-modifying and neuroprotective activities against the scopolamine-induced Alzheimer’s model. The test compound may be beneficial, subject to further elaborate investigation for anti-amyloid disease-modifying properties in AD.
Correction to: Domperidone nanocrystals with boosted oral bioavailability: fabrication, evaluation and molecular insight into the polymer-domperidone nanocrystal interaction (Drug Delivery and Translational Research, (2019), 9, 1, (284-297), 10.1007/s13346-018-00596-w)
Stalielson Tatenda Ndlovu, Naseem Ullah, Shahzeb Khan, Pritika Ramharack, Mahmoud Soliman, Marcel de Matas, Muhammad Shahid, Muhammad Sohail, Muhammad Imran, Syed Wadood Ali Shah, Zahid Hussain
Drug Delivery and Translational Research, 2024
Quantitative-HPLC-DAD polyphenols analysis, anxiolytic and cognition enhancing potentials of Sorbaria tomentosa Lindl. Rehder
Mater H. Mahnashi, Muhammad Ayaz, Yahya S. Alqahtani, Bandar A. Alyami, Muhammad Shahid, Omaish Alqahtani, Saeed M. Kabrah, Alam Zeb, Farhat Ullah, Abdul Sadiq
Journal of Ethnopharmacology, 2023
Isolation and Characterization of Lactobacillus crispatus, Lactococcus lactis, and Carnobacterium divergens as Potential Probiotic Bacteria from Fermented Black and Green Olives (Olea europaea): An Exploratory Study
Ayesha Saeed, Azra Yasmin, Mehreen Baig, Khalid Khan, Md Belal Bin Heyat, Faijan Akhtar, Zahra Batool, Abeer Kazmi, Abdul Wahab, Muhammad Shahid, Muhammad Arslan Ahmed, Sidra Abbas, Abdullah Y. Muaad, Amir Shahzad, Imtiaz Ahmad
Biomed Research International, 2023
Background. Table olives are becoming well recognized as a source of probiotic bacteria that might be used to create a health‐promoting fermented food product by traditional procedures based on the activities of indigenous microbial consortia present in local environments. Methodology. In the present study, the characterization of probiotic bacteria isolated from mince, chunks, and brine of fermented green and black olives (Olea europaea) was done based on morphological, biochemical, and physiological characteristics. Results. Bacterial isolates demonstrated excellent survival abilities at 25, 37, and 45°C and at a variable range of pH. However, the optimum temperature is 37 and the optimum pH is 7 for all three isolates. An antimicrobial susceptibility pattern was found among these isolates through the disc diffusion method. Most of the isolates were susceptible to streptomycin, imipenem, and chloramphenicol, whereas, amoxicillin showed resistance to these isolates, and variable results were recorded for the rest of the antibiotics tested. The growth of the isolates was optimum with the supplementation of 3% NaCl and 0.3% bile salt. The isolated bacteria were able to ferment skimmed milk into yogurt, hence making it capable of producing organic acid. Conclusion. Isolates of Lactobacillus crispatus MB417, Lactococcus lactis MB418 from black olives, and Carnobacterium divergens MB421 from green olives were characterized as potential candidates for use as starter cultures to induce fermentation of other probiotic food products.
Design, synthesis, in-vitro, in-vivo and ex-vivo pharmacology of thiazolidine-2,4-dione derivatives as selective and reversible monoamine oxidase-B inhibitors
Ridha Jadoon, Muhammad Aamir Javed, Muhammad Saeed Jan, Muhammad Ikram, Mater H. Mahnashi, Abdul Sadiq, Muhammad Shahid, Umer Rashid
Bioorganic and Medicinal Chemistry Letters, 2022
Cassia artemisiodes attenuates nociceptive and diabetes-induced neuropathic pain modalities apropos antioxidant and anti-inflammatory mechanisms
Rahim Ullah, Waseem Badshah, Gowhar Ali, Aman Ullah, Saleem Ullah Khan, Nisar Ahmad, Muhammad Shahid, Muhammad Naveed, Sami Ullah, Sudhair Abbas Bangash, Yusuf S. Althobaiti
Biomedicine and Pharmacotherapy, 2022
Muricazine, a new hydrazine derivative from Ranunculus muricatus L. with antioxidant, lipoxygenase and urease inhibitory activities
Naila Raziq, Muhammad Saeed, Muhammad Shaiq Ali, Muhammad Shahid, Mehreen Lateef, Salman Zafar
Natural Product Research, 2022
Flavonoids containing Vitex negundo extract displayed calcium channels blocking property underlying its anti-diarrheal and anti-spasmodic activities
Hadia Bibi, Niaz Ali, Muhammad Nabi, Ihsan Ullah Khan Altaf, Muhammad Shahid, Syeda Hjira bukhari, Zahid Rasul Niazi, Kifayat Ullah Shah
Main Group Chemistry, 2022
Folecitin Isolated from Hypericum oblongifolium Exerts Neuroprotection against Lipopolysaccharide-Induced Neuronal Synapse and Memory Dysfunction via p-AKT/Nrf-2/HO-1 Signalling Pathway
Umar Farooq, Muhammad Umar Khayam Sahibzada, Taous Khan, Rahim Ullah, Muhammad Shahid, Ameer Khusro, Veronique Seidel, Magda H. Abdellattif, Talha Bin Emran
Evidence Based Complementary and Alternative Medicine, 2022
Phytotherapeutic Approach in the Management of Cisplatin Induced Vomiting; Neurochemical Considerations in Pigeon Vomit Model
Ihsan Ullah, Fazal Subhan, Muhammad Shahid, Nisar Ahmad, Rehmat Shah, Javaid Alam, Ikram Ul Haq, Rahim Ullah, Muhammad Ayaz, H. C. Ananda Murthy
Oxidative Medicine and Cellular Longevity, 2022
Comparative in-vitro anti-inflammatory, anticholinesterase and antidiabetic evaluation: computational and kinetic assessment of succinimides cyano-acetate derivatives
Aini Pervaiz, Muhammad Saeed Jan, Syed Muhammad Hassan Shah, Ali Khan, Rehman Zafar, Bushra Ansari, Muhammad Shahid, Fida Hussain, Mohammad Ijaz Khan, Anwar Zeb, Syed Muhammad Mukarram shah
Journal of Biomolecular Structure and Dynamics, 2022
Antidiarrheal and antispasmodic activities of Trillium govanianum rhizomes extract: involvement of calcium channel blockade
Naveed Muhammad, Shafiq Ur Rahman, Hilal Uddin, Omer Shehzad, Muhammad Ismail, Niaz Ali, Aslam Khan, Muhammad Shahid, Abid Ullah, Shujaat Ahmad, Haya Hussain, Ikram ul Haq, Sara Vitalini, Marcello Iriti
Natural Product Research, 2022
Neuroprotective potentials of selected natural edible oils using enzyme inhibitory, kinetic and simulation approaches
Mater H. Mahnashi, Bandar A. Alyami, Yahya S. Alqahtani, Ali O. Alqarni, Muhammad Saeed Jan, Muhammad Ayaz, Farhat Ullah, Muhammad Shahid, Umer Rashid, Abdul Sadiq
BMC Complementary Medicine and Therapies, 2021
Pharmacological evaluation of the gabapentin salicylaldehyde derivative, gabapentsal, against tonic and phasic pain models, inflammation, and pyrexia
Nisar Ahmad, Fazal Subhan, Nazar Ul Islam, Muhammad Shahid, Naseem Ullah, Rahim Ullah, Muhammad Khurram, Muhammad Usman Amin, Shehla Akbar, Ihsan Ullah, Robert D. E. Sewell
Naunyn Schmiedeberg S Archives of Pharmacology, 2021
RETRACTED: Norfloxacin Loaded Lipid Polymer Hybrid Nanoparticles for Oral Administration: Fabrication, Characterization, In Silico Modelling and Toxicity Evaluation
Muhammad Khan, Shahzeb Khan, Mohsin Kazi, Sultan Alshehri, Muhammad Shahid, Shafi Khan, Zahid Hussain, Muhammad Sohail, Muhammad Shafique, Hajra Hamid, Mahwish Kamran, Abdelbary Elhissi, Muhammad Wasim, Hnin Thu
Pharmaceutics, 2021
A novel gabapentin analogue assuages neuropathic pain response in chronic sciatic nerve constriction model in rats
Nisar Ahmad, Fazal Subhan, Nazar Ul Islam, Muhammad Shahid, Naseem Ullah, Rahim Ullah, Shehla Akbar, Muhammad Usman Amin, Muhammad Khurram, Ihsan Ullah, Robert D.E. Sewell
Behavioural Brain Research, 2021
The antioxidant N-(2-mercaptopropionyl)-glycine (tiopronin) attenuates expression of neuropathic allodynia and hyperalgesia
Muhammad Shahid, Fazal Subhan, Nazar Ul Islam, Nisar Ahmad, Umar Farooq, Sudhair Abbas, Shehla Akbar, Ihsan Ullah, Naila Raziq, Zia Ud Din
Naunyn Schmiedeberg S Archives of Pharmacology, 2021
Correction to: The antioxidant N-(2-mercaptopropionyl)-glycine (tiopronin) attenuates expression of neuropathic allodynia and hyperalgesia (Naunyn-Schmiedeberg's Archives of Pharmacology, (2020), 10.1007/s00210-020-01995-y)
Muhammad Shahid, Fazal Subhan, Nazar Ul Islam, Nisar Ahmad, Umar Farooq, Sudhair Abbas, Shehla Akbar, Ihsan Ullah, Naila Raziq, Zia Ud Din
Naunyn Schmiedeberg S Archives of Pharmacology, 2021
Efficient design to fabricate smart Lumefantrine nanocrystals using DENA® particle engineering technology: Characterisation, in vitro and in vivo antimalarial evaluation and assessment of acute and sub-acute toxicity
Syed Muhammad Hassan Shah, Syed Muhammad Mukarram Shah, Shahzeb Khan, Farhat Ullah, Syed Wadood Ali Shah, Mehreen Ghias, Muhammad Shahid, Hugh DC. Smyth, Zahid Hussain, Muhammad Sohail, Abdelbary Elhissi, Mohammad Isreb
Journal of Drug Delivery Science and Technology, 2021
Neuroprotective Studies on Polygonum hydropiper L. Essential Oils Using Transgenic Animal Models
Xin Tong, Xiaoling Li, Muhammad Ayaz, Farhat Ullah, Abdul Sadiq, Muhammad Ovais, Muhammad Shahid, Mars Khayrullin, Ali Hazrat
Frontiers in Pharmacology, 2021
Muriolide, a novel antioxidant lactone from Ranunculus muricatus
Naila Raziq, Muhammad Saeed, Muhammad Shaiq Ali, Mehreen Lateef, Muhammad Shahid, Shehla Akbar, Salman Zafar
Natural Product Research, 2021
Isolation of tyrosine derived phenolics and their possible beneficial role in anti-inflammatory and antioxidant potential of Tithonia tubaeformis
Noor Ul Ain Nawaz, Muhammad Saeed, Khalid Mohammed Khan, Irfan Ali, Huma Aslam Bhatti, Sabi-Ur-Rehman, Muhammad Shahid, Shaheen Faizi
Natural Product Research, 2021
Bioavailability and hepatoprotection enhancement of berberine and its nanoparticles prepared by liquid antisolvent method
Muhammad Umar Khayam Sahibzada, Muhammad Zahoor, Abdul Sadiq, Fazl ur Rehman, Amal M. Al-Mohaimeed, Muhammad Shahid, Sumaira Naz, Riaz Ullah
Saudi Journal of Biological Sciences, 2021
Isolation, characterization and neuroprotective activity of folecitin: An in vivo study
Umar Farooq, Taous Khan, Shahid Ali Shah, Md. Sanower Hossain, Yousaf Ali, Rahim Ullah, Naila Raziq, Muhammad Shahid, Raffaele Capasso
Life, 2021
Piroxicam loaded polymer hybrid microspheres based tablets with modified release kinetics: Development, characterization and in vivo evaluation
Hamid, Hajra Afeera, Khan, Shahzeb, Shah, Syed Muhammad Noor, Asghar, Muhammad., Shahid, Muhammad, et al.
Pakistan Journal of Pharmaceutical Sciences, 2021
Efficacy assessment of salicylidene salicylhydrazide in chemotherapy associated peripheral neuropathy
Lala Rukh, Gowhar Ali, Rahim Ullah, Nazar Ul Islam, Muhammad Shahid
European Journal of Pharmacology, 2020
Cholinesterase's Enzymes Inhibition and Michaelis-Menten Kinetics Studies on Ethnomedicinally Important Plant Chenopodium botrys
Journal of Food Health and Bioenvironmental Science, 2020
Exogenous factors affecting growth of Aspergillus species
Omer Naseer, Jawaria Ali Khan, Muhammad Ovais Omer, Junaid Naseer, Muhammad Luqman Sohail, Muhammad Asif Munir, Muhammad Usman Saleem, Muhammad Imran, Muhammad Shahid
Indian Journal of Animal Research, 2020
Potential role of plant extracts and phytochemicals against foodborne pathogens
Farhat Ullah, Muhammad Ayaz, Abdul Sadiq, Farman Ullah, Ishtiaq Hussain, Muhammad Shahid, Zhanibek Yessimbekov, Anjana Adhikari-Devkota, Hari Prasad Devkota
Applied Sciences Switzerland, 2020
6-Methoxyflavanone abates cisplatin-induced neuropathic pain apropos anti-inflammatory mechanisms: A behavioral and molecular simulation study
Shehla Akbar, Fazal Subhan, Muhammad Shahid, Abdul Wadood, Naila Shahbaz, Umar Farooq, Muhammad Ayaz, Naila Raziq
European Journal of Pharmacology, 2020
Enhancement of bioavailability and hepatoprotection by silibinin through conversion to nanoparticles prepared by liquid antisolvent method
Muhammad Umar Khayam Sahibzada, Abdul Sadiq, Muhammad Zahoor, Sumera Naz, Muhammad Shahid, Najam Afaq Qureshi
Arabian Journal of Chemistry, 2020
The flavonoid 6-hydroxyflavone prevention of cisplatin-induced nephrotoxicity
Zia Ud Din, Syed Umer Farooq, Muhammad Shahid, Osama Alghamdi, Nawwaf Al‐Hamoudi, et al.
Histology and Histopathology, 2020
Engineering of naproxen loaded polymer hybrid enteric microspheres for modified release tablets: Development, characterization, in silico modelling and in vivo evaluation
Hajra Afeera Hameed, Shahzeb Khan, Muhammad Shahid, Riaz Ullah, Ahmed Bari, Syed Saeed Ali, Zahid Hussain, Muhammad Sohail, Shafi Ullah Khan, Thet Thet Htar
Drug Design Development and Therapy, 2020
Comparative cholinesterase, α-glucosidase inhibitory, antioxidant, molecular docking, and kinetic studies on potent succinimide derivatives
Ashfaq Ahmad, Farhat Ullah, Abdul Sadiq, Muhammad Ayaz, Muhammad Saeed Jan, Muhammad Shahid, Abdul Wadood, Fawad Mahmood, Umer Rashid, Riaz Ullah, Muhammad Umar Khayam Sahibzada, Ali S Alqahtani, Hafiz Majid Mahmood
Drug Design Development and Therapy, 2020
Gummy gold and silver nanoparticles of apricot (Prunus armeniaca) confer high stability and biological activity
Nazar Ul Islam, Raza Amin, Muhammad Shahid, Muhammad Amin
Arabian Journal of Chemistry, 2019
Pistacia integerrima gall extract mediated green synthesis of gold nanoparticles and their biological activities
Nazar Ul Islam, Kamran Jalil, Muhammad Shahid, Naveed Muhammad, Abdur Rauf
Arabian Journal of Chemistry, 2019
Green synthesis and biological activities of gold nanoparticles functionalized with Salix alba
Nazar Ul Islam, Kamran Jalil, Muhammad Shahid, Abdur Rauf, Naveed Muhammad, Ajmal Khan, Muhammad Raza Shah, Muhammad Atif Khan
Arabian Journal of Chemistry, 2019
Efficacy of a topical gabapentin gel in a cisplatin paradigm of chemotherapy-induced peripheral neuropathy
Muhammad Shahid, Fazal Subhan, Nisar Ahmad, Robert D. E. Sewell
BMC Pharmacology and Toxicology, 2019
Phytochemical, pharmacological and therapeutic profile of Bacopa monnieri: A prospective complementary medicine
Natural Medicines Clinical Efficacy Safety and Quality, 2019
Domperidone nanocrystals with boosted oral bioavailability: fabrication, evaluation and molecular insight into the polymer-domperidone nanocrystal interaction
Stalielson Tatenda Ndlovu, Naseem Ullah, Shahzeb Khan, Pritika Ramharack, Mahmoud Soliman, Marcel de Matas, Muhammad Shahid, Muhammad Sohail, Muhammad Imran, Syed Wadood Ali Shah, Zahid Hussain
Drug Delivery and Translational Research, 2019
Flavonoids as prospective neuroprotectants and their therapeutic propensity in aging associated neurological disorders
Muhammad Ayaz, Abdul Sadiq, Muhammad Junaid, Farhat Ullah, Muhammad Ovais, Ikram Ullah, Jawad Ahmed, Muhammad Shahid
Frontiers in Aging Neuroscience, 2019
Synthesis of pyrrolidine-2,5-dione based anti-inflammatory drug: In vitro COX-2, 5-LOX inhibition and in vivo anti-inflammatory studies
Latin American Journal of Pharmacy, 2019
Nephroprotective effect of berberis baluchistanica against gentamicin-induced nephrotoxicity in rabbit
Samreen Pervez, Muhammad Saeed, Haroon Khan, Muhammad Shahid, Irfan Ullah
Bangladesh Journal of Pharmacology, 2018
Multifunctional theranostic applications of biocompatible green-synthesized colloidal nanoparticles
Muhammad Ovais, Ali Talha Khalil, Abida Raza, Nazar Ul Islam, Muhammad Ayaz, Muthupandian Saravanan, Muhammad Ali, Irshad Ahmad, Muhammad Shahid, Zabta Khan Shinwari
Applied Microbiology and Biotechnology, 2018
Dexibuprofen nanocrystals with improved therapeutic performance: fabrication, characterization, in silico modeling, and in vivo evaluation
Naseem Ullah, Shahzeb Khan, Shaimaa Ahmed, Thirumala Govender, Hani S Faidah, Marcel de Matas, Muhammad Shahid, Muhammad Usman Minhas, Muhammad Sohail, Muhammad Khurram
International Journal of Nanomedicine, 2018
Suppression of Cisplatin-induced vomiting by Cannabis sativa in pigeons: Neurochemical evidences
Ihsan Ullah, Fazal Subhan, Javaid Alam, Muhammad Shahid, Muhammad Ayaz
Frontiers in Pharmacology, 2018
Repair of a Tibiotarsal Fracture in a Pomeranian Goose (Anser anser) with a Locking Plate
Pavel Slunsky, Janine Weiß, Alexander Haake, Muhammad Shahid, Leo Brunnberg, Kerstin Müller
Journal of Avian Medicine and Surgery, 2018
HPLC-DAD finger printing, antioxidant, cholinesterase, and α-glucosidase inhibitory potentials of a novel plant Olax nana
Muhammad Ovais, Muhammad Ayaz, Ali Talha Khalil, Sayed Afzal Shah, Muhammad Saeed Jan, Abida Raza, Muhammad Shahid, Zabta Khan Shinwari
BMC Complementary and Alternative Medicine, 2018
Efficacy of β-glucans and manna oligosaccharides (Yeast cell wall) and hydrated sodium calcium aluminosilicate (HSCAS) in preventing aflatoxicosis in bovine calves
Omer Naseer, Jawaria Khan, Muhammad Khan, Muhammad Omer, Muhammad Avais, Muhammad Sohail, Muhammad Saleem, Muhammad Shahid
Indian Journal of Animal Research, 2018
Bioactive chromone constituents from Vitex negundo alleviate pain and inflammation
Ajmal Khan, Sadia Naz, Umar Farooq, Muhammad Shahid, Irfan Ullah, Iftikhar Ali, Abdur Rauf, Yahia Mabkhot
Journal of Pain Research, 2018
Novel hydroquinone derivatives alleviate algesia, inflammation and pyrexia in the absence of gastric ulcerogenicity
Khwaja Fawad, Nazar Ul Islam, Fazal Subhan, Muhammad Shahid, Gowhar Ali, Faiz-Ur Rahman, Wajahat Mahmood, Nisar Ahmad
Tropical Journal of Pharmaceutical Research, 2018
Prunus armeniaca and prunus domestica gums: Exploring their synergistic binding potential in tablets
Latin American Journal of Pharmacy, 2018
Gabapentin and its salicylaldehyde derivative alleviate allodynia and hypoalgesia in a cisplatin-induced neuropathic pain model
Nisar Ahmad, Fazal Subhan, Nazar Ul Islam, Muhammad Shahid, Faiz Ur Rahman, Robert D.E. Sewell
European Journal of Pharmacology, 2017
The flavonoid 6-methoxyflavone allays cisplatin-induced neuropathic allodynia and hypoalgesia
Muhammad Shahid, Fazal Subhan, Nisar Ahmad, Robert D.E. Sewell
Biomedicine and Pharmacotherapy, 2017
Neuroprotective effect of Bacopa monnieri against morphine-induced histopathological changes in the cerebellum of rats
Pakistan Journal of Pharmaceutical Sciences, 2017
Anti-Alzheimer's studies on ß-sitosterol isolated from Polygonum hydropiper L.
Muhammad Ayaz, Muhammad Junaid, Farhat Ullah, Fazal Subhan, Abdul Sadiq, Gowhar Ali, Muhammad Ovais, Muhammad Shahid, Ashfaq Ahmad, Abdul Wadood, Mohamed El-Shazly, Nisar Ahmad, Sajjad Ahmad
Frontiers in Pharmacology, 2017
GC-MS analysis and gastroprotective evaluations of crude extracts, isolated saponins, and essential oil from Polygonum hydropiper L.
Muhammad Ayaz, Muhammad Junaid, Farhat Ullah, Abdul Sadiq, Muhammad Shahid, Waqar Ahmad, Ihsan Ullah, Ashfaq Ahmad, Nawazish-i-Husain Syed
Frontiers in Chemistry, 2017
Corrigendum: GC-MS analysis and gastroprotective evaluations of crude extracts, isolated saponins, and essential oil from polygonum hydropiper L. (Front. Chem., (2017), 5, 58, 10.3389/fchem.2017.00058)
Muhammad Ayaz, Muhammad Junaid, Farhat Ullah, Abdul Sadiq, Muhammad Shahid, Waqar Ahmad, Ihsan Ullah, Ashfaq Ahmad, Nawazish-i-Husain Syed
Frontiers in Chemistry, 2017
A bacosides containing Bacopa monnieri extract alleviates allodynia and hyperalgesia in the chronic constriction injury model of neuropathic pain in rats
Muhammad Shahid, Fazal Subhan, Nisar Ahmad, Ihsan Ullah
BMC Complementary and Alternative Medicine, 2017
A Novel Pregabalin Functionalized Salicylaldehyde Derivative Afforded Prospective Pain, Inflammation, and Pyrexia Alleviating Propensities
Nisar Ahmad, Fazal Subhan, Nazar Ul Islam, Muhammad Shahid, Faiz Ur Rahman, Khwaja Fawad
Archiv Der Pharmazie, 2017
A multi-target therapeutic potential of Prunus domestica gum stabilized nanoparticles exhibited prospective anticancer, antibacterial, urease-inhibition, anti-inflammatory and analgesic properties.
Nazar Ul Islam, Raza Amin, Muhammad Shahid, Muhammad Amin, Sumera Zaib, Jamshed Iqbal
BMC Complementary and Alternative Medicine, 2017
Topical gabapentin gel alleviates allodynia and hyperalgesia in the chronic sciatic nerve constriction injury neuropathic pain model
M. Shahid, F. Subhan, N. Ahmad, G. Ali, S. Akbar, K. Fawad, R.D.E. Sewell
European Journal of Pain United Kingdom, 2017
Erratum: Synthetic and natural antioxidants attenuate cisplatin-induced vomiting [BMC pharmacol toxicol., 18, 4, (2017) (1-11)]
Javaid Alam, Fazal Subhan, Ihsan Ullah, Muhammad Shahid, Gowhar Ali, Robert D. E. Sewell
BMC Pharmacology and Toxicology, 2017
Synthetic and natural antioxidants attenuate cisplatin-induced vomiting
Javaid Alam, Fazal Subhan, Ihsan Ullah, Muhammad Shahid, Gowhar Ali, Robert D. E. Sewell
BMC Pharmacology and Toxicology, 2017
A new glycosidic antioxidant from Ranunculus muricatus L. (Ranunculaceae) exhibited lipoxygenasae and xanthine oxidase inhibition properties
Naila Raziq, Muhammad Saeed, Muhammad Shaiq Ali, Salman Zafar, Muhammad Shahid, Mehreen Lateef
Natural Product Research, 2017
Characterization of 6-methoxyflavanone as a novel anxiolytic agent: A behavioral and pharmacokinetic approach
Shehla Akbar, Fazal Subhan, Nasiara Karim, Urooj Aman, Sami Ullah, Muhammad Shahid, Nisar Ahmad, Khwaja Fawad, Robert D.E. Sewell
European Journal of Pharmacology, 2017
Essential oil composition of mentha piperita L. And its antimicrobial effects against common human pathogenic bacterial and fungal strains
Pharmacologyonline, 2016
Biochemical and antimicrobial properties of citrus peel waste
Pharmacologyonline, 2016
6-Methoxyflavanone attenuates mechanical allodynia and vulvodynia in the streptozotocin-induced diabetic neuropathic pain
Shehla Akbar, Fazal Subhan, Nasiara Karim, Muhammad Shahid, Nisar Ahmad, Gowhar Ali, Wajahat Mahmood, Khwaja Fawad
Biomedicine and Pharmacotherapy, 2016
Olanzapine induced biochemical and histopathological changes after its chronic administration in rats
Rehmat Shah, Fazal Subhan, Gowhar Ali, Ihsan Ullah, Sami Ullah, Muhammad Shahid, Nisar Ahmad, Khwaja Fawad
Saudi Pharmaceutical Journal, 2016
Development of fixed dose combination tablets of aripiprazole plus divalproex sodium and their simultaneous determination using HPLC-UV
Zia Ahmed, Fazal Subhan, Saba Ahmed, Qazi Abdur Rasheed, Sagheer Ahmed, Muhammad Shahid, Saeed Farooq
Drug Development and Industrial Pharmacy, 2016
Beneficial Effects of Trillium govanianum Rhizomes in Pain and Inflammation
Shafiq Ur Rahman, Achyut Adhikari, Muhammad Ismail, Muhammad Raza Shah, Muhammad Khurram, Muhammad Shahid, Farman Ali, Abdul Haseeb, Fazal Akbar, Marcello Iriti
Molecules Basel Switzerland, 2016
Larynx trauma and hyoid bone fracture after bite injury in dog: Case report
George Manchi, Mathias M. Brunnberg, Muhammad Shahid, Ahmad Al Aiyan, Leo Brunnberg, Silke Stein
Frontiers in Veterinary Science, 2016
Pharmacological screening of Monotheca buxifolia (Falc.) A. DC. for antinociceptive, anti-inflammatory and antipyretic activities
Irfan Ullah, Jamshaid Ali Khan, Muhammad Shahid, Ajmal Khan, Achyut Adhikari, Peer Abdul Hannan, Ibrahim Javed, Faisal Shakeel, Umar Farooq
BMC Complementary and Alternative Medicine, 2016
Beneficial effects of Trillium govanianum rhizomes in pain and inflammation
Shafiq Ur Rahman, Achyut Adhikari, Muhammad Ismail, Muhammad Raza Shah, Muhammad Khurram, Muhammad Shahid, Farman Ali, Abdul Haseeb, Fazal Akbar, Marcello Iriti
Molecules, 2016
Passiflora incarnata attenuation of neuropathic allodynia and vulvodynia apropos GABA-ergic and opioidergic antinociceptive and behavioural mechanisms
Urooj Aman, Fazal Subhan, Muhammad Shahid, Shehla Akbar, Nisar Ahmad, Gowhar Ali, Khwaja Fawad, Robert D. E. Sewell
BMC Complementary and Alternative Medicine, 2016
Beneficial effects of Bacopa monnieri extract on opioid induced toxicity
Muhammad Shahid, Fazal Subhan, Ihsan Ullah, Gowhar Ali, Javaid Alam, Rehmat Shah
Heliyon, 2016
Pharmacological basis for the use of Hypericum oblongifolium as a medicinal plant in the management of pain, inflammation and pyrexia
Naila Raziq, Muhammad Saeed, Muhammad Shahid, Naveed Muhammad, Haroon Khan, Farah Gul
BMC Complementary and Alternative Medicine, 2016
Isolation and molecular characterization of pasteurella multocida from commercial layer flocks suffering from respiratory syndromes
Journal of Animal and Plant Sciences, 2016
Pharmaceutical evaluation and toxicological quantification of heavy metals and adulterated allopathic contents in raw and finished dosage form of antihypertensive herbal products
Muhammad Asif Khan, Amir Badshah, Muhammad Shahid
African Journal of Traditional Complementary and Alternative Medicines, 2016
Hepatoprotective effect of Monotheca buxifolia fruit against antitubercular drugs-induced hepatotoxicity in rats
Irfan Ullah, Jamshaid Ali Khan, Achyut Adhikari, Muhammad Shahid
Bangladesh Journal of Pharmacology, 2016
A streptozotocin-induced diabetic neuropathic pain model for static or dynamic mechanical allodynia and vulvodynia: Validation using topical and systemic gabapentin
Gowhar Ali, Fazal Subhan, Muzaffar Abbas, Jehan Zeb, Muhammad Shahid, Robert D. E. Sewell
Naunyn Schmiedeberg S Archives of Pharmacology, 2015
Green synthesis and biological activities of gold nanoparticles functionalized with Citrus reticulata, Citrus aurantium, Citrus sinensis and Citrus grandis
Journal of the Chemical Society of Pakistan, 2015
Antinociceptive, muscle relaxant and sedative activities of gold nanoparticles generated by methanolic extract of Euphorbia milii
Nazar Ul Islam, Ibrahim Khan, Abdur Rauf, Naveed Muhammad, Muhammad Shahid, Mohammad Raza Shah
BMC Complementary and Alternative Medicine, 2015
GC/MS analysis, free radical scavenging, anticancer and β-glucuronidase inhibitory activities of Trillium govanianum rhizome
Shafiq ur Rahman, Muhammad Ismail, Muhammad Raza Shah, Marcello Iriti, Muhammad Shahid
Bangladesh Journal of Pharmacology, 2015
Comparative histopathology of acetaminophen induced hepatotoxicity in animal models of mice and rats
Pharmacologyonline, 2014
Erratum: Attenuation of Cisplatin-Induced Emetogenesis by Standardized Bacopa monnieri Extracts in the Pigeon: Behavioral and Neurochemical Correlations (Planta Medica (2014) 80:17 (1569-1579) DOI: 10.1055/s-0034-1383121)
Ihsan Ullah, Fazal Subhan, John Rudd, Khalid Rauf, Javaid Alam, Muhammad Shahid, Robert Sewell
Planta Medica, 2014
Attenuation of cisplatin-induced emetogenesis by standardized Bacopa monnieri extracts in the pigeon: behavioral and neurochemical correlations
Ihsan Ullah, Fazal Subhan, John Rudd, Khalid Rauf, Javaid Alam, Muhammad Shahid, Robert Sewell
Planta Medica, 2014
Protective effect of bacopa monniera methanol extract against carbon tetrachloride induced hepatotoxicity and nephrotoxicity
Pharmacologyonline, 2014
Synthetically modified bioisosteres of salicyl alcohol and their gastroulcerogenic assessment versus aspirin: Biochemical and histological correlates
Gowhar Ali, Fazal Subhan, Nazar Ul Islam, Nasir Ullah, Robert D. E. Sewell, Muhammad Shahid, Ikhtiar Khan
Naunyn Schmiedeberg S Archives of Pharmacology, 2014
Protective effect of bacopa monniera methanol extract against carbon tetrachloride induced hepatotoxicity and nephrotoxicity
Pharmacologyonline, 2014
Comparative evaluation of gastroulcerogenic potential of nitrogen isoforms of salicyl alcohol and aspirin in rats: Biochemical and histological study
Gowhar Ali, Fazal Subhan, Nazar Ul Islam, Nasir Ullah, Muhammad Shahid, Sami Ullah, Ihsan Ullah, Rehmat Shah, Ikhtiar Khan, Robert D. E. Sewell, Ghulam Abbas
Archives of Pharmacal Research, 2014

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