Mykola Kopytsya

@therapy.org.ua

The head of the department (Department of Prevention and Treatment of Emergency Conditions)
L.T. Malaya National Therapy Institute of the National Academy of Medical Sciences of Ukraine: Kharkiv, Kharkivs’ka Oblast’, UA

Mykola Kopytsya


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https://researchid.co/n_kopitsa
Cardiologist. Doctor of Medical Sciences (2004). Professor (2020). State Prize of Ukraine in Science and Technology (2019). Graduated from Kharkiv Medical Institute (1981). Since then, he has been working at the Institute of Therapy of the National Academy of Medical Sciences of Ukraine (Kharkiv): 1985–2002— Head of the Department of Resuscitation and Intensive Care, since 2005— Head of the Department of Prevention and Treatment of Emergency Conditions. The main studies focus on post-infarction remodelling processes, taking into account the state of the immune system and neurotransmitters, and their impact on the development of heart failure and ventricular arrhythmia.

EDUCATION

Kharkiv National Medical University: Kharkiv, Kharkivs’ka Oblast’, UA from 1975-09-01 to 1981-06-30

RESEARCH, TEACHING, or OTHER INTERESTS

Cardiology and Cardiovascular Medicine
60

Scopus Publications

Scopus Publications

  • Outcomes of heart failure with reduced, mildly reduced, or preserved ejection fraction: the ESC HF III registry
    Lars H Lund, Aldo P Maggioni, Maria G Crespo-Leiro, Cecile Laroche, Israel Gotsman, Belma Pojskic, Eleonora B Vataman, Lucica Grigorica, Hamayak Sisakian, Duska Glavas, Dulce A Brito, Stefan Anker, Ovidiu Chioncel, Gerasimos Filippatos, Mitja Lainscak, Theresa A McDonagh, Alexandre Mebazaa, Massimo Piepoli, Frank Ruschitzka, Gianluigi Savarese, Petar M Seferović, Marco Metra, Giuseppe Rosano, the ESC EORP HF III National Leaders, Investigators, A Vahanian, A Budaj, N Dagres, N Danchin, V Delgado, J Emberson, O Friberg, C P Gale, G Heyndrickx, B Iung, S James, A P Kappetein, A P Maggioni, N Maniadakis, K V Nagy, G Parati, A-S Petronio, M Pietila, E Prescott, F Ruschitzka, F Van de Werf, F Weidinger, U Zeymer, C P Gale, B Beleslin, A Budaj, O Chioncel, N Dagres, N Danchin, J Emberson, D Erlinge, M Glikson, A Gray, M Kayikcioglu, A P Maggioni, K V Nagy, A Nedoshivin, A-P Petronio, J W Roos-Hesselink, L Wallentin, U Zeymer, B A Popescu, D Adlam, A L P Caforio, D Capodanno, Ovidiu Chioncel, M Dweck, D Erlinge, Laurent Fauchier, Marek Gierlotka, M Glikson, Tina Hansen, J Hausleiter, B Iung, M Kayikcioglu, P Ludman, L H Lund, A P Maggioni, Julien Magne, S Matskeplishvili, B Meder, Julinda Mehilli, K V Nagy, A Nedoshivin, D Neglia, A A Pasquet, Eva Prescott, J W Roos-Hesselink, F J Rossello, S M Shaheen, A Torbica, B Iung, B Popescu, D Adlam, C Bouleti, A Caforio, D Capodanno, L Fauchier, M Gilard, S James, P Ludman, J Magne, A Pasquet, T Pilgrim, J Rossello, S Shaheen, AvTimoteo, A Torbica, U Zeymer, Marisa Crespo-Leiro, Petar Seferovic, Frank Ruschitzka, Gerasimos Filippatos, Alexandre Mebazaa, Massimo Piepoli, Andrew Coats, Stefan Anker, Theresa McDonagh, Mitja Lainscak, Giuseppe Rosano, Aldo Maggioni, Lars Lund, Ahmed Bennis, Andrejs Erglis, Andrzej Gackowski, Alena Kurlianskaya, Amina Rakisheva, Alex Simms, Barnabas Gellen, Bela Merkely, Candida Fonseca, Daniela Cassar Demarco, Duska Glavas, Eva Goncalvesova, Eleonora Vataman, Elizabeta Srbinovska Kostovska, Erkin Mirrakhimov, Gani Bajraktari, Grigorios Giamouzis, Artan Goda, Gulnaz Dadashova, Hamayak Sisakian, Hadi Skouri, Heli Tolppanen, Israel Gotsman, Jean Beissel, Jelena Celutkiene, Jose Manuel Garcia Pinilla, Larisa Dizdarevic-Hudic, Lars Lysgaard Gullestad, Leonid Voronkov, Magdy Abdelhamid, Micha T Maeder, Mitja Lainscak, Morten Schou, Massimo Francesco Piepoli, Marija Polovina, Milos Taborsky, Mikheil Tsverava, Naima Hammoudi, Ovidiu Chioncel, Petra Van Pol, Plamen Gatzov, Belma Pojskic, Petar M Seferovic, Rudolf Berger, Stefan Stoerk, Timur Abdullaev, Tiina Uuetoa, Vassilis Barberis, Vyacheslav Mareev, Wachter Rolf, Walter Droogne, Yuksel Cavusoglu, Zumreta Kušljugić, S Benkhedda, D Djermane, M Baouni, F Benouareth, K Mouzaoui, N Dahimene, S Mansouri, F Kerkouri, A Chibane, M Djouhri, S Benferhat, L Talbi, Y Bouhouita-Guermech, R Benkouar, A Boudrifa, H Elnaajer, K Bouasria, O Kassoul, Y Tir, D-E Nibouche, A Sik, A Bounah, N Hammoudi, G Sofiane, M Bouame, A Sayah, E Tebbache, A Kachenoura, F Daimellah, M T C Bouafia, M Bouafia, N Dammene Debbih, W Takdemt, T Manukyan, L Tumasyan, A Chilingaryan, A Stepanyan, L Tunyan, H Hayrapetyan, K Azaryan, M Tadevosyan, H Poghosyan, H Sisakian, G Martirosyan, L Sahakyan, M Hovhannisyan, S Pepoyan, A Kurlianskaya, D Salauyou, A Kozyrava, O Shatova, T Troyanova-Shchutskaia, M Vanderheyden, A Moya, H Batjoens, A-C Pouleur, O Gurne, E Tshilanda, F Severino, W Mullens, M Dupont, S Christiaens, C Claes, S Lenaerts, D Derthoo, M Dumoulein, S Naessens, I Senesael, M De Coninck, W Droogne, E Sels, V Servaes, P Troisfontaines, E Hoffer, M Melissopoulou, D Malmendier, M Massoz, S Jacquet, V Dinraths, E Begic, A Mujakovic, A Subo, A Selimagic, F Custovic, D Mackic, E Dzambasovic-Karaselimovic, A Cehajic, A Djozic, A Biscevic-Obradovic, F Kadic, E Hrvat, I Kurbasic, M Tuce, A Durak-Nalbantic, A Dzubur, E Jahic, S Sokolovic, Z Gljiva Gogic, K Aganovic, F Zvizdic, A Begic, N Resic, E Hodzic, M Halilcevic, M Vucijak Grgurevic, N Hadžibegic, N Sabanovic Bajramovic, S Miseljic, E Smajic, Z Kušljugic, L Dizdarevic-Hudic, K Kovacevic, D Loncar, M Kovacevic, M Selimovic, U Pajic, I Hudic, A Avdic, A Bijedic, A Brkic, D Mršic, E Becirovic, I Bijedic, B Pojskic, J Djelmic, M Ejubovic, L Pojskic, E Ramic, M Sammak, H Selimovic, E Stimjanin, M Sut, H Torlak, I Bisco, D Bogicevic, A Brkovic, R Salgado, A Silva, B Azeredo, D De Souza, I Couri, L Salgado, M Tokmakova, D Jovanovska, N Runev, B Stoimenov, E Manov, R Pancheva, V Kolev, V Mincheva, V Tsanova, O Eftimova, I Gruev, M Mintchev, V Stoyanovski, T Petrusheva, V Persic, M Barisic, D Raljevic, D Glavas, D Milicic, J A Borovac, T Zaninovic Jurjevic, J Sikic, V Persic, K Pesek, K Pesek, S Roginic, N Borsic, J Sikic, T Friscic, Z Planinic, T Christodoulides, S Kakoulli, V Barberis, T Michaelidou, H Hasan-Ali, M Abdel Ghany, A Halim, S Dimitry, P P S Selwanos, M Hassan, A-S M Sabry, Y A Abdelhady Ahmed, T Osman, M Eshak, M El Sayed, K Menyawi, A Roshdy, W El Kilany, A Abdeltawab, A R El Sayed, O Botrous, A El Bagoury, A Samir, H Kandil, M Hosny, M Abdelghany, M Abdelhamid, M K Shokry, S Essam, A Kamal, H Ammar, A Kamel, A Magdy, H Elnesr, M Amin, M M Yousif, A H Eladawy, M F Areed, M H Abdelnabi, A G Mahmoud, M F Abdelrahman, A Elbahry, A Saad, M Ali, T Uuetoa, S Udalova, T Anier, S Viks, B Veermäe, H Tolppanen, K Oksaharju, N Mewton, A Jobbé Duval, C Boiteux, C Bergerot, G Baudry, L Sebbag, M Buisson, D Mohamed-Said, F El Harrane, M Koenig, N El-Jonhy, A Galat, D Bodez, C Chalard, F Djelaili, S Guendouz, S Oghina, T Damy, M Idjellidaine, M Kharoubi, N Djefel, Y Sellah, R Pilato, J Inamo, A Monfort, N Ozier-Lafontaine, D Guijarro, T Fourme, A Monard, P Bouheret, M Salvat, A Boignard, C Augier, C Casset, M Maurin, E Plan, D Pollet, P Jourdain, E Berthelot, M T Bailly, N Hrynchyshyn, G Leprun, B Livarek, J-L Georges, N Baron, C Charbonnel, J-B Azowa, C Bachelet, P Cloitre, P Poret, S Braun, O Zid, G Kabalu, A Denizet Mulocher, C Bros, C Dericbourg, C Saint Andre, E Lefebvre, J-F Laine, G Terrien, J-C Amirault, D Lecuyer, M Rousseau, F Beauvais, A Cohen-Solal, D Logeart, N Bennacer, B Gellen, J-M Tartiere, F Challal, F Fellini, R Landes, A Elkeurti, C Genin, P Armangau, V Gardan, M Galinier, O Lairez, J Roncalli, C Biendel, C Delmas, C Delon, E Cariou, P Fournier, R Itier, A Karavidas, D Balta, C Mandila, E Velaoras, I N Karavidas, L Michalis, K Naka, A Bechlioulis, L Lakkas, A Rammos, I Dimou, C Karvounis, M-A Bazbani, B Merkely, A Kosztin, N Nyolczas, D Vagany, I Juhasz, S Papp, M Szabo, E Szogi, A Pálinkás, I Szoko Csaszar, I Juhasz Nagy, S Rostásné Toth, T Habon, M Rabai, R Halmosi, R Gal, L Illes, S Kovacsne Levang, H Ali Farhan, I F Yaseen, E Radzishevsky, I Gotsman, O Ezra, T Levinas, I Nordkin, S Benyamin, Tel M Laufer-Perel, A Milwidsky, B Sadeh, D Wexler, O Havakuk, Y Arbel, M Revivo, S Sadon, M Metra, L Italia, L Rossi, Cassano Delle A Passantino, R Carbonara, C Rizzo, R La Gioia, M Milli, F Grossi, N D Brunetti, A Mallardi, M Correale, M Penco, G Patti, S Romano, R Petroni, E Salustri, S Minardi, S Scalvini, E Zanelli, A Olivares, P Agostoni, M Doldi, E Salvioni, P Gugliandolo, A Frisinghelli, C Calloni, C Cadeddu Dessalvi, M Deidda, A Peccianti, D Cocco, E Garau, A Cittadini, A Salzano, F Giallauria, G Crisci, R Lucci, A M Marra, V Valente, R D´assante, P Perrone-Filardi, P Gargiulo, S Paolillo, L Bardi, S Dellaversana, G Novo, A Ferlisi, D Adorno, E Bonni, E Corrado, F Sabatino, S Novo, M F Piepoli, B Matrone, G Halasz, L Moderato, V Pelizzoni, M Mancone, C Miotti, E Pagliaroli, M Magnocavallo, San Vito Al D Pavan, T Durat, V D’Onofrio, A Gardin, G Ganci, F Martinis, N Pezzutto, S Maier, G Sinagra, M Merlo, L Restivo, F Ramani, D Miani, M Baldassi, M Driussi, F L Ribichini, L Maritan, M Cicoira, M Lia, M Setti, M De Stefano, B Zholdin, G Mamedova, R Iznatova, Y Sim, R Tuleutayev, A Nurmukhambetova, I Yakupova, D Urazbekov, N Aidargaliyeva, A Akanova, A Makhmudova, A Tleules, G Nurbekova, M Akilbekova, S Nurlybai, A Aizhan, A Rakisheva, A Illyassova, A Dzholdasbekova, Z Ismagulova, A Kassenova, M Alkenova, A Aizhan, E Mirrakhimov, K Neronova, J Esenbekova, D Zaliaduonyte, J Laukaitiene, J Borkyte, A Mazutaviciute, R Norvilaite, J Celutkiene, E Paleviciute, J Simonavicius, L Gedvilaite, M Laukyte, E Lycholip, T Simbelyte, R G Xuereb, S Xuereb, W Camilleri, M Farrugia, J Fleri Soler, L-L Buttigieg, R Xuereb, A M Moore, D Cassar Demarco, C Attard, M Vella, I Grech, R Bonnici, R Buhagiar, G Buhagiar, T Farrugia, M O De Los Rios Ibarra, A Z Baños Velasco, F M Vizcaíno Rios, A Mendez, A Alvarez, C Guizar, S Leon Gonzalez, L Resendiz-Barron, E Vataman, D Bursacovschi, D Lisii, E Paraniuc, J Cazacu, M Dogot, N Botnari, L Grib, S Filimon, E Samohvalov, L Purteanu, A Grivenco, V Revenco, I Cabac-Pogorevici, I Cojuhari, A Bennis, S Chraibi, A El Makhlouf, S Ferhi, S Soulami, N Mouine, A Moustaghfir, K Adnan, C Bencheqroun, G Abidi, H Elmousalami, S Hajib, L Bouzoubaa, M Ghita, I Nassiri, S Abderrazak, Z Benchaouia, G Benhayoune, N Boughaidi, D Ghellab, A Sourat, B Menebhi, M Bensaoud, A El Ouazzani, A Lachhab, A Zakaria, F El Idrani, H Lachhab, N Elouafi, A Hbali, G Elmazani, I Alla, S Ztot, M Najat, B E El Younassi, I Asfalou, L Chami, M Raissouni, S Abdelali, A Benthami, A Drissi Kacemi, S Essadki, A Louali, K Bennis, Y Lididi, R Bouhouch, R Mesbahi, S Bouzidi Belmajdoub, I Ukpeh, R Basake, E-O Akpan, E Emmanuel, O Mbang, North M Gjerakaroska Radovikj, E Srbinovska Kostovska, I Mitevska Peovska, L Poposka, G Hogalmen, M German, L Lysgaard Gullestad, C Holt Bendz, O Haugene, E Bjorkelund, K Mizia-Stec, K Bula, J Nessler, A Gackowski, A Siniarski, M Kabat, P Rubis, A Karabinowska, E Dziewiecka, S Wisniowska-Smialek, M Lelonek, A Cieslak, A Klaus, J Szulc, K Drazek, K A Nguyen, M Kiedrowska, A Bielecka-Dabrowa, M Pyziak Stepien, M Rybak, P Leczycki, P Chrusciel, A Wittczak, M Banach, A Chuda, A Szwedzinska, M Rembek Wieliczko, D Mrozowska, F Pawliczak, J Lewek, M Maciejewski, A Cichocka-Radwan, A Bikiewicz, K Janikowski, J Szponar, A Kujawa, A Sutkowska, B Cebulak, K Pirog, J Wieczorek, M Suchecka, S Goliszek, M Gierlotka, E Cierpiala, J Bugajski, J Plonka, K Rekucki, E Straburzynska-Migaj, D Budzynski, M Gasiorowski, M Dudek, G Skonieczny, A Dolacinska, A Metzgier Gumiela, A Stawicka, M Rolirad, A Kaplon-Cieslicka, M Wawrzacz, K Ozieranski, M Kleszczewska, A Tyminska, R J Gil, A Pawlak, M Wozniak, M Pietraszek, A Nazaruk, A Bobel, A Smolarczyk, D Wiligorska, D Ziecik, J Latek, K Byczkowska, P Leszek, J Urbanowski, N Wiligorska, Z Kalarus, T Kukulski, A Swiatkowski, M Szulik, N Kandora, Zielona P Jesionowski, T Zemleduch, A Kasperowicz, K Sosinska, A Camacho, R Fernandes, H Costa, C Tavares Aguiar, A Tralhão, A Ventosa, C Brízido, C Strong, B Rocha, G Cunha, D Brito, A Nunes-Ferreira, I Aguiar Ricardo, R Santos, S Pereira, T Rodrigues, J Agostinho, J Brito, J Rigueira, N Cunha, P António, P Morais, D Cravo, C Fonseca, C Rodrigues, I Araujo, J Presume, M Proenca, S Maltes, B Moura, E Barreira, P Janeira, C Ferrao, J Silva-Cardoso, A Sousa, B Mena, X Resende, M Fonseca, M Braga, M Campelo, E Moreira, P Araújo, P Diogo, R Pinto, S Amorim, B Moura, Baia C Pop, A Iosip, C-J Sinescu, N Avram, D G Baltag, N Samoila, M Dorobantu, A Scafa Udriste, A Scarlatescu, N Oprescu, O Fronea Gheorghe, O Chioncel, L Antohi, O Geavlete, G-A Dan, I-C Daha, S Bari, C Delcea, D C Ciuculete, I Lupasteanu, C Stanescu, A Vijan, C Militaru, A Giuca, G C Moise, E G Pascu, L Grigorica, C Corciova, Targu T Benedek, M Chitu, N Rat, R Hodas, D Opincariu, I S Benedek, D Lighezan, A C Florea, R Buzas, V Ivan, Russian A Molchanova, M Piskareva, E Bulgakova, E Kudryashova, A Galyavich, L Baleeva, Z Galeeva, A Fendrikova, V Skibitskiy, Z Sokaeva, V Babayan, N Spiropulos, E V Resnik, A I Kovaleva, M S Komissarova, V A Lazarev, V Larina, Y Belenkov, Y Danilogorskaya, E Zheleznykh, E Privalova, I Ilgisonis, V Kaplunova, M Kozhevnikova, G Shakaryants, A Shchendrygina, A Yusupova, V Zektser, Z Kobalava, E Shavarova, L Karapetyan, G Gendlin, A Melekhov, I Zakharova, M Kuznetsova, M Yunyaeva, G Arutyunov, A Arutyunov, R Muradyan, S Golitsyn, E Gupalo, N Mironova, O Drapkina, R Myasnikov, T Pavlunina, V Dindikova, Y Mareev, E Andreenko, K Krupychka, M Kudryavtseva, O Kulikova, I Orlova, J Begrambekova, Nizhny N Vinogradova, I Fomin, N Koziolova, A Veclich, P Karavaev, A Chesnikova, O Kolomatskaya, V Gavrina, E Smirnova, A Karakiyan, I Budanova, M Sitnikova, A Kuular, M Trukshina, T Lelyavina, D Duplyakov, E Zorina, R Chernitsov, A Sergeeva, A Garganeeva, O Tukish, K Kopeva, V Aleksandrenko, A Surminova, A Tsareva, T Musurok, A Garkusha, A D Ristic, B Ivanovic, D Simic, M Ašanin, P M Seferovic, J Simic, V Kovacevic, G Krljanac, D Matic, M Mihailovic, M Ostojic, M Polovina, M Tesic, D Djikic, D Simeunovic, I Petrovic Djordjevic, I Veljic, I Milinkovic, K Andjelkovic, A Uscumlic, D Sacic, M Dekleva Manojlovic, S Veljkovic, D Stefanovic, J Stevic, S Hinic, M Zdravkovic, A Dokovic, J Djokic, V Mudrenovic, V Popadic, S Klasnja, S Radovanovic, M Radovanovic, V Celic, A Ilic, N Blagojevic, D Bosnjakovic, D Toncev, Niš: S Apostolovic, D Stanojevic, S Milutinovic, Niska B Ilic, M Deljanin Ilic, L Nikolic, M Stojanovic, D Petrovic, D Simonovic, S Šaric, D Hristov, Sremska I Srdanovic, J Dejanovic, T Popov, S Cemerlic Maksimovic, S Dimic, S Keca, V Drljavic, D Bogdanovic, I Popov, J Pavic Poljak, E Goncalvesova, M Luknár, P Solik, M Pytliak, P Bojcík, Murska M Lainscak, N Cmor, E Dora, L Majc Hodoscek, A Vogrincic Cernezel, B Leskovar, T Furlan, A Milanovic, K Vrbinc Vrtek, S Poznic, V Grilj, M Režun, V Martinez Mateo, M J Fernandez Anguita, C Ortiz Cortés, A Valle Muñoz, H Morillas Climent, J Seller Moya, S Darnés Soler, S Cudini, S López Fernández, L Jordán Martínez, F Bermúdez Jiménez, La M Crespo Leiro, D Couto Mallon, E Barge Caballero, G Barge Caballero, M J Paniagua Martin, P Pardo Martinez, C Naya Leira, C Riveiro Rodriguez, M Martinez Castro, P Blanco Canosa, Z Grille Cancela, J M Garcia Pinilla, A Robles Mezcua, A Rodriguez Cordoba, C Cruzado Alvarez, L Morcillo Hidalgo, P Marquez Camas, A I Perez Cabeza, P Redondo-Gomez, M Robles Mezcua, J L Bonilla Palomas, L Lund, M Nygren, G Savarese, C Hage, E Jonsson, E Ottenblad, F Granstrom, H Lundberg, K Karlsson, Syrian Arab Y Bani Marjeh, A Abdin, F Alhussein, F Mgazeel, F Yavuz, A Karakus, Alanya A Coner, S Akinci, B Demirkan, O Akkus, A Genc, F O Arican Ozluk, H Harbalioglu, Y Cavusoglu, E Babayigit, E Sener, E I Yuce, H Altay, Ö Yildirimtürk, C Altin, B Kilicaslan, B Unal, H Acet, N Cetin, C Burak, D Karacimen, A Agacdiken Agir, Y U Celikyurt, A Celik, E E Sahin, O Sakarya, M Demir, O Basaran, A E Atas, O Khaniukov, I Vakaliuk, I Drapchak, V Sovtus, N Tymochko, O Prytuliak, V Tseluyko, N Matviichuk, M Kopytsya, T Storozhenko, I Rudyk, O Medentseva, D Babichev, L Voronkov, A Liashenko, I Rudenko, K Lazareva, N Sishkina, A Honcharuk, O Vasylenko, Y Antoniuk, M Dolzhenko, L Hrubyak, L Lobach, T Simagina, S Kozhuhov, N Dovganych, N Thor, M Danko, O Yarynkina, O Bazyka, A Parkhomenko, A Stepura, D Bilyi, O Irkin, O Dovhan, V Batushkin, D Poddyachaya, O Zharinov, B Todurov, I Lischuk, K Rudenko, V Zhebel, I Pashkova, L Sursaieva, Krivoy V Potabashniy, V Fesenko, O Markova, O Kniazieva, O Berezin, O Kremzer, United M Aldwaik, A Bolger, R Manley, V Garvey, T Abdullaev, S Mirzarakhimova, A Rasulov, A Karimov, H Gulomov, I Tsoy, R Kurbanova, R Bekbulatova, U Kamilova, D Tagaeva
    European Heart Journal, 2026
    Background and Aims To assess in-hospital and 1-year cause-specific outcomes in the contemporary European Society of Cardiology (ESC) Heart Failure (HF) III Registry. Methods Patients were enrolled in European or ESC affiliated countries and characterized in detail regarding clinical characteristics and cause-specific outcomes. Results Between 1 November 2018 and 31 December 2020, 10,162 patients were enrolled from 220 centres in 41 countries. Of these, 39% had acute HF (‘AHF’, age 70 [62–79] years, 36% women) and 61% had out-patient visit for HF [‘out-patient HF’, age 66 (58–75) years, 33% women]. Overall, 58% had HF with reduced ejection fraction (HFrEF), 17% HF with mildly reduced ejection fraction (HFmrEF), and 25% HF with preserved ejection fraction (HFpEF). In AHF, median [interquartile range (IQR)] duration of hospitalization was 9 (6–14) days, and 5.1% died in hospital (HFrEF 5.2%; HFmrEF 4.8%, HFpEF 3.4%). In AHF discharged alive and in out-patient HF, after a median (IQR) follow-up of 376 (360–432) days, all-cause, cardiovascular (CV), and unknown-cause mortality rates per 100 patient-years were as follows: AHF HFrEF: 19, 13, and 3.0 per 100 patient-years. The corresponding numbers were in AHF HFmrEF: 22, 11, and 6.3; AHF HFpEF: 16, 7.0, and 4.7; out-patient HFrEF: 6.6, 4.3, and 0.9; out-patient HFmrEF: 4.0, 2.6, and 0.8; out-patient HFpEF: 3.9, 1.7, and 1.2. At least one (re-)hospitalization for HF was experienced in 44% AHF HFrEF, 42% AHF HFmrEF, 36% AHF HFpEF, 21% out-patient HFrEF, 14% out-patient HFmrEF, and 18% out-patient HFpEF. Conclusions In HF in Europe and affiliated countries, in-hospital mortality was 5.1% and greater with lower ejection fraction. Among hospital survivors and out-patients over 1 year of follow-up, event rates per 100 patient-years varied for death, 3.9–22, CV death 1.7–13, and unknown cause of death 0.8–6.3. The percent of patients that were (re-)hospitalized for HF at least once over 1-year follow-up ranged 14–44% and was twice as high post-AHF compared with post-out-patient visit.
  • Macrophage migration inhibitory factor (MIF): can functional insights pave the way for future therapeutics in cardiovascular diseases?
    Tatyana Storozhenko, Olga Petyunina, Alexander Berezin, Mykola Kopytsya
    Expert Opinion on Therapeutic Targets, 2025
    INTRODUCTION: Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine involved in immune regulation, inflammation, and tissue homeostasis. Elevated MIF levels contribute to the progression of various cardiovascular diseases (CVDs), making it an attractive therapeutic target. However, the pleiotropic nature and complexity of MIF context-dependent effects pose significant challenges for clinical translation, but also offer unique opportunities to develop new precision medicine-based tools. AREAS COVERED: This review summarizes the biological functions of MIF and its homolog MIF-2 in CVD pathogenesis, along with the current landscape of therapies targeting MIF. We highlight recent preclinical findings, discuss ongoing controversies surrounding MIF's dual roles, and explore the potential of personalized approaches. EXPERT OPINION: MIF represents a promising yet complex target in cardiovascular medicine. Future success in clinical application will depend on the development of highly selective modulators, integration of patient stratification strategies and MIF-based interventions as part of multimodal cardiovascular care.
  • Prognostic significance of suppressor of tumorigenicity 2, endothelin-1, macrophage migration inhibitory factor, interleukin-6 and C-reactive protein in patients with acute myocardial infarction with ST-segment elevation and reduced glomerular filtration rate
    A. O. Bilchenko, M. P. Kopytsya, O. V. Petyunina, I. R. Vishnevska, I. V. Rodionova, K. A. Vishniakov, T. Y. Storozhenko
    Ukrainian Therapeutical Journal, 2024
    Acute myocardial infarction with ST‑segment elevation (STEMI) is one of the most severe forms of cardiovascular disease, requiring immediate diagnosis and treatment. Prognostic biomarkers play a crucial role in risk stratification and guiding therapeutic strategies in STEMI patients, particularly those with reduced glomerular filtration rate (GFR). Objective — to evaluate the prognostic significance of suppressor of tumorigenicity 2 (ST2), endothelin­1 (ET­1), macrophage migration inhibitory factor (MIF), interleukin­6 (IL­6), and C­reactive protein (CRP) in STEMI patients with reduced GFR compared to those with normal GFR for improved risk stratification and management. Materials and methods. This study was conducted on a cohort of 762 patients diagnosed with STEMI. The mean age of the patients was (60.5±10.5) years, with 74.7% being male. The glomerular filtration rate was calculated using the CKD­EPI 2021 formula. Patients were categorized into two groups: 246 with GFR <60 ml/min/1.73m2 and 516 with GFR ≥60 ml/min/1.73m2. Biomarker levels (ST2, ET­1, MIF, IL­6, CRP) were measured using enzyme­linked immunosorbent assay (ELISA) kits. Results. In patients with reduced GFR, ST2 and CRP levels were significantly higher than in patients with normal GFR (39.48 [26.49—80.71] and 33.78 [21.14—59.66] ng/ml, respectively, p=0.026 and 48 [36—96] and 24 [6—48] mg/l, p=0.015). The levels of MIF and IL‑6 were also increased in patients with reduced GFR, but the differences in these parameters were not statistically significant. No significant difference was recorded in ET‑1 levels between the groups. The analysis of ROC curves for ST2 revealed moderate prognostic accuracy in predicting survival in patients with reduced GFR (AUC=0.659; p=0.016). Conclusions. The results indicate the importance of ST2 as a prognostic marker in STEMI patients with reduced GFR. The use of these biomarkers in clinical practice can improve risk stratification and management in this patient group. Further research is warranted to develop individualized treatment approaches that consider the risks of cardiovascular events and renal dysfunction in STEMI patients.
  • Comparative analysis of subclinical anxiety-depressive syndrome in STEMI patients before and during active hostilities in Kharkiv Region, Ukraine
    O. V. Petyunina, M. P. Kopytsya, I. R. Vyshnevska, P. O. Petiunin
    Ukrainian Journal of Cardiology, 2024
    The aim – to assess subclinical emotional distress in patients with ST-Elevation Myocardial Infarction (STEMI) before and during the ongoing conflict in the Kharkiv Region. Materials and methods. The study encompassed 242 patients exhibiting subclinical emotional distress and hospitalized with STEMI at «L.T. Malaya TNI of NAMSU» before active conflict, compared with 65 patients during the conflict. Adherence to ethical standards was ensured, in line with the 1964 Helsinki Declaration, and the protocol received approval from the local ethics committee (Protocol № 8, dated 29.08.2016, and Protocol № 4, dated 12.05.2022). Participants completed the DASS-21 questionnaire, reflecting their emotional state 10–14 days prior, and received STEMI treatment as per current guidelines.Results. We showed that anxiety more frequent appeared during the active hostilities (p=0.0218). Depression had the influence on excessive smoking (p=0.0199), LV EF decrease (p=0.0057), LDL-C increase (p=0.0393). Anxiety and stress intrude into hypertension frequency (p=0.0171, p=0.0489) consequently as well as anxiety – on LDL-C increase (p=0.0068). All data of subclinical emotional distress during active hostilities associate with the frequency of smoking increase: p=0.0422 for depression, p=0.0275 for anxiety and p=0.0199 for stress. Depression associates with LVEF decrease (p=0.0267), the leucocytes count increase (p=0.0467), high frequency of hypertension (p=0.0410). Anxiety associates with higher heart rate (p=0.0277), depression and stress – with younger age (p=0.0369).Conclusions. Our research demonstrates close associations between the data of subclinical emotional distress both in patients with STEMI before and during the active hostilities in Kharkiv Region. Data were assessed with DASS-21 questionnaire on 10 –14 day prior the event. These results should be undertaken during general practitioner’s appointment to prevent further cardiovascular event.
  • The difficulty of revascularization at myocardial infarction with ST-segment elevation during the military conflict: clinical scenarios. Review
    M. P. Kopytsya, O. V. Petyunina, I. R. Vyshnevska
    Ukrainian Therapeutical Journal, 2023
    Russian military aggression against Ukraine challenged serious difficulties in the treatment of acute myocardial infarction with ST segment elevation (STEMI). Continuous stress, depression and insufficient pharmacotherapy resulted in the chronic coronary syndrome exacerbation, the increased number of STEMI cases and increased mortality because of the absence of timely myocardial reperfusion. The golden standard of the STEMI treatment is percutaneous coronary intervention (PCI), the result of which is the most effective reperfusion and patients’ survival. At the military conditions PCI possibility is restricted. The alternative to this method should be the fibrinolytic therapy, which has recently been rarely used as a reperfusion method in acute STEMI due to the availability of a network of catheter laboratories. The optimal variant of treatment at the condition of complicated logistical circumstances during the military time must be pharmacoinvasive strategy based on fibrinolysis and further PCI. Since the capabilities of reperfusion centers differ in the regions of Ukraine depending on the distance from the war zone, treatment strategies may be different. The main task in the STEMI treatment always must be the earliest renovation of myocardial circulation in the ischemic myocardium.The authors highlighted scenarios of STEMI treatment at the condition of military conflict where pharmacoinvasive strategy might have advantages in case of difficulties with providing quick access to percutaneous coronary intervention.When choosing a treatment strategy for acute STEMI, it is important to consider the specific conditions, the resources of the medical system, and the availability of medical care. The use of pharmacoinvasive strategy may be useful if the initial PCI is delayed beyond the recommended time, allowing for early reperfusion and improving treatment outcomes.
  • Soluble ST2 association with outcome of revascularization and the heart failure development in patients with acute myocardial infarction with ST segment elevation
    M. P. Kopytsya, Ya. V. Hilova, I. M. Kutya, Yu. V. Rodionova, L. L Petieniova
    Ukrainian Journal of Cardiology, 2023
    The aim – to study the relationship between the sST2 level and the degree of epicardial blood flow recovery and with the heart failure (HF) development in 6 month follow-up in patients with STEMI after PCI.Materials and methods. The study involved 61 patients with STEMI – 51 (83.6 %) males and 10 (16.4 %) females, with average age of 59.85±10.01 years. Standard clinical and biochemical parameters were determined, as well as sST2 level was measured by enzyme immunoassay using a reagent kit «Presage ST2 analysis, Critical Diagnosis» (USA) in all patients, on the first day of the disease. Patients were divided into two groups depending on the degree of blood flow recovery in a culprit artery (TIMI) The first group (n=12) included patients with TIMI 0, I, II, the second group (n=49) with TIMI III.Results and discussion. The sST2 level was significantly higher in the first hours of the disease in the group with unrepaired or decreased epicardial blood flow (TIMI 0–II) after PCI (p=0.003). ROC analysis showed that sST2 levels above 34.2 ng/ml, detected in the first hours of the disease, is an independent marker of adverse revascularization (TIMI 0–I) in patients with STEMI with a sensitivity of 92.3 % and a specificity of 62.5 %; the area under curve (the AUC) is 0.8 (95 % CI=0.651–0.873; p=0.001). When conducting a univariate (χ2=17.741; p=0.04) and multivariate (χ2=9.293; p=0.004) logistic analyzes, sST2 was a significant influencer of the unfavorable outcome of epicardial vascular revascularization (TIMI 0–ІІ).Conclusions. sST2 is highly associated with the degree of epicardial blood flow recovery in patients with STEMI and is of great clinical importance as diagnostic marker.
  • Myocardial Mechanical Dispersion Predicts Adverse Cardiac Remodeling in Patients with ST Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention
    Olga Petyunina
    Turk Kardiyoloji Dernegi Arsivi, 2023
    OBJECTIVE: The aim of the study was to investigate whether increased left ventricular mechanical dispersion is an early predictor for adverse cardiac remodeling in ST-segment elevation myocardial infarction patients who had post-percutaneous coronary intervention thrombolysis in myocardial infarction (TIMI) flow grade > 2. METHODS: A total of 119 post-percutaneous coronary intervention ST elevation myocardial infarction patients with TIMI flow grade >2 were prospectively included in the study. Left ventricular global longitudinal strain was quantified by 2-dimensional speckletracking echocardiography, and left ventricular mechanical dispersion was determined at baseline and after 1 year to assess adverse cardiac remodeling. The levels of circulating biomarkers were measured at the baseline. TIMI score and the Global Registry of Acute Coronary Events score systems were used to evaluate the prognosis of patients. RESULTS: Patients with high quartile versus low quartile of left ventricular mechanical dispersion exerted higher Global Registry of Acute Coronary Events and TIMI score grades, left ventricular endsystolic volume, global longitudinal strain, and levels of the N-terminal fragment of brain natriuretic peptide and lower left ventricular ejection fraction. Multivariate log regression showed that N-terminal fragment of brain natriuretic peptide > 953 pg/mL, global longitudinal strain > -8%, and high quartile of left ventricular mechanical dispersion remained independent predictors for adverse cardiac remodeling. Addition of left ventricular mechanical dispersion to the N-terminal fragment of brain natriuretic peptide improved the discriminative potency of the whole model. CONCLUSION: Measurement of left ventricular mechanical dispersion might be useful in determining the risk of adverse cardiac remodeling in post-percutaneous coronary intervention ST elevation myocardial infarction patients.
  • Lower Circulating Cell-Free Mitochondrial DNA Is Associated with Heart Failure in Type 2 Diabetes Mellitus Patients
    Tetiana Berezina, Mykola Kopytsya, Olga Petyunina, Alexander Berezin, Zeljko Obradovic, Lukas Schmidbauer, Michael Lichtenauer, Alexander Berezin
    Cardiogenetics, 2023
    Cell-free nuclear (cf-nDNA) and mitochondrial (cf-mDNA) DNA are released from damaged cells in type 2 diabetes mellitus (T2DM) patients, contributing to adverse cardiac remodeling, vascular dysfunction, and inflammation. The purpose of this study was to correlate the presence and type of cf-DNAs with HF in T2DM patients. A total of 612 T2DM patients were prescreened by using a local database, and 240 patients (120 non-HF and 120 HF individuals) were ultimately selected. The collection of medical information, including both echocardiography and Doppler imagery, as well as the assessment of biochemistry parameters and the circulating biomarkers, were performed at baseline. The N-terminal brain natriuretic pro-peptide (NT-proBNP) and cf-nDNA/cf-mtDNA levels were measured via an ELISA kit and real-time quantitative PCR tests, respectively. We found that HF patients possessed significantly higher levels of cf-nDNA (9.9 ± 2.5 μmol/L vs. 5.4 ± 2.7 μmol/L; p = 0.04) and lower cf-mtDNA (15.7 ± 3.3 μmol/L vs. 30.4 ± 4.8 μmol/L; p = 0.001) than those without HF. The multivariate log regression showed that the discriminative potency of cf-nDNA >7.6 μmol/L (OR = 1.07; 95% CI = 1.03–1.12; p = 0.01) was higher that the NT-proBNP (odds ratio [OR] = 1.10; 95% confidence interval [CI] = 1.04–1.19; p = 0.001) for HF. In conclusion, we independently established that elevated levels of cf-nDNA, originating from NT-proBNP, were associated with HF in T2DM patients.
  • The level of endothelin-1 in prognostiсation of adverse cardiac remodeling after ST-elevation myocardial infarction
    I. R. Vyshnevska, O. V. Petyunina, M. P. Kopytsya
    Ukrainian Therapeutical Journal, 2023
    Most patients have a good survival after myocardial infarction due to modern methods of treatment. However, certain disadvantages are still present today: the incidence of heart failure is increasing dramatically. Supervision those patients needs grate expenses, especially during the war. That is why it is continuing the search of the predictors important in the prognostication of heart failure.Objective — to determine the value of endothelin‑1 (ET‑1) on prediction of adverse cardiac remodeling in ST‑elevation myocardial infarction (STEMI) patients successfully treated with primary percutaneous coronary intervention.Materials and methods. We prospectively enrolled 162 individuals with STEMI who were successfully treated with primary percutaneous coronary intervention. The biomarkers (ET‑1, cardiac troponins) and echocardiographic parameters were evaluated at the baseline.Results. The study group was divided into two: with high and low ET‑1 level, based on median 2.75 pg/ml, which was the cutoff point with the highest combination of sensitivity and specificity calculated using receiver operating characteristic (ROC). ROC analysis demonstrated endothelin prognostic potential for left ventricle remodeling. The cut‑off was less than 2.97 pg/ml (sensitivity — 83%, specificity — 62%, area under curve (AUC) — 0.70, 95% confident interval 0.516—0.847, p=0.03). Endothelin biomarker was evaluated as a possible predictor of left ventricular remodeling using logistic regression analysis. Endothelin‑1 showed properties of predicting adverse cardiac remodeling (95% confident interval 0.696—0.956, AUC — 0.861, χ2=9.03, p=0.43).Conclusions. Determination of ET‑1 level will allow to use adequate medical management in adverse cardiac remodeling prognosis in STEMI patients to prevent heart failure development.
  • Predictive role of MMP-9 and MPO in patients with reduced glomerular filtration rate after acute coronary syndrome
    A.O. Bilchenko, M.P. Kopytsya, O.V. Petyunina, I.R. Vishnevskaya, Iu.V. Rodionova
    Emergency Medicine Ukraine, 2023
    Background. Coronary artery disease (CAD) persistently remains the leading cause of mortality globally. Given the severity and impact of this condition, researchers have been meticulously studying the pathogenesis of athe-rosclerosis, a principal cause behind CAD. The pathogenesis stages are complex and multifaceted, including factors such as lipid accumulation, inflammation, and plaque formation. A particular area of active exploration pertains to the influence and role of different biomarkers, including matrix metalloproteinase 9 (MMP-9) and myeloperoxidase (MPO), on these processes. These biomarkers have been associated with the progression and destabilization of athe-rosclerotic plaques, which are central to CAD. However, the use of these biomarkers in the context of comorbidities, such as chronic kidney disease, remains an open area of research, especially in patients after myocardial infarction. Materials and methods. In our study, 96 patients who had acute coronary syndrome and subsequently undergone percutaneous coronary intervention were enrolled. They were stratified into groups (A and B) based on respective glomerular filtration rates. The primary endpoint of the study was all-cause mortality and major adverse cardiovascular and cerebrovascular events. Results. Our analysis revealed that serum levels of MPO in group B were insignificantly higher than those in group A. Conversely, the area under the receiver operating characteristic (ROC) curve for MMP-9 in group A exhibited a significant difference, standing at 0.8 (95% confidence interval 0.609–0.991; p = 0.039). However, the ROC curve for MPO did not yield a significant result in any group. A combined ROC curve was also generated, with the area under this curve showing a significantly higher value of 0.890 (95% confidence interval 0.805–0.975; p < 0.001). Conclusions. We found that plasma levels of the above-mentioned biomarkers do not seem to influence a decrease in glomerular filtration rate. Nonetheless, MMP-9 levels offered significant prognostic information regarding predicted outcomes.
  • THE ROLE OF BIOCHEMICAL MARKERS AND PATIENT-REPORTED OUTCOMES IN PREDICTING COMPOSITE ONE-YEAR ENDPOINT IN ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION
    Iryna R. Vyshnevska, Olga V. Petyunina, Mykola P. Kopytsya, Anton O. Bilchenko, Larysa L. Peteneva
    Polski Merkuriusz Lekarski, 2023
  • The association of myeloperoxidase and SYNTAX score in patients with ST-elevation myocardial infarction
    Mykola Kopytsya, Iulia Rodionova, Nataliya Tytarenko, Inna Kutia, Yaroslava Hilova, Borys Shelest
    Gulhane Medical Journal, 2023
  • Matrix metallopeptidase-9 prognostic role in STEMI patients after percutaneous coronary intervention (PCI) in one-year follow-up period
    Mykola Kopytsya, Yaroslava Нilоva, Iulia Rodionova, Anton Bilchenko, Inna Kutia, Borys Shelest
    Cor Et Vasa, 2023
  • THE ROLE OF BIOMARKER MACROPHAGE MIGRATION INHIBITORY FACTOR IN CARDIAC REMODELING PREDICTION IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION
    Iryna R. Vyshnevska, Tatyana Storozhenko, Mykola P. Kopytsya, Natalia V. Bila, Andrii Kis, Mohammad Kaaki
    Wiadomosci Lekarskie Warsaw Poland 1960, 2023
  • Matrix metallopeptidase 9 and outcome prediction in patients with acute coronary syndrome
    A. O. Bilchenko, I. R. Vyshnevska, Ya. V. Hilova, M. P. Kopytsia
    Pathologia, 2022
  • Myeloperoxidase and global longitudinal strain in prognostication of clinical events after ST segment elevation myocardial infarction
    O. V. Petyunina, M. P. Kopytsya, A. V. Kobets, A. E. Berezin
    Ukrainian Therapeutical Journal, 2022
  • Practical use of the markers for prediction of adverse left ventricular remodeling after acute ST segment elevation myocardial infarction
    O. V. Petyunina, M. P. Kopytsya, I. R. Vyshnevska, T. Y. Storozhenko, A. V. Kobets
    Ukrainian Therapeutical Journal, 2022
  • A pre-specified analysis of the Dapagliflozin and Prevention of Adverse Outcomes in Chronic Kidney Disease (DAPA-CKD) randomized controlled trial on the incidence of abrupt declines in kidney function
    Hiddo J.L. Heerspink, David Cherney, Douwe Postmus, Bergur V. Stefánsson, Glenn M. Chertow, Jamie P. Dwyer, Tom Greene, Mikhail Kosiborod, Anna Maria Langkilde, John J.V. McMurray, Ricardo Correa-Rotter, Peter Rossing, C. David Sjöström, Robert D. Toto, David C. Wheeler, Hiddo J.L. Heerspink, David C. Wheeler, Glenn Chertow, Ricardo Correa-Rotter, Tom Greene, Fan Fan Hou, John McMurray, Peter Rossing, Robert Toto, Bergur Stefansson, Anna Maria Langkilde, L.E. Maffei, P. Raffaele, S.E. Solis, C.A. Arias, D. Aizenberg, C. Luquez, C. Zaidman, N. Cluigt, M. Mayer, A. Alvarisqueta, A. Wassermann, R. Maldonado, J. Bittar, M. Maurich, L.E. Gaite, N. Garcia, L. Sivak, P.O. Ramallo, J.C. Santos, R. Garcia Duran, J.A. Oddino, A. Maranon, L.N. Maia, D.D. Avila, E.J.G. Barros, M.H. Vidotti, D. Panarotto, I.D.L. Noronha, L.A.A. Turatti, L. Deboni, M.E. Canziani, M.C. Riella, M.R. Bacci, R.P. Paschoalin, R.J. Franco, J.C. Goldani, E. St-Amour, A.W. Steele, R. Goldenberg, S. Pandeya, H. Bajaj, D. Cherney, S.M. Kaiser, J.R. Conway, S.S. Chow, G. Bailey, J. Lafrance, J. Winterstein, S. Cournoyer, D. Gaudet, F. Madore, R.L. Houlden, A. Dowell, M. Langlois, N. Muirhead, H. Khandwala, A. Levin, F. Hou, Y. Xue, L. Zuo, C. Hao, Z. Ni, C. Xing, N. Chen, Y. Dong, R. Zhou, X. Xiao, Y. Zou, C. Wang, B. Liu, Q. Chen, M. Lin, Q. Luo, D. Zhang, J. Wang, M. Chen, X. Wang, A. Zhong, J. Dong, C. Zhu, T. Yan, P. Luo, Y. Ren, P. Pai, D. Li, R. Zhang, J. Zhang, M. Xu, Y. Zhuang, Y. Kong, X. Yao, X. Peng, F.I. Persson, T.K. Hansen, R. Borg, U. Pedersen Bjergaard, D. Hansen, M. Hornum, H. Haller, G. Klausmann, D. Tschope, T. Kruger, P. Gross, C. Hugo, N. Obermuller, L. Rose, P. Mertens, H. Zeller-Stefan, A. Fritsche, L. Renders, J. Muller, K. Budde, B. Schroppel, I. Wittmann, P. Voros, M. Dudas, G.A. Tabak, R. Kirschner, A. Letoha, I. Balku, Z. Hermanyi, G. Zakar, I. Mezei, G.G. Nagy, J. Lippai, A. Nemeth, D. Khullar, P.K. Gowdaiah, E. Fernando Mervin, V.A. Rao, D. Dewan, K. Goplani, V.S.K. Maddi, M.S. Vyawahare, R.K. Pulichikkat, R. Pandey, S.K. Sonkar, V.K. Gupta, S. Agarwal, A.J. Asirvatham, A. Ignatius, S. Chaubey, S. Melemadathil, H. Alva, Y. Kadam, H. Shimizu, A. Sueyoshi, H. Takeoka, Y. Abe, T. Imai, Y. Onishi, Y. Fujita, Y. Tokita, M. Oura, Y. Makita, A. Idogaki, R. Koyama, H. Kikuchi, N. Kashihara, T. Hayashi, Y. Ando, T. Tanaka, M. Shimizu, S. Hidaka, T. Gohda, K. Tamura, M. Abe, Y. Kamijo, T. Imasawa, Y. Takahashi, M. Nakayama, M. Tomita, F. Hirano, M. Nakayama, Y. Fukushima, A. Kiyosue, S. Kurioka, E. Imai, K. Kitagawa, M. Waki, J. Wada, K. Uehara, H. Iwatani, K. Ota, S. Shibazaki, K. Tamura, K. Katayama, I. Narita, M. Iinuma, S. Matsueda, S. Sasaki, A. Yokochi, T. Tsukamoto, T. Yoshimura, S. Kang, S. Lee, C.S. Lim, H. Chin, K.W. Joo, S.Y. Han, T.I. Chang, S. Park, H. Park, C.W. Park, B.G. Han, D.R. Cha, S.A. Yoon, W. Kim, S.W. Kim, D. Ryu, R. Correa Rotter, S.S. Irizar Santana, G. Hernandez Llamas, R. Valdez Ortiz, N.C. Secchi Nicolas, G. Gonzalez Galvez, J.R. Lazcano Soto, T. Bochicchio Riccardelli, E.A. Bayram Llamas, D.R. Ramos Ibarra, M.G.S. Melo, J.G. Gonzalez Gonzalez, J.H. Sanchez Mijangos, M. Madero Robalo, A. Garcia Castillo, H.A. Manrique, J.C. Farfan, R. Vargas, A. Valdivia, A. Dextre, E. Escudero, J.R. Calderon Ticona, L. Gonzales, J. Villena, L. Leon, G. Molina, A. Saavedra, E. Garrido, H. Arbanil, S. Vargas Marquez, J. Rodriguez, R. Isidto, A.J. Villaflor, M.A. Gumba, L. Tirador, R.S. Comia, R.A. Sy, M.L.V.V. Guanzon, G. Aquitania, N.C. De Asis, A.A. Silva, C.M. Romero, M.E. Lim, R.A. Danguilan, M. Nowicki, H. Rudzki, K. Landa, I. Kucharczyk-Bauman, B. Gogola-Migdal, M. Golski, A. Olech-Cudzik, T. Stompor, T. Szczepanik, B. Miklaszewicz, R. Sciborski, M. Kuzniewski, K. Ciechanowski, D. Wronska, W. Klatko, S. Mazur, G. Popenda, M. Myslicki, L.Z. Bolieva, S. Berns, A. Galyavich, T. Abissova, I. Karpova, D. Platonov, N. Koziolova, L. Kvitkova, R. Nilk, T. Medina, A. Rebrov, M. Rossovskaya, I. Sinitsina, E. Vishneva, N. Zagidullin, T. Novikova, N. Krasnopeeva, O. Magnitskaya, N. Antropenko, M. Batiushin, V. Escudero Quesada, C. Barrios Barrea, E. Espinel Garauz, J.M. Cruzado Garrit, C. Morales Portillo, J.L. Gorriz Teruel, S. Cigarran Guldris, M. Praga Terente, N.R. Robles Perez-Monteoliva, F.J. Tinahones Madueno, A. Soto Gonzalez, C. Diaz Rodriguez, H. Furuland, A. Saeed, K. Dreja, J. Spaak, A. Bruchfeld, M. Kolesnyk, O. Levchenko, N. Pyvovarova, V. Stus, V. Doretskyy, N. Korobova, O. Horoshko, I. Katerenchuk, Y.M. Mostovoy, M. Orynchak, O. Legun, I. Dudar, O. Bilchenko, S. Andreychyn, A. Levchenko, L. Zub, N. Tereshchenko, I. Topchii, T. Ostapenko, S. Bezuglova, M. Kopytsya, O. Turenko, P. Mark, J. Barratt, S. Bhandari, D. Fraser, P. Kalra, S.P. Kon, K. Mccafferty, A. Mikhail, S.P. Kon, O.P. Alvarado, R. Anderson, N.S. Andrawis, A. Arif, S.A. Benjamin, G. Bueso, R.S. Busch, K.W. Carr, P. Crawford, N. Daboul, G.M. De La Calle, B. Delgado, J. Earl, M.A. El-Shahawy, R.J. Graf, G. Greenwood, A. Guevara, E.M. Wendland, R.K. Mayfield, M. Montero, D.J. Morin, P. Narayan, V. Numrungroad, A.C. Reddy, R. Reddy, M.B. Samson, R. Trejo, M.B. Butcher, J.K. Wise, L.R. Zemel, M. Raikhel, D. Weinstein, P. Hernandez, A. Wynne, B.V. Khan, G.A. Sterba, A. Jamal, D. Ross, S.F. Rovner, A. Tan, F. Ovalle, R.J. Patel, J. Talano, D.R. Patel, A. Burgner, N. Aslam, M. Elliott, S. Goral, A. Jovanovich, J.A. Manley, K. Umanath, D. Waguespack, D. Weiner, M. Yu, L. Schneider, D. Jalal, T. Le, N. Nguyen, H. Nguyen, D. Nguyen, V. Nguyen, T. Do, P. Chu, D. Ta, N. Tran, D. Nguyen, B. Pham, Marc A. Pfeffer, Stuart Pocock, Karl Swedberg, Jean L. Rouleau, Nishi Chaturvedi, Peter Ivanovich, Andrew S. Levey, Heidi Christ-Schmidt, Claes Held, Christina Christersson, Johannes Mann, Christoph Varenhorst
    Kidney International, 2022
  • Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol
    Gregory G. Schwartz, Michael Szarek, Vera A. Bittner, Rafael Diaz, Shaun G. Goodman, J. Wouter Jukema, Ulf Landmesser, Patricio López-Jaramillo, Garen Manvelian, Robert Pordy, Michel Scemama, Peter R. Sinnaeve, Harvey D. White, Ph Gabriel Steg, Gregory G. Schwartz, P.h. Gabriel Steg, Deepak L. Bhatt, Vera A. Bittner, Rafael Diaz, Shaun G. Goodman, Robert A. Harrington, J. Wouter Jukema, Michael Szarek, Harvey D. White, Andreas M. Zeiher, Pierluigi Tricoci, Matthew T. Roe, Kenneth W. Mahaffey, Jay M. Edelberg, Corinne Hanotin, Guillaume Lecorps, Angèle Moryusef, Robert Pordy, William J. Sasiela, Jean-François Tamby, Rafael Diaz, Philip E. Aylward, Heinz Drexel, Peter Sinnaeve, Mirza Dilic, Renato D. Lopes, Nina N. Gotcheva, Shaun G. Goodman, Juan-Carlos Prieto, Huo Yong, Patricio López-Jaramillo, Ivan Pećin, Zeljko Reiner, Petr Ostadal, Steen Hvitfeldt Poulsen, Margus Viigimaa, Markku S. Nieminen, Nicolas Danchin, Vakhtang Chumburidze, Nikolaus Marx, Evangelos Liberopoulos, Pablo Carlos Montenegro Valdovinos, Hung-Fat Tse, Robert Gabor Kiss, Denis Xavier, Doron Zahger, Marco Valgimigli, Takeshi Kimura, Hyo Soo Kim, Sang-Hyun Kim, Andrejs Erglis, Aleksandras Laucevicius, Sasko Kedev, Khalid Yusoff, Gabriel Arturo Ramos López, Marco Alings, Harvey D. White, Sigrun Halvorsen, Roger M. Correa Flores, Rody G. Sy, Andrzej Budaj, Joao Morais, Maria Dorobantu, Yuri Karpov, Arsen D. Ristic, Terrance Chua, Jan Murin, Zlatko Fras, Anthony J. Dalby, José Tuñón, H. Asita de Silva, Emil Hagström, Ulf Landmesser, Christian Müller, Chern-En Chiang, Piyamitr Sritara, Sema Guneri, Alexander Parkhomenko, Kausik K. Ray, Patrick M. Moriarty, Matthew T. Roe, Robert Vogel, Bernard Chaitman, Sheryl F. Kelsey, Anders G. Olsson, Jean-Lucien Rouleau, Maarten L. Simoons, Karen Alexander, Chiara Meloni, Robert Rosenson, Eric J.G. Sijbrands, Pierluigi Tricoci, John H. Alexander, Luciana Armaganijan, Akshay Bagai, Maria Cecilia Bahit, J. Matthew Brennan, Shaun Clifton, Adam D. DeVore, Shalonda Deloatch, Sheila Dickey, Keith Dombrowski, Grégory Ducrocq, Zubin Eapen, Patricia Endsley, Arleen Eppinger, Robert W. Harrison, Connie Ng Hess, Mark A. Hlatky, Joseph Dedrick Jordan, Joshua W. Knowles, Bradley J. Kolls, David F. Kong, Sergio Leonardi, Linda Lillis, Renato D. Lopes, David J. Maron, Kenneth W. Mahaffey, Jill Marcus, Robin Mathews, Rajendra H. Mehta, Robert J. Mentz, Humberto Graner Moreira, Chetan B. Patel, Sabrina Bernardez Pereira, Lynn Perkins, Thomas J. Povsic, Etienne Puymirat, Matthew T. Roe, William Schuyler Jones, Bimal R. Shah, Matthew W. Sherwood, Kenya Stringfellow, Darin Sujjavanich, Mustafa Toma, Charlene Trotter, Sean F.P. van Diepen, Matthew D. Wilson, Andrew Tze-Kay Yan, Lilia B. Schiavi, Marcelo Garrido, Andrés F. Alvarisqueta, Sonia A. Sassone, Anselmo P. Bordonava, Alberto E. Alves De Lima, Jorge M. Schmidberg, Ernesto A. Duronto, Orlando C. Caruso, Leonardo P. Novaretto, Miguel Angel Hominal, Oscar R. Montaña, Alberto Caccavo, Oscar A. Gomez Vilamajo, Alberto J. Lorenzatti, Luis R. Cartasegna, Gustavo A. Paterlini, Ignacio J. Mackinnon, Guillermo D. Caime, Marcos Amuchastegui, Oscar Salomone, Oscar R. Codutti, Horacio O. Jure, Julio O.E. Bono, Adrian D. Hrabar, Julio A. Vallejos, Rodolfo A. Ahuad Guerrero, Federico Novoa, Cristian A. Patocchi, Cesar J. Zaidman, Maria E. Giuliano, Ricardo D. Dran, Marisa L. Vico, Gabriela S. Carnero, Pablo N. Guzman, Juan C. Medrano Allende, Daniela F. Garcia Brasca, Miguel H. Bustamante Labarta, Sebastian Nani, Eduardo D.S. Blumberg, Hugo R. Colombo, Alberto Liberman, Victorino Fuentealba, Hector L. Luciardi, Gabriel D. Waisman, Mario A. Berli, Ruben O. Garcia Duran, Horacio G. Cestari, Hugo A. Luquez, Jorge A. Giordano, Silvia S. Saavedra, Gerardo Zapata, Osvaldo Costamagna, Susana Llois, Jonathon H. Waites, Nicholas Collins, Allan Soward, Philip E. Aylward, Chris L.S. Hii, Philip E. Aylward, James Shaw, Margaret A. Arstall, John Horowitz, Daniel Ninio, James F. Rogers, David Colquhoun, Romulo E. Oqueli Flores, Philip Roberts-Thomson, Owen Raffel, Sam J. Lehman, Constantine Aroney, Steven G.M. Coverdale, Paul J. Garrahy, Gregory Starmer, Mark Sader, Patrick A. Carroll, Ronald Dick, Robert Zweiker, Uta Hoppe, Heinz Drexel, Kurt Huber, Rudolf Berger, Georg Delle-Karth, Bernhard Frey, Dirk Faes, Kurt Hermans, Bruno Pirenne, Attilio Leone, Etienne Hoffer, Peter Sinnaeve, Mathias C.M. Vrolix, Luc De Wolf, Bart Wollaert, Marc Castadot, Karl Dujardin, Christophe Beauloye, Geert Vervoort, Harry Striekwold, Carl Convens, John Roosen, Emanuele Barbato, Marc Claeys, Frank Cools, Ibrahim Terzic, Fahir Barakovic, Zlatko Midzic, Belma Pojskic, Emir Fazlibegovic, Mirza Dilic, Azra Durak-Nalbantic, Mehmed Kulić, Dusko Vulic, Adis Muslibegovic, Boris Goronja, Gilmar Reis, Luciano Sousa, Jose C. Nicolau, Flavio E. Giorgeto, Ricardo P. Silva, Lilia Nigro Maia, Rafael Rech, Paulo R.F. Rossi, Maria José A.G. Cerqueira, Norberto Duda, Renato Kalil, Adrian Kormann, José Antonio M. Abrantes, Pedro Pimentel Filho, Ana Priscila Soggia, Mayler O.N. de Santos, Fernando Neuenschwander, Luiz C. Bodanese, Yorghos L. Michalaros, Freddy G. Eliaschewitz, Maria H. Vidotti, Paulo E. Leaes, Roberto V. Botelho, Sergio Kaiser, Euler Roberto F. Fernandes Manenti, Dalton B. Precoma, Jose C. Moura Jorge, Pedro Silva, Jose A. Silveira, Wladmir Saporito, Jose A. Marin Neto, Gilson S. Feitosa, Luiz Eduardo F. Ritt, Juliana A. de Souza, Fernando Costa, Weimar K.S.B. Souza, Helder J.L. Reis, Renato D. Lopes, Leandro Machado, José Carlos Aidar Ayoub, Georgi V. Todorov, Fedya P. Nikolov, Elena S. Velcheva, Maria L. Tzekova, Haralambi O. Benov, Stanislav L. Petranov, Haralin S. Tumbev, Nina S. Shehova-Yankova, Dimitar T. Markov, Dimitar H. Raev, Mihail N. Mollov, Kostadin N. Kichukov, Katya A. Ilieva-Pandeva, Nina N. Gotcheva, Raya Ivanova, Maryana Gospodinov, Valentina M. Mincheva, Petar V. Lazov, Bojidar I. Dimov, Manohara Senaratne, James Stone, Jan Kornder, Stephen Pearce, Danielle Dion, Daniel Savard, Yves Pesant, Amritanshu Pandey, Simon Robinson, Gilbert Gosselin, Saul Vizel, Gordon Hoag, Ronald Bourgeois, Anne Morisset, Eric Sabbah, Bruce Sussex, Simon Kouz, Paul MacDonald, Ariel Diaz, Nicolas Michaud, David Fell, Raymond Leung, Tycho Vuurmans, Christopher Lai, Frank Nigro, Richard Davies, Gustavo Nogareda, Ram Vijayaraghavan, John Ducas, Serge Lepage, Shamir Mehta, James Cha, Robert Dupuis, Peter Fong, Sohrab Lutchmedial, Josep Rodes-Cabau, Hussein Fadlallah, David Cleveland, Thao Huynh, Iqbal Bata, Adnan Hameed, Cristian Pincetti, Sergio Potthoff, Juan C. Prieto, Monica Acevedo, Arnoldo Aguirre, Margarita Vejar, Mario Yañez, Guillermo Araneda, Mauricio Fernandez, Luis Perez, Paola Varleta, Fernando Florenzano, Laura Huidobro, Carlos A. Raffo, Claudia Olivares, Leonardo Nahuelpan, Humberto Montecinos, Jiyan Chen, Yugang Dong, Weijian Huang, Jianzhong Wang, Shi'An Huang, Zhuhua Yao, Xiang Li, Lan Cui, Wenhua Lin, Yuemin Sun, Jingfeng Wang, Jianping Li, Xuelian Zhang, Hong Zhu, Dandan Chen, Lan Huang, Shaohong Dong, Guohai Su, Biao Xu, Xi Su, Xiaoshu Cheng, Jinxiu Lin, Wenxia Zong, Huanming Li, Yi Feng, Dingli Xu, Xinchun Yang, Yuannan Ke, Xuefeng Lin, Zheng Zhang, Zeqi Zheng, Zhurong Luo, Yundai Chen, Chunhua Ding, Yi Zhong, Yang Zheng, Xiaodong Li, Daoquan Peng, Shuiping Zhao, Ying Li, Xuebo Liu, Meng Wei, Shaowen Liu, Yihua Yu, Baiming Qu, Weihong Jiang, Yujie Zhou, Xingsheng Zhao, Zuyi Yuan, Ying Guo, Xiping Xu, Xubo Shi, Junbo Ge, Guosheng Fu, Feng Bai, Weiyi Fang, Xiling Shou, Xiangjun Yang, Jian'An Wang, Meixiang Xiang, Yingxian Sun, Qinghua Lu, Ruiyan Zhang, Jianhua Zhu, Yizhou Xu, Zhongcai Fan, Tianchang Li, Chun Wu, Nicolas Jaramillo, Gregorio Sanchez Vallejo, Diana C. Luna Botia, Rodrigo Botero Lopez, Dora I. Molina De Salazar, Alberto J. Cadena Bonfanti, Carlos Cotes Aroca, Juan Diego Higuera, Marco Blanquicett, Sandra I. Barrera Silva, Henry J. Garcia Lozada, Julian A. Coronel Arroyo, Jose L. Accini Mendoza, Ricardo L. Fernandez Ruiz, Alvaro M. Quintero Ossa, Fernando G. Manzur Jatin, Aristides Sotomayor Herazo, Jeffrey Castellanos Parada, Rafael Suarez Arambula, Miguel A. Urina Triana, Angela M. Fernandez Trujillo, Maja Strozzi, Siniša Car, Melita Jerić, Davor Miličić, Martina Lovrić Benčić, Hrvoje Pintarić, Đeiti Prvulović, Jozica Šikić, Viktor Peršić, Dean Mileta, Kresimir Štambuk, Zdravko Babić, Vjekoslav Tomulic, Josip Lukenda, Stanka Mejic-Krstulovic, Boris Starcevic, Jindrich Spinar, David Horak, Zdenek Velicka, Josef Stasek, David Alan, Vilma Machova, Ales Linhart, Vojtech Novotny, Vladimir Kaucak, Richard Rokyta, Robert Naplava, Zdenek Coufal, Vera Adamkova, Ivo Podpera, Jiri Zizka, Zuzana Motovska, Ivana Marusincova, Premysl Svab, Petr Ostadal, Petr Heinc, Jiri Kuchar, Petr Povolny, Jiri Matuska, Steen H. Poulsen, Bent Raungaard, Peter Clemmensen, Lia E. Bang, Ole May, Morten Bøttcher, Jens D. Hove, Lars Frost, Gunnar Gislason, John Larsen, Peter Betton Johansen, Flemming Hald, Peter Johansen, Jørgen Jeppesen, Tonny Nielsen, Kjeld S. Kristensen, Piotr Maria Walichiewicz, Jens D. Lomholdt, Ib C. Klausen, Peter Kaiser Nielsen, Flemming Davidsen, Lars Videbaek, Margus Viigimaa, Mai Soots, Veiko Vahula, Anu Hedman, Üllar Soopõld, Kaja Märtsin, Tiina Jurgenson, Arved Kristjan, Markku S. Nieminen, Heikki Huikuri, Juhani Airaksinen Pierre Coste, Emile Ferrari, Nicolas Danchin, Olivier Morel, Gilles Montalescot, Jacques Machecourt, Gilles Barone-Rochette, Jacques Mansourati, Yves Cottin, P.h. Gabriel Steg, Florence Leclercq, Abdelkader Belhassane, Nicolas Delarche, Franck Boccara, Franck Paganelli, Jérôme Clerc, Francois Schiele, Victor Aboyans, Vincent Probst, Jacques Berland, Thierry Lefèvre, Bernard Citron, Vakhtang Chumburidze, Irakli Khintibidze, Tamaz Shaburishvili, Zurab Pagava, Ramaz Ghlonti, Zaza Lominadze, George Khabeishvili, Rayyan Hemetsberger, Kemala Edward, Ursula Rauch-Kröhnert, Matthias Stratmann, Karl-Friedrich Appel, Ekkehard Schmidt, Heyder Omran, Christoph Stellbrink, Thomas Dorsel, Emmanouil Lianopoulos, Hans Friedrich Vöhringer, Roger Marx, Andreas Zirlik, Detlev Schellenberg, Thomas Heitzer, Ulrich Laufs, Christian Werner, Nikolaus Marx, Stephan Gielen, Sebastian Nuding, Bernhard Winkelmann, Steffen Behrens, Karsten Sydow, Mahir Karakas, Gregor Simonis, Thomas Muenzel, Nikos Werner, Stefan Leggewie, Dirk Böcker, Rüdiger Braun-Dullaeus, Nicole Toursarkissian, Michael Jeserich, Matthias Weißbrodt, Tim Schaeufele, Joachim Weil, Heinz Völler, Johannes Waltenberger, Mohammed Natour, Susanne Schmitt, Dirk Müller-Wieland, Stephan Steiner, Lothar Heidenreich, Elmar Offers, Uwe Gremmler, Holger Killat, Werner Rieker, Sotiris Patsilinakos, Athanasios Kartalis, Athanassios Manolis, Dimitrios Sionis, Geargios Chachalis, Evangelos Liberopoulos, Ioannis Skoumas, Vasilios Athyros, Panagiotis Vardas, Frangkiskos Parthenakis, John Lekakis, Apostolos Hatzitolios, Sergio R. Fausto Ovando, Pablo Carlos Montenegro Valdovinos, Juan L. Arango Benecke, Edgar R. Rodriguez De Leon, Bryan P.Y. Yan, David C.W. Siu, Tibor Turi, Bela Merkely, Robert Gabor Kiss, Imre Ungi, Geza Lupkovics, Lajos Nagy, András Katona, István Édes, Gábor Müller, Iván Horvath, Tibor Kapin, Zsolt Szigeti, József Faluközy, Mukund Kumbla, Manjinder Sandhu, Sharath Annam, Naveen Reddy Proddutur, Reddy Regella, Rajendra K. Premchand, Ajaykumar Mahajan, Sudhir Pawar, Atul D. Abhyanakar, Prafulla Kerkar, Ravishankar A. Govinda, Abraham Oomman, Dhurjati Sinha, Sachin N. Patil, Dhiman Kahali, Jitendra Sawhney, Abhijeet B. Joshi, Sanjeev Chaudhary, Pankaj Harkut, Santanu Guha, Sanjay Porwal, Srimannarayana Jujjuru, Ramesh B. Pothineni, Minguel R. Monteiro, Aziz Khan, Shamanna S. Iyengar, Jasprakash Singh Grewal, Manoj Chopda, Mahesh C. Fulwani, Aparna Patange, Patil Sachin, Vijay K. Chopra, Naresh K. Goyal, Rituparna Shinde, Gajendra V. Manakshe, Nitin Patki, Sumeet Sethi, Vengatesh Munusamy, Sunil Karnaand Sunil Thanvi, Srilakshmi Adhyapak, Chandrakant Patil, Ulhas Pandurangi, Rishabh Mathur, Jugal Gupta, Suhas Kalashetti, Ajit Bhagwat, Bagirath Raghuraman, Shiv Kumar Yerra, Prasant Bhansali, Rohidas Borse, Patil Rahul, Srihari Das, Vinay Kumar, Jabir Abdullakutty, Shireesh Saathe, Priya Palimkar, Jabir Abdullkutty, Shireesh Sathe, Shaul Atar, Michael Shechter, Morris Mosseri, Yaron Arbel, Chorin Ehud, Havakuk Ofer, Chaim Lotan, Uri Rosenschein, Amos Katz, Yaakov Henkin, Adi Francis, Marc Klutstein, Eugenia Nikolsky, Robert Zukermann, Yoav Turgeman, Majdi Halabi, Alon Marmor, Ran Kornowski, Michael Jonas, Offer Amir, Yonathan Hasin, Yoseph Rozenman, Shmuel Fuchs, Vered Zvi, Osamah Hussein, Dov Gavish, Zvi Vered, Yoseph Caraco, Mazen Elias, Naveh Tov, Efrat Wolfovitz, Michael Lishner, Nizar Elias, Giancarlo Piovaccari, Annamaria De Pellegrin, Raffaella Garbelotto, Gabriele Guardigli, Valgimigli Marco, Giovanni Licciardello, Carla Auguadro, Filippo Scalise, Claudio Cuccia, Alessandro Salvioni, Giuseppe Musumeci, Michelle Senni, Paolo Calabrò, Salvatore Novo, Pompilio Faggiano, Marco Metra, Nicoletta B. De Cesare, Sergio Berti, Claudio Cavallini, Enrico Puccioni, Marcello Galvani, Maurizio Tespili, Piermarco Piatti, Michela Palvarini, Giuseppe De Luca, Roberto Violini, Alessandro De Leo, Zoran Olivari, Pasquale Perrone Filardi, Maurizio Ferratini, Vittorio Racca, Kazuoki Dai, Yuji Shimatani, Haruo Kamiya, Kenji Ando, Yoshihiro Takeda, Yoshihiro Morino, Yoshiki Hata, Kazuo Kimura, Koichi Kishi, Ichiro Michishita, Hiroki Uehara, Toshinori Higashikata, Atsushi Hirayama, Keiji Hirooka, Yasuji Doi, Satoru Sakagami, Shuichi Taguchi, Akihiro Koike, Hiroyuki Fujinaga, Shinji Koba, Ken Kozuma, Tomohiro Kawasaki, Yujiro Ono, Masatoshi Shimizu, Yousuke Katsuda, Atsuyuki Wada, Toshiro Shinke, Takeshi Kimura, Junya Ako, Kenshi Fujii, Toshiyuki Takahashi, Tomohiro Sakamoto, Koichi Nakao, Yutaka Furukawa, Hiroshi Sugino, Ritsu Tamura, Toshiaki Mano, Masaaki Uematsu, Noriaki Utsu, Kashima Ito, Takuya Haraguchi, Katsuhiko Sato, Yasunori Ueda, Akira Nishibe, Kazuteru Fujimoto, Motomaru Masutani, Akira Nishibe, Kazuteru Fujimoto, Jung Han Yoon, Sang-Hyun Kim, Hack-Lyoung Kim, Hun Sik Park, In-Ho Chae, Moo Hyun Kim, Myung Ho Jeong, Seungwoon Rha, Chongjin Kim, Hae Young Kim, Taekjong Hong, Seung-Jea Tahk, Youngkwon Kim, Arija Busmane, Natalija Pontaga, Aldis Strelnieks, Iveta Mintale, Iveta Sime, Zaneta Petrulioniene, Roma Kavaliauskiene, Ruta Jurgaitiene, Gintare Sakalyte, Rimvydas Slapikas, Sigute Norkiene, Nerijus Misonis, Aleksandras Kibarskis, Raimondas Kubilius, Stojko Bojovski, Sasko Kedev, Nensi Lozance, Aleksandar Kjovkaroski, Snezana Doncovska, Tiong Kiam Ong, Sazzli Kasim, Oteh Maskon, Balachandran Kandasamy, Khalid Yusoff, Houng B. Liew, Wan Mohd Izani Wan Mohamed, Armando García Castillo, Jorge Carrillo Calvillo, Pedro Fajardo Campos, Juan Carlos Núñez Fragoso, Edmundo Alfredo Bayram Llamas, Marco Antonio Alcocer Gamba, Jaime Carranza Madrigal, Luis Gerardo González Salas, Enrique López Rosas, Belinda González Díaz, Eduardo Salcido Vázquez, Alfredo Nacoud Ackar, Guillermo Antonio Llamas Esperón, Carlos Rodolfo Martínez Sánchez, María Guerrero De Leon, Rodrigo Suarez Otero, Guillermo Fanghänel Salmón, Jesús Antonio Pérez Ríos, José Angel Garza Ruíz, Marco Alings, Robert W. Breedveld, Margriet Feenema-Aardema, Alida Borger-Van Der Burg, Pieter A.M. Hoogslag, Harry Suryapranata, Antonius Oomen, Paulus Van Haelst, Margriet Feenema-Aradema, Jacobijne J. Wiersma, Dirk Basart, Ruud M.A. Van Der Wal, Peter Zwart, Pascalle Monraats, Henricus Van Kesteren, Ioannis Karalis, Johan Jukema, Gerardus J.E. Verdel, Bart R.G. Brueren, Roland PTh Troquay, Eric P. Viergever, Nadea Y.Y. Al-Windy, Gerard L. Bartels, Jan H. Cornel, Walter R.M. Hermans, Johannes P.R. Herrman, Robert J. Bos, Reginald G.E.J. Groutars, Coenraad C. Van Der Zwaan, Refik Kaplan, Raymond Lionarons, Eelko Ronner, Bjorn E. Groenemeijer, Patrick N.A. Bronzwaer, Anho A.H. Liem, Bernard J.W.M. Rensing, Marcel J.J.A. Bokern, Remco Nijmeijer, Ferry M.R.J. Hersbach, Frank F. Willems, Antonius T.M. Gosselink, Saman Rasoul, John Elliott, Gerard Wilkins, Raewyn Fisher, Douglas Scott, Hamish Hart, Ralph Stewart, Scott Harding, Ian Ternouth, Nicholas Fisher, Samuel Wilson, Denise Aitken, Russell Anscombe, Laura Davidson, Tadeusz Tomala, Ottar Nygård, Jon Arne Sparby, Kjell Andersen, Lars Gullestad, Jarle Jortveit, Peter S. Munk, Erlend gyllensten Singsaas, Sigrun Halvorsen, Ulf Hurtig, Roger M. Correa Flores, Jorge R. Calderon Ticona, Julio R. Durand Velasquez, Sandra A. Negron Miguel, Enrique S. Sanabria Perez, Jesus M. Carrion Chambilla, Carlos A. Chavez Ayala, Reynaldo P. Castillo Leon, Rolando J. Vargas Gonzales, Jose D. Hernandez Zuniga, Luis A. Camacho Cosavalente, Jorge E. Bravo Mannucci, Javier Heredia Landeo, Nassip C. Llerena Navarro, Yudy M. Roldan Concha, Víctor E. Rodriguez Chavez, Henry A. Anchante Hernandez, Carlos A. Zea Nunez, Walter Mogrovejo Ramos, Arthur Ferrolino, Rosa Allyn G. Sy, Louie Tirador, Rody G. Sy, Generoso Matiga, Raul Martin Coching, Alisa Bernan, Gregorio Rogelio, Dante D. Morales, Edgar Tan, Dennis Jose Sulit, Adrian Wlodarczak, Krystyna Jaworska, Grzegorz Skonieczny, Lidia Pawlowicz, Pawel Wojewoda, Benita Busz-Papiez, Janusz Bednarski, Aleksander Goch, Pawel Staneta, Elzbieta Dulak, Andrzej Budaj, Krzysztof Saminski, Wlodzimierz Krasowski, Wanda Sudnik, Aleksander Zurakowski, Marcin Skorski, Roman Lysek, Beata Miklaszewicz, Jacek Kubica, Jan Andrzej Lipko, Edyta Kostarska-Srokosz, Marek Piepiorka, Anna Drzewiecka, Ryszard Sciborski, Arkadiusz Stasiewski, Tomasz Blicharski, Leszek Bystryk, Michal Szpajer, Marek Korol, Tomasz Czerski, Ewa Mirek-Bryniarska, Jacek Gniot, Andrzej Lubinski, Jerzy Gorny, Edward Franek, Grzegorz Raczak, Hanna Szwed, Pedro Monteiro, Jose Mesquita Bastos, Helder H. Pereira, Dinis Martins, Joao Morais, Filipe Seixo, Carlos Mendonça, Ana Botelho, Francisca Caetano, Bogdan Minescu, Octavian Istratoaie, Dan N. Tesloianu, Maria Dorobantu, Gabriel Cristian, Silviu Dumitrescu, Cristian G.C. Podoleanu, Mircea C.A. Constantinescu, Cristina M. Bengus, Constantin Militaru, Doina Rosu, Irinel R. Parepa, Adrian V. Matei, Tom M. Alexandru, Mihaela Malis, Ioan Coman, Rodica Stanescu-Cioranu, Doina Dimulescu, Yury Shvarts, Olga Orlikova, Zhanna Kobalava, Olga L. Barbarash, Valentin Markov, Nadezhda Lyamina, Alexander Gordienko, Konstantin Zrazhevsky, Alexander Y. Vishnevsky, Victor Gurevich, Raisa Stryuk, Nikita V. Lomakin, Igor Bokarev, Tatiana Khlevchuk, Sergey Shalaev, Larisa Khaisheva, Petr Chizhov, Inna Viktorova, Natalya Osokina, Vladimir Shchekotov, Evgenia Akatova, Galina Chumakova, Igor Libov, Mikhail I. Voevoda, Tatyana V. Tretyakova, Evgeny Baranov, Sergey Shustov, Sergey Yakushin, Ivan Gordeev, Niiaz Khasanov, Olga Reshetko, Tatiana Sotnikova, Olga Molchanova, Konstantin Nikolaev, Liudmila Gapon, Elena Baranova, Zaur Shogenov, Elena Kosmachova, Yuriy Karpov, Yuri Karpov, Anton Povzun, Liudmila Egorova, Vadim V. Tyrenko, Igor G. Ivanov, Masterov Ilya, Sergey Kanorsky, Dragan Simic, Nikola Ivanovic, Goran Davidovic, Nebojsa Tasic, Milika R. Asanin, Stevo Stojic, Svetlana R. Apostolovic, Stevan Ilic, Biljana Putnikovic Tosic, Aleksandar Stankovic, Aleksandra Arandjelovic, Slavica Radovanovic, Branislava Todic, Arsen D. Ristic, Jovan Balinovac, Dragan V. Dincic, Petar Seferovic, Ana Karadzic, Slobodan Dodic, Sinisa Dimkovic, Tamara Jakimov, Terrance Chua, Kian-Keong Poh, Hean Yee Ong, Justin Tang I-Shing, Karol Micko, Jan Nociar, Daniel Pella, Peter Fulop, Marian Hranai, Juraj Palka, Juraj Mazur, Ivan Majercák, Andrej Dzupina, František Fazekas, Jozef Gonsorcik, Viliam Bugan, Jan Murin, Juraj Selecky, Gabriel Kamensky, Jaroslava Strbova, Rudolf Smik, Andrej Dukat, Peter Olexa, Ivan Žuran, Janez Poklukar, Nataša Černič Šuligoj, Matija Cevc, Zlatko Fras, Henry P. Cyster, Naresh Ranjith, Clive Corbett, Junaid Bayat, Ellen Makoali Makotoko, Hendrik du Toit Theron, Ilse E. 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  • Soluble st2 in predicting adverse outcome after revascularization with percutaneous coronary intervention in patients with st-elevation myocardial infarction
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  • Universal definition of myocardial infarction
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  • The effectiveness of the differentiated approach to the choice of double antiplatelet therapeutic depending on the G634C polymorphism of the VEGF-A gene in acute myocardial infarction with ST segment elevation
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  • Single nuclear polymorphism Val66Met (rs6265) of brain derived neurotrophic factor gene in prognostication of outcomes after ST segment elevation myocardial infarction
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    Ukrainian Journal of Cardiology, 2020
  • Subclinical emotional distress predicts 6-month clinical outcomes after ST-segment elevation myocardial infarction
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    Future Cardiology, 2020
  • Brain-derived neurotrophic factor gene polymorphism in post-ST-elevation myocardial infarction patients undergoing primary percutaneous intervention
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    Biomedical Research and Therapy, 2020
  • Brain derived neurotrophic factor and its polymorphism Val66Met (rs6265). Significance for cardiovascular system
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  • The predictive value ofvascular endothelial growth factor-A genepolymorphism for clinical outcomes among acute ST-segmentelevation myocardial infarction patients: A single centerprospective study
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  • BIOMARKER sST2ASAN EARLY PREDICTOR OFACUTE RENAL INJURY IN PATIENTS WITH ST-SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION
    Georgian Medical News, 2020
  • The utility of new biomarker-based predictive model for clinical outcomes among st-elevation myocardial infarction patients
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    Open Biomarkers Journal, 2020
  • The role of growth differentiation factor 15 as a predictor of 5-year survival of patients after acute coronary syndrome
    Polski Merkuriusz Lekarski, 2020
  • The effect of beta-blockers on a course of chronic heart failure in patients with a low triiodothyronine syndrome
    Wiadomosci Lekarskie Warsaw Poland 1960, 2020
  • Adrenal metastases of renal cell carcinoma with intravenous tumor thrombi of the inferior vena cava (two case reports with literature review)
    D. V. Shchukin, V. N. Lesovoy, U. M. Balarabe, G. G. Khareba, I. M. Antonian, M. P. Kopytsya, A. I. Harahatyi, A. V. Shus
    Problemi Endokrinnoi Patologii, 2020
  • Removal of the Tumor Thrombus from the Right Atrium without Extracorporeal Circulation: Emphasis on the Displacement of the Tumor Apex
    D. V. Shchukin, V. N. Lesovoy, G. G. Khareba, A. I. Harahatyi, A. V. Maltsev, M. M. Polyakov, R. V. Stetsyshyn, M. P. Kopytsya, P. V. Mozzhakov, O. O. Makovozov
    Advances in Urology, 2020
  • NEPHRON-SPARING SURGERY IN PATIENTS WITH RENAL CELL CARCINOMA EXTENDING TO THE MAIN RENAL VEIN: INTRARENAL AND EXTRARENAL THROMBECTOMY
    Georgian Medical News, 2019
  • The association of polymorphisms of β-adrenergic receptors genes with the low triiodothyronine syndrome in patients with a heart failure
    Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2019
  • Associations between macrophage inhibitor factor, anxiety and depression in patients with ST-segment elevation myocardial infarction
    O. V. Petyunina, M. P. Kopytsya, О. V. Skrynnik
    Ukrainian Journal of Cardiology, 2019
  • The role of Val66Met single nucleotide polymorphism in brain-derived neurotropic factor gene in prediction of adverse outcomes after ST-segment elevation myocardial infarction
    Olga V. Petyunina, Mykola P. Kopytsya, Alexander E. Berezin, Olga V. Skrynnyk
    Heart and Mind, 2019
  • Alirocumab and cardiovascular outcomes after acute coronary syndrome
    Gregory G. Schwartz, P. Gabriel Steg, Michael Szarek, Deepak L. Bhatt, Vera A. Bittner, Rafael Diaz, Jay M. Edelberg, Shaun G. Goodman, Corinne Hanotin, Robert A. Harrington, J. Wouter Jukema, Guillaume Lecorps, Kenneth W. Mahaffey, Angèle Moryusef, Robert Pordy, Kirby Quintero, Matthew T. Roe, William J. Sasiela, Jean-François Tamby, Pierluigi Tricoci, Harvey D. White, Andreas M. Zeiher
    New England Journal of Medicine, 2018
  • Rivaroxaban for thromboprophylaxis after hospitalization for medical illness
    Alex C. Spyropoulos, Walter Ageno, Gregory W. Albers, C. Gregory Elliott, Jonathan L. Halperin, William R. Hiatt, Gregory A. Maynard, P. Gabriel Steg, Jeffrey I. Weitz, Eunyoung Suh, Theodore E. Spiro, Elliot S. Barnathan, Gary E. Raskob
    New England Journal of Medicine, 2018
  • BIOMARKER ST2 AS A NEW PREDICTOR OF ACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE ST SEGMENT ELEVATION MYOCARDIAL INFARCTION
    Georgian Medical News, 2018
  • PROGNOSTICATION OF CLINICAL OUTCOMES AFTER STEMI: THE ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR-A
    Georgian Medical News, 2018
  • GROWTH DIFFERENTIATION FACTOR 15 AS A PROGNOSTIC MARKER OF CHRONIC HEART FAILURE PROGRESSION IN LONG-TERM FOLLOW-UP AFTER ACUTE CORONARY SYNDROME
    Georgian Medical News, 2017
  • Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes
    Rury R. Holman, M. Angelyn Bethel, Robert J. Mentz, Vivian P. Thompson, Yuliya Lokhnygina, John B. Buse, Juliana C. Chan, Jasmine Choi, Stephanie M. Gustavson, Nayyar Iqbal, Aldo P. Maggioni, Steven P. Marso, Peter Öhman, Neha J. Pagidipati, Neil Poulter, Ambady Ramachandran, Bernard Zinman, Adrian F. Hernandez
    New England Journal of Medicine, 2017
  • Comparison of fatal or irreversible events with extended-duration betrixaban versus standard dose enoxaparin in acutely Ill medical patients: An APEX trial substudy
    C. Michael Gibson, Serge Korjian, Gerald Chi, Yazan Daaboul, Purva Jain, Douglas Arbetter, Samuel Z. Goldhaber, Russel Hull, Adrian F. Hernandez, Renato D. Lopes, Alex Gold, Alexander T. Cohen, Robert A. Harrington, and
    Journal of the American Heart Association, 2017
  • Comparative analysis of oncologic outcomes of radical nephrectomy and nephron-sparing surgery in patients with intravenous extension of tumor into the renal vein
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  • Cause of death and predictors of all-cause mortality in anticoagulated patients with nonvalvular atrial fibrillation: Data from ROCKET AF
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