Nadia Emi Aikawa

Verified @gmail.com

University of Sao Paulo/ Faculdade de Medicina da Universidade de Sao Paulo
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

1: Medeiros-Ribeiro AC, Aikawa NE. Discontinuing methotrexate to enhance vaccine response. Nat Rev Rheumatol. 2022 Sep;18(9):497-498.

2: Gualano B, Lemes ÍR, da Silva RP, Pinto AJ, Mazzolani BC, Smaira FI, Sieczkowska SM, Aikawa NE, Pasoto S, Medeiros-Ribeiro AC, Saad C, Yuk E, Silva C, Swinton P, Hallal PC, Roschel H, Bonfa E. Physical activity and antibody persistence 6 months after the second dose of CoronaVac in immunocompromised patients. Scand J Med Sci Sports. 2022 Jul 17.

3: Ihara BP, Lindoso LM, Setoue DND, Tanigava NY, Helito AC, Simon JR, Viana VSL, Strabelli CAA, Pedroso CAA, Sieczkowska SM, Pereira RMR, Aikawa NE, Kozu KT, Elias AM, Buscatti IM, Gualano B, Queiroz LB, Casella CB, Polanczyk GV, Silva CAA, Campos LMMA. COVID-19 quarantine in adolescents with autoimmune rheumatic diseases: mental health issues and life conditions. Clin Rheumatol. 2022 Jun 15:1–10.

4: Piotto D, Nicacio A, Neto A, Mourão AF, Oliveira-Ramos F, Campanilho-Marques R, Guedes M, Cabral M, Santo

EDUCATION

• Master degree, Pediatric Department, University of São Paulo, São Paulo - Brazil - 2011
• PhD, Pediatric Department, University of São Paulo, São Paulo - Brazil - 2012
• Postdoctoral fellowship, University of São Paulo, São Paulo – Brazil - 2019
• Assistant physician, Rheumatology Division, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - University of São Paulo, São Paulo - Brazil 2014 to present
170

Scopus Publications

5294

Scholar Citations

38

Scholar h-index

117

Scholar i10-index

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

  • Recombinant herpes zoster vaccine in patients with autoimmune rheumatic diseases in Brazil: a double-blind, randomised, placebo-controlled, phase 4, non-inferiority study
    NE Aikawa, AC Medeiros-Ribeiro, SG Pasoto, LVK Kupa, LPC Seguro, ...
    The Lancet Rheumatology 8 (5), e363-e376 , 2026
    2026
    Citations: 3
  • Lower magnitude of humoral response to recombinant herpes zoster vaccine in immunocompromised Sjögren’s disease patients: evidence from a randomized double-blinded placebo …
    SG Pasoto, TO Ribeiro, NE Aikawa, AC Medeiros-Ribeiro, B Borges, ...
    Seminars in Arthritis and Rheumatism, 152974 , 2026
    2026
  • Prolonged skin involvement distinguishes adolescent from childhood-onset IgA vasculitis: a large multicenter study with 687 patients
    LFC Forero, PS Marra, RN Machado, CR Doria, SD Cordoba, LV Steuer, ...
    Advances in Rheumatology , 2026
    2026
  • Effect of hydroxychloroquine dose reduction (2–3 mg/kg/day) on lipoprotein levels in stable lupus nephritis: A 12-month randomized controlled longitudinal study
    DM Nunes Filho, NE Aikawa, L de Vinci Kanda Kupa, SG Pasoto, ...
    Lupus, 09612033251413980 , 2026
    2026
  • Painful subcutaneous edema is associated with early age at disease onset in Immunoglobulin A vasculitis patients: A multicenter study
    CR DORIA, MS FRANCA, PS MARRA, SD CORDOBA, LFC FORERO, ...
    ELSEVIER ESPANA , 2026
    2026
  • Painful subcutaneous edema is associated with early age at disease onset in Immunoglobulin A vasculitis patients: A multicenter study
    LV Steuer, CR Doria, MS França, PS Marra, SD Cordoba, LFC Forero, ...
    Clinics 81, 100857 , 2026
    2026
  • Efficacy of switching from originator adalimumab to biosimilar adalimumab-AACF in patients with rheumatoid arthritis: a 12-month observational study
    F Reyes-Neira, B Bayeh, KR Bonfiglioli, NE Aikawa, APL Assad, R Miossi, ...
    Advances in Rheumatology 65 (1), 46 , 2025
    2025
  • A real-life study of juvenile idiopathic arthritis from two Brazilian referral centers for pediatric rheumatology
    AML Terrazas, RG Suárez, RT Campos, CA Len, NE Aikawa, ...
    Advances in Rheumatology 65 (1), 26 , 2025
    2025
  • Quantitative PCR for parasitemia monitoring and preemptive therapy in patients with Chagas disease and autoimmune rheumatic disorders undergoing biologic treatment: a case series
    NB Carvalho, VLT Freitas, NE Aikawa, LT Vieira, RC Bezerra, ...
    Revista da Sociedade Brasileira de Medicina Tropical 58, e00802-2025 , 2025
    2025
  • POS1343 IMPACT OF HYDROXYCHLOROQUINE BLOOD LEVELS ON LIPOPROTEIN PROFILES IN JUVENILE SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS
    FAR Neira, N Aikawa, EF Borba, S Pasoto, CA Silva, V Balbi, E Bonfa, ...
    Annals of the Rheumatic Diseases 84, 1379 , 2025
    2025
  • ABS0925 DETRIMENTAL IMPACT OF RITUXIMAB ON IMMUNOGENICITY OF THE RECOMBINANT HERPES ZOSTER VACCINE: A PROSPECTIVE PHASE 4 STUDY IN AUTOIMMUNE RHEUMATIC DISEASES PATIENTS
    H Dalmolin, N Aikawa, ACM Ribeiro, APL Assad, S Pasoto, LK Kupa, ...
    Annals of the Rheumatic Diseases 84, 1636-1637 , 2025
    2025
  • Recombinant Herpes Zoster Vaccine (rzv) in a Large Cohort of Autoimmune Rheumatic Diseases Patients: A Prospective Double-Blind Randomized Placebo-Controlled Phase 4 Study
    N Aikawa, A Medeiros-Ribeiro, S Pasoto, L Kupa, LPC Seguro, AP Assad, ...
    The Journal of Rheumatology 52 (Suppl 1), 67-67 , 2025
    2025
    Citations: 1
  • Disease safety, immunogenicity, and efficacy of recombinant herpes zoster vaccine (RZV or Shingrix) in autoimmune rheumatic diseases: launching a randomized phase 4 study
    LVK Kupa, AC Medeiros-Ribeiro, NE Aikawa, SG Pasoto, EF Borba, ...
    JCR: Journal of Clinical Rheumatology, 10.1097 , 2025
    2025
    Citations: 6
  • Autoantibody clusters in childhood-onset systemic lupus erythematosus: Insights from a multicenter study with 912 patients
    VC Trindade, E Bonfá, AP Sakamoto, MT Terreri, NE Aikawa, FJ Fiorot, ...
    Lupus 34 (3), 292-299 , 2025
    2025
    Citations: 2
  • Efficacy of switching from originator adalimumab to biosimilar adalimumab-AACF in patients with axial spondyloarthritis: a 12-month observational study
    FAR Neira, B Bayeh, KR Bonfiglioli, NE Aikawa, APL Assad, R Miossi, ...
    Exploration of Musculoskeletal Diseases 3, 100783 , 2025
    2025
    Citations: 2
  • Impaired Humoral Response to Recombinant Herpes Zoster Vaccine in Rituximab Treated Autoimmune Rheumatic Diseases Patients: A Prospective Controlled Phase 4 Study
    NE AIKAWA, H DALMOLIN, SG PASOTO, AC MEDEIROS-RIBEIRO, ...
    WILEY , 2025
    2025
  • Safety and Humoral Response to Recombinant Herpes Zoster Vaccine in immunosuppressed Sjogren's Disease Patients: Results From a Double-Blinded Placebo-Controlled Study
    SG PASOTO, T RIBEIRO, NE AIKAWA, AC MEDEIROS-RIBEIRO, ...
    WILEY , 2025
    2025
  • Interim Analysis of the Impact of a Recombinant Herpes Zoster Vaccine on Systemic Lupus Erythematosus: A Randomized Controlled Study on Immunogenicity, Safety and …
    LPC SEGURO, A NEGRINI, SG PASOTO, NE AIKAWA, ...
    WILEY , 2025
    2025
  • Prospective Controlled Study of Humoral Response to Recombinant Zoster Vaccine in Cyclophosphamide-Treated Autoimmune Rheumatic Disease Patients: No Additional Impairment …
    NE AIKAWA, J MEDEIROS, SG PASOTO, AC MEDEIROS-RIBEIRO, ...
    WILEY , 2025
    2025
  • Methotrexate use and higher age impair humoral response against the recombinant herpes zoster vaccine (RZV) in Rheumatoid Arthritis: a prospective, randomized, placebo …
    AC MEDEIROS-RIBEIRO, L FARIAS, NE AIKAWA, SG PASOTO, LV KUPA, ...
    WILEY , 2025
    2025

MOST CITED SCHOLAR PUBLICATIONS

  • Autoimmune primary ovarian insufficiency
    CA Silva, LYS Yamakami, NE Aikawa, DB Araujo, JF Carvalho, E Bonfá
    Autoimmunity reviews 13 (4-5), 427-430 , 2014
    2014
    Citations: 275
  • Immunogenicity of anti-TNF-α agents in autoimmune diseases
    N Emi Aikawa, JF de Carvalho, C Artur Almeida Silva, E Bonfá
    Clinical reviews in allergy & immunology 38 (2), 82-89 , 2010
    2010
    Citations: 261
  • Immunogenicity and safety of the CoronaVac inactivated vaccine in patients with autoimmune rheumatic diseases: a phase 4 trial
    AC Medeiros-Ribeiro, NE Aikawa, CGS Saad, EFN Yuki, T Pedrosa, ...
    Nature medicine 27 (10), 1744-1751 , 2021
    2021
    Citations: 236
  • Vitamin D supplementation in adolescents and young adults with juvenile systemic lupus erythematosus for improvement in disease activity and fatigue scores: a randomized …
    GL Lima, J Paupitz, NE Aikawa, L Takayama, E Bonfa, RMR Pereira
    Arthritis care & research 68 (1), 91-98 , 2016
    2016
    Citations: 190
  • Hypertension in employees of a University General Hospital
    D Mion Jr, AMG Pierin, AP Bambirra, JH Assunção, JM Monteiro, ...
    Revista do Hospital das Clínicas 59 (6), 329-336 , 2004
    2004
    Citations: 128
  • Immunogenicity and safety of the 2009 non-adjuvanted influenza A/H1N1 vaccine in a large cohort of autoimmune rheumatic diseases
    CGS Saad, EF Borba, NE Aikawa, CA Silva, RMR Pereira, AL Calich, ...
    Annals of the rheumatic diseases 70 (6), 1068-1073 , 2011
    2011
    Citations: 124
  • Reduced seroprotection after pandemic H1N1 influenza adjuvant-free vaccination in patients with rheumatoid arthritis: implications for clinical practice
    ACM Ribeiro, LKN Guedes, JCB Moraes, CGS Saad, NE Aikawa, ...
    Annals of the rheumatic diseases 70 (12), 2144-2147 , 2011
    2011
    Citations: 110
  • Pediatric catastrophic antiphospholipid syndrome: descriptive analysis of 45 patients from the “CAPS Registry”
    H Berman, I Rodríguez-Pintó, R Cervera, S Gregory, E de Meis, ...
    Autoimmunity Reviews 13 (2), 157-162 , 2014
    2014
    Citations: 98
  • High disease activity: an independent factor for reduced immunogenicity of the pandemic influenza a vaccine in patients with juvenile systemic lupus erythematosus
    LMA Campos, CA Silva, NE Aikawa, AA Jesus, JCB Moraes, J Miraglia, ...
    Arthritis care & research 65 (7), 1121-1127 , 2013
    2013
    Citations: 98
  • Risk factors associated with calcinosis of juvenile dermatomyositis
    AME Sallum, FCMM Pivato, U Doria-Filho, NE Aikawa, BL Liphaus, ...
    Jornal de pediatria 84, 68-74 , 2008
    2008
    Citations: 97
  • TNF blockers show distinct patterns of immune response to the pandemic influenza A H1N1 vaccine in inflammatory arthritis patients
    ILA França, ACM Ribeiro, NE Aikawa, CGS Saad, JCB Moraes, ...
    Rheumatology 51 (11), 2091-2098 , 2012
    2012
    Citations: 95
  • Glucocorticoid: major factor for reduced immunogenicity of 2009 influenza A (H1N1) vaccine in patients with juvenile autoimmune rheumatic disease
    NE Aikawa, LMA Campos, CA Silva, JF Carvalho, CGS Saad, G Trudes, ...
    The Journal of rheumatology 39 (1), 167-173 , 2012
    2012
    Citations: 91
  • Discrimination of acute lymphoblastic leukemia from systemic-onset juvenile idiopathic arthritis at disease onset
    MS Tamashiro, NE Aikawa, LMA Campos, LM Cristofani, V Odone-Filho, ...
    Clinics 66, 1665-1669 , 2011
    2011
    Citations: 86
  • Influenza A/H1N1 vaccination of patients with SLE: can antimalarial drugs restore diminished response under immunosuppressive therapy?
    EF Borba, CGS Saad, SG Pasoto, ALG Calich, NE Aikawa, ACM Ribeiro, ...
    Rheumatology 51 (6), 1061-1069 , 2012
    2012
    Citations: 79
  • Two-week methotrexate discontinuation in patients with rheumatoid arthritis vaccinated with inactivated SARS-CoV-2 vaccine: a randomised clinical trial
    CSR Araujo, AC Medeiros-Ribeiro, CGS Saad, KR Bonfiglioli, ...
    Annals of the rheumatic diseases 81 (6), 889-897 , 2022
    2022
    Citations: 76
  • Management considerations for childhood-onset systemic lupus erythematosus patients and implications on therapy
    CA Silva, NE Aikawa, RMR Pereira, LMA Campos
    Expert review of clinical immunology 12 (3), 301-313 , 2016
    2016
    Citations: 69
  • Henoch-Schönlein purpura nephritis: initial risk factors and outcomes in a Latin American tertiary center
    IM Buscatti, BB Casella, NE Aikawa, A Watanabe, SCL Farhat, ...
    Clinical rheumatology 37 (5), 1319-1324 , 2018
    2018
    Citations: 67
  • Autoimmune hemolytic anemia in systemic lupus erythematosus at diagnosis: differences between pediatric and adult patients
    NWS Gormezano, D Kern, OL Pereira, GCX Esteves, AME Sallum, ...
    Lupus 26 (4), 426-430 , 2017
    2017
    Citations: 66
  • Subclinical impairment of ovarian reserve in juvenile systemic lupus erythematosus after cyclophosphamide therapy.
    NE Aikawa, AM Sallum, RM Pereira, L Suzuki, VS Viana, E Bonfá, ...
    Clinical and experimental rheumatology 30 (3), 445-449 , 2012
    2012
    Citations: 66
  • Vaccinations in juvenile chronic inflammatory diseases: an update
    CA Silva, NE Aikawa, E Bonfa
    Nature Reviews Rheumatology 9 (9), 532-543 , 2013
    2013
    Citations: 65