Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Oncology
3
Scopus Publications
19
Scholar Citations
2
Scholar h-index
1
Scholar i10-index
Scopus Publications
Lead Exposure Assessment and Its Impact on the Structural Organization and Morphological Peculiarities of Rat Ovaries Adam Osowski, Larysa Fedoniuk, Yaroslav Bilyk, Olena Fedchyshyn, Mykhailo Sas, Solomiia Kramar, Yuliia Lomakina, Volodymyr Fik, Sofija Chorniy, Joanna Wojtkiewicz Toxics, 2023 Lead is known to be highly toxic to humans, causing various disorders infetal development. An experiment was conducted to examine the effects of lead acetate on the structural organization of female rat ovaries. The study involved 40 non-linear female rats divided into four groups: a control group, a low-dose group, a moderate-dose group, and a high-dose group. The rats were given lead acetate solutions in varying doses for 30 days, and their ovarian tissue was examined using light microscopy.The results showed that increasing doses of lead acetate led to morphological changes in the cortex and medulla of the rat ovaries. The changes were characterized by a decrease in ovarian mass, alterations in the thickness of the tunica albuginea (protein envelope), and a reduction in the number of follicles. Light microscopy revealed that exposure to lead acetate resulted in a significant decrease in the number of follicles in all experimental groups, with the high-dose group experiencing the most significant decrease.These findings suggest that lead acetate has a dose-dependent negative impact on the morphology and function of female rat ovaries. Further studies are needed to investigate the potential impact of lead on human ovarian tissue.
The Role of Lyophilized Xenodermotransplants in Repairing the Atria’s Structure and the Peculiarities of Regenerative Processes after Thermal Trauma in an Experiment Adam Osowski, Iryna Hetmaniuk, Olena Fedchyshyn, Mykhailo Sas, Yuliia Lomakina, Nataliia Tkachuk, Olena Budarna, Volodymyr Fik, Larisa Fedoniuk, Joanna Wojtkiewicz Life, 2023 The effects of severe burn injuries on the cardiovascular system, specifically the atria and auricles of the heart, were investigated. The potential benefits of using lyophilized xenodermotransplants as a treatment option were also evaluated. The experiments were conducted on adult guinea pigs divided into three groups: intact animals, animals with burns, and animals with burns who underwent early necrectomy followed by wound closure with lyophilized xenodermotransplants. Third-degree burns caused significant ultrastructural changes in atrial cardiomyocytes, leading to long-term destructive changes in the structural components of the atria. However, the use of lyophilized xenodermotransplants had a positive effect on the atrial ultrastructure over time. This study highlights the complex and varied effects of burn injuries on the body and the potential benefits of lyophilized xenodermotransplants in treating severe burn injuries. By preventing destructive changes in the heart and activating regenerative processes, lyophilized xenodermotransplants can improve the condition of the heart after thermal injury. Further research and development in this area are necessary for understanding the potential of lyophilized xenodermotransplants in tissue repair and regeneration.
SYSTEM OF PROFESSIONAL COMMUNICATIVE LITERACY FORMATION FOR FUTURE MEDICAL WORKERS THROUGH THE PRISM OF LANGUAGE TRAINING Nadiya O. Fedchyshyn, Nataliia V. Chornobryva, Olena I. Fedchyshyn, Olga M. Tsaryk, Mykola P. Pantiuk, Larysa Ya. Fedoniuk, Yaryna M. Nakhaieva Wiadomosci Lekarskie Warsaw Poland 1960, 2022 The aim of the study is to analyze the formation of professional communicative literacy of future medical workers, which includes a personal development component provided by independent language preparation for the use of medical terminology. Materials and methods: The diagnostic stage, which was conducted in 2019-2020, included 400 students from four higher educational institutions: I. Horbachevsky Ternopil National Medical University, Danylo Halytsky Lviv National Medical University, Ivano-Frankivsk National University, Uzhhorod National University. These are students who completed the study of such disciplines as “Latin language and basics of medical terminology”, “Human anatomy”, “Histology”, “Pharmacology” in the 1st year of studying. Results: The comparative analysis shows that this determined the level of formation of the students’ motivational sphere in the direction of speech preparation for the use of medical terminology in Latin language classes, and the following results were obtained. With regard to the main motivating points for Latin classes, it was established that 115 (28.75%) young people study it with great interest, strive to improve their knowledge of medical terminology further, as they are sure that they will definitely need it in their future professional activities. Conclusions: Research and experimental verification of the effectiveness of pedagogical conditions and the structural-functional model of professional language training of future doctors for the use of medical terminology took place during the training of first-year-students at the higher educational establishment. Innovative methods of developing critical thinking, information and interactive technologies were used.Positive changes in the results of professional and language training of CG students (increase in average figure from 3.51 to 3.69 points) are caused by the natural influence of the traditional educational process, and changes in average figures in EG (from 3.51 to 3.92 points) show the effectiveness of implementation of defined pedagogical conditions.
RECENT SCHOLAR PUBLICATIONS
Lead exposure assessment and its impact on the structural organization and morphological peculiarities of rat ovaries A Osowski, L Fedoniuk, Y Bilyk, O Fedchyshyn, M Sas, S Kramar, ... Toxics 11 (9), 769 , 2023 2023 Citations: 12
The Role of Lyophilized Xenodermotransplants in Repairing the Atria’s Structure and the Peculiarities of Regenerative Processes after Thermal Trauma in an Experiment A Osowski, I Hetmaniuk, O Fedchyshyn, M Sas, Y Lomakina, N Tkachuk, ... Life 13 (7), 1470 , 2023 2023
System of professional communicative literacy formation for future medical workers through the prism of language training NO Fedchyshyn, NV Chornobryva, OI Fedchyshyn, OM Tsaryk, ... Wiad Lek 11, 2804-2810 , 2022 2022 Citations: 6
Модель медичної освіти у Німеччині НО Федчишин, О Федчишин, ГІ Кліщ, НІ Єлагіна ТОКІППО , 2017 2017 Citations: 1
MOST CITED SCHOLAR PUBLICATIONS
Lead exposure assessment and its impact on the structural organization and morphological peculiarities of rat ovaries A Osowski, L Fedoniuk, Y Bilyk, O Fedchyshyn, M Sas, S Kramar, ... Toxics 11 (9), 769 , 2023 2023 Citations: 12
System of professional communicative literacy formation for future medical workers through the prism of language training NO Fedchyshyn, NV Chornobryva, OI Fedchyshyn, OM Tsaryk, ... Wiad Lek 11, 2804-2810 , 2022 2022 Citations: 6
Модель медичної освіти у Німеччині НО Федчишин, О Федчишин, ГІ Кліщ, НІ Єлагіна ТОКІППО , 2017 2017 Citations: 1
The Role of Lyophilized Xenodermotransplants in Repairing the Atria’s Structure and the Peculiarities of Regenerative Processes after Thermal Trauma in an Experiment A Osowski, I Hetmaniuk, O Fedchyshyn, M Sas, Y Lomakina, N Tkachuk, ... Life 13 (7), 1470 , 2023 2023