paolo bergese

@unibs.it

Full Professor od Chemistry
Department of Molecular and Translational Medicine, Università degli Studi di Brescia, Italy

I grew up as a scientist at the bio-nano frontier, where I realized colloid and surface chemistry can raise and answer original biological questions. Today, totally fascinated by biogenic nanoparticles, I head a multidisciplinary team featuring one of the first stories of integration of chemistry, nanotechnology and molecular biology in extracellular nanoparticle research.

RESEARCH, TEACHING, or OTHER INTERESTS

General Chemistry, Physical and Theoretical Chemistry, Biotechnology, Biophysics
117

Scopus Publications

21498

Scholar Citations

42

Scholar h-index

97

Scholar i10-index

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

  • Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles
    K Normak, M Papp, C Paganini, A Zendrini, P Bergese, D Pinotsi, ...
    Advanced Healthcare Materials 15 (10), e2403991 , 2026
    2026
    Citations: 2
  • A reliable high-throughput OECT-based bioelectronic system enabling pan-specific vesicle quantification
    G Frusconi, A Musicò, A Zendrini, ZM Kovács-Vajna, L Paolini, P Bergese, ...
    Biosensors and Bioelectronics: X, 100755 , 2026
    2026
    Citations: 1
  • Ethanol-Guided Hybridization of Extracellular Vesicles with Liquid-Crystalline Lipid Nanoparticles
    V Pacciani, J Cardellini, A Balestri, M Rojas-Rodríguez, M Calamai, ...
    ACS Applied Materials & Interfaces , 2026
    2026
    Citations: 2
  • Investigating the effect of ginger-derived nanovesicles on the growth and metabolic activity of Bacteroides thetaiotaomicron : an isothermal microcalorimetric study
    F Loria, A Kattel, M Brucale, F Valle, P Bergese, EG Kobrin, A Chiesi, ...
    bioRxiv, 2026.01. 08.698378 , 2026
    2026
  • Orthogonal investigation at single-particle and ensemble levels uncovers lipoprotein-extracellular vesicle binding
    A Musicò, R Frigerio, K Normak, S Scolari, A Gori, P Arosio, A Radeghieri, ...
    Analytical Chemistry , 2026
    2026
  • Red blood cell-derived extracellular vesicles as biomaterials: the opportunity of freezing-induced accelerated aging
    L Paolini, M Romano, V Mangolini, S Tassoni, S Jiang, EL Mazzoldi, ...
    Biomaterials Science 14 (1), 122-139 , 2026
    2026
    Citations: 3
  • Spotlight on innovation: key insights from the extracellular vesicle cluster meeting at the European Innovation Council
    G Adamo, I Amarantos, I Arzimanoglou, P Bergese, B Bussolati, ...
    Cytotherapy , 2025
    2025
    Citations: 2
  • The extracellular vesicle biomolecular corona: current insights and diagnostic potential
    S Tassoni, P Bergese, A Radeghieri
    Nanomedicine 20 (16), 2013-2021 , 2025
    2025
    Citations: 11
  • A flexible separation method improves the comprehension of extracellular vesicles and exomeres’ function. Focus on metalloproteinase-9 secreted by different tumor cell lines
    F Accattatis, L Bianchi, Z Tang, F Imbò, M Brucale, F Valle, P Bergese, ...
    Atherosclerosis 407 , 2025
    2025
  • Extracellular vesicle isolation and characterization from bottlenose dolphin’s (Tursiops truncatus) breath
    V Moccia, C Centelleghe, A Zendrini, G Pesce, E Alvarez, E Esposti, ...
    Journal of Comparative Pathology 220, 58 , 2025
    2025
  • Hybrid Biogenic Lipid Nanoparticles: leveraging hybridization with Extracellular Vesicles for enhancing biocompatibility and targeting efficiency
    L Caselli, V Pacciani, J Cardellini, A Balestri, A Zendrini, L Paolini, ...
    EUROPEAN BIOPHYSICS JOURNAL 54, S55-S55 , 2025
    2025
  • Preparation and Multiscale Analytical Characterization of Nanoparticle-extracellular Vesicle Hybrids
    J Cardellini, K Normak, M Gerlt, A Bongiovanni, P Bergese, P Arosio
    EUROPEAN BIOPHYSICS JOURNAL 54, S147-S147 , 2025
    2025
  • Nanoplasmonic Isosbestics uncover mesoscale assembly of gold nanoparticles on soft templates
    J Cardellini, I De Santis, GE Lio, M Brucale, F Valle, V Catani, I Mastrolia, ...
    Journal of the American Chemical Society 147 (23), 20008-20022 , 2025
    2025
    Citations: 7
  • MicroRNA-142-3p shuttling in extracellular vesicles marks regulatory T cell dysfunction in multiple sclerosis
    G De Rosa, C Russo, S Garavelli, D Di Silvestre, I Spatocco, G Mele, ...
    Science Translational Medicine 17 (800), eadl1698 , 2025
    2025
    Citations: 6
  • Red Blood Cell-derived Extracellular Vesicles enable Cisplatin and Cetuximab combined Therapy against Triple-Negative Breast Cancer
    M Romano, A Musicò, A Zendrini, E Gilberti, F Orlandi, T Pedrazzi, ...
    bioRxiv, 2025.03. 20.644320 , 2025
    2025
  • Microfluidics‐Driven Manufacturing and Multiscale Analytical Characterization of Nanoparticle‐Vesicle Hybrids
    J Cardellini, K Normak, M Gerlt, K Makasewicz, C Seiffert, ...
    Advanced healthcare materials 14 (4), 2403264 , 2025
    2025
    Citations: 13
  • Unveiling the mesoscale assembly of gold nanoparticles on soft templates via nanoplasmonic isosbestic points
    I De Santis, J Cardellini, GE Lio, M Brucale, F Valle, V Catani, I Mastrolia, ...
    Book of Abstract-CDCF50&5thECPC Conference, 0-0 , 2025
    2025
  • The gold nanoparticle–lipid membrane synergy for nanomedical applications
    L Caselli, L Paolini, WK Fong, C Montis, A Zendrini, J Cardellini, ...
    Nanoscale Horizons 10 (9), 1863-1881 , 2025
    2025
    Citations: 13
  • Red Blood Cell-derived Extracellular Vesicles enable Cisplatin and Cetuximab Synergistic Therapy against Triple-Negative Breast Cancer
    M Romano, A Musicò, A Zendrini, E Gilberti, F Orlandi, T Pedrazzi, ...
    bioRxiv , 2025
    2025
  • Helminth extracellular vesicles co‐opt host monocytes to drive T cell anergy
    A Borup, MF Sharifpour, LS Rossen, B Whitehead, AT Boysen, R Olesen, ...
    Journal of Extracellular Vesicles 14 (1), e70027 , 2025
    2025
    Citations: 7

MOST CITED SCHOLAR PUBLICATIONS

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …
    C Théry, KW Witwer, E Aikawa, MJ Alcaraz, JD Anderson, ...
    Journal of extracellular vesicles 7 (1), 1535750 , 2018
    2018
    Citations: 12089
  • Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
    JA Welsh, DCI Goberdhan, L O'Driscoll, EI Buzas, C Blenkiron, ...
    Journal of extracellular vesicles 13 (2), e12404 , 2024
    2024
    Citations: 4071
  • Tangential flow filtration for highly efficient concentration of extracellular vesicles from large volumes of fluid
    S Busatto, G Vilanilam, T Ticer, WL Lin, DW Dickson, S Shapiro, ...
    Cells 7 (12), 273 , 2018
    2018
    Citations: 591
  • Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
    AE Russell, A Sneider, KW Witwer, P Bergese, SN Bhattacharyya, ...
    Journal of extracellular vesicles 8 (1), 1684862 , 2019
    2019
    Citations: 298
  • On the issue of transparency and reproducibility in nanomedicine
    HS Leong, KS Butler, CJ Brinker, M Azzawi, S Conlan, C Dufès, A Owen, ...
    Nature nanotechnology 14 (7), 629-635 , 2019
    2019
    Citations: 249
  • Nolte-’t Hoen EN
    C Théry, KW Witwer, E Aikawa, MJ Alcaraz, JD Anderson, ...
    Noren Hooten N , 2018
    2018
    Citations: 227
  • Residual matrix from different separation techniques impacts exosome biological activity
    L Paolini, A Zendrini, GD Noto, S Busatto, E Lottini, A Radeghieri, A Dossi, ...
    Scientific reports 6 (1), 23550 , 2016
    2016
    Citations: 208
  • AFM-based high-throughput nanomechanical screening of single extracellular vesicles
    A Ridolfi, M Brucale, C Montis, L Caselli, L Paolini, A Borup, AT Boysen, ...
    Analytical chemistry 92 (15), 10274-10282 , 2020
    2020
    Citations: 162
  • Exosome-delivered microRNAs promote IFN-α secretion by human plasmacytoid DCs via TLR7
    V Salvi, V Gianello, S Busatto, P Bergese, L Andreoli, U D’Oro, A Zingoni, ...
    JCI insight 3 (10), e98204 , 2018
    2018
    Citations: 135
  • Colorimetric nanoplasmonic assay to determine purity and titrate extracellular vesicles
    D Maiolo, L Paolini, G Di Noto, A Zendrini, D Berti, P Bergese, D Ricotta
    Analytical chemistry 87 (8), 4168-4176 , 2015
    2015
    Citations: 122
  • Embodied energy as key parameter for sustainable materials selection: The case of reusing coal fly ash for removing anionic surfactants
    A Zanoletti, S Federici, L Borgese, P Bergese, M Ferroni, LE Depero, ...
    Journal of Cleaner Production 141, 230-236 , 2017
    2017
    Citations: 98
  • Merging colloidal nanoplasmonics and surface plasmon resonance spectroscopy for enhanced profiling of multiple myeloma-derived exosomes
    G Di Noto, A Bugatti, A Zendrini, EL Mazzoldi, A Montanelli, L Caimi, ...
    Biosensors and Bioelectronics 77, 518-524 , 2016
    2016
    Citations: 98
  • Interaction of nanoparticles with lipid membranes: a multiscale perspective
    C Montis, D Maiolo, I Alessandri, P Bergese, D Berti
    Nanoscale 6 (12), 6452-6457 , 2014
    2014
    Citations: 98
  • Large‐scale production of extracellular vesicles: Report on the “massivEVs” ISEV workshop
    L Paolini, M Monguió‐Tortajada, M Costa, F Antenucci, M Barilani, ...
    Journal of Extracellular Biology 1 (10), e63 , 2022
    2022
    Citations: 86
  • Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. J Extracell Vesicles. 2024; 13 (2): e12404
    JA Welsh, DCI Goberdhan, L O’Driscoll, EI Buzas, C Blenkiron, ...
    Epub 2024/02/08. https://doi. org/10.1002/jev2. 12404 PMID: 38326288 13 (5 … , 2024
    2024
    Citations: 85
  • Fourier-transform Infrared (FT-IR) spectroscopy fingerprints subpopulations of extracellular vesicles of different sizes and cellular origin
    L Paolini, S Federici, G Consoli, D Arceri, A Radeghieri, I Alessandri, ...
    Journal of extracellular vesicles 9 (1), 1741174 , 2020
    2020
    Citations: 84
  • Microwave generated nanocomposites for making insoluble drugs soluble
    P Bergese, I Colombo, D Gervasoni, LE Depero
    Materials Science and Engineering: C 23 (6-8), 791-795 , 2003
    2003
    Citations: 84
  • The physico-chemical landscape of extracellular vesicles
    M Manno, A Bongiovanni, L Margolis, P Bergese, P Arosio
    Nature Reviews Bioengineering 3 (1), 68-82 , 2025
    2025
    Citations: 81
  • Surfactant titration of nanoparticle–protein corona
    D Maiolo, P Bergese, E Mahon, KA Dawson, MP Monopoli
    Analytical chemistry 86 (24), 12055-12063 , 2014
    2014
    Citations: 72
  • Extracellular vesicles from rat-bone-marrow mesenchymal stromal/stem cells improve tendon repair in rat Achilles tendon injury model in dose-dependent manner: A pilot study
    C Gissi, A Radeghieri, C Antonetti Lamorgese Passeri, M Gallorini, ...
    PloS one 15 (3), e0229914 , 2020
    2020
    Citations: 71

GRANT DETAILS

Biogenic Organotropic Wetsuits - BOW.
The extracellular vesicle foundry - evFOUNDRY.