Pavlo M. Skliarov

Scopus Publications

Functional activity of blood neutrophils and immune status of heifers under the influence of probiotics
Svetoslav Farafonov, Olha Yaremko, Bogdan Gutyj, Nikolay Cherniy, Volodymyr Kozyr, et al.
Veterinarska Stanica, 2025
The article is devoted to the effect of probiotics on the animal body. The purpose of the study is to study the effect of probiotics of individual strains on the functional activity of blood neutrophils and on individual parts of the immune system of the cattle body. Various probiotics are widely used in animal husbandry and make it possible to modernize existing animal husbandry regimens. The task of finding new approaches to optimizing the beneficial flora of the body is extremely relevant. The use of probiotics in livestock production is a cost-effective solution. It has been established that the use of probiotics Lactobacillus spp. and Bacillus sb. accompanied by activation of natural resistance mechanisms. Probiotics also help improve immune status, mainly due to the humoral component, tend to optimize the microbiocenosis of the colon, and have a positive effect on increasing animal productivity. The results of comprehensive studies of the state of the defense systems of the body of cattle and their changes under the influence of the drug expand and deepen the existing data on the effect of probiotics on the homeostasis of animals.
The effectiveness of an automated heat detection system in Brown Swiss heifers when using sexed semen at a large dairy unit
Roman Mylosyvyi, Pavlo Skliarov, Olena Izhboldina, Оleksandr Chernenko, Мaryna Lieshchova, et al.
Veterinarska Stanica, 2024
The identification of cows and heifers in heat and their timely artificial insemination (AI) is an important issue for large dairy units. The objective of the research was to study the efficiency of insemination of oestrous Brown Swiss heifers using am automated heat detection system (AHD) compared to heat detection by visual observation (VO). The AHD system application increased the fertility of heifers by 8.9% when using conventional semen (unsexed) and by 14.4% using sexed semen. The number of services per conception when using sexed semen decreased from 3.7±1.08 with VO to 2.4±0.68 with AHD. Two-factor analysis of variance showed that an 89% effect of managerial decisions such as the detection of heifers in heat by means of AHD and the use of sexed semen on the efficiency of insemination. This study showed that professional breeders and veterinarians should pay particular attention to AI management when making these managerial decisions in large dairy units.
Cows Postpartum Polymorbid Pathology
Journal of Advanced Veterinary Research, 2023
Colostrum Quality Assessment in Dairy Goats: Use of an On-Farm Optical Refractometer
Carlos C. Pérez-Marín, David Cano, Francisco A. Arrebola, Valerii H. Petrusha, Pavlo M. Skliarov, et al.
Biology, 2023
Failure of passive immunity transfer is one of the main causes of increased susceptibility to infectious agents in newborn kids. To ensure successful transfer of passive immunity, kids need to be fed high-quality colostrum, containing an adequate concentration of IgG. This work evaluated the quality of colostrum obtained in the first 3 days postpartum from Malagueña dairy goats. The IgG concentration in colostrum was measured using an ELISA as a reference method, and it was estimated by optical refractometer. Colostrum composition in terms of fat and protein was also determined. The mean concentration of IgG was 36.6 ± 2.3 mg/mL, 22.4 ± 1.5 mg/mL and 8.4 ± 1.0 mg/mL on days 1, 2 and 3 after parturition, respectively. Brix values obtained using the optical refractometer were 23.2%, 18.6% and 14.1% for days 1, 2 and 3, respectively. In this population, 89% of goats produced high-quality colostrum with IgG concentrations of >20 mg/mL on the day of parturition, but this percentage declined dramatically over the following 2 days. The quality of the fresh colostrum estimated with the optical refractometer was positively correlated with those obtained using ELISA (r = 0.607, p = 0.001). This study highlights the importance of feeding first-day colostrum to newborn kids and demonstrates that the optical Brix refractometer is suitable for the on-farm estimation of IgG content in colostrum.
Infrared thermography as a method of diagnosing reproductive pathologies in animals
Multidisciplinary Reviews, 2023
Impaired Reproductive Performance of Dairy Cows under Heat Stress
Agriculturae Conspectus Scientificus, 2022
Effect of Gadolinium Orthovanadate Nanoparticles on Male Rabbits’ Reproductive Performance under Oxidative Stress
Vsevolod Koshevoy, Svitlana Naumenko, Pavlo Skliarov, Kateryna Syniahovska, Galina Vikulina, et al.
World S Veterinary Journal, 2022
Oxidative stress as a leading factor of male infertility requires correction with modern pharmacological agents, particularly redox-active nanoparticles, to improve sperm quality and hormonal balance. The current experimental study aimed to investigate the effect of orthovanadate nanoparticles of rare earth elements, particularly Gadolinium, with pronounced redox properties on the reproductive function of male rabbits under oxidative stress. A total of 36 mature male Hyla rabbits were divided into three groups of intact control (n = 12) and two experimental groups, including rabbits ubder oxidative stress (n = 12), induced by the introduction of tert-Butyl hydroperoxide, and those under oxidative stress plus hydrosol of gadolinium orthovanadate nanoparticles (NPs, n = 12) intake for 14 days. There were four rabbits per three replicates in each group. Animals of all groups were kept on the same diet and had free access to water. The use of NPs led to an improvement in sperm quality indicators. There was an improvement in motility and ejaculate volume indicators (by 14.6% and 39.2%, respectively), a reduction of the content of morphologically abnormal sperm by 26.7%; normalization of sex hormones, an increase in the level of total testosterone (by 113%) with a decrease in 17-β-estradiol (by 16.5%). This sex hormones improvement led to an increase in the androgen saturation of the rabbit’s body (free androgen index at the end of the experiment was 36.5%). The obtained changes were accompanied by a decrease in the oxidative load, as evidenced by a reduced content of diene conjugates and thio-barbituric acid-reactive compounds in the blood serum of rabbits by 30.4% and 26.8%, compared to the control. At the same time, there was an increase in the antioxidant potential, especially its glutathione link – the activity of glutathione peroxidase and glutathione reductase (by 42.5% and 34.2%, respectively), and the content of reduced glutathione increased by 62.3%, compared to the indicators before the introduction of NPs. The results of the study confirmed the effectiveness of using gadolinium orthovanadate NPs to correct the reproductive function of males under oxidative stress.
Reviewing Effective Factors of Alimentary Deficiency in Animals Reproductive Functions
Pavlo Skliarov, Serhiy Fedorenko, Svitlana Naumenko, Oleksandr Onyshchenko, Alina Pasternak, et al.
World S Veterinary Journal, 2021
Animal reproduction is one of the main factors limiting the efficiency of livestock production. Its optimal level is possibly achieved when certain conditions are created for animals. As reproduction is a complex reflex process depending on neuroendocrine regulatory mechanisms, the character and strength of stimuli, which, in turn, is due to a number of factors. Under normal conditions, the body of animals is affected by many different factors, which are appropriately transformed and specified by positive or negative reactions. Inhibitory factors include air pool, saturated with harmful substances and gases, ionizing radiation, poor water quality along with altered redox properties, hypokinesia combined with poor unbalanced feeding, systematic chronic stress, presence of toxic substances in feed, and the deficiency of vitamins and other bioantioxidants in feed or their excessive spending. Of the wide range of genetic and paratypic factors of negative impacts on reproductive capacity, the most common one is alimentary, which causes impaired reproductive function due to deficiencies in the rules, regulations, and feeding regime of animals. In particular, the alimentary can be associated with both general malnutrition (starvation) and overfeeding (obesity). However, the alimentary form of infertility mostly occurs due to low-quality diets when the diet lacks vital components (mainly vitamins, macro-, and micronutrients) or the quantitative ratios of the ingredients are violated. This is possible even if the total nutritional value of the diet meets the established requirements for the physiological needs of the body. Vitamins, micro-, and macronutrients are ecologically deficient factors of disturbance of animal reproductive function, the influence of which is observed on all processes of reproduction, from fertilization to the postpartum period and the preservation of young animals. The pathogenesis of their insufficiency is associated with the violation of steroido-, gameto-, and embryogenesis and the emergence of ante-, intra-, neo- and postnatal pathologies, respectively. Therefore, treatments and prevention measures should be aimed at providing animals with biologically complete balanced feeding and replenishment of the body with vitamins and minerals. However, all these issues remain incompletely studied and need further research.
Induction and synchronization of oestrus in sheep and goats
Pavlo SKLIAROV, Carlos PÉREZ, Valerii PETRUSHA, Sergij FEDORENKO, Dmytro BILYI
Journal of Central European Agriculture, 2021
Different methods for oestrus induction and synchronization in domestic small ruminants have been developed. Seasonality and female’s status are important factors for choosing the most appropriate treatment. In the case of females during breeding season, prostaglandins can be used since functional corpus luteum must be present in the ovaries, while during non-breeding season females should be treated with progesterone-based treatments, accompanied by equine chorionic gonadotrophin (eCG), releasing hormones and other compounds. Significant spread of oestrus synchronization during and after the breeding season has been achieved by the use of intravaginal sponges impregnated with synthetic analogues of progesterone. However, the effect of hormonal drugs on the female reproductive system may manifest differently depending on the initial functional state of reproductive organs and the hormonal status, and negative consequences can be observed when drugs are wrongly administered. In addition, insufficient knowledge about the patterns of change in the reactivity of the nervous sexual centers and the corresponding reactions of the body to the administration of hormones reduces their effectiveness, which limits the widespread use. In general, the induction and synchronization of oestrus in small ruminants is an currently important direction of scientific research and an urgent problem of sheep and goat breeding, but the proposed methods require further improvement by reducing the costand increasing biosecurity and predictability of the result.
Male Infertility: Pathogenetic Significance of Oxidative Stress and Antioxidant Defence (Review)
Vsevolod Koshevoy, Svitlana Naumenko, Pavlo Skliarov, Serhiy Fedorenko, Lidia Kostyshyn
Scientific Horizons, 2021
The basis of the pathogenesis of male infertility is the processes of peroxide oxidation of biological substrates, especially lipids and proteins. By destroying the sperm membrane, toxic peroxidation products reduce its motility and ability to fertilize the egg, which is determined by a decrease in the number of motile sperm in the ejaculate. These changes lead to complete or partial male infertility. The authors of the review found that is accompanied by a damaging effect on the structural and functional activity of the gonads and is manifested, in particular, by an imbalance in the hormonal background of the male body. Similar effects are characteristic of an increase in the content of reactive Nitrogen species and its metabolites, which cause nitrosative stress, which is also the cause of male hypofertility and is inseparable from the state of oxidative stress. In scientific work it is determined that the accumulation of harmful peroxidation products leads to damage and destruction of sperm DNA, reduced activity of acrosomal enzymes and mitochondrial potential of sperm, reduced overall antioxidant activity. This makes it impossible for an adequate response of the body. Multi component antioxidant defense system resists stress. It is represented by enzymatic and non-enzymatic links, which can neutralize harmful radicals and peroxidation products. It contributes to the full manifestation of reproductive function. The presence of powerful antioxidant properties of catalase, superoxide dismutase, and enzymes of the thiol-disulfide system, which form the enzymatic system of antioxidant protection, as well as selenium, zinc, copper, other trace elements, retinol, tocopherol, ascorbic acid, and vitamins as parts of the non-enzymatic system is shown. The efficiency of registration is substantiated thin biochemical shift detectors or complex methods, such as total antioxidant status of sperm or sperm plasma, mitochondrial membrane potential, etc along with simple markers of oxidative stress, such as diene conjugates, malonic dialdehyde, and metabolites of the Nitrogen Oxide cycle. Given the leading role of oxidative stress in the development of male hypofertility, the prospect of further research is the search for modern means for correction, especially among substances with pronounced redox activity
The Development of Phyto- And Tissue Origin Medicines for Veterinary Reproductive Issues
Pavlo Skliarov, Serhiy Fedorenko, Svitlana Naumenko, Vsevolod Koshevoy, Kateryna Pelyh
Scientific Horizons, 2021
Prognostic markers of canine mammary tumours: Retrospective study of 142 cases
M. S. Kovalenko, D. D. Bilyi, P. M. Skliarov, S. N. Maslikov, N. I. Suslova, et al.
Regulatory Mechanisms in Biosystems, 2021
Effectiveness of using the drug "Bolus rozröd +" for prevention of obstetric polymorbid pathology of cows
Olexandr Zubkov, Pavlo Skliarov
Scientific Horizons, 2020
Retinol deficiency in animals: Etiopathogenesis and consequences
P. M. Skliarov, S. Y. Fedorenko, S. V. Naumenko, O. V. Onischenko, K. О. Holda
Regulatory Mechanisms in Biosystems, 2020
Effect of β-mannanase enzyme supplementation on the morphofunctional state of broiler chickens' immunocompetent organs
A. V. Oliyar, P. M. Skliarov, D. M. Masiuk, D. D. Bilyi, V. V. Logvinova, et al.
Regulatory Mechanisms in Biosystems, 2020

RECENT SCHOLAR PUBLICATIONS

THE PIVOTAL ROLE OF RETINOL IN TNSURING REPRODUCTIVE HEALTH IN ANIMALS
P Skliarov, S Fedorenko
Publishing House “Baltija Publishing” , 2026
2026
Prevention of nutritional infertility in cows and heifers: A review
PM Skliarov, SV Naumenko, SY Fedorenko, DD Bilyi, VV Vakulyk, ...
Scientific Messenger of Lviv National University of Veterinary Medicine and … , 2026
2026
Клінічна корекція екологічних деструкцій антропогенного походження у свійських тварин Придніпровського промислового регіону
ПМ Скляров, ДД Білий, ВВ Вакулик, ЛВ Корейба, ВВ Самойлюк, ...
Дніпровський ДАЕУ; Журфонд , 2026
2026
Використання цифрової системи COWMANAGER та функції Find My Cow у ветеринарному контролі стану здоров’я молочних корів
ЮВ Слонь, ПМ Скляров
АКТУАЛЬНІ ПИТАННЯ ВЕТЕРИНАРНОЇ МОРФОЛОГІЇ, ПАТОЛОГІЇ ТА БІОТЕХНОЛОГІЇ, 202 , 2026
2026
Морфометричні показники ембріогенезу нутрій за даними ультрасонографії
ПМ Скляров, ВВ Вакулик, АВ Оліяр, ММ Шкваря, НВ Кацемба
Дніпровський ДАЕУ , 2026
2026
Етіопатогенетичні аспекти неплідності корів за дисбалансу кобальту та вітаміну В12
ПМ Скляров, ЮМ Науменко
АКТУАЛЬНІ ПИТАННЯ ВЕТЕРИНАРНОЇ МОРФОЛОГІЇ, ПАТОЛОГІЇ ТА БІОТЕХНОЛОГІЇ, 201 , 2026
2026
ОСОБЛИВОСТІ ПОСТНАТАЛЬНОГО МОРФОГЕНЕЗУ СЕЛЕЗІНКИ В СВИНІ СВІЙСЬКОЇ
А Оліяр, П Скляров, Д Білий
Аграрний вісник Причорномор'я, 153-172 , 2025
2025
DETERMINATION OF THE FERTILE PERIOD IN THE BITCH
P Skliarov
European Science, 40-59 , 2025
2025
Нозологічний профіль офтальмологічної і стоматологічної патології собак і кішок у місті Дніпро
VV Samoilіuk, PM Skliarov, DV Masiuk, MO Lieshchova, VV Vakulіk, ...
Ветеринарія, технології тваринництва та природокористування, 126-134 , 2025
2025
Профілактика аліментарної неплідності корів та телиць: огляд.
ПМ Скляров, СВ Науменко, СЮ Федоренко, ДД Білий, ВВ Вакулик, ...
Scientific Messenger of Lviv National University of Verterinary Medicine … , 2025
2025
Аналітична оцінка схем знеболювання за стоматологічних хвороб у собак
D Bilyi, P Skliarov, D Masiuk, V Samoilіuk, M Lieshchova, V Vakulik, ...
Scientific Progress & Innovations 28 (3), 250-255 , 2025
2025
Визначення причин порушення репродуктивної функції нутрій
PM Skliarov, VV Vakulyk, RV Mylostyvyi, LV Koreyba, VV Samoilіuk, ...
Ветеринарія, технології тваринництва та природокористування, 168-175 , 2025
2025
Cardioprotective effects of L-arginine in a mesatone-induced rat model of chronic heart failure: biochemical and electrocardiographic insights
RV Mylostyvyi, MO Lieshchova, PМ Skliarov, NI Suslova, OV Yanovska, ...
Ukrainian Journal of Veterinary and Agricultural Sciences 8 (1), 70-76 , 2025
2025
Огляд систем контролю поведінки тварин на ринку України з коротким описом принципу роботи та технічною характеристикою
Y Slon, P Skliarov
Scientific Progress & Innovations 28 (1), 128-140 , 2025
2025
Визначення оптимального часу осіменіння сук
ПМ Скляров
2025
Нозологічний профіль офтальмологічної і стоматологічної патології собак і кішок у місті Дніпро
ВВ Самойлюк, ПМ Скляров, ДМ Масюк, МО Лєщова, ВВ Вакулик, ...
Державний біотехнологічний університет , 2025
2025
Аналітична оцінка схем знеболювання за стоматологічних хвороб у собак
ДД Білий, ПМ Скляров, ДМ Масюк, ВВ Самойлюк, МО Лєщова, ...
Полтавський державний аграрний університет , 2025
2025
Визначення причин порушень репродуктивної функції нутрій
ПМ Скляров, ВВ Вакулик, РВ Милостивий, ЛВ Корейба, ВВ Самойлюк, ...
Державний біотехнологічний університет , 2025
2025
Експериментальні аспекти застосування методів діагностики та лікування продуктивних тварин у земських губерніях Подніпрянської України
VV Vakulyk, PM Skliarov, DD Bilyi, VV Samoilіuk, SM Maslikov, ...
2025
Порівняльна ефективність етіотропних препаратів за лікування та профілактики гастро-ентерального синдрому курчат-бройлерів в умовах приватного господарства
ММ Шкваря, НІ Cуслова, ОВ Семьонов, НМ Тішкіна, Е Єсіна, ...
Одеський ДАУ , 2025
2025

MOST CITED SCHOLAR PUBLICATIONS

Проблеми відтворення овець і кіз та шляхи іх вирішення
ВП Кошевой
ВП Кошевого.–Х.-Д.: Гамалія, 9-135 , 2011
2011
Citations: 59
Impaired Reproductive Performance of Dairy Cows under Heat Stress
MR Skliarov Pavlo, Kornienko Valentуna, Midyk Svitlana
Agriculturae Conspectus Scientificus. 87 (2), 85-92 , 2022
2022
Citations: 44
Induction and synchronization of oestrus in sheep and goats
BD SKLIAROV Pavlo, PÉREZ Carlos, PETRUSHA Valerii, FEDORENKO Sergij
Journal of Central European Agriculture 22 (1), 39-53 , 2021
2021
Citations: 42
Effect of Gadolinium Orthovanadate Nanoparticles on Male Rabbits' Reproductive Performance under Oxidative Stress
YS Koshevoy V., Naumenko S., Skliarov P., Syniahovska K., Vikulina G ...
World's Veterinary Journal 12 (3), 296-303 , 2022
2022
Citations: 37
Male Infertility: Pathogenetic Significance of Oxidative Stress and Antioxidant Defence (Review)
KL Koshevoy Vsevolod, Naumenko Svitlana, Skliarov Pavlo, Fedorenko Serhiy
Scientific Horizons 24 (6), 107-116 , 2021
2021
Citations: 35
Oxidant/antioxidant balance in cows and sheep in antenatal pathology
P Sklyarov, S Fedorenko, S Naumenko, P Antonenko, V Zazharskyi, ...
Ukrainian Journal of Ecology 10 (5), 26-28 , 2020
2020
Citations: 34
Effect of herbal feed additives on the quality of colostrum, immunological indicators of newborn calves blood and growth energy of young animals
VS Kozyr, PP Antonenko, RV Mylostyvyi, NI Suslova, PM Skliarov, ...
Theoretical and Applied Veterinary Medicine , 2019
2019
Citations: 28
The impact of lateral localization of the procedure on the effectiveness of transplations of pre-implantation embryos in heifers-recipient
L Roman, S Sidashova, I Popova, N Stepanova, V Chornyi, P Sklyarov, ...
Ukrainian journal of Ecology 10 (6), 121-126 , 2020
2020
Citations: 19
Colostrum Quality Assessment in Dairy Goats: Use of an On-Farm Optical Refractometer
PMDC Pérez-Marín C.C., Cano D., Arrebola F.A., Petrusha V.H., Skliarov P.M ...
Biology 12 (4), 626 (1-10) , 2023
2023
Citations: 18
Impact of heat stress on blood serum cortisol level in dairy cows
RV Mylostyvyi, M Wrzecińska, M Samardžija, BV Gutyj, VH Yefimov, ...
Theoretical and applied veterinary medicine 12 (4), 3-8 , 2024
2024
Citations: 17
Reviewing effective factors of alimentary deficiency in animals reproductive functions
BO 10. Skliarov P., Fedorenko S., Naumenko S., Onyshchenko O., Pasternak A ...
World’s Veterinary Journal 11 (2), 157-169 , 2021
2021
Citations: 17
Retinol deficiency in animals: Etiopathogenesis and consequences
KОH P.M. Skliarov, S.Y. Fedorenko, S.V. Naumenko, O.V. Onischenko
Regulatory Mechanisms in Biosystems 11 (2), 162–169 , 2020
2020
Citations: 17
Determining the optimal insemination time of bitches
P Skliarov, O Holubiev, R Mylostyvyi
FAVE Sección Ciencias Veterinarias 21, e0005 , 2022
2022
Citations: 15
Comparative analysis of the criteria for goat milk assessment in Ukraine and France
N Zazharska, T Fotina, I Yatsenko, L Tarasenko, I Biben, V Zazharskyi, ...
Ukrainian Journal of Ecology 11 (2), 144-148 , 2021
2021
Citations: 15
The influence of the season on the efficiency of fertilization and the manifestation of postpartum pathology in dairy cows
IO Mylostyvyi Roman, Кalinichenko Olena, Skliarov Pavlo, Lesnovskay Olena ...
Ukrainian Journal of Ecology 11 (4), 81-86 , 2021
2021
Citations: 14
The development of phyto-and tissue origin medicines for veterinary reproductive issues
P Skliarov, S Fedorenko, S Naumenko, V Koshevoy, K Pelyh
2021
Citations: 12
Structure and prevalence of multiple organ pathology of cows of the postpartum period
OO Zubkov, PM Sklyarov
Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies, 145 , 2017
2017
Citations: 11
Довідник з технології та менеджменту в тваринництві: навч. посіб. для підготов. фахівців у аграрних вищ. навч. закл. III-IV рівнів акредитації із спец. "Зооінженерія"
ВОГ Д.І. Барановський, В.І. Герасимов
Харків : Еспада , 2002
2002
Citations: 10
Infrared thermography as a method of diagnosing reproductive pathologies in animals
P Sklyarov, P Sklyarov, PM Sklyarov, PM Skliarov, P Sklyarov, P Skliarov, ...
Malque Publishing , 2023
2023
Citations: 9
Clinical significance o f measuring fatty acids in biological fluids of dair y cows (in blood and milk) with a focus on heat stress
R Mylostyvyi, O Izhboldina, S Midyk, N Cherniy, М Lieshchova, P Skliarov, ...
Multidisciplinary Reviews 5 (2), e2022011 , 2022
2022
Citations: 8

Pavlo M. Skliarov

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Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS