Dr. Pawan Kumar Gupta

EDUCATION

B. Pharm. 2005
MS Pharm 2007 (From NIPER SAS Nagar)
PhD 2012 (From NIPER SAS Nagar)

RESEARCH, TEACHING, or OTHER INTERESTS

Drug Discovery, Cancer Research, General Pharmacology, Toxicology and Pharmaceutics, Biophysics

RECENT SCHOLAR PUBLICATIONS

ROS in Precision Medicine in Neurological Diseases: Personalized Approaches
Y Chaudhari, N Patil, A Rashid, P Gupta*, R Wanjari, P Prabhakar
The Role of Reactive Oxygen Species in Human Health and Disease, 475-506 , 2025
2025
Citations: 2
Environmental Exposure and Oxidative Stress: Effects on Human Health
A Rashid, P Gupta*, Y Chaudhari, T Devadoss, R Garg, R Wanjari
The Role of Reactive Oxygen Species in Human Health and Disease, 137-172 , 2025
2025
Citations: 3
ROS and Precision Medicine in Life Style Diseases: Personalized Approaches
P Gupta*, Y Chaudhari, A Joseph, S Sinha, A Rashid, P Prabhakar
The Role of Reactive Oxygen Species in Human Health and Disease, 441-474 , 2025
2025
Citations: 3
Novel peptide inhibitor of human tumor necrosis factor-α has antiarthritic activity
D Sahu, C Gupta, RM Yennamalli, S Sharma, S Roy, S Hasan, P Gupta, ...
Scientific Reports 14 (1), 12935 , 2024
2024
Citations: 7
Current Expansion of Silver and Gold Nanomaterials towards Cancer Theranostics: Development of Therapeutics
P Gupta*, K Mishra, AK Mittal, N Handa, MK Paul
Current Nanoscience 20 (3), 356-372 , 2024
2024
Citations: 14
Novel scaffolds identification against Mpro of SARS-CoV-2 using shape based screening and molecular simulation methods
P Gupta, U Panwar, S Singh
Chemical Physics Impact, 100496 , 2024
2024
Citations: 17
Himalayan Pyracantha crenulata (D. Don) M. Roem. leaf and fruit extracts alleviate algesia through COX-2 and Mu-opioid receptor mediated pathways
D Tewari, S Bawari, AN Sah, H Sharma, BC Joshi, P Gupta, VK Sharma
Journal of Ethnopharmacology 318 (Part B), 117004 , 2024
2024
Citations: 11
Identification of novel PPAR-γ agonist ameliorating triple negative breast cancer by in silico methods
L Aishwarya, G Jeena, G Pawan
Research Journal of Biotechnology 19 (3), 58-69 , 2024
2024
Citations: 2
Metabolomics‐based pharmaceutical evaluation of different parts of Swertia chirayita (Roxb.) Buch.‐Ham. ex CB Clarke from the western Himalayas
D Tewari, S Bawari, ST Mishra, P Gupta, Z Cziáky, J Jeko, I Lazarova, ...
Journal of Separation Science 47 (1), 2300795 , 2024
2024
Citations: 5
Crystal polymorphism: Applications and future prospects
AA Malik, P Gupta, A Joseph
AIP Conference Proceedings 2800 (1), 020039-1–020039-14 , 2023
2023
Citations: 3
Himalayan Citrus jambhiri juice reduced renal crystallization in nephrolithiasis by possible inhibition of glycolate oxidase and matrix metalloproteinases
S Bawari, AN Sah, P Gupta, G Zengin, D Tewari
Journal of Ethnopharmacology 306, 116157 , 2023
2023
Citations: 13
Rational computational approaches in drug discovery: potential inhibitors for allosteric regulation of mutant isocitrate dehydrogenase-1 enzyme in cancers
M Thamim, AK Agrahari, P Gupta, K Thirumoorthy
Molecules 28 (5), 2315 , 2023
2023
Citations: 11
In silico phytochemical repurposing of natural molecules as entry inhibitors against RBD of the spike protein of SARS-CoV-2 using molecular docking studies
P Gupta, S Gupta, S Sinha, S Sundaram, VK Sharma, A Munshi
International Journal of Computational Biology and Drug Design 15 (4), 267-288 , 2023
2023
Citations: 4
Target-based in-silico screening of basil polysaccharides against different epigenetic targets responsible for breast cancer
N Bhura, P Gupta, J Gupta
Journal of Receptors and Signal Transduction 42 (5), 521-530 , 2022
2022
Citations: 5
Biodegradation of natural rubber by fungi and bacteria
A Joseph, P Gupta, G De, M Lal, MK Meena, LP Singh, J Rattan
Nature Environment and Pollution Technology 21 (3), 1039-1048 , 2022
2022
Citations: 15
Aquaporin Mediated Transport: Insights into Metalloid Trafficking
N Handa, P Gupta, K Khanna, SK Kohli, R Bhardwaj, P Ahmad
Physiologia Plantarum 174 (3), e13687,https://doi.org/10.1111/ppl.13687 , 2022
2022
Citations: 16
Withania somnifera (L.) Dunal: Phytochemistry, structure-activity relationship, and anticancer potential
D Tewari, V Chander, A Dhyani, S Sahu, P Gupta, P Patni, LS Kalick, ...
Phytomedicine 98, 153949 , 2022
2022
Citations: 80
Himalayan Ficus palmata L. Fruit Extract Showed In Vivo Central and Peripheral Analgesic Activity Involving COX-2 and Mu Opioid Receptors
D Tewari, P Gupta, S Bawari, AN Shan, D Barreca, M Khayatkashani, ...
Plants 10 (8), 1685 https://doi.org/10.3390/plants10081 , 2021
2021
Citations: 18
Virtual structural similarity elucidates bioactivity of fenchone: A phytochemical enriched in fennel essential oil
S Singh, P Gupta, J Gupta
Current Drug Discovery Technologies 17 (5), 619-630 , 2020
2020
Citations: 13
In silico, in-vitro and in vivo screening of biological activities of citral
S Habib, P Gupta, SS Bhat, J Gupta
International Journal for Vitamin and Nutrition Research 91 (3-4), 251-260 … , 2020
2020
Citations: 25

MOST CITED SCHOLAR PUBLICATIONS

Citrus medica: Nutritional, phytochemical composition and health benefits-a review
N Chhikara, R Kour, S Jaglan, P Gupta, Y Gat, A Panghal
Food & Function, http://dx.doi.org/10.1039/C7FO02035J , 2018
2018
Citations: 268
Withania somnifera (L.) Dunal: Phytochemistry, structure-activity relationship, and anticancer potential
D Tewari, V Chander, A Dhyani, S Sahu, P Gupta, P Patni, LS Kalick, ...
Phytomedicine 98, 153949 , 2022
2022
Citations: 80
Toxicophore exploration as a screening technology for drug design and discovery: techniques, scope and limitations
PK Singh, A Negi, PK Gupta, M Chauhan, R Kumar
Archives of toxicology DOI 10.1007/s00204-015-1587-5 , 2015
2015
Citations: 65
Phytochemical Repurposing of Natural Molecule: Sabinene for Identification of Novel Therapeutic Benefits Using In Silico and In Vitro Approaches
S Sharma, J Gupta, PK Prabhakar, P Gupta, P Solanki, A Rajput
ASSAY and Drug Development Technologies 17 (8), 339-351 , 2019
2019
Citations: 63
The Genus Calophyllum: Review of Ethnomedicinal uses, Phytochemistry, Pharmacology and Agronomy
S Gupta, P Gupta
Bioactive Natural products in Drug Discovery, 215–242 , 2020
2020
Citations: 62
Docking-based 3D-QSAR study of HIV-1 integrase inhibitors
P Gupta, N Roy, P Garg
European journal of medicinal chemistry 44 (11), 4276-4287 , 2009
2009
Citations: 60
Essential Oils: Biological Activity Beyond Aromatherapy
S Kar, J Gupta, Pawan Gupta
Natural Product Sciences 24 (3), 139-147 , 2018
2018
Citations: 51
Endogenous Repair System of Oxidative Damage of DNA
A Sharma, P Gupta, PK Prabhakar
Current Chemical Biology, DOI:10.2174/221279681366619022115290 , 2019
2019
Citations: 50
Identification of Novel HIV‐1 Integrase Inhibitors Using Shape‐Based Screening, QSAR, and Docking Approach
P Gupta, P Garg, N Roy
Chemical Biology & Drug Design 79 (5), 835-849 , 2012
2012
Citations: 42
Design and synthesis of caffeoyl-anilides as portmanteau inhibitors of HIV-1 integrase and CCR5
HS Bodiwala, S Sabde, P Gupta, R Mukherjee, R Kumar, P Garg, ...
Bioorganic & Medicinal Chemistry 19 (3), 1256-1263 , 2010
2010
Citations: 42
Comparative docking and CoMFA analysis of curcumine derivatives as HIV-1 integrase inhibitors
P Gupta, P Garg, N Roy
Molecular Diversity 15, 733-750 , 2011
2011
Citations: 40
Molecular mechanism of polyvinyl alcohol mediated prevention of aggregation and stabilization of insulin in nanoparticles
S Rawat, P Gupta, A Kumar, P Garg, CR Suri, DK Sahoo
Molecular Pharmaceutics, DOI: 10.1021/mp5003653 , 2015
2015
Citations: 27
Prediction of drug-resistance in HIV-1 subtype C based on protease sequences from ART naive and first-line treatment failures in North India using genotypic and docking analysis
JS Toor, A Sharma, R Kumar, P Gupta, P Garg, SK Arora
Antiviral Research 92 (2), 213-218 , 2011
2011
Citations: 26
In silico, in-vitro and in vivo screening of biological activities of citral
S Habib, P Gupta, SS Bhat, J Gupta
International Journal for Vitamin and Nutrition Research 91 (3-4), 251-260 … , 2020
2020
Citations: 25
QSAR study of curcumine derivatives as HIV-1 integrase inhibitors
P Gupta, A Sharma, P Garg, N Roy
Current computer-aided drug design 9 (1), 141-150 , 2013
2013
Citations: 24
In silico screening for identification of novel HIV-1 integrase inhibitors using QSAR and docking methodologies
P Gupta, P Garg, N Roy
Medicinal Chemistry Research, DOI 10.1007/s00044-013-04 , 2013
2013
Citations: 24
Active site binding modes of dimeric phloroglucinols for HIV-1 reverse transcriptase, protease and integrase
P Gupta, R Kumar, P Garg, IP Singh
Bioorganic & medicinal chemistry letters 20 (15), 4427-4431 , 2010
2010
Citations: 22
Himalayan Ficus palmata L. Fruit Extract Showed In Vivo Central and Peripheral Analgesic Activity Involving COX-2 and Mu Opioid Receptors
D Tewari, P Gupta, S Bawari, AN Shan, D Barreca, M Khayatkashani, ...
Plants 10 (8), 1685 https://doi.org/10.3390/plants10081 , 2021
2021
Citations: 18
Novel scaffolds identification against Mpro of SARS-CoV-2 using shape based screening and molecular simulation methods
P Gupta, U Panwar, S Singh
Chemical Physics Impact, 100496 , 2024
2024
Citations: 17
PPARγ: Potential therapeutic target for ailments beyond diabetes and its natural agonism
S Shafi, P Gupta, GL Khatik, J Gupta
Current Drug Targets 20 (12), 1281-1294 , 2019
2019
Citations: 17

GRANT DETAILS

DST-SERB: Completed