Minimally-invasive electrical impedance spectroscopy in lung tissue: present and future trends Pere J. Riu, Georgina Company-Se, Albert Rafecas Codern, Anna Farrés Castany, Virginia Pajares, et al. Journal of Physics Conference Series, 2025 Electrical impedance measurements performed in-vivo and in-situ in lung tissue so far have focused on detecting different pathologies, including neoplasm. Once its ability for this has been established, the authors intend to investigate whether it is possible to detect peripheral lung nodules. The preliminary measurements collected show differences in the measured spectra and model parameters between the different types of lesions collected (solid nodules, partially solid nodules and ground-glass nodules).
Differentiation using minimally-invasive bioimpedance measurements of healthy and pathological lung tissue through bronchoscopy Georgina Company-Se, Lexa Nescolarde, Virginia Pajares, Alfons Torrego, Pere J. Riu, et al. Frontiers in Medicine, 2023 PurposeTo use minimally-invasive transcatheter electrical impedance spectroscopy measurements for tissue differentiation among healthy lung tissue and pathologic lung tissue from patients with different respiratory diseases (neoplasm, fibrosis, pneumonia and emphysema) to complement the diagnosis at real time during bronchoscopic procedures.MethodsMulti-frequency bioimpedance measurements were performed in 102 patients. The two most discriminative frequencies for impedance modulus (|Z|), phase angle (PA), resistance (R) and reactance (Xc) were selected based on the maximum mean pair-wise Euclidean distances between paired groups. One-way ANOVA for parametric variables and Kruskal–Wallis for non-parametric data tests have been performed with post-hoc tests. Discriminant analysis has also been performed to find a linear combination of features to separate among tissue groups.ResultsWe found statistically significant differences for all the parameters between: neoplasm and pneumonia (p < 0.05); neoplasm and healthy lung tissue (p < 0.001); neoplasm and emphysema (p < 0.001); fibrosis and healthy lung tissue (p ≤ 0.001) and pneumonia and healthy lung tissue (p < 0.01). For fibrosis and emphysema (p < 0.05) only in |Z|, R and Xc; and between pneumonia and emphysema (p < 0.05) only in |Z| and R. No statistically significant differences (p > 0.05) are found between neoplasm and fibrosis; fibrosis and pneumonia; and between healthy lung tissue and emphysema.ConclusionThe application of minimally-invasive electrical impedance spectroscopy measurements in lung tissue have proven to be useful for tissue differentiation between those pathologies that leads increased tissue and inflammatory cells and those ones that contain more air and destruction of alveolar septa, which could help clinicians to improve diagnosis.
Numerical assessment in aeronautics for electromagnetic environmental effects Miguel David Ruiz-Cabello Nuñez, Sergio Fernández Romero, Marc Pous, Enrique Pascual Gil, Luis M. Diaz Angulo, et al. Electromagnetic Compatibility for Space Systems Design, 2018 Electrical and electronic systems on board air vehicles are susceptible to electromagnetic interference (EMI). This has made the topic of electromagnetic compatibility (EMC), a major concern for aircraft safety. The use of composite materials worsens this situation, for their poor shielding and low conductive capabilities. Some of the main experimental E3 certification scenarios used in aeronautics are revisited in this chapter. Guidelines to achieve simple, yet accurate, numerical models of them are provided, with appropriate tradeoffs between computational simplicity and accuracy. The numerical method, endowed with extended capabilities, has been chosen for this task for its ability and efficiency to deal with complex problems of arbitrary materials. The feature selective validation (FSV) IEEE standard procedure, commonly used to quantify the comparison of data in electromagnetic problems, is also revisited. The simulation of three different air vehicles in several certification scenarios is finally described and the numerical results compared to experimental data.
FDTD Analysis of SAR from a Cell Phone Inside a Vehicle Gabriel Anzaldi, Eduard Canela Delgado, Pere J. Riu, Ferran Silva Proceedings of the 16th International Zurich Symposium on Electromagnetic Compatibility EMC 2005, 2005
Remotely accessible laboratory for instrumentation and sensors Conference Record IEEE Instrumentation and Measurement Technology Conference, 2004
Finite difference time domain low cost modeling for automotive environments IEEE International Symposium on Electromagnetic Compatibility, 2004
Semi-distance Learning vs. Traditional Organisation for a Master's Degree in Electronic Engineering: An Experience at the Technical University of Catalonia (UPC), Spain International Journal of Engineering Education, 2004
Bioelectrical Impedance Vector Analysis in COPD Patients Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings, 2003
A LOW-COST ANALOG FIBER OPTIC LINK FOR EMC APPLICATIONS Francese J. Sánchez, Pere J. Riu, Marcos Quílez, Ferran Silva 15th International Zurich Symposium and Technical Exhibition on Electromagnetic Compatibility EMC 2003, 2003
42 v Automobile EMI Measurements Salvador Verdaguer, Marcos Quílez, Mireya Fernández, Pere Riu, Ferran Silva International Symposium on Electromagnetic Compatibility 2002 EMC Europe Sorrento, 2002
Low-cost near-field probe for simultaneous E and H measurement with analog optical link IEEE International Symposium on Electromagnetic Compatibility, 1997
Quantification improvement in EIT reconstruction algorithms by incorporating a priori geometrical information Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings, 1996
Education in instrumentation: some questions and answers IEE Colloquium Digest, 1996
Education in instrumentation: Some questions and answers IEE Colloquium Digest, 1996
Changes in myocardial impedance spectrum during acute ischemia in the in-situ pig heart Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings, 1996
Parallel data acquisition system for electrical impedance tomography Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings, 1989
Skin Impedance From 1 Hz to 1 MHz J. Rosell, J. Colominas, P. Riu, R. Pallas-Areny, J.G. Webster IEEE Transactions on Biomedical Engineering, 1988
RECENT SCHOLAR PUBLICATIONS
Electromagnetic navigation-guided electronic lung biopsy with electrical impedance spectroscopy: a feasibility study in peripheral pulmonary nodules. A Rafecas-Codern, L Nescolarde, A Farrés-Castany, P Serra, M Navarro, ... European Respiratory Journal 66 (suppl 69) , 2025 2025 Citations: 2
Feasibility of electrical impedance spectroscopy for tissue differentiation in peripheral solitary pulmonary nodules and masses L Nescolarde, G Company-Se, A Rafecas, A Farrés-Castany, V Pajares, ... 2025 47th Annual International Conference of the IEEE Engineering in … , 2025 2025
Minimally-invasive electrical impedance spectroscopy in lung tissue: present and future trends PJ Riu, G Company-Se, AR Codern, AF Castany, V Pajares, J Rosell, ... Journal of Physics: Conference Series 3014 (1), 012004 , 2025 2025
Machine learning allows robust classification of lung neoplasm tissue using an electronic biopsy through minimally-invasive electrical impedance spectroscopy G Company-Se, V Pajares, A Rafecas-Codern, PJ Riu, J Rosell-Ferrer, ... Scientific reports 15 (1), 9716 , 2025 2025
Involvement of the Lung Parenchyma Analyzed by Frequency Components of the Tidal Volume Assessed by Electrical Bioimpedance FM Vargas Luna, MI Delgadillo Cano, PJ Riu Costa, S Kashina, ... Revista mexicana de ingeniería biomédica 45 (2), 23-34 , 2024 2024 Citations: 1
Assessing Pulmonary Function Parameters Non-invasively by Electrical Bioimpedance Tomography FM Vargas-Luna, MI Delgadillo-Cano, JP Riu-Costa, S Kashina, ... Journal of Medical and Biological Engineeri g , 2023 2023 Citations: 6
Relaxation differences using EIS through bronchoscopy of healthy and pathological lung tissue G Company-Se, L Nescolarde, V Pajares, A Torrego, A Rafecas, J Rosell, ... 2023 45th Annual International Conference of the IEEE Engineering in … , 2023 2023 Citations: 1
ANNEX 3: Relaxation differences using EIS through bronchoscopy of healthy and pathological lung tissue AT Pajares, A Rafecas, J Rosell, PJ Riu, R Bragós Temporal and frequency differentiation of healthy and pathological lung … , 2023 2023
Application of Machine Learning Classification Algorithms in Lung Electrical Impedance Spectroscopy Measurements AR Pajares, PJ Riu, J Rosell, R Bragós Temporal and frequency differentiation of healthy and pathological lung … , 2023 2023
Differentiation using minimally-invasive bioimpedance measurements of healthy and pathological lung tissue through bronchoscopy G Company-Se, L Nescolarde, V Pajares, A Torrego, PJ Riu, J Rosell, ... Frontiers in medicine 10, 1108237 , 2023 2023 Citations: 5
Relaxation differences using EIS through bronchoscopy of healthy and pathological lung tissue LD Nescolarde Selva, V Pajares Ruiz, A Torrego Fernández, A Rafecas, ... EMBC 2023-45th Annual International Conference of the IEEE Engineering in … , 2023 2023
Diferenciación por métodos estadísticos convencionales y machine learning entre tejido pulmonar sano y patológico de medidas de impedancia eléctrica. R Bragós Bardia, V Pajares Ruiz, A Rafecas, FJ Rosell Ferrer, ... CASEIB 2023: XLI Congreso Anual de la Sociedad Española de Ingeniería … , 2023 2023
Electrical Impedance Tomography to Measure Spirometry Parameters in Chronic Obstructive Pulmonary Disease Patients FM Vargas Luna, S Kashina, PJ Riu Costa, P Casan Claró, ... Revista mexicana de ingeniería biomédica 43 (3) , 2022 2022 Citations: 3
Effect of calibration for tissue differentiation between healthy and neoplasm lung using minimally invasive electrical impedance spectroscopy G Company-Se, L Nescolarde, V Pajares, A Torrego, PJ Riu, J Rosell, ... IEEE access 10, 103150-103163 , 2022 2022 Citations: 6
Minimally Invasive Lung Tissue Differentiation Using Electrical Impedance Spectroscopy L Nescolarde, V Pajares Ruiz, A Torrego, PJ Riu, J Rosell Ferrer, ... 2022
Effect of calibration for tissue differentiation between healthy and neoplasm lung using minimally invasive electrical impedance spectroscopy N Selva, L Digna, V Pajares Ruiz, A Torrego Fernández, PJ Riu Costa, ... 2022
Using temporal electrical impedance spectroscopy measures to differentiate lung pathologies with the 3-electrode method LD Nescolarde Selva, FJ Rosell Ferrer, PJ Riu Costa, V Pajares Ruiz, ... ICBEM-ICEBI-EIT, 327-330 , 2022 2022
Minimally invasive lung tissue differentiation using electrical impedance spectroscopy: A comparison of the 3-and 4-electrode methods G Company-Se, L Nescolarde, V Pajares, A Torrego, PJ Riu, J Rosell, ... IEEE access 10, 7354-7367 , 2021 2021 Citations: 8
Minimally invasive real-time electrical impedance spectroscopy diagnostic tool for lung parenchyma pathologies PJ Riu, G Company, R Bragós, J Rosell, V Pajares, A Torrego 2020 42nd Annual International Conference of the IEEE Engineering in … , 2020 2020 Citations: 6
Electrical impedance signal analysis for medical diagnosis FM Vargas Luna, M Balleza-Ordaz, MR Huerta Franco, P Riu Bioimpedance in Biomedical Applications and Research, 65-85 , 2018 2018 Citations: 4
MOST CITED SCHOLAR PUBLICATIONS
Skin impedance from 1 Hz to 1 MHz J Rosell, J Colominas, P Riu, R Pallas-Areny, JG Webster IEEE Transactions on Biomedical Engineering 35 (8), 649-651 , 2002 2002 Citations: 509
In Vivo and In Situ Ischemic Tissue Characterization Using Electrical Impedance Spectroscopy a O Casas, R Bragos, PJ Riu, J Rosell, M Tresanchez, M Warren, ... Annals of the New York Academy of Sciences 873 (1), 51-58 , 1999 1999 Citations: 150
Heating of tissues by microwaves: A model analysis KR Foster, A Lozano‐Nieto, PJ Riu, TS Ely Bioelectromagnetics: Journal of the Bioelectromagnetics Society, The Society … , 1998 1998 Citations: 126
A wide-band AC-coupled current source for electrical impedance tomography R Bragos, J Rosell, P Riu Physiological measurement 15 (2A), A91-A99 , 1994 1994 Citations: 111
A thermal model for human thresholds of microwave‐evoked warmth sensations PJ Riu, KR Foster, DW Blick, ER Adair Bioelectromagnetics: Journal of the Bioelectromagnetics Society, The Society … , 1997 1997 Citations: 104
On-line monitoring of yeast cell growth by impedance spectroscopy A Soley, M Lecina, X Gámez, JJ Cairo, P Riu, X Rosell, R Bragos, F Godia Journal of biotechnology 118 (4), 398-405 , 2005 2005 Citations: 103
Heating of tissue by near-field exposure to a dipole: a model analysis PJ Riu, KR Foster IEEE transactions on biomedical engineering 46 (8), 911-917 , 1999 1999 Citations: 92
Multi-frequency static imaging in electrical impedance tomography: Part 1 instrumentation requirements PJ Riu, J Rosell, A Lozano, R Pallà-Areny Medical and Biological Engineering and Computing 33 (6), 784-792 , 1995 1995 Citations: 76
Sensitivity maps for low-contrast perturbations within conducting background in magnetic induction tomography H Scharfetter, P Riu, M Populo, J Rosell Physiological measurement 23 (1), 195-202 , 2002 2002 Citations: 74
In vivo electrical bioimpedance characterization of human lung tissue during the bronchoscopy procedure. A feasibility study B Sanchez, G Vandersteen, I Martin, D Castillo, A Torrego, PJ Riu, ... Medical Engineering & Physics 35 (7), 949-957 , 2013 2013 Citations: 71
Common-mode feedback in electrical impedance tomography J Rosell, P Riu Clinical Physics and Physiological Measurement 13 (A), 11-14 , 1992 1992 Citations: 67
Electrical bioimpedance methods: applications to medicine and biotechnology PJ Rui, J Rosell, R Bragós, Ó Casas (No Title) , 1999 1999 Citations: 66
Use of electrical impedance tomography (EIT) for the assessment of unilateral pulmonary function RE Serrano, B De Lema, O Casas, T Feixas, N Calaf, V Camacho, I Carrió, ... Physiological measurement 23 (1), 211-220 , 2002 2002 Citations: 65
Green hams electrical impedance spectroscopy (EIS) measures and pastiness prediction of dry cured hams L Guerrero, I Gobantes, MÀ Oliver, J Arnau, MD Guàrdia, J Elvira, P Riu, ... Meat Science 66 (2), 289-294 , 2004 2004 Citations: 60
A parallel broadband real-time system for electrical impedance tomography O Casas, J Rosell, R Bragós, A Lozano, PJ Riu Physiological measurement 17 (4A), A1-A6 , 1996 1996 Citations: 59
Initial analysis of SAR from a cell phone inside a vehicle by numerical computation G Anzaldi, F Silva, M Fernández, M Quílez, PJ Riu IEEE transactions on biomedical engineering 54 (5), 921-930 , 2007 2007 Citations: 58
A broadband system for multifrequency static imaging in electrical impedance tomography PJ Riu, J Rosell, A Lozano, R Pallàs-Areny Clinical Physics and Physiological Measurement 13 (A), 61-65 , 1992 1992 Citations: 57
Thermal diagnostics front-end electronics for LISA Pathfinder J Sanjuán, A Lobo, M Nofrarias, J Ramos-Castro, PJ Riu Review of Scientific Instruments 78 (10) , 2007 2007 Citations: 51
SIVA UAV: A case study for the EMC analysis of composite air vehicles MR Cabello, S Fernández, M Pous, E Pascual-Gil, LD Angulo, P López, ... IEEE Transactions on Electromagnetic Compatibility 59 (4), 1103-1113 , 2017 2017 Citations: 50
Evaluation of the electrical impedance spectroscopy (EIS) equipment for ham meat quality selection MÀ Oliver, I Gobantes, J Arnau, J Elvira, P Riu, N Grèbol, JM Monfort Meat science 58 (3), 305-312 , 2001 2001 Citations: 45