Pradeep Kumar
@iitbhu.ac.in
ASSOCIATE PROFESSOR, Department Of Chemical Engineering
Indian institute of technology banaras hindu university
EDUCATION
B.Tech, M.Tech, Ph.D (Chemical Engineering)
RESEARCH INTERESTS
Catalytic Thermal Treatment , Coagulation- Flocculation, Adsorption, Fenton Oxidation
Scopus Publications
Scopus Publications
Priyanka Yadav and Pradeep Kumar
Springer Science and Business Media LLC
Priyanka Yadav, Philips Kumar Rai, and Pradeep Kumar
Elsevier BV
Sanchit Ratra, Bhaskaranand Pant, Kapil Roy, Sunny Manohar, Pradeep Kumar, Sangeeta Singh, Kaniki Tumba, Kamlesh Kumari, and Prashant Singh
Elsevier BV
Chandrashekhar Singh, Sumit Kumar Anand, Richa Upadhyay, Nidhi Pandey, Pradeep Kumar, Deepjyoti Singh, Punit Tiwari, Rajesh Saini, Kavindra Nath Tiwari, Sunil Kumar Mishra,et al.
Elsevier BV
Amit Kumar and Pradeep Kumar
Royal Society of Chemistry (RSC)
We investigate the effect of water molecules (H2O and (H2O)2) on HOCl + Cl˙ → ClO˙ + HCl (R1), and HOCl + Cl˙ → OH˙ + Cl2 (R2) reactions, using quantum chemical and kinetics calculations.
Madhukar S. Said, Nilesh S. Khonde, Pradeep Kumar, and Jayant M. Gajbhiye
American Chemical Society (ACS)
Fluoroarene-mediated trifluoromethylation of carboxylic acids for the synthesis of trifluoromethyl ketones is disclosed. The fluoroarene activates the acid group and generates the fluoride source in situ for the trifluoromethylation reaction. The present protocol is safe and metal-free, operates under mild reaction conditions, and does not require any external additives to generate trifluoromethyl anion. The current transformation provides good functional group tolerance and also delivers 92% and 88% yields of trifluoromethyl ketones in batch and continuous flow, respectively.
Philips Kumar Rai and Pradeep Kumar
Royal Society of Chemistry (RSC)
In the present work, we have studied the HO2˙ + O3 → HO˙ + 2O2 reaction using chemical kinetics and quantum chemical calculations.
Smriti R Deka, Reena Singh, Pratiksha Verma, and Pradeep Kumar
Wiley
Chikanshi Sharma, Madhu Kamle, and Pradeep Kumar
Wiley
M. Singh, P. Kumar, N. S. Singh, and A. Jain
Rasayan Journal of Chemistry
In this proposed research work, Zinc oxide is fabricated with carbon nanotubes, nitrogen, and silver. The conclusion of the distinctive hybrid of dopants on the ZnO/MWCNT nanocomposite was studied. Acidic and basic nature dyes are used to check the efficiency of the composite photocatalyst. The hydrothermal & microwave route was adapted for combining mesoporous nanocomposite samples. The XRD analysis confirmed the information to the nanoscale crystal with the hexagonal dimension of ZnO. The observation of UV-vis spectra validates its photocatalytic competency in the visible beam as an outcome of the reduction in the bandgap energy. The proficiency of the photocatalyst was additionally entrenched over the axing in electron-hole recombination activity referring to dwindling PL intensity. The BET inspection supports the mesoporous structures of the samples. The SEM micrograph revealed the existence of agglomeration in nanoparticles with MWCNT while the perusal of TEM images established the existence of a 16–24 nm diameter of the MWCNT. Furthermore, the EDX analysis confirmed the presence of the Zn, N, O, Ag, and C.
Himashree Bora, Madhu Kamle, Hesham Hassan, Ahmed Al-Emam, Sidharth Chopra, Nikhil Kirtipal, Shiv Bharadwaj, and Pradeep Kumar
MDPI AG
A new Coronaviridae strain, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), emerged from Wuhan city of China and caused one of the substantial global health calamities in December 2019. Even though several vaccines and drugs have been developed worldwide since COVID-19, a cost-effective drug with the least side effects is still unavailable. Currently, plant-derived compounds are mostly preferred to develop antiviral therapeutics due to its less toxicity, easy access, and cost-effective characteristics. Therefore, in this study, 124 phytochemical compounds from plants of Lauraceae family with medicinal properties were virtually screened against SARS-CoV-2 Mpro. Identification of four phytomolecules, i.e., cassameridine, laetanine, litseferine and cassythicine, with docking scores −9.3, −8.8, −8.6, and −8.6 kcal/mol, respectively, were undertaken by virtual screening, and molecular docking. Furthermore, the molecular dynamic simulation and essential dynamics analysis have contributed in understanding the stability and inhibitory effect of these selected compounds. These phytomolecules can be considered for further in vitro and in vivo experimental study to develop anti-SARS-CoV-2 therapeutics targeting the main protease (Mpro).
Zeba Ahmadi, Diksha Jha, Hemant Kumar Gautam, Pradeep Kumar, and Ashwani Kumar Sharma
Elsevier BV
Nayanika Chakraborty, Diksha Jha, Indrajit Roy, Pradeep Kumar, Shailendra Singh Gaurav, Kalisvar Marimuthu, Oon-Tek Ng, Rajamani Lakshminarayanan, Navin Kumar Verma, and Hemant K. Gautam
Springer Science and Business Media LLC
AbstractGiven the spasmodic increment in antimicrobial resistance (AMR), world is on the verge of “post-antibiotic era”. It is anticipated that current SARS-CoV2 pandemic would worsen the situation in future, mainly due to the lack of new/next generation of antimicrobials. In this context, nanoscale materials with antimicrobial potential have a great promise to treat deadly pathogens. These functional materials are uniquely positioned to effectively interfere with the bacterial systems and augment biofilm penetration. Most importantly, the core substance, surface chemistry, shape, and size of nanomaterials define their efficacy while avoiding the development of AMR. Here, we review the mechanisms of AMR and emerging applications of nanoscale functional materials as an excellent substitute for conventional antibiotics. We discuss the potential, promises, challenges and prospects of nanobiotics to combat AMR. Graphical Abstract
Santosh Yadav, Reena Singh, and Pradeep Kumar
Wiley
Pradeep Kumar, Akansha Gupta, Dipendra Kumar Mahato, Shikha Pandhi, Arun Kumar Pandey, Raveena Kargwal, Sadhna Mishra, Rajat Suhag, Nitya Sharma, Vivek Saurabh,et al.
MDPI AG
Cereals and cereal-based products are primary sources of nutrition across the world. However, contamination of these foods with aflatoxins (AFs), secondary metabolites produced by several fungal species, has raised serious concerns. AF generation in innate substrates is influenced by several parameters, including the substrate type, fungus species, moisture content, minerals, humidity, temperature, and physical injury to the kernels. Consumption of AF-contaminated cereals and cereal-based products can lead to both acute and chronic health issues related to physical and mental maturity, reproduction, and the nervous system. Therefore, the precise detection methods, detoxification, and management strategies of AFs in cereal and cereal-based products are crucial for food safety as well as consumer health. Hence, this review provides a brief overview of the occurrence, chemical characteristics, biosynthetic processes, health hazards, and detection techniques of AFs, along with a focus on detoxification and management strategies that could be implemented for food safety and security.
Vishva Jeet Anand, Amit Kumar, and Pradeep Kumar
Elsevier BV
H. Jena, Z. Ahmadi, P. Kumar, and G. Dhawan
Elsevier BV
Reena Singh, Diksha Jha, Uma Dhawan, Hemant K. Gautam, and Pradeep Kumar
Springer Science and Business Media LLC
Pradeep Kumar, Dipendra Kumar Mahato, Akansha Gupta, Surabhi Pandey, Veena Paul, Vivek Saurabh, Arun Kumar Pandey, Raman Selvakumar, Sreejani Barua, Mandira Kapri,et al.
MDPI AG
Mycotoxins are secondary metabolites produced by fungi that infect a wide range of foods worldwide. Nivalenol (NIV), a type B trichothecene produced by numerous Fusarium species, has the ability to infect a variety of foods both in the field and during post-harvest handling and management. NIV is frequently found in cereal and cereal-based goods, and its strong cytotoxicity poses major concerns for both human and animal health. To address these issues, this review briefly overviews the sources, occurrence, chemistry and biosynthesis of NIV. Additionally, a brief overview of several sophisticated detection and management techniques is included, along with the implications of processing and environmental factors on the formation of NIV. This review’s main goal is to offer trustworthy and current information on NIV as a mycotoxin concern in foods, with potential mitigation measures to assure food safety and security.
Amit Kumar and Pradeep Kumar
Royal Society of Chemistry (RSC)
In the present work, we have estimated the gas-phase acidity of different water clusters, i.e., (H2O)n, n = 1–20, 30, 35, 42, 54, 80, and 100.
Santosh Yadav, Diksha Jha, Hemant K. Gautam, and Pradeep Kumar
Springer Science and Business Media LLC
Philips Kumar Rai, Saptarshi Sarkar, Biman Bandyopadhyay, and Pradeep Kumar
Royal Society of Chemistry (RSC)
In the present work, we have studied the oxidation of HOSO˙ by O2 (3Σg−) molecules employing quantum chemical and kinetic calculations.
Madhu Kamle, Dipendra Kumar Mahato, Akansha Gupta, Shikha Pandhi, Bharti Sharma, Kajal Dhawan, Vasundhara, Sadhna Mishra, Manoj Kumar, Abhishek Dutt Tripathi,et al.
MDPI AG
Mycotoxins are fungi-produced secondary metabolites that can contaminate many foods eaten by humans and animals. Deoxynivalenol (DON), which is formed by Fusarium, is one of the most common occurring predominantly in cereal grains and thus poses a significant health risk. When DON is ingested, it can cause both acute and chronic toxicity. Acute signs include abdominal pain, anorexia, diarrhea, increased salivation, vomiting, and malaise. The most common effects of chronic DON exposure include changes in dietary efficacy, weight loss, and anorexia. This review provides a succinct overview of various sources, biosynthetic mechanisms, and genes governing DON production, along with its consequences on human and animal health. It also covers the effect of environmental factors on its production with potential detection, management, and control strategies.
Diksha Jha, Prasanna Kumar Thiruveedula, Rajiv Pathak, Bipul Kumar, Hemant K. Gautam, Shrish Agnihotri, Ashwani Kumar Sharma, and Pradeep Kumar
Elsevier BV