@kussc.ac. in
Assistant Professor and Dept. of Chemistry
Kuvempu University, Sahyadri Science College, SHIVAMOGGA
M. Sc., M. Phil., & Ph. D degrees from Gulbrga University, Gulbarga. Presently working as s assistant Professor and PG coordinator, Dept. of PG studies in Chemistry, kuvempu University, Sahyadri Science College, SHIVAMOGGA, karnataka, india
M. Sc., M. Phil., Ph. D.
Multidisciplinary, General Chemistry, Organic Chemistry, Spectroscopy
Scopus Publications
K.R. Sumadevi, G. Krishnamurthy, H.S. Bhojya Naik, Prabhaker Walmik, Malathesh Pari, N. Ranjitha, R.S. Priya Rani, and P. Parameshwara Naik
Asian Journal of Chemistry
Poly(vinyl pyrrolidone) capped and uncapped Co:ZnS nanoparticles have been synthesized by co-precipitation method. These synthesized nanoparticles were characterized using spectral techniques and the optical and photoluminescence properties of nanoparticles were also studied. Poly(vinyl pyrrolidone) capped nanoparticles has been studied for the electrochemical sensing of various biomolecules. The Co:ZnS modified glassy carbon electrode (GCE) proved to be effective nanoparticles composite electrode to detect biomolecules electrochemically with a wide linear detection range of 0.2 to 1.6 μmol/L, Also a low detection limit (LOD) of 0.06 μM/L and excellent sensitivity of 4.366 μA μM-1 has been obtained. It is observed that the particle size of nanoparticles is affected by the capping agent. It is therefore the modified electrode has become a good electrode material with a greater stability without leaching. The optical band gap was determined by UV-visible spectra and the value is found to be in the range of 3.75 to 4.00 eV. The photocatlytic activity on Eriochrome black T dye in the visible region using nanoparticles has been determined. It was found that the capped nanoparticles are more effective in photocatalytic degradation due to low energy consumption and safe recovery of it after catalytic performance from polluted water.
K. R. Sumadevi, G. Krishnamurthy, Prabhaker Walmik, R. S. Priya Rani, Satish Naik, H. S. Bhojya Naik, and Nagaraja Naik
Springer Science and Business Media LLC
K. S. Jithendra Kumara, G. Krishnamurthy, Prabhaker Walmik, Satish Naik, R. S. Priya Rani, and Nagargaja Naik
Springer Science and Business Media LLC
G. Arun Kumar, H. S. Bhojya Naik, R. Viswanath, G. Krishnamurthy, and Prabhaker Walmik
Springer Science and Business Media LLC
Prabhakar Walmik, Basavaraj S Naraboli, Swathi B, and Somashekhar Ghanti
Innovare Academic Sciences Pvt Ltd
Objective: The present study envisage a novel series of thiazole, indole and thiazolidine derivatives, namely, N-((5-Substituted-2-phenyl-1 H-indol-3-yl)methylene)-4,5,6,7-tetrahydro-5,7,-dimethylbenzo [d]thiazole-2-amine (4a-c), 2-(5-substituted-2-phenyl-1H-indol-3-yl)-3-(4,5,6,7- trimethylbenzo[d]thiazol-2-yl)-thiazolidin-4-one (5a-c) and 5-benzylidine-2-(5-substituted-2phenyl-1H-indol-3yl)-3-(4,5,6,7-tetrahydro-5,5,7- trimethylbenzo[d]thiazol-2-yl) thiazolidin-4-one (6a-c).Methods: All the newly synthesized compounds were characterized by infrared, 1H, 13C nuclear magnetic resonance and mass spectral data and elemental analysis and evaluated for in vitro antimicrobial activity.Results: Novel compounds N-((5-Substituted-2-phenyl-1H-indol-3-yl)methylene)-4,5,6,7-tetrahydro-5,7,-dimethylbenzo [d]thiazole-2-amine (4a-c), 2-(5-substituted-2-phenyl-1H-indol-3-yl)-3-(4,5,6,7-trimethylbenzo[d]thiazol-2-yl)-thiazolidin-4-one (5a-c) and 5-benzylidine-2-(5-substituted- 2phenyl-1H-indol-3yl)-3-(4,5,6,7-tetrahydro-5,5,7-trimethyl benzo[d]thiazol-2-yl)thiazolidin-4-one (6a-c) have been made and characterized using spectral and analytical data. The results of antibacterial and antifungal activities showed that some of the synthesized compounds exhibited promising activities.Conclusion: All the newly synthesized compounds were carried out by the broth microdilution method (NCCLS. 2002) in a DMF concentration of 500, 250, 125, and 62.5 μg/ml. Gentamycin and fluconazole are used as reference standards for antibacterial and antifungal activity, respectively. The final results revealed that compounds 4b, 5b, and 6b exhibited potent antimicrobial activity when compared to the standard drugs.
Anand R. Saundane, Prabhaker Walmik, Manjunatha Yarlakatti, Vijaykumar Katkar, and Vaijinath A. Verma
Wiley
The key intermediate 6‐amino‐3‐methyl‐4‐aryl‐1‐(5′‐substituted‐3′‐phenyl‐1H‐indol‐2′‐carbonyl)‐1,4‐dihydropyrano[2,3‐c]pyrazol‐5‐carbonitriles 3a, 3b, 3c, 3d, 3e, 3f, 3g, 3h, 3i, 3j, 3k, 3l, 3m, 3n, 3o were prepared by cyclocondensation of 3‐methyl‐1‐(5′‐substituted‐3′‐phenyl‐1H‐indol‐2′‐carbonyl)‐5‐(4H)‐pyrazolones 1a, 1b, 1c with arylidine derivatives of malononitrile 2a, 2b, 2c, 2d, 2e. The compounds 3a, 3b, 3c, 3d, 3e, 3f, 3g, 3h, 3i, 3j, 3k, 3l, 3m, 3n, 3o were subjected to cyclocondensation reaction with formamide, formic acid, and carbon disulfide to afford the title compounds 4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i, 4j, 4k, 4l, 4m, 4n, 4o, 5a, 5b, 5c, 5d, 5e, 5f, 5g, 5h, 5i, 5j, 5k, 5l, 5m, 5n, 5o, and 6a, 6b, 6c, 6d, 6e, 6f, 6g, 6h, 6i, 6j, 6k, 6l, 6m, 6n, 6o, respectively. The structures of all these previously unknown compounds were confirmed by their spectral studies and elemental analysis. These compounds were screened for their antimicrobial and antioxidant activities.
Anand R. Saundane, Katkar Vijaykumar, A. V. Vaijinath, and Prabhaker Walmik
Springer Science and Business Media LLC
A. R. Saundane and Prabhaker Walmik
Wiley
2‐N‐(2‐Phenyl‐1H‐indol‐3‐yl)imino‐4‐arylthiazoles (3a–c) were used as key synthons for the preparation of (4‐arylthiazol‐2‐yl)‐4‐(2‐phenyl‐1H‐indol‐3‐yl)azetidin‐2‐ones (4a–c) and 3‐(4‐arylthiazol‐2‐yl)‐2‐(2‐phenyl‐1H‐indol‐3‐yl)thiazolidin‐4‐ones (5a–c). These newly synthesized compounds have been characterized with the help of IR, 1H NMR, 13C NMR, and mass spectral studies. All compounds were screened for their antioxidant, antimicrobial, antimycobacterial, and cytotoxic activities. Some of the compounds displayed excellent activity.
ANAND RAGHUNATH SAUNDANE, MANJUNATHA YARLAKATTI, PRABHAKER WALMIK, and VIJAYKUMAR KATKARf
Springer Science and Business Media LLC