Prabhurajeshwar

@davangereuniversity.ac.in

Assistant Professor, Department of Studies in Biotechnology Davangere University Davangere Karnataka India
Dr. Prabhurajeshwar

Prabhurajeshwar


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https://researchid.co/prabhuraj

RESEARCH, TEACHING, or OTHER INTERESTS

Biotechnology, Microbiology (medical), Microbiology, Agricultural and Biological Sciences
6

Scopus Publications

912

Scholar Citations

12

Scholar h-index

14

Scholar i10-index

Scopus Publications

  • Microbial metallonanoparticles—an alternative to traditional nanoparticle synthesis
    D. Srividya, J. Patel Seema, Prabhurajeshwar, H.M. Navya
    Environmental Applications of Microbial Nanotechnology Emerging Trends in Environmental Remediation, 2022
  • Application of molecular docking and dynamics tools in SARS-CoV-2 drug design: ligand-protein interaction studies
    Chandrashekar Srinivasa, Chandan Shivamallu, Sharadadevi Kallimani, P. Sushma, Shiva Prasad Kollur, Prabhurajeshwar, S.M. Gopinath
    Coronavirus Drug Discovery Druggable Targets and in Silico Update Volume 3, 2022
  • Potential probiotic Lactobacillus casei KLSA22 producing Lactase for Lactose Intolerant with an antibiotic susceptibility pattern
    Research Journal of Biotechnology, 2021
  • Seed-Phytopriming with Decalepis hamiltonii Extracts Improves Plant Health by Suppressing Aspergillus flavus Infection in Groundnut
    H.M. Navya, J. Naveen, P. Hariprasad, G. Hithamani, Prabhurajeshwar, S.R. Niranjana
    Journal of Biologically Active Products from Nature, 2021
    Aqueous and solvent extracts of Decalepis hamiltonii were selected among the sixteen plants based on their antagonistic activity against Aspergillus flavus. Among seven extracts of D. hamiltonii studied, butanol extract offered maximum percent of growth inhibition against A. flavus. Crude butanolic extract of D. hamiltonii recorded a minimum inhibitory concentration of 14 mg/ml. Similarly, seeds primed with different concentrations of butanol extract revealed that beyond 6 mg/ml the extracts were inhibitory to seed germination and seedling growth. But the concentration of 6 mg/ml also significantly suppressed the seed-borne incidence of A. flavus and improved seed quality variables in different cultivars of Groundnut. Phytochemical analysis of crude extract showed the presence of saponins and phenolics. The antifungal compound present in crude butanol extract was identified and characterized. The purified antifungal compound showed Rf value of 0.36 on TLC when acetate:toluene:chloroform:acetic acid (2:6:5:2 v/v) was as mobile phase. Further, characterization of pure compound following UV-visible spectra, IR-spectra, 1H-NMR, 13C-NMR, and LC-MS analysis revealed the compound as 2-hydroxy-4-methoxybenzaldehyde, which is a phenolic aldehyde.
  • Medicinal Potentials of Phytochemicals for the Management of Rabies
    D. Chandan, Shiva Prasad Kollur, Shashanka K. Prasad, Chandrashekar Srinivasa, Prabhurajeshwar, S. M. Gopinath, Chukwuebuka Egbuna, Chandan Shivamallu
    Neglected Tropical Diseases and Phytochemicals in Drug Discovery, 2021
    Among diseases of viral origin, rabies is considered a serious public health threat across the globe. It is estimated that around 55 000 peoples die of rabies every year, out of which the highest number of deaths are from Asia and African countries, making interests for the development of new drugs a non-priority for the developed nations, hence best classified as a neglected tropical disease. This chapter presents a short review of rabies, the epidemiology, morphology, and the potentials of medicinal plants against rabies virus.
  • Phytochemical analysis and antimicrobial activity of leaf and stem of ipomoea staphylina roem. & schult.
    Niranjan M H, Prabhurajeshwar
    International Journal of Research in Pharmaceutical Sciences, 2020
    Ipomoea staphylina Roem. & Schult.A plant belonging to Convolvulaceae is commonly found on hedges and bushes in the forests and wastelands. It is a perennial, woody and glabrous shrub with pink flowers. Traditionally Ipomoea staphylina is used for respiratory disorders. Traditionally genus Ipomoea is used as purgative, dyspepsia, anthelmintic, bronchitis. Medicinal plants are the primary sources of medicines in Ayurvedha, Siddha, and Folk medicine systems. In India, about 95% of all modern drugs are derived from medicinal plants and very likely most of these medicines are used by people to cure many ailments. The Ayurvedic literature Sarangdhar Samhita" highlighted the concept of polyherbalism to achieve greater therapeutic efficacy. The active phytochemical constituents of individual plants are insufficient to meet the desirable therapeutic effects.When combining the multiple herbs in a particular ratio, it will give a better therapeutic effect and reduce the toxicity. Most of them are active even at a low dose and safe at a high dose. Thus they have superior risk to benefit ratio. Based on this the present study deals with physicochemical, phytochemical studies such as and biochemical estimation of medicinal plant of a combined mixture of polyherbal Ipomoea staphylina., also study evaluates the ethanol and methanol extracts of leaf and stem for their preliminary phytochemical analysis, antibacterial and antifungal activity. In the study of the phytochemical analysis reveals the presence of carbohydrate, protein, flavonoids, glycosides, alkaloids. The Ipomoea staphylina of ethanolic leaf and stem extract showed potent antimicrobial activity in all the tested concentrations against E.coli, Staphylococcus aureus, Bacillus subtilis and Aspergillus niger.Ipomoea staphylina could be exploited as a valuable source of antibacterial agent enriching with known antimicrobial compounds. Further studies needed for future drug development to treat various infectious diseases by microbes.

RECENT SCHOLAR PUBLICATIONS

  • Harnessing the Pharmacological Activities (In vitro and insilico) of Schefflera venulosa and Identification of PotentPhytocompounds Using GC-MS
    PC Navya H.M , Varun S, Nagesh Gunavanthrao Yernale
    JOURNAL OF HERBS, SPICES & MEDICINAL PLANTS, 1-25 , 2025
    2025
  • Harnessing the therapeutic potential of macromolecular metal (II) complexes derived from quinoline and thiazole core ligands: synthesis, spectral analysis, in vitro and in …
    HMN Nagesh Gunavanthrao Yernale a,* , Basavarajaiah Suliphuldevara Mathada b ...
    Journal of Molecular Structure 1338, 1-16 , 2025
    2025
    Citations: 16
  • Eco-friendly synthesis of iron oxide nanoparticles (IO–NPs) from aqueous extract of Cissus quadrangularis L. (Veld grape): Characterization and pharmaceutical evaluation
    EIONPCLVC evaluation
    Journal of Molecular Structure 1332 , 2025
    2025
    Citations: 18
  • Phytochemical screening and green synthesis of silver nanoparticles from cinnamomum verum crude bark extract: evaluation of cell cytotoxicity and wound healing activity by in …
    GRMBSPGNNDS B.H
    International Journal of Advance and Applied Research 5 (42), 69-81 , 2024
    2024
  • Microbiological Evaluation and Antibiotic Susceptibility Pattern of Bacterial Isolates Associated with Some Contaminated Edible Fruits and Vegetables.
    M Gundappa, C Prabhurajeshwar, S Ahmed, HM Navya, M Vijayasarathy, ...
    Indian Journal of Agricultural Research 58 (2) , 2024
    2024
    Citations: 8
  • Exploring inhibitory potential of α–Glucosidase and α–Amylase activity and cytotoxic effect of Glycyrrhiza glabra traditionally used in Ayurveda for Diabetes management
    P Navya H M , Shwetha Huragi , Tathagath Waghmare, Mahadevi Narasanagi ...
    African Journal of Biological Sciences 6 (5), 6150-6165 , 2024
    2024
  • Isolation and Molecular Characterization of probiotics bacteria from fermented products
    X Li
    Journal of Applied Health Sciences and Medicine 2 (1), 8-14 , 2022
    2022
  • Actinobacteria: ecology, diversity, classification and extensive applications
    JS Yaradoddi, MH Kontro, SV Ganachari
    Springer Nature , 2022
    2022
    Citations: 8
  • Screening of Novel Metabolites from Actinobacteria
    Prabhurajeshwar, HM Navya, J Uppin, SJ Patel, C Kelmani
    Actinobacteria: Ecology, Diversity, Classification and Extensive … , 2022
    2022
  • Applications of metal and metal oxide-based nanomaterials in medical and biological activities
    C Ashajyothi, HK Handral, C Prabhurajeshwar
    Handbook of Research on Green Synthesis and Applications of Nanomaterials … , 2022
    2022
    Citations: 3
  • A Study on Seroprevalence among Clinically Suspected Dengue Viral Infection using IgM Antibody Capture ELISA for the Early Diagnosis
    C Prabhurajeshwar
    BR Nahata Smriti Sansthan International Journal of Phramaceutical Sciences … , 2021
    2021
  • Isolation, Identification and Analysis of Probiotic Characteristics of Lactobacillus spp. from Regional Yoghurts from Surendranagar District, Gujarat.
    M Soni, HR Shah, SM Patel
    Asian Journal of Dairy & Food Research 40 (3) , 2021
    2021
    Citations: 10
  • Cytotoxicity and genotoxicity of metal oxide nanoparticles in human pluripotent stem cell-derived fibroblasts
    HK Handral, C Ashajyothi, G Sriram, CR Kelmani, N Dubey, T Cao
    Coatings 11 (1), 107 , 2021
    2021
    Citations: 20
  • Seed-Phytopriming with Decalepis hamiltonii Extracts Improves Plant Health by Suppressing Aspergillus flavus Infection in Groundnut
    HM Navya, J Naveen, P Hariprasad, G Hithamani, Prabhurajeshwar, ...
    Journal of Biologically Active Products from Nature 11 (1), 70-81 , 2021
    2021
    Citations: 1
  • Chapter-1 Bio-Production of Biodiesel using Different Strains of Microorganisms
    MR Basutkar, HM Navya
    Natural Resource Management and Environmental Security 17, 1 , 2021
    2021
  • Screening of Novel Metabolites from Actinobacteria
    HM Prabhurajeshwar, J Uppin, SJ Patel, C Kelmani
    Actinobacteria: Ecology, Diversity, Classification and Extensive … , 2021
    2021
  • Phytochemical analysis and antimicrobial activity of Alternanthera paronychioides A. St.-Hil.-A smooth Joyweed
    MH Niranjan, C Prabhurajeshwar
    Asian Journal of Pharmacy and Pharmacology 7 (4), 156-164 , 2021
    2021
    Citations: 2
  • In vitro screening of potential probiotic lactic acid bacteria isolated from intestinal contents and gills of Nile tilapia
    N Prachom, K Rumjuankiat, A Sanguankiat, S Boonyoung, K Pilasombut
    International Journal of Agricultural Technology 16 (4), 937-948 , 2020
    2020
    Citations: 7
  • PhytochemicalAnalysisandAntimicrobialactivityofleafandstemofIpomoeastaphylinaRoem.&Schult.
    P Niranjan M H
    INTERNATIONALJOURNALOFRESEARCHINPHARMACEUTICALSCIENCES 11 (3), 4705-4714 , 2020
    2020
    Citations: 3
  • Phytochemical Analysis and Antimicrobial Activity of Leaf and Stem Extracts of Priva cordifolia (L.f.) Druce
    P Niranjan M H
    European Journal of Medicinal Plants 31 (7), 42-53 , 2020
    2020

MOST CITED SCHOLAR PUBLICATIONS

  • Probiotic potential of Lactobacilli with antagonistic activity against pathogenic strains: An in vitro validation for the production of inhibitory substances
    RKC Chidre Prabhurajeshwar
    Biomedical Journal 10 (-), 1-14 , 2017
    2017
    Citations: 267
  • Evaluation of antimicrobial properties and their substances against pathogenic bacteria in-vitro by probiotic Lactobacilli strains isolated from commercial yog
    KC C. Prabhurajeshwar a
    Clinical Nutrition Experimental 23 (-), 97-115 , 2018
    2018
    Citations: 174
  • Antibiofilm activity of biogenic copper and zinc oxide nanoparticles-antimicrobials collegiate against multiple drug resistant bacteria: a nanoscale approach
    C Ashajyothi, KH Harish, N Dubey, RK Chandrakanth
    Journal of Nanostructure in Chemistry 6 (4), 329-341 , 2016
    2016
    Citations: 149
  • Investigation of antifungal and anti-mycelium activities using biogenic nanoparticles: An eco-friendly approach
    Ashajyothi C.a, Prabhurajeshwar C.a, Harish K. Handralb, Chandrakanth ...
    Environmental Nanotechnology, Monitoring & Management 5 (-), 6 , 2016
    2016
    Citations: 46
  • Potential Bactericidal Effect of Silver Nanoparticles Synthesised from Enterococcus Species
    PC Kelmani Chandrakanth R1*, Ashajyothi C1, Ajay Kumar Oli2
    ORIENTAL JOURNAL OF CHEMISTRY 30 (3), 09 , 2008
    2008
    Citations: 43
  • Hydrothermal assisted biosynthesis of silver nanoparticles from Streptomyces sp. GUT 21 (KU500633) and its therapeutic antimicrobial activity
    PPDCPKR Chandrakanth
    Journal of Nanostructure in chemistry 6 (3), 11 , 2016
    2016
    Citations: 28
  • Cytotoxicity and genotoxicity of metal oxide nanoparticles in human pluripotent stem cell-derived fibroblasts
    HK Handral, C Ashajyothi, G Sriram, CR Kelmani, N Dubey, T Cao
    Coatings 11 (1), 107 , 2021
    2021
    Citations: 20
  • Antibacterial activity of biogenic zinc oxide nanoparticals synthesised from Enterococcus faecalis
    C Ashajyothi, NR Manjunath, CR Kelmani
    Sphinx Knowledge House , 2014
    2014
    Citations: 19
  • Eco-friendly synthesis of iron oxide nanoparticles (IO–NPs) from aqueous extract of Cissus quadrangularis L. (Veld grape): Characterization and pharmaceutical evaluation
    EIONPCLVC evaluation
    Journal of Molecular Structure 1332 , 2025
    2025
    Citations: 18
  • Harnessing the therapeutic potential of macromolecular metal (II) complexes derived from quinoline and thiazole core ligands: synthesis, spectral analysis, in vitro and in …
    HMN Nagesh Gunavanthrao Yernale a,* , Basavarajaiah Suliphuldevara Mathada b ...
    Journal of Molecular Structure 1338, 1-16 , 2025
    2025
    Citations: 16
  • A pilot toxicology study of biogenic silver nanoparticles: in vivo by intraperitoneal and intravenous infusion routes in rats
    C Ashajyothi, R Kelmani Chandrakanth
    Journal of Experimental Nanoscience 14 (1), 89-106 , 2019
    2019
    Citations: 15
  • Biological synthesis and characterization of gold nanoparticles from Enterococcus faecalis
    C Ashajyothi, RK Chandrakanth
    Journal of bionanoscience 8 (4), 255-259 , 2014
    2014
    Citations: 14
  • An overview of bacteriophage therapy over antibiotics; as an alternative for controlling bacterial infections
    C Prabhurajeshwar, PP Desai, T Waghmare, SB Rashmi
    International Journal of Pharmaceutical Sciences and Research 11 (3), 993-1006 , 2020
    2020
    Citations: 11
  • Isolation, Identification and Analysis of Probiotic Characteristics of Lactobacillus spp. from Regional Yoghurts from Surendranagar District, Gujarat.
    M Soni, HR Shah, SM Patel
    Asian Journal of Dairy & Food Research 40 (3) , 2021
    2021
    Citations: 10
  • Microbiological Evaluation and Antibiotic Susceptibility Pattern of Bacterial Isolates Associated with Some Contaminated Edible Fruits and Vegetables.
    M Gundappa, C Prabhurajeshwar, S Ahmed, HM Navya, M Vijayasarathy, ...
    Indian Journal of Agricultural Research 58 (2) , 2024
    2024
    Citations: 8
  • Actinobacteria: ecology, diversity, classification and extensive applications
    JS Yaradoddi, MH Kontro, SV Ganachari
    Springer Nature , 2022
    2022
    Citations: 8
  • Shigellosis: A conformity review of the Microbiology, Pathogenesis and Epidemiology with consequence for Prevention and Management issues
    P Chandrakanth R
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY 12 (1), 406-417 , 2018
    2018
    Citations: 8
  • Prevalence and antibiotic susceptibility pattern of fluoroquinolone resistant Shigella species isolated from infants stool in Gulbarga district, Karnataka, India
    KCR Prabhurajeshwar*, Ajay kumar Oli, Ashajyothi C
    Asian Pacific Journal of Tropical Disease 5 (10.1016/S2222-1808(15)60871-4), 05 , 2015
    2015
    Citations: 8
  • In vitro screening of potential probiotic lactic acid bacteria isolated from intestinal contents and gills of Nile tilapia
    N Prachom, K Rumjuankiat, A Sanguankiat, S Boonyoung, K Pilasombut
    International Journal of Agricultural Technology 16 (4), 937-948 , 2020
    2020
    Citations: 7
  • DEVELOPMENT OF IN VITRO METHODOLOGIES FOR INHIBITION OF PATHOGENIC BACTERIA BY POTENTIAL PROBIOTIC LACTOBACILLUS SPS; AN EVIDENCE FOR PRODUCTION OF ANTIMICROBIAL SUBSTANCES
    KCR Prabhurajeshwar C.
    International Journal of Pharmacy and pharmaceutical sciences 8 (12), 10 , 2016
    2016
    Citations: 7