Dr. PRASHANTH T

Scopus Publications

Super capacitor, electrochemical measurement and sun light driven photocatalytic applications of CuFe2O4 NPs synthesized from bio-resource extract
Giridhar Meenakshi, B.C. Manjunath, S.C. Prashantha, T. Prashanth, B.S. Surendra
Sensors International, 2023
The CuFe 2 O 4 nanoparticle has been successfully synthesized from bio-mediated ( Aloe-Vera ) combustion process. The structural characterization of synthesized nanoparticle was achieved by spectral-characterizations viz; XRD, SEM, FT-IR and optical examinations. The XRD studies displays a spinel cubic phase development of nanoparticle and its average-particle size (19.3 nm). Low band gap energy of synthesized nanoparticle has been recorded to be 2.84 eV using UV–Visible absorption spectroscopy, which impacts to higher photodegradation efficiency. The potential photocatalytic activity of synthesized nanoparticle was examined using Malachite Green (MG) organic dye as a model, which is performed under specific quantities of stock solution (60 ppm) and obtained nanoparticle (50 mg). The photodegradation efficiency of synthesized material was evaluated for MG dye degradation achieved with 87.5% at 140 min under Sun-light. The excellent oxidation-reduction peak potentials were observed for synthesized spinel ferrite nanoparticle modified with carbon paste investigated by electrochemical analysis using 0.1 M KCl in the different scan rates 0.01–0.05 V/s. The charge-discharge studies of CuFe 2 O 4 -graphite electrode at current density (0.4 A/g) was discussed which is well correspondence to pseudo-capacitive behaviour. The synthesized NPs through bio-resources extract has become a potential new insight into multiple practical applications.
Synthesis, analgesic, anti-inflammatory, COX/5-LOX inhibition, ulcerogenic evaluation, and docking study of benzimidazole bearing indole and benzophenone analogs
Khadri M.J. Nagesh, T. Prashanth, Hussien Ahmed Khamees, Shaukath Ara Khanum
Journal of Molecular Structure, 2022
Synthesis, characterization, docking study and antimicrobial activity of 2-(4-benzoylphenoxy)-1-[2-(1-methyl-1H-indol-3-yl)methyl)-1H-benzo[d]imidazol-1-yl] ethanone derivatives
T. Prashanth, V. Lakshmi Ranganatha, Ramith Ramu, Subhankar P. Mandal, C. Mallikarjunaswamy, Shaukath Ara Khanum
Journal of the Iranian Chemical Society, 2021
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma
T. Prashanth, B.R. Vijay Avin, Prabhu Thirusangu, V. Lakshmi Ranganatha, B.T. Prabhakar, J.N. Narendra Sharath Chandra, Shaukath Ara Khanum
Biomedicine and Pharmacotherapy, 2019
C NMR and mass spectral analysis. The result indicates that, 7-methoxy-2-oxo-2H-chromene-3-carboxylic acid [4-(4-methoxy-phenyl)-thiazol-2-yl]-amide (13f) showed potent activity against EAC and DLA cells in MTT (15.3 μM), tryphan blue (15.6 μM) and LDH (14.2 μM) leak assay with 5-fluorouracil as a standard. Further, the anti-neoplastic effect of the compound 13f was verified against Ehrlich ascites tumour by BrdU incorporation, TUNEL, FACS and DNA fragmentation assays. Experimental data showed that compound 13f induces the apoptotic cell death by activating apoptotic factors such as caspase-8 &-3, CAD, Cleaved PARP, γ-H2AX and by degrading genomic DNA of cancer cells and thereby decreasing the ascitic tumour development in mice. Besides, compound 13f was also subjected for docking studies to approve the in vitro and in vivo studies. The data revealed that the compound 13f has very good interaction with caspase 3 protein by binding with amino acid Arg 207 through hydrogen bond.
3D energy framework of a benzophenone acidic dimer
S. Madan Kumar, Avinash K. Kudva, B.C. Manjunath, P. Naveen, T. Prashanth, Shaukath Ara Khanum, N.K. Lokanath, P. Nagendra
Chemical Data Collections, 2019
Synthesis and biological activity of 5‑bromo‑2-chloropyrimidin-4-amine derivatives
V. Lakshmi Ranganatha, T. Prashanth, H.B. Vasanth Patil, D.G. Bhadregowda, C. Mallikarjunaswamy
Chemical Data Collections, 2018
Anti-inflammatory and antioxidant activity of salicylic acid conjugated dihydropyrazoline analogues
Naveen Puttaswamy, Rekha N D, Lakshmi Ranganatha, Prashanth T, Shaukath Ara Khanum
Journal of Applied Pharmaceutical Science, 2018
Syntheses of substituted salicylic acid appended pyrazoline analogues (7a-j) via 1,3-dipolar cycloaddition were reported earlier. In the present investigation we have performed the anti-inflammatory activity by phospholipase A2 (PLA2) inhibition and in vitro antioxidant activity by 2,2-diphenyl-1-picrylhydrazyl, nitric oxide, hydroxyl radical scavenging assay and ferrous ion chelating assay wherein compounds 7d, 7h, 7i and 7j have shown maximum antiinflammatory activity. Further, compounds 7d, 7f and 7h were proved to be excellent free radical scavengers.
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation
Prabhu Thirusangu, V. Vigneshwaran, T. Prashanth, B. R. Vijay Avin, Vikas H. Malojirao, H. Rakesh, Shaukath Ara Khanum, Riaz Mahmood, B. T. Prabhakar
Angiogenesis, 2017
Hirshfeld Surface Analysis and Crystal Structure of [2-Bromo-4-(4-Fluoro-Benzoyl)-Phenoxy]-Acetic Acid Ethyl Ester
N. Latha Rani, T. Prashanth, M. A. Sridhar, V. Lakshmi Ranganatha, A. K. Shaukath
Molecular Crystals and Liquid Crystals, 2016
The title compound C17H14BrFO4 was synthesized using 3-Bromo-4-hydroxy-phenyl-(4-fluoro-phenyl)-methanone, ethyl chloroacetate, and anhydrous potassium carbonate. Its structure was established using elemental analysis, NMR, and single crystal X-ray diffraction techniques. The compound crystallizes in orthorhombic crystal system and space group Pbca. The cell parameters are a = 10.1444(13) Å, b = 8.2781(10) Å, c = 38.423(5) Å, Z = 8, V = 3226.6(7) Å3. The dihedral angle between two least squares planes of two phenyl rings bridged by keto carbonyl group is −28.2(5)°. The molecule exhibits intermolecular interactions of the type C‒H…F and C‒H…O. The intercontacts in the crystal structure are studied using Hirshfeld surface analysis.
Synthesis, characterization, and antibacterial activity of 6-Chloro-8-methyl-2-oxo-2H-chromene-3-carboxylic acid ethyl ester
N. Latha Rani, T. Prashanth, M. A. Sridhar, H. D. Gurupadaswamy, K. Shaukath Ara, N. K. Lokanath
Molecular Crystals and Liquid Crystals, 2016
The title compound was synthesized by reacting 2-hydroxy-4-methoxy-benzaldehyde with diethyl malonate in the presence of piperidine catalyst and ethanol as solvent. The chemical structure of the title compound was elucidated by elemental analysis, 1H-NMR, and IR. The crystal structure was determined by X-ray diffraction data. It crystallizes in monoclinic crystal system, P21/c space group with unit cell parameters, a = 12.840(2) Å, b = 24.790(4) Å, c = 7.8544(13) Å, β = 98.035(5)°, V = 2475.5(7) Å3, and Z = 8. The molecular and crystal structure of the title compound is stabilized by inter- and intramolecular interactions of the type C—H···O. The newly synthesized compound was screened for its antibacterial activity against two gram-positive and two gram-negative bacteria.
Synthesis, Characterization, and Antibacterial Activity of 7-Fluoro-2-oxo-2 H -chromene-3-carboxylic Acid Ethyl Ester
N. Latha Rani, T. Prashanth, M. A. Sridhar, V. Lakshmi Ranganatha, A. K. Shaukath, N. K. Lokanath
Molecular Crystals and Liquid Crystals, 2015
Crystal structure of 2,4,6-triisopropyl-2',5'-dimethoxybiphenyl
N. Sharma, T. Prashanth, V. Lakshmi Ranganatha, S. Ara Khanum, R. Kant, V. K. Gupta
Crystallography Reports, 2015
Synthesis and biological efficacy of novel piperazine analogues bearing quinoline and pyridine moieties
M. Al-Ghorbani, N. D. Rekha, V. Lakshmi Ranganatha, T. Prashanth, T. Veerabasappagowda, S. A. Khanum
Russian Journal of Bioorganic Chemistry, 2015
Synthesis and evaluation of novel benzophenone-thiazole derivatives as potent VEGF-A inhibitors
T. Prashanth, Prabhu Thirusangu, B.R. Vijay Avin, V. Lakshmi Ranganatha, B.T. Prabhakar, Shaukath Ara Khanum
European Journal of Medicinal Chemistry, 2014
Evaluation of benzophenone-N-ethyl morpholine ethers as antibacterial and antifungal activities
A. Bushra Begum, Noor Fatima Khanum, V. Lakshmi Ranganatha, T. Prashanth, Mohammed Al-Ghorbani, Shaukath Ara Khanum
Journal of Chemistry, 2014
Synthesis, antioxidant, and xanthine oxidase inhibitory activities of 5-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione derivatives
A. Bushra Begum, Muneera Begum, V. Lakshmi Ranganatha, T. Prashanth, Farhan Zameer, Raghavendra Hegdekatte, Shaukath Ara Khanum
Archiv Der Pharmazie, 2014
Synthesis and larvicidal properties of benzophenone comprise indole analogues against Culex quinquefasciatus
V. Lakshmi Ranganatha, A. Bushra Begum, T. Prashanth, H.D. Gurupadaswamy, S.K. Madhu, S. Shivakumar, Shaukath Ara Khanum
Drug Invention Today, 2013
Synthesis, angiopreventive activity, and in vivo tumor inhibition of novel benzophenone-benzimidazole analogs
V. Lakshmi Ranganatha, B.R. Vijay Avin, Prabhu Thirusangu, T. Prashanth, B.T. Prabhakar, Shaukath Ara Khanum
Life Sciences, 2013
(4-Hydroxy-3,5-dimethylphenyl)(phenyl)methanone
C. S. Dileep, T. Prashanth, S. Jeyaseelan, S. A. Khanum, M. A. Sridhar
Acta Crystallographica Section E Structure Reports Online, 2013
In vitro antibacterial and antifungal evaluation of some benzophenone analogues
Der Pharma Chemica, 2013
Antimicrobial evaluation of 2-azetidinonyl 5-(2-benzoyl-phenoxymethyl)-1, 3, 4-oxadiazole derivatives
Der Pharma Chemica, 2013
In vitro antioxidant potential study of triazole and thiadiazole analogues
Journal of Chemical and Pharmaceutical Research, 2013
Ethyl 2-[4-(2-chloro-benzo-yl)-2,6-di-methyl-phen-oxy]ethano-ate
T. Prashanth, V. Lakshmi Ranganatha, M. K. Usha, Shaukath Ara Khanum, D. Revannasiddaiah, Sumati Anthal, Rajni Kant, Vivek K. Gupta
Acta Crystallographica Section E Structure Reports Online, 2012

RECENT SCHOLAR PUBLICATIONS

Electrochemical sensitive detection of green-mediated Ag-CdFe 2 O 4 NPs against lithium ion with 4-hydroxyacetanilide and sunlight driven photocatalytic activity
BS Surendra, HN Sowmya, KN Harish, M Bhaskar, K T, P T, N Basavaraju, ...
Ionics 31 (6), 6409-6424 , 2025
2025
Citations: 12
Design, synthesis and characterization of 8-[(1H-benzo [d] imidazol-2-yl) methoxy] quinoline derivatives as antimicrobial agents
T Prashanth, V Lakshmi Ranganatha, M Al-Ghorbani, S Girish, ...
Discover Chemistry 2 (1), 19 , 2025
2025
Citations: 8
Influence of Zr on the Sun-light driven photocatalytic activity, electrochemical sensor, and microbial applications of CuFe 2 O 4 NPs
M Giridhar, M BC, G K, K T, C MV, S BS, P T, P SC, AM HC
Sensing Technology 2 (1), 2417721 , 2024
2024
Citations: 2
Super capacitor, electrochemical measurement and sun light driven photocatalytic applications of CuFe2O4 NPs synthesized from bio-resource extract
G Meenakshi, BC Manjunath, SC Prashantha, T Prashanth, BS Surendra
Sensors International 4, 100237 , 2023
2023
Citations: 29
Synthesis, analgesic, anti-inflammatory, COX/5-LOX inhibition, ulcerogenic evaluation, and docking study of benzimidazole bearing indole and benzophenone analogs
KMJ Nagesh, T Prashanth, HA Khamees, SA Khanum
Journal of Molecular Structure 1259, 132741 , 2022
2022
Citations: 33
Synthesis, characterization, docking study and antimicrobial activity of 2-(4-benzoylphenoxy)-1-[2-(1-methyl-1 H -indol-3-yl)methyl)-1 H -benzo[d]imidazol-1-yl …
T Prashanth, VL Ranganatha, R Ramu, SP Mandal, C Mallikarjunaswamy, ...
Journal of the Iranian Chemical Society 18 (10), 2741-2756 , 2021
2021
Citations: 15
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma
T Prashanth, BRV Avin, P Thirusangu, VL Ranganatha, BT Prabhakar, ...
Biomedicine & Pharmacotherapy 112, 108707 , 2019
2019
Citations: 54
3D energy framework of a benzophenone acidic dimer
SM Kumar, AK Kudva, BC Manjunath, P Naveen, T Prashanth, ...
Chemical Data Collections 19, 100168 , 2019
2019
Citations: 10
Synthesis and Characterization of Coumarin Analogs: Evaluation of Antimicrobial and Antioxidant Activities
SAK Prashanth T, Bushra Begum A, Noor Fatima Khanum
International Research Journal of Pharmacy 9 (3), 22-30 , 2018
2018
Synthesis and Biological Applications of (E)-N-Benzylidene-5-bromo-2- chloropyrimidin-4-amine Derivatives
HBVP C. Mallikarjunaswamy, V. Lakshmi Ranganatha, T. Prashanth
Asian Journal of Organic & Medicinal Chemistry 3 (1), 1-9 , 2018
2018
Anti-inflammatory and antioxidant activity of salicylic acid conjugated dihydropyrazoline analogues
SAK Naveen Puttaswamy, Rekha N D, Lakshmi Ranganatha V, Prashanth T
Journal of Applied Pharmaceutical Science 8 (2), 60-64 , 2018
2018
Citations: 7
Synthesis and biological activity of 5–bromo–2-chloropyrimidin-4-amine derivatives
CM V. Lakshmi Ranganatha, T. Prashanth, H.B. Vasanth Patil, D.G. Bhadregowda
Chemical Data Collections 13, 1-10 , 2018
2018
Citations: 1
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation
P Thirusangu, V Vigneshwaran, T Prashanth, BR Vijay Avin, VH Malojirao, ...
Angiogenesis 20 (1), 55-71 , 2017
2017
Citations: 55
Hirshfeld surface analysis and crystal structure of [2-Bromo-4-(4-fluoro-benzoyl)-phenoxy]-acetic acid ethyl ester
NL Rani, T Prashanth, MA Sridhar, VL Ranganatha, AK Shaukath
Molecular Crystals and Liquid Crystals 629 (1), 78-85 , 2016
2016
Citations: 1
Synthesis, characterization, and antibacterial activity of 6-Chloro-8-methyl-2-oxo-2H-chromene-3-carboxylic acid ethyl ester
N Latha Rani, T Prashanth, MA Sridhar, HD Gurupadaswamy, ...
Molecular Crystals and Liquid Crystals 624 (1), 262-270 , 2016
2016
Citations: 2
Structural Study and Antibacterial Activity of a Benzophenone Derivative: [2-Bromo-4-(2-chloro-benzoyl)-phenoxy]-acetic acid ethyl ester
SAK N. Latha Rani, T. Prashanth, Zabiulla, M.A Sridhar
Journal of Applicable Chemistry 5 (3), 628-636 , 2016
2016
Citations: 6
Synthesis, Characterization, and Antibacterial Activity of 7-Fluoro-2-oxo-2 H-chromene-3-carboxylic Acid Ethyl Ester
NL Rani, T Prashanth, MA Sridhar, VL Ranganatha, AK Shaukath, ...
Molecular Crystals and Liquid Crystals 623 (1), 265-274 , 2015
2015
Citations: 2
Crystal structure of 2, 4, 6-triisopropyl-2', 5'-dimethoxybiphenyl
N Sharma, T Prashanth, V Lakshmi Ranganatha, S Ara Khanum, R Kant, ...
Crystallography Reports 60 (7), 1116-1120 , 2015
2015
Citations: 1
Synthesis and biological efficacy of novel piperazine analogues bearing quinoline and pyridine moieties
M Al-Ghorbani, ND Rekha, V Lakshmi Ranganatha, T Prashanth, ...
Russian Journal of Bioorganic Chemistry 41 (5), 554-561 , 2015
2015
Citations: 13
Synthesis and evaluation of novel benzophenone-thiazole derivatives as potent VEGF-A inhibitors
T Prashanth, P Thirusangu, BRV Avin, VL Ranganatha, BT Prabhakar, ...
European journal of medicinal chemistry 87, 274-283 , 2014
2014
Citations: 55

MOST CITED SCHOLAR PUBLICATIONS

Synthesis, angiopreventive activity, and in vivo tumor inhibition of novel benzophenone–benzimidazole analogs
T Prashanth, VL Ranganatha, BRV Avin, P Thirusangu, BT Prabhakar, ...
Life sciences 93 (23), 904-911 , 2013
2013
Citations: 58
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation
P Thirusangu, V Vigneshwaran, T Prashanth, BR Vijay Avin, VH Malojirao, ...
Angiogenesis 20 (1), 55-71 , 2017
2017
Citations: 55
Synthesis and evaluation of novel benzophenone-thiazole derivatives as potent VEGF-A inhibitors
T Prashanth, P Thirusangu, BRV Avin, VL Ranganatha, BT Prabhakar, ...
European journal of medicinal chemistry 87, 274-283 , 2014
2014
Citations: 55
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma
T Prashanth, BRV Avin, P Thirusangu, VL Ranganatha, BT Prabhakar, ...
Biomedicine & Pharmacotherapy 112, 108707 , 2019
2019
Citations: 54
Synthesis, analgesic, anti-inflammatory, COX/5-LOX inhibition, ulcerogenic evaluation, and docking study of benzimidazole bearing indole and benzophenone analogs
KMJ Nagesh, T Prashanth, HA Khamees, SA Khanum
Journal of Molecular Structure 1259, 132741 , 2022
2022
Citations: 33
Super capacitor, electrochemical measurement and sun light driven photocatalytic applications of CuFe2O4 NPs synthesized from bio-resource extract
G Meenakshi, BC Manjunath, SC Prashantha, T Prashanth, BS Surendra
Sensors International 4, 100237 , 2023
2023
Citations: 29
Synthesis, Antioxidant, and Xanthine Oxidase Inhibitory Activities of 5‐[4‐[2‐(5‐E thyl‐2‐pyridinyl) ethoxy] phenyl] methyl]‐2, 4‐thiazolidinedione Derivatives
AB Begum, M Begum, VL Ranganatha, T Prashanth, F Zameer, ...
Archiv der Pharmazie 347 (4), 247-255 , 2014
2014
Citations: 22
Synthesis of (4-benzoyl-phenoxy)-acetic acid derivatives and their efficacy as antioxidant agents
T Prashanth, VL Ranganatha, P Naveen, HD Gurupadaswamy, ...
Free Radicals and Antioxidants 3, S50-S54 , 2013
2013
Citations: 17
Synthesis and larvicidal properties of benzophenone comprise indole analogues against Culex quinquefasciatus
SAK V. Lakshmi Ranganatha, T. Prashanth, A. Bushra Begum
Drug Invention Today 5, 275-280 , 2013
2013
Citations: 17
Synthesis, characterization, docking study and antimicrobial activity of 2-(4-benzoylphenoxy)-1-[2-(1-methyl-1 H -indol-3-yl)methyl)-1 H -benzo[d]imidazol-1-yl …
T Prashanth, VL Ranganatha, R Ramu, SP Mandal, C Mallikarjunaswamy, ...
Journal of the Iranian Chemical Society 18 (10), 2741-2756 , 2021
2021
Citations: 15
Synthesis and biological efficacy of novel piperazine analogues bearing quinoline and pyridine moieties
M Al-Ghorbani, ND Rekha, V Lakshmi Ranganatha, T Prashanth, ...
Russian Journal of Bioorganic Chemistry 41 (5), 554-561 , 2015
2015
Citations: 13
Electrochemical sensitive detection of green-mediated Ag-CdFe 2 O 4 NPs against lithium ion with 4-hydroxyacetanilide and sunlight driven photocatalytic activity
BS Surendra, HN Sowmya, KN Harish, M Bhaskar, K T, P T, N Basavaraju, ...
Ionics 31 (6), 6409-6424 , 2025
2025
Citations: 12
3D energy framework of a benzophenone acidic dimer
SM Kumar, AK Kudva, BC Manjunath, P Naveen, T Prashanth, ...
Chemical Data Collections 19, 100168 , 2019
2019
Citations: 10
Evaluation of Benzophenone‐N‐ethyl Morpholine Ethers as Antibacterial and Antifungal Activities
A Bushra Begum, NF Khanum, VL Ranganatha, T Prashanth, ...
Journal of Chemistry 2014 (1), 941074 , 2014
2014
Citations: 10
Design, synthesis and characterization of 8-[(1H-benzo [d] imidazol-2-yl) methoxy] quinoline derivatives as antimicrobial agents
T Prashanth, V Lakshmi Ranganatha, M Al-Ghorbani, S Girish, ...
Discover Chemistry 2 (1), 19 , 2025
2025
Citations: 8
In vitro antibacterial and antifungal evaluation of some benzophenone analogues
M Al-Ghorbani, V Lakshmi Ranganatha, T Prashanth, B Begum, ...
Der Pharma Chemica 5 (4), 269-273 , 2013
2013
Citations: 8
Anti-inflammatory and antioxidant activity of salicylic acid conjugated dihydropyrazoline analogues
SAK Naveen Puttaswamy, Rekha N D, Lakshmi Ranganatha V, Prashanth T
Journal of Applied Pharmaceutical Science 8 (2), 60-64 , 2018
2018
Citations: 7
In vitro antioxidant potential study of triazole and thiadiazole analogues
M Al-Ghorbani, VL Ranganatha, T Prashanth, AB Begum, P Naveen, ...
Journal of Chemical and Pharmaceutical Research 5 (7), 246-250 , 2013
2013
Citations: 7
Structural Study and Antibacterial Activity of a Benzophenone Derivative: [2-Bromo-4-(2-chloro-benzoyl)-phenoxy]-acetic acid ethyl ester
SAK N. Latha Rani, T. Prashanth, Zabiulla, M.A Sridhar
Journal of Applicable Chemistry 5 (3), 628-636 , 2016
2016
Citations: 6
Synthesis and Inhibition of Microbial Growth by Benzophenone Analogues-A Simplistic Approach
T Prashanth, P Naveen, AG Mohammed, MS Asha
Asian Journal of Biomedical and Pharmaceutical Sciences 4 (29), 55 , 2014
2014
Citations: 5

Dr. PRASHANTH T

RESEARCH, TEACHING, or OTHER INTERESTS

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS