Dr Prashant A Karni

Scopus Publications

Efficacy of Various Herbal Preparations Against Oral Candida: A Lab‑Based Study
Prashant A. Karni, Aparna Muraleedharan, Srikala Bhandary, Sheetal Mujoo, Anuj Paul Maini, and Mudita Chaturvedi
Medknow
ABSTRACT Aim: This research was done to analyze the effectiveness related to herbal chemicals in tackling candidiasis. Materials and Methods: Grounded and ethanol-extracted residues of plants like Avicennia marina, Fagonia indica, Portulaca oleracea, Lawsania inermis, Ziziphus spina, Asphodelus tenuifolius, and Salvadora persica were used in the study. The extract was used against candida species, after which the antibacterial as well as cytotoxicity toward the former were evaluated. Results: L. inermis and P. oleracea with minimal inhibitory concentration of approx. 10 cenmL had an increased activity against candida species. The preparations of these plants acted against Candida albicans during its stages related to pathogenesis during biofilm production. Superadded infections like in case of bacterial infections along with candida can be difficult to cure. On human RBCs, these plant preparations had no toxicity at their minimum inhibitory concentration level. Conclusion: We concluded that, as far as being anti-candida and acting against MDR bacterial infections, preparations of plants were effective as an alternative to allopathic drugs.

Unique, cost-effective and retentive removable prosthesis to rehabilitate long span Kennedy'S class I edentulism with custom attachment system: A case report
Raghunath Patil, Anandkumar G Patil, Abhijit P Patil, Anuradha V Pawar, Prashant Karni, and Sayali Mardolkar
Jaypee Brothers Medical Publishing
AIM This case report describes about a distinctive custom-made attachment on the abutment teeth to improve the retention and stability of the removable partial denture (RPD). It also throws light on the cost-effective method for altering the abutment teeth with the aid of the crowns and custom-made attachments. BACKGROUND Achieving retention in Kennedy's class I bilateral edentulism usually affects the abutment teeth's periodontal health and eventually the retention is compromised. Distal extension edentulism also affects patient's masticatory efficiency. The rehabilitation of a patient with the long span Kennedy's class I condition complicates the problem because of the unavailability of enough abutments to support the prosthesis. Conventional removable prosthesis with clasps and cantilever fixed partial prosthesis are not advisable in this situation for the same reason. CASE DESCRIPTION A case with Kennedy's class I modification 1 partially edentulous arch with 1st and 2nd molars missing along with central incisors was rehabilitated with an inexpensive custom attachment using die pin and sleeve for giving a fixed prosthesis on abutment teeth and removable prosthesis with missing teeth. CONCLUSION This technique has advantages of retention better than conventional RPDs, protection of abutment health by restoring it with crown, easy to place and remove and very cost-effective. CLINICAL SIGNIFICANCE The entire technique demands less skill compared to semi precision and precision attachments.