Durairaj Ragu Varman

Scopus Publications

Gut dysbiosis in neurodevelopmental disorders: linking microbiota signatures to cognitive rigidity in autism spectrum disorder
Bhagavathi Sundaram Sivamaruthi, Periyanaina Kesika, Chaiyavat Chaiyasut, Durairaj Ragu Varman
Frontiers in Microbiology, 2026
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterised not only by social-communication difficulties but also by restricted interests, stereotyped behaviours, and marked cognitive rigidity. Over the past decade, converging lines of evidence have implicated gut dysbiosis, an imbalance in intestinal microbial composition and function, as a potentially important modulator of these behavioural phenotypes via the microbiota-gut-brain axis. In this narrative review, we integrate preclinical and clinical data to examine how specific microbial signatures, metabolic pathways, and immune and synaptic mechanisms may contribute to inflexible cognition in ASD. The manuscript outlines the organisation of the microbiota gut-brain axis in neurodevelopment and summarises reproducible microbial alterations reported in ASD cohorts. We then discuss how microbial metabolites, including short-chain fatty acids and tryptophan-derived neuroactive molecules, as well as immune mediators and neurotransmitter precursors, converge on pathways regulating excitatory-inhibitory balance, synaptic plasticity, and corticostriatal circuit function. Evidence from germ-free, genetic, and environmental rodent models provides causal support for microbiota-dependent modulation of repetitive and rigid behaviours, whilst clinical studies reveal associations between dysbiosis, metabolomic profiles, gastrointestinal symptoms, and ASD severity. Finally, we consider the translational landscape of microbiota-targeted interventions, probiotics, prebiotics, dietary strategies, and faecal microbiota transplantation and highlight key methodological and ethical challenges for moving toward precision microbiome-based therapies. Taken together, current data support gut dysbiosis as both a mechanistic contributor and a tractable therapeutic target for cognitive rigidity in ASD.
Spontaneous Calcium Transients Recorded from Striatal Astrocytes in a Preclinical Model of Autism
Hugo Saavedra-Bonilla, Durairaj Ragu Varman, Daniel Reyes-Haro
Neurochemical Research, 2024
Autism spectrum disorder (ASD) is known as a group of neurodevelopmental conditions including stereotyped and repetitive behaviors, besides social and sensorimotor deficits. Anatomical and functional evidence indicates atypical maturation of the striatum. Astrocytes regulate the maturation and plasticity of synaptic circuits, and impaired calcium signaling is associated with repetitive behaviors and atypical social interaction. Spontaneous calcium transients (SCT) recorded in the striatal astrocytes of the rat were investigated in the preclinical model of ASD by prenatal exposure to valproic acid (VPA). Our results showed sensorimotor delay, augmented glial fibrillary acidic protein -a typical intermediate filament protein expressed by astrocytes- and diminished expression of GABAA-ρ3 through development, and increased frequency of SCT with a reduced latency that resulted in a diminished amplitude in the VPA model. The convulsant picrotoxin, a GABAA (γ-aminobutyric acid type A) receptor antagonist, reduced the frequency of SCT in both experimental groups but rescued this parameter to control levels in the preclinical ASD model. The amplitude and latency of SCT were decreased by picrotoxin in both experimental groups. Nipecotic acid, a GABA uptake inhibitor, reduced the mean amplitude only for the control group. Nevertheless, nipecotic acid increased the frequency but diminished the latency in both experimental groups. Thus, we conclude that striatal astrocytes exhibit SCT modulated by GABAA-mediated signaling, and prenatal exposure to VPA disturbs this tuning.
Prevalence of Cardiovascular Diseases in South Asians: Scrutinizing Traditional Risk Factors and Newly Recognized Risk Factors Sarcopenia and Osteopenia/Osteoporosis
Haripriya Kuchi Bhotla, Arun Meyyazhagan, Karthika Pushparaj, Manikantan Pappuswamy, Aditi Chaudhary, et al.
Current Problems in Cardiology, 2024
Striatal synaptic changes and behavior in adult mouse upon prenatal exposure to valproic acid
Adan Hernandez, Evangelina Delgado-González, Ragu Varman Durairaj, Daniel Reyes-Haro, Ataúlfo Martínez-Torres, et al.
Brain Research, 2023
Blunted Amphetamine-induced Reinforcing Behaviors and Transporter Downregulation in Knock-in Mice Carrying Alanine Mutations at Threonine-258 and Serine-259 of Norepinephrine Transporter
Durairaj Ragu Varman, Padmanabhan Mannangatti, Mark A. Subler, Jolene J. Windle, Sammanda Ramamoorthy, et al.
Journal of Molecular Neuroscience, 2022
Kappa Opioid Receptor Mediated Differential Regulation of Serotonin and Dopamine Transporters in Mood and Substance Use Disorder
Durairaj Ragu Varman, Lankupalle D. Jayanthi, Sammanda Ramamoorthy
Handbook of Experimental Pharmacology, 2022
Neurokinin-1 Antagonism Distinguishes the Role of Norepinephrine Transporter from Dopamine Transporter in Mediating Amphetamine Behaviors
Padmanabhan Mannangatti, Durairaj Ragu Varman, Sammanda Ramamoorthy, Lankupalle D. Jayanthi
Pharmacology, 2021
Background: Amphetamine (AMPH) and other psychostimulants act on the norepinephrine (NE) transporter (NET) and the dopamine (DA) transporter (DAT) and enhance NE and DA signaling. Both NET and DAT share anatomical and functional characteristics and are regulated similarly by psychostimulants and receptor-linked signaling pathways. We and others have demonstrated that NET and DAT are downregulated by AMPH and substance P/neurokinin-1 receptor (NK1R)-mediated protein kinase C pathway. Objectives: Since both NET and DAT are downregulated by AMPH and NK1R activation and share high sequence homology, the objective of the study was to determine the catecholamine transporter specificity in NK1R modulation of AMPH-induced behaviors. Methods: The effect of NK1R antagonism on AMPH-induced conditioned place preference (CPP) as well as AMPH-induced NET and DAT downregulation was examined using NET and DAT knockout mice (NET-KO and DAT-KO) along with their wild-type littermates. Results: Aprepitant (5 mg/kg i.p.) significantly attenuated AMPH (2 mg/kg i.p.)-induced CPP in the wild-type and DAT-KO but not in the NET-KO. Locomotor activity measured during the post-conditioning test (in the absence of AMPH) showed higher locomotor activity in DAT-KO compared to wild-type or NET-KO. However, the locomotor activity of all 3 genotypes remained unchanged following aprepitant. Additionally, in the ventral striatum of wild-type, the AMPH-induced downregulation of NET function and surface expression but not that of DAT was attenuated by aprepitant. Conclusions: The results from the current study demonstrate that aprepitant attenuates the expression of AMPH-induced CPP in DAT-KO mice but not in NET-KO mice suggesting a role for NK1R-mediated NET regulation in AMPH-induced behaviors.
Novelty-induced hyperactivity and suppressed cocaine induced locomotor activation in mice lacking threonine 53 phosphorylation of dopamine transporter
Durairaj Ragu Varman, Mark A. Subler, Jolene J. Windle, Lankupalle D. Jayanthi, Sammanda Ramamoorthy
Behavioural Brain Research, 2021
Glycogen synthase kinase-3ß supports serotonin transporter function and trafficking in a phosphorylation-dependent manner
Durairaj Ragu Varman, Lankupalle D. Jayanthi, Sammanda Ramamoorthy
Journal of Neurochemistry, 2021
Serotonin (5‐HT) transporter (SERT) plays a crucial role in serotonergic transmission in the central nervous system, and any aberration causes serious mental illnesses. Nevertheless, the cellular mechanisms that regulate SERT function and trafficking are not entirely understood. Growing evidence suggests that several protein kinases act as modulators. Here, we delineate the molecular mechanisms by which glycogen synthase kinase‐3ß (GSK3ß) regulates SERT. When mouse striatal synaptosomes were treated with the GSK3α/ß inhibitor CHIR99021, we observed a significant increase in SERT function, Vmax, surface expression with a reduction in 5‐HT Km and SERT phosphorylation. To further study how the SERT molecule is affected by GSK3α/ß, we used HEK‐293 cells as a heterologous expression system. As in striatal synaptosomes, CHIR99021 treatment of cells expressing wild‐type hSERT (hSERT‐WT) resulted in a time and dose‐dependent elevation of hSERT function with a concomitant increase in the Vmax and surface transporters because of reduced internalization and enhanced membrane insertion; silencing GSK3α/ß in these cells with siRNA also similarly affected hSERT. Converting putative GSK3α/ß phosphorylation site serine at position 48 to alanine in hSERT (hSERT‐S48A) completely abrogated the effects of both the inhibitor CHIR99021 and GSK3α/ß siRNA. Substantiating these findings, over‐expression of constitutively active GSK3ß with hSERT‐WT, but not with hSERT‐S48A, reduced SERT function, Vmax, surface density, and enhanced transporter phosphorylation. Both hSERT‐WT and hSERT‐S48A were inhibited similarly by PKC activation or by inhibition of Akt, CaMKII, p38 MAPK, or Src kinase. These findings provide new evidence that GSK3ß supports basal SERT function and trafficking via serine‐48 phosphorylation. image
Inhibition of monoamine oxidase attenuates social defeat-induced memory impairment in goldfish, (Carassius auratus): A possible involvement of synaptic proteins and BDNF
Subramanian Thangaleela, Durairaj Ragu Varman, Karunanithi Sivasangari, Koilmani Emmanuvel Rajan
Comparative Biochemistry and Physiology Part C Toxicology and Pharmacology, 2021
Anorexia induces a microglial associated pro-inflammatory environment and correlates with neurodegeneration in the prefrontal cortex of young female rats
Pamela Reyes-Ortega, Durairaj Ragu Varman, Verónica M. Rodríguez, Daniel Reyes-Haro
Behavioural Brain Research, 2020
Response to Hypoxic Preconditioning of Glial Cells from the Roof of the Fourth Ventricle
Marymar Becerra-González, Ragu Varman Durairaj, Aline Ostos Valverde, Emilio J. Gualda, Pablo Loza-Alvarez, et al.
Neuroscience, 2020
Histamine Receptors Regulate the Activity, Surface Expression, and Phosphorylation of Serotonin Transporters
Balasubramaniam Annamalai, Durairaj Ragu Varman, Rebecca E. Horton, Lynette C. Daws, Lankupalle D. Jayanthi, et al.
ACS Chemical Neuroscience, 2020
A mutation in hnRNPH1 that decreases methamphetamine-induced reinforcement, reward, and dopamine release and increases synaptosomal hnRNP H and mitochondrial proteins
Qiu T. Ruan, Neema Yazdani, Benjamin C. Blum, Jacob A. Beierle, Weiwei Lin, et al.
Journal of Neuroscience, 2020
Anorexia increases microglial density and cytokine expression in the hippocampus of young female rats
Durairaj Ragu-Varman, Mayra Macedo-Mendoza, Francisco Emmanuel Labrada-Moncada, Pamela Reyes-Ortega, Teresa Morales, et al.
Behavioural Brain Research, 2019
GABAρ3 expression in lobule X of the cerebellum is reduced in the valproate model of autism
D.R. Varman, M.B. Soria-Ortíz, A. Martínez-Torres, D. Reyes-Haro
Neuroscience Letters, 2018
Anorexia Reduces GFAP+ Cell Density in the Rat Hippocampus
Daniel Reyes-Haro, Francisco Emmanuel Labrada-Moncada, Durairaj Ragu Varman, Janina Krüger, Teresa Morales, et al.
Neural Plasticity, 2016
Environmental enrichment reduces anxiety by differentially activating serotonergic and neuropeptide y (NPY)-ergic system in Indian field mouse (Mus booduga): An animal model of post-traumatic stress disorder
Durairaj Ragu Varman, Koilmani Emmanuvel Rajan
Plos One, 2015
Activity-dependent expression of miR-132 regulates immediate-early gene induction during olfactory learning in the greater short-nosed fruit bat, Cynopterus sphinx
Murugan Mukilan, Durairaj Ragu Varman, Sivasubramaniam Sudhakar, Koilmani Emmanuvel Rajan
Neurobiology of Learning and Memory, 2015
Environmental enrichment modulates glucocorticoid receptor expression and reduces anxiety in Indian field male mouse Mus booduga through up-regulation of microRNA-124a
Ragu Varman Durairaj, Emmanuvel Rajan Koilmani
General and Comparative Endocrinology, 2014
Environmental enrichment upregulates micro-RNA-183 and alters acetylcholinesterase splice variants to reduce anxiety-like behavior in the little Indian field mouse (Mus booduga)
Durairaj Ragu Varman, Ganapathy Marimuthu, Koilmani Emmanuvel Rajan
Journal of Neuroscience Research, 2013
Egr-1 antisense oligodeoxynucleotide administration into the olfactory bulb impairs olfactory learning in the greater short-nosed fruit bat Cynopterus sphinx
Ambigapathy Ganesh, Wieslaw Bogdanowicz, Krishnaswamy Balamurugan, Durairaj Ragu Varman, Koilmani Emmanuvel Rajan
Brain Research, 2012
Ectoparasite Raymondia lobulata infestation in relation to the reproductive cycle of its host - The greater false vampire bat Megaderma lyra
Arasamuthu Arul Sundari, Wieslaw Bogdanowicz, Durairaj Ragu Varman, Ganapathy Marimuthu, Koilmani Emmanuvel Rajan
Journal of Parasitology, 2012
Environmental enrichment exerts anxiolytic effects in the Indian field mouse (Mus booduga)
Durairaj Ragu Varman, Ganapathy Marimuthu, Koilmani Emmanuvel Rajan
Applied Animal Behaviour Science, 2012
Isolation, Characterization and Identification of a Potential Probiont from South Indian Fermented Foods (Kallappam, Koozh and Mor Kuzhambu) and Its Use as Biopreservative
R. Satish Kumar, D. Ragu Varman, P. Kanmani, N. Yuvaraj, K. A. Paari, et al.
Probiotics and Antimicrobial Proteins, 2010

RECENT SCHOLAR PUBLICATIONS

Antidepressants in intensive care survivors: neuroimmune modulation, clinical outcomes, and translational implications
D Ragu Varman, FA Jayakumar
Journal of Clinical Anesthesia and Intensive care , 2026
2026
Microbiome Driven Modulation of Neurotransmitters: Implications for Neurotransmission and Mood Disorders
BS Sivamaruthi, P Kesika, C Chaiyasut, D Ragu Varman
Frontiers in Microbiology 17, 1750377 , 2026
2026
The Role of Oxytocin-Driven Synaptic Plasticity in Post-Traumatic Stress Disorder: Mechanisms, Therapeutic Potential, and Future Directions
D Ragu Varman, BS Sivamaruthi, FA Jayakumar, N Rehman, R Raju, ...
Current Pharmaceutical Design , 2026
2026
Environmental Contexts and the Neural Basis of Memory and Spatial Navigation.
Subramanian, D., Sri, D. M., Jayakumar, F. A., Ragu Varman, Durairaj.
European Journal of Clinical and Biomedical Sciences 12 (1), 7-16 , 2026
2026
The Dynorphin–Kappa Opioid System as a Salience Gatekeeper in Schizophrenia
D Ragu Varman
Journal of Experimental Neurology 7 (1), 49-54 , 2026
2026
Gut Dysbiosis in Neurodevelopmental Disorders: Linking Microbiota Signatures to Cognitive Rigidity in Autism Spectrum Disorder
BS Sivamaruthi, K Periyanaina, C Chaiyasut, D Ragu Varman
Frontiers in Microbiology 17, 1760635 , 2026
2026
Citations: 2
Causal Mechanisms of Monoamine Transporter Phosphorylation
S Ramamoorthy, D Ragu Varman, LD Jayanthi
Monoamine Transporters, 121-142 , 2025
2025
Citations: 1
Kappa opioid receptor antagonism restores phosphorylation, trafficking and behavior induced by a disease-associated dopamine transporter variant
FP Mayer, A Stewart, D Ragu Varman, AE Moritz, JD Foster, AW Owens, ...
Molecular psychiatry 30 (10), 4651-4664 , 2025
2025
Citations: 8
Discovery of natural orexin 2 receptor antagonists from Valeriana species: A potential approach for insomnia treatment
AG Shenoy, V Ravi, S Subair, D Ragu Varman, R Raju, N Rehman
Chronobiology International 42 (8), 1107-1120 , 2025
2025
Threonine-53 Phosphorylation of Dopamine Transporter Dictates κ-Opioid Receptor-Mediated Locomotor Suppression, Aversion, and Cocaine Reward
D Ragu Varman, S Ramamoorthy, LD Jayanthi
Journal of Neuroscience 45 (25) , 2025
2025
Citations: 3
Spontaneous calcium transients recorded from striatal astrocytes in a preclinical model of autism
H Saavedra-Bonilla, D Ragu Varman, D Reyes-Haro
Neurochemical Research 49 (11), 3069-3077 , 2024
2024
Citations: 5
Dopamine transporter threonine-53 phosphorylation dictates kappa opioid receptor mediated locomotor suppression and conditioned place aversion via transporter upregulation
D Ragu Varman, LD Jayanthi, S Ramamoorthy
bioRxiv, 2024.05. 09.593368 , 2024
2024
Prevalence of cardiovascular diseases in South Asians: scrutinizing traditional risk factors and newly recognized risk factors sarcopenia and osteopenia/osteoporosis
HK Bhotla, A Meyyazhagan, K Pushparaj, M Pappuswamy, A Chaudhary, ...
Current Problems in Cardiology 49 (1), 102071 , 2024
2024
Citations: 10
Striatal synaptic changes and behavior in adult mouse upon prenatal exposure to valproic acid
A Hernandez, E Delgado-Gonzalez, D Ragu Varman, D Reyes-Haro, ...
Brain Research 1815, 148461 , 2023
2023
Citations: 10
Kappa opioid receptor antagonism rescues genetic perturbation of dopamine homeostasis: Molecular, physiological and behavioral consequences
FP Mayer, A Stewart, D Ragu Varman, AE Moritz, JD Foster, AW Owens, ...
BioRxiv , 2023
2023
Citations: 6
Blunted amphetamine-induced reinforcing behaviors and transporter downregulation in Knock-in mice carrying alanine mutations at Threonine-258 and Serine-259 of norepinephrine …
D Ragu Varman, P Mannangatti, MA Subler, JJ Windle, S Ramamoorthy, ...
Journal of Molecular Neuroscience 72 (9), 1965-1976 , 2022
2022
Citations: 3
Neurokinin-1 antagonism distinguishes the role of norepinephrine transporter from dopamine transporter in mediating amphetamine behaviors
P Mannangatti, D Ragu Varman, S Ramamoorthy, LD Jayanthi
Pharmacology 106 (11-12), 597-605 , 2021
2021
Citations: 2
Novelty-induced hyperactivity and suppressed cocaine induced locomotor activation in mice lacking threonine 53 phosphorylation of dopamine transporter
D Ragu Varman, MA Subler, JJ Windle, LD Jayanthi, S Ramamoorthy
Behavioural brain research 408, 113267 , 2021
2021
Citations: 17
Kappa opioid receptor mediated differential regulation of serotonin and dopamine transporters in mood and substance use disorder
D Ragu Varman, LD Jayanthi, S Ramamoorthy
The Kappa Opioid Receptor, 97-112 , 2021
2021
Citations: 9
Inhibition of monoamine oxidase attenuates social defeat-induced memory impairment in goldfish,(Carassius auratus): a possible involvement of synaptic proteins and BDNF
S Thangaleela, D Ragu Varman, K Sivasangari, KE Rajan
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology … , 2021
2021
Citations: 7

MOST CITED SCHOLAR PUBLICATIONS

Environmental enrichment reduces anxiety by differentially activating serotonergic and neuropeptide Y (NPY)-ergic system in Indian field mouse (Mus booduga): an animal model of …
D Ragu Varman, KE Rajan
PLoS One 10 (5), e0127945 , 2015
2015
Citations: 72
A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and …
QT Ruan, N Yazdani, BC Blum, JA Beierle, W Lin, MA Coelho, EK Fultz, ...
The Journal of Neuroscience 40 (1), 107-130 , 2020
2020
Citations: 59
Isolation, Characterization and Identification of a Potential Probiont from South Indian Fermented Foods (Kallappam, Koozh and Mor Kuzhambu) and Its Use as Biopreservative
VA R. Satish Kumar, D. Ragu Varman, P. Kanmani, N. Yuvaraj, K. A. Paari, V ...
Probiotics and Antimicrobial Proteins 2 (3), 143-151 , 2010
2010
Citations: 52
Environmental enrichment modulates glucocorticoid receptor expression and reduces anxiety in Indian field male mouse Mus booduga through up-regulation of microRNA-124a.
D Ragu Varman, KE Rajan
General and Comparitive endocrinology 199, 26-32 , 2014
2014
Citations: 33
Anorexia reduces GFAP+ cell density in the rat hippocampus
D Reyes-Haro, FE Labrada-Moncada, D Ragu Varman, J Krüger, ...
Neural Plasticity 2016 (1), 2426413 , 2016
2016
Citations: 28
Anorexia induces a microglial associated pro-inflammatory environment and correlates with neurodegeneration in the prefrontal cortex of young female rats
P Reyes-Ortega, D Ragu Varman, VM Rodríguez, D Reyes-Haro
Behavioural brain research 392, 112606 , 2020
2020
Citations: 27
Anorexia increases microglial density and cytokine expression in the hippocampus of young female rats
D Ragu-Varman, M Macedo-Mendoza, FE Labrada-Moncada, ...
Behavioural brain research 363, 118-125 , 2019
2019
Citations: 26
Glycogen synthase kinase-3ß supports serotonin transporter function and trafficking in a phosphorylation-dependent manner
Ragu Varman, Durairaj, Lankupalle D. Jayanthi, Sammanda Ramamoorthy
Journal of Neurochemistry , 2020
2020
Citations: 21
GABAρ3 expression in lobule X of the cerebellum is reduced in the valproate model of autism
DR Varman, MB Soria-Ortíz, A Martínez-Torres, D Reyes-Haro
Neuroscience letters 687, 158-163 , 2018
2018
Citations: 20
Environmental enrichment upregulates micro‐RNA‐183 and alters acetylcholinesterase splice variants to reduce anxiety‐like behavior in the little Indian field mouse (Mus booduga)
D Ragu Varman, G Marimuthu, K Emmanuvel Rajan
Journal of Neuroscience Research 91 (3), 426-435 , 2013
2013
Citations: 20
Histamine receptors regulate the activity, surface expression, and phosphorylation of serotonin transporters
B Annamalai, D Ragu Varman, RE Horton, LC Daws, LD Jayanthi, ...
ACS chemical neuroscience 11 (3), 466-476 , 2020
2020
Citations: 18
Novelty-induced hyperactivity and suppressed cocaine induced locomotor activation in mice lacking threonine 53 phosphorylation of dopamine transporter
D Ragu Varman, MA Subler, JJ Windle, LD Jayanthi, S Ramamoorthy
Behavioural brain research 408, 113267 , 2021
2021
Citations: 17
Activity-dependent expression of miR-132 regulates immediate-early gene induction during olfactory learning in the greater short-nosed fruit bat, Cynopterus sphinx
M Mukilan, D Ragu Varman, S Sudhakar, KE Rajan
Neurobiology of learning and memory 120, 41-51 , 2015
2015
Citations: 13
Egr-1 antisense oligodeoxynucleotide administration into the olfactory bulb impairs olfactory learning in the greater short-nosed fruit bat Cynopterus sphinx
A Ganesh, W Bogdanowicz, K Balamurugan, D Ragu Varman, KE Rajan
Brain research 1471, 33-45 , 2012
2012
Citations: 12
Environmental enrichment exerts anxiolytic effects in the Indian field mouse (Mus booduga)
D Ragu Varman, G Marimuthu, KE Rajan
Applied Animal Behaviour Science 136 (2-4), 166-173 , 2012
2012
Citations: 11
Prevalence of cardiovascular diseases in South Asians: scrutinizing traditional risk factors and newly recognized risk factors sarcopenia and osteopenia/osteoporosis
HK Bhotla, A Meyyazhagan, K Pushparaj, M Pappuswamy, A Chaudhary, ...
Current Problems in Cardiology 49 (1), 102071 , 2024
2024
Citations: 10
Striatal synaptic changes and behavior in adult mouse upon prenatal exposure to valproic acid
A Hernandez, E Delgado-Gonzalez, D Ragu Varman, D Reyes-Haro, ...
Brain Research 1815, 148461 , 2023
2023
Citations: 10
Ectoparasite Raymondia lobulata infestation in relation to the reproductive cycle of its host—the greater false vampire bat Megaderma lyra
AA Sundari, W Bogdanowicz, D Ragu Varman, G Marimuthu, KE Rajan
The Journal of parasitology 98 (1), 60-62 , 2012
2012
Citations: 10
Kappa opioid receptor mediated differential regulation of serotonin and dopamine transporters in mood and substance use disorder
D Ragu Varman, LD Jayanthi, S Ramamoorthy
The Kappa Opioid Receptor, 97-112 , 2021
2021
Citations: 9
Kappa opioid receptor antagonism restores phosphorylation, trafficking and behavior induced by a disease-associated dopamine transporter variant
FP Mayer, A Stewart, D Ragu Varman, AE Moritz, JD Foster, AW Owens, ...
Molecular psychiatry 30 (10), 4651-4664 , 2025
2025
Citations: 8

Durairaj Ragu Varman

RESEARCH, TEACHING, or OTHER INTERESTS

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS