Rashmi Boppana

EDUCATION

Ph.D. in Pharmaceutical Sciences
Bachelors in Law
Masters in Management

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmaceutical Science, Business and International Management, Drug Discovery, General Pharmacology, Toxicology and Pharmaceutics

Scopus Publications

Novel pH-sensitive interpenetrated network polyspheres of polyacrylamide-g-locust bean gum and sodium alginate for intestinal targeting of ketoprofen: In vitro and in vivo evaluation
Rashmi Boppana, Sushil Yadaorao Raut, G. Krishna Mohan, Biswanath Sa, Srinivas Mutalik, Kakarla Raghava Reddy, Kusal K. Das, Mallanagouda S. Biradar, and Raghavendra V. Kulkarni
Elsevier BV



In vitro and in vivo assessment of novel pH-sensitive interpenetrating polymer networks of a graft copolymer for gastro-protective delivery of ketoprofen
Rashmi Boppana, Raghavendra V. Kulkarni, G. Krishna Mohan, Srinivas Mutalik, and Tejraj M. Aminabhavi
Royal Society of Chemistry (RSC)
Novel pH-sensitive IPN microbeads exhibited drug release in response to changing pH and reduced side effects of ketoprofenin vivo.


Novel pH-sensitive IPNs of polyacrylamide-g-gum ghatti and sodium alginate for gastro-protective drug delivery
Rashmi Boppana, G. Krishna Mohan, Usha Nayak, Srinivas Mutalik, Biswanath Sa, and Raghavendra V. Kulkarni
Elsevier BV



PH-responsive interpenetrating network hydrogel beads of poly(acrylamide)-g-carrageenan and sodium alginate for intestinal targeted drug delivery: Synthesis, in vitro and in vivo evaluation
Raghavendra V. Kulkarni, Rashmi Boppana, G. Krishna Mohan, Srinivas Mutalik, and Navanath V. Kalyane
Elsevier BV



Interpenetrating network hydrogel beads of carboxymethylcellulose and egg albumin for controlled release of lipid lowering drug
Rashmi Boppana, Raghavendra V. Kulkarni, Srinivas S. Mutalik, C. Mallikarjun Setty, and Biswanath Sa
Informa UK Limited
Novel interpenetrating network hydrogel beads of sodium carboxymethylcellulose and egg albumin loaded with a lipid lowering drug, simvastatin, were prepared by ionotropic gelation and covalent cross-linking method. The IPN beads were characterized by differential scanning colorimetric analysis, X-ray diffractometry to understand the crystalline nature of the drug after entrapment into IPN matrix. Fourier transform infrared spectroscopy was used to find the chemical stability of drug in the polymer matrix and scanning electron microscopy was performed to study the surface morphology. The ionically cross-linked beads were capable of releasing drug up to 7 h, whereas the drug release was extended up to 12 h in case of dual cross-linked beads. The beads which were prepared with higher concentration of glutaraldehyde released the drug more slowly. The release data were fitted to an empirical equation to determine the transport mechanism, which indicated the non-Fickian trend for drug transport.


Carboxymethylcellulose - aluminum hydrogel microbeads for prolonged release of simvastatin

RECENT SCHOLAR PUBLICATIONS

Novel pH-sensitive interpenetrated network polyspheres of polyacrylamide-g-locust bean gum and sodium alginate for intestinal targeting of ketoprofen: In vitro and in vivo
R Boppana, SY Raut, GK Mohan, B Sa, S Mutalik, KR Reddy, KK Das, ...
Colloids and Surfaces B: Biointerfaces 180, 362-370 2019



In vitro and in vivo assessment of novel pH-sensitive interpenetrating polymer networks of a graft copolymer for gastro-protective delivery of ketoprofen
R Boppana, RV Kulkarni, GK Mohan, S Mutalik, TM Aminabhavi
RSC advances 6 (69), 64344-64356 2016



Novel pH-sensitive IPNs of polyacrylamide-g-gum ghatti and sodium alginate for gastro-protective drug delivery
R Boppana, GK Mohan, U Nayak, S Mutalik, B Sa, RV Kulkarni
International journal of biological macromolecules 75, 133-143 2015



Development and Evaluation of Microbeads Using Modified Polysaccharides for Controlled Release of Ketoprofen

64th Indian Pharmaceutical Congress, Chennai, India 2012



pH-responsive interpenetrating network hydrogel beads of poly (acrylamide)-g-carrageenan and sodium alginate for intestinal targeted drug delivery: Synthesis, in vitro and in
RV Kulkarni, R Boppana, GK Mohan, S Mutalik, NV Kalyane
Journal of Colloid and Interface Science 367 (1), 509-517 2012



Interpenetrating network hydrogel beads of carboxymethylcellulose and egg albumin for controlled release of lipid lowering drug
R Boppana, RV Kulkarni, SS Mutalik, CM Setty, B Sa
Journal of microencapsulation 27 (4), 337-344 2010



Carboxymethylcellulose-aluminum hydrogel microbeads for prolonged release of simvastatin
R Boppana, RV Kulkarni, CM Setty, NV Kalyane
Acta pharmaceutica sciencia 52 (2) 2010



Preparation and Evaluation of Hydrogel Beads of Simvastatin

60th Indian Pharmaceutical Congress, Delhi, India 2008



Development and Evaluation of Controlled release Beads of Lipid Lowering Drug using Natural Polymers

National Women's Science Congress organized by Swadeshi Vijnana Andolana 2008



Development and evaluation of xyloglucan matrix tablets containing naproxen
RV Kulkarni, A Shah, R Boppana
Asian Journal of Pharmaceutics (AJP) 2 (2) 2008



Preparation and Evaluation of Controlled Release Multiunit Dosage Forms of Simvastatin

59th Indian Pharmaceutical Congress; Varanasi, India 2007

MOST CITED SCHOLAR PUBLICATIONS

pH-responsive interpenetrating network hydrogel beads of poly (acrylamide)-g-carrageenan and sodium alginate for intestinal targeted drug delivery: Synthesis, in vitro and in
RV Kulkarni, R Boppana, GK Mohan, S Mutalik, NV Kalyane
Journal of Colloid and Interface Science 367 (1), 509-517 2012
Citations: 193



Novel pH-sensitive IPNs of polyacrylamide-g-gum ghatti and sodium alginate for gastro-protective drug delivery
R Boppana, GK Mohan, U Nayak, S Mutalik, B Sa, RV Kulkarni
International journal of biological macromolecules 75, 133-143 2015
Citations: 45



Interpenetrating network hydrogel beads of carboxymethylcellulose and egg albumin for controlled release of lipid lowering drug
R Boppana, RV Kulkarni, SS Mutalik, CM Setty, B Sa
Journal of microencapsulation 27 (4), 337-344 2010
Citations: 42



Carboxymethylcellulose-aluminum hydrogel microbeads for prolonged release of simvastatin
R Boppana, RV Kulkarni, CM Setty, NV Kalyane
Acta pharmaceutica sciencia 52 (2) 2010
Citations: 41



Development and evaluation of xyloglucan matrix tablets containing naproxen
RV Kulkarni, A Shah, R Boppana
Asian Journal of Pharmaceutics (AJP) 2 (2) 2008
Citations: 28



Novel pH-sensitive interpenetrated network polyspheres of polyacrylamide-g-locust bean gum and sodium alginate for intestinal targeting of ketoprofen: In vitro and in vivo
R Boppana, SY Raut, GK Mohan, B Sa, S Mutalik, KR Reddy, KK Das, ...
Colloids and Surfaces B: Biointerfaces 180, 362-370 2019
Citations: 27



In vitro and in vivo assessment of novel pH-sensitive interpenetrating polymer networks of a graft copolymer for gastro-protective delivery of ketoprofen
R Boppana, RV Kulkarni, GK Mohan, S Mutalik, TM Aminabhavi
RSC advances 6 (69), 64344-64356 2016
Citations: 26

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

Patent - IN 282337 (India) : PHARMACEUTICAL COMPOSITION COMPRISING TAMARIND SEED POLYOSE FOR MODIFIED RELEASE OF DRUG