RAVI HARI PHULWARE

Molecular landscape of Hereditary cancer gene panel in urinary bladder cancer in young adults of Sub Himalayan region of Uttarakhand and Western Uttar Pradesh

There is limited information on an exome scale about the germline molecular alteration leading to urinary bladder cancer in young patients in India. Patients from Uttarakhand and Western Uttar Pradesh are usually from low socioeconomic strata and come with advanced stages of tumor. Hence there is a felt need of doing exome profiling study to pick up the gene mutations in this region. This will add to the understanding of the pathogenesis of disease and will help in making a gene panel for early screening and detection.