Renata Calciolari Rossi
@unoeste.br
Departamento de Patologia
Universidade do Oeste Paulista
Graduada em Fisioterapia pela Universidade de Uberaba, Especialista em Saúde Coletiva, Mestre e Doutora em Patologia Geral pela Universidade Federal do Triângulo Mineiro. Possui Pós-doutorado em Anatomia Patológica pela Universidade de São Paulo. Atualmente é Docente do Curso de Graduação em Medicina na disciplina de "Patologia Geral" na Universidade do Oeste Paulista (UNOESTE). Nesta mesma Universidade, atua como Docente no curso de Pós-graduação lato sensu em Geriatria. No curso de Pós-graduação stricto sensu em Meio Ambiente e Desenvolvimento Regional, atua como docente permanente do programa. No curso de Pós-graduação Stricto sensu em Ciências da Saúde também é docente Permanente. Sua linha de pesquisa está relacionada à Patologia Geral e Pulmonar, bem como suas relações com Poluentes Ambientais.
EDUCATION
Graduação em Fisioterapia
Mestrado e doutorado em Ciências da Saúde - Patologia
Pós-doutorado em Anatomia Patológica
RESEARCH, TEACHING, or OTHER INTERESTS
Environmental Science, Pollution, Pathology and Forensic Medicine, Pulmonary and Respiratory Medicine
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Natália de Souza Xavier Costa, Aila Mirtes Teles, Jôse Mára de Brito, Thaís de Barros Mendes Lopes, Renata Calciolari Rossi, Fernanda Magalhães Arantes Costa, Beatriz Mangueira Saraiva-Romanholo, Adenir Perini, Tatiane Katsue Furuya, Alexis Germán Murillo Carrasco,et al.
Ecotoxicology and Environmental Safety Elsevier BV
Claudio Pedrassoli Junior, Gabriela Vidotto Cavallieri, Francisco Assis da Silva, Geovana Letícia Fernandes, Gisele Alborghetti Nai, Ana Karina Marques Salge, Josiano Guilherme Puhle, Debora Tavares de Resende e Silva, Danillo Roberto Pereira, Fabíola de Azevedo Mello,et al.
Environmental Science and Pollution Research Springer Science and Business Media LLC
The herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) is widely used in agriculture to control various weeds. The objective of this study was to use the digital image processing method to identify alveolar lesions in the lungs of rats submitted to chronic 2,4-dichlorophenoxyacetic acid (2,4-D) inhalation exposure. We used forty adult male Wistar rats. The rats were divided into four groups: control group (CG), low concentration group (LCG), medium concentration group (MCG), and high concentration group (HCG). In a 6-month exposure period, we used two boxes connected to ultrasonic nebulizers for herbicide spraying. After this period, the rats were euthanized for the collection and study of lung tissue. For each image, counts of injuries and blisters were performed automatically using a methodology based on digital image processing techniques. For analysis of the results, an electronic database (Excel®) was created. We used the Pearson method for correlation analysis; values of p <0.05 were considered significant. In the evaluation of healthy alveoli, we recorded positive and significant correlations between analysis from a pathologist and computational analysis. In the evaluation of injured alveoli, we recorded a positive but non-significant correlation between analysis from a pathologist and computational analysis. These results show the effectiveness of digital image processing when evaluating alveolar integrity.
Matheus Pelinski da Silveira, Kimberly Kamila da Silva Fagundes, Matheus Ribeiro Bizuti, Édina Starck, Renata Calciolari Rossi, and Débora Tavares de Resende e Silva
Springer Science and Business Media LLC
Tália Cássia Boff, Alexandre Bachietti Scaramussa, Manuela Christianetti, Renata Calciolari Rossi, and Débora Tavares de Resende e Silva
Universidade de Sao Paulo, Agencia USP de Gestao da Informacao Academica (AGUIA)
A tecnologia destaca-se como agente de avanço, principalmente na área da saúde. O estudo da anatomia humana nos cursos de medicina permanece tradicionalista com palestras teóricas e dissecção de cadáveres, por isso, metodologias tecnológicas parecem auxiliar o ensino, tornando-o interativo. Assim, o objetivo do estudo é analisar as perspectivas do uso de tecnologias no ensino da anatomia humana para inseri-las na graduação em medicina. Realizou-se uma revisão sistemática da literatura abrangendo artigos publicados entre janeiro de 2017 a março de 2020 nas bases de dados eletrônicas PubMed e Science Direct. Elencaram-se três critérios de inclusão: estudos com estudantes de medicina ou direcionado aos estudantes de medicina, estudos com residentes de medicina e estudos que avaliam o uso do desenvolvimento tecnológico no ensino da anatomia humana; e três de exclusão: estudos com animais, estudos com estudantes de outros cursos da área da saúde e estudos envolvendo área ou técnica cirúrgica específica. Onze artigos foram lidos na íntegra. Como resultado smartphones, código de resposta rápida (QR), realidade virtual (VR), modalidades impressas tridimensionais (3DP), próteses em 3D e outras tecnologias beneficiaram os alunos no aprendizado anatômico, os quais relataram instrumento atraente, de fácil manejo e acessível mesmo distante do laboratório. Além disso, demonstrou-se maior interesse dos acadêmicos em associar métodos tradicionais com as novas tecnologias. As tecnologias se mostraram eficazes no ensino da anatomia humana, visto que a maior parte dos estudos comprovou seu potencial enriquecedor nas avaliações que atingiram resultados iguais e melhores do que o ensino com as práticas tradicionais.
Fabíola de Azevedo Mello, Beatriz Bertholace Magalhaes Silva, Emmanuela Beatriz Vantini Barreiro, Isabela Benes Franco, Isabela Melo Nogueira, Pedro Henrique Nahas Chagas, José Luiz Santos Parizi, Danillo Roberto Pereira, Renata Calciolari Rossi, and Gisele Alborghetti Nai
Japanese Society of Toxicology
2,4-Dichlorophenoxyacetic acid (2,4-D) is one of the most widely used herbicides in the world, but its mutagenic and carcinogenic potential is still controversial. We simulated environmental exposure to 2,4-D, with the objective of evaluating the genotoxic effect of acute and chronic exposure to 2,4-D in rodents. We also evaluated the performance of machine learning algorithms in detecting differences in exposure groups through recognition performed from genotoxic characteristics. In the acute phase, 88 Swiss mice were used, distributed in five groups and exposed to nebulizations at different time intervals (24, 48, 72 and 192 hr). In the chronic phase, 88 Wistar rats were used, distributed in two groups (inhaled and oral) and exposed for six months. Femoral bone marrow cells were collected for a micronucleus test and comet assay. Data were evaluated by pattern recognition algorithms. In acute exposure, medium and high concentrations induced DNA damage in the comet assay, but these concentrations did not increase micronucleated cells. In the chronic exposure, there was an increase in micronuclei and DNA damage in the comet assay in all exposed groups regardless of the exposure route. The data showed a robust pattern of distinction between exposed and nonexposed groups to 2,4-D. Our data showed that both acute inhalation exposure and chronic oral and inhalation exposure to 2,4-D can cause genotoxic effects regardless of concentration. Machine learning showed a clear distinction between the control groups and those exposed to 2,4-D, and the effects of exposure are not concentration-dependent.
Renata Calciolari Rossi, Raquel Annoni, Diogenes Seraphim Ferreira, Luiz Fernando Ferraz da Silva, and Thais Mauad
Allergy, Asthma and Clinical Immunology Springer Science and Business Media LLC
An amendment to this paper has been published and can be accessed via the original article.
José Luiz Santos Parizi, Amanda Jodas Tolardo, Ana Carolina Gomes Lisboa, Bruna Barravieira, Fabíola de Azevedo Mello, Renata Calciolari Rossi, and Gisele Alborghetti Nai
Springer Science and Business Media LLC
Abstract Background The herbicide dichlorophenoxyacetic acid (2,4-D) is one of the most widely used crop spraying products in the world. Some pesticides induce the degranulation of mast cells and increase allergic responses. This is the first study to evaluate the damage to the oral mucosa after an experimental simulation of environmental inhalation exposure to the 2,4-D herbicide. The aim of this study was evaluate the possible oral damage caused by acute inhalation exposure to the herbicide 2,4-D. Results There was a difference between the exposure concentrations in relation to tissue congestion intensity (p = 0.002) and mast cell counts (p = 0.002), a difference in the evaluation of the interaction between the exposure concentrations and nebulization time in the dorsum epithelium thickness (p = 0.013), and a significant correlation between the epithelial thickness and the number of nucleoli organizing regions on the dorsum of the tongue (p = 0.048). Conclusions Even after acute exposure, the herbicide 2,4-D had the potential to damage the oral epithelium, especially at higher doses.
Renata Calciolari Rossi, Raquel Anonni, Diogenes Seraphim Ferreira, Luiz Fernando Ferraz da Silva, and Thais Mauad
Springer Science and Business Media LLC
Abstract Background There is interest in better understanding vessel pathology in asthma, given the findings of loss of peripheral vasculature associated with disease severity by imaging and altered markers of endothelial activation. To date, vascular changes in asthma have been described mainly at the submucosal capillary level of the bronchial microcirculation, with sparse information available on the pathology of bronchial and pulmonary arteries. The aim of this study was to describe structural and endothelial activation markers in bronchial arteries (BAs) and pulmonary arteries (PAs) of asthma patients who died during a fatal asthma attack. Methods Autopsy lung tissue was obtained from 21 smoking and non-smoking patients who died of an asthma attack and nine non-smoking control patients. Verhoeff–Masson trichrome staining was used to analyse the structure of arteries. Using immuno-histochemistry and image analyses, we quantified extracellular matrix (ECM) components (collagen I, collagen III, versican, tenascin, fibronectin, elastic fibres), adhesion molecules [vascular cell adhesion molecule 1 (VCAM-1) and intercellular adhesion molecule 1 (ICAM-1)] and markers of vascular tone/dysfunction [endothelin-1 (ET-1) and angiotensin II type 2 receptor (AT2)] in PAs and BAs. Results There were no significant differences in ECM components, ICAM-1, ET-1 or AT2 between asthma patients and controls. Smoking asthma patients presented with decreased content of collagen III in both BA (p = 0.046) and PA (p = 0.010) walls compared to non-smoking asthma patients. Asthma patients had increased VCAM-1 content in the BA wall (p = 0.026) but not in the PA wall. Conclusion Our data suggest that the mechanisms linking asthma and arterial functional abnormalities might involve systemic rather than local mediators. Loss of collagen III in the PA was observed in smoking asthma patients, and this was compatible with the degradative environment induced by cigarette smoking. Our data also reinforce the idea that the mechanisms of leukocyte efflux via adhesion molecules differ between bronchial and pulmonary circulation, which might be relevant to understanding and treating the distal lung in asthma.
Marcela Prado Silva Parizi, Arlen Mabel Lastre Acosta, Hamilton Mitsugu Ishiki, Renata Calciolari Rossi, Renata Cristina Mafra, and Antonio Carlos Silva Costa Teixeira
Springer Science and Business Media LLC
Ana Lucia Ribeiro Negrão, Bianca de Oliveira, Mariana de Godoy Gonçalves, Thaoan Bruno Mariano, Tais Fernanda da Silva Oliveira, Ana Karênina Dias Almeida Sabela, Renata Calciolari Rossi e Silva, Raíssa de Oliveira Mantovani, Gisele Alborghetti Nai, and Francis Lopes Pacagnelli
Sociedade Brasileira de Cardiologia
Mailing Address: Francis Lopes Pacagnelli Santo Anastácio, s/n. Postal Code: 19360-000, Jardim América, Santo Anastácio, SP Brazil. E-mail: francispacagnelli@unoeste.br, francispacagnelli@hotmail.com Effect of Short-Term Inhalation of The Herbicide 2,4D on Cardiac Remodeling: Morphological Aspects Ana Lucia Ribeiro Negrão, Bianca de Oliveira, Mariana de Godoy Gonçalves, Thaoan Bruno Mariano, Tais Fernanda da Silva Oliveira, Ana Karênina Dias Almeida Sabela, Renata Calciolari Rossi e Silva, Raíssa de Oliveira Mantovani, Gisele Alborghetti Nai, Francis Lopes Pacagnelli
Fabíola De Azevedo Mello, Giselle Quinallia, Ana Carolina Marion, Fernanda Cardoso Jorge, Laura Monico Marinelli, Ana Karina Marques Salge, Marcela De Andrade Bernal Fagiani, Edson Assunção Mareco, Ana Paula Alves Favareto, and Renata Calciolari Rossi e Silva
Universidade de Sao Paulo, Agencia USP de Gestao da Informacao Academica (AGUIA)
No último ano, o Brasil apresentou um aumento de 190% na utilização de agrotóxicos, o que implica em um grave problema de saúde pública. O ácido 2,4-diclorofenoxiacético possui classificação toxicológica I (extremamente tóxico) e por ser muito volátil, favorece a contaminação de solos, águas, animais e seres humanos. Modelo do estudo: Estudo Experimental. Objetivo: Analisar o infiltrado inflamatório de camundongos submetidos à nebulização aguda ao herbicida ácido 2,4-diclorofenoxiacético, em diferentes intervalos de tempo e concentrações. Métodos: Foram utilizados 80 camundongos Swiss machos divididos em quatro grupos (n=20): salina, baixa (3,71 x 10-3 gramas de ingrediente ativo por hectare), média (6,19 x 10-3 gramas de ingrediente ativo por hectare) e alta concentração (9,28 x10-3 gramas de ingrediente ativo por hectare). Todos os animais foram expostos às nebulizações preconizadas para cada grupo por 15 minutos, em diferentes intervalos de tempo: 24, 48, 72 e 192 horas. O protocolo de exposição contou com duas caixas ligadas a um nebulizador ultrassônico e o vestíbulo nasal de cada animal foi retirado após a eutanásia, para a análise histológica. Resultados: A contagem de mastócitos apresentou valores significativamente aumentados no grupo alta concentração, no intervalo de tempo de 48 horas, quando comparado ao de 24 horas. Conclusão: Os resultados mostraram que a exposição aguda ao herbicida ácido 2,4-diclorofenoxiacético aumenta a produção de mastócitos na cavidade nasal de animais expostos a altas concentrações, e que podem estar relacionados ao surgimento de reações alérgicas.
Monique Buttignol, Ruy Camargo Pires-Neto, Renata Calciolari Rossi e Silva, Marina Ballarin Albino, Marisa Dolhnikoff, and Thais Mauad
Springer Science and Business Media LLC
Kelly Yoshizaki, Jôse Mára Brito, Luiz Fernando Silva, Adriana Lino-dos-Santos-Franco, Daniela Perroni Frias, Renata Calciolari Rossi e Silva, Luís Fernando Amato-Lourenço, Paulo Hilário Nascimento Saldiva, Iolanda de Fátima Lopes Calvo Tibério, Thais Mauad,et al.
Elsevier BV
Cristiane Neves Alessi Pissulin, Ana Angélica Henrique Fernandes, Alejandro Manuel Sanchez Orellana, Renata Calciolari Rossi e Silva, and Selma Maria Michelin Matheus
Elsevier BV
Ana Karina Marques Salge, Renata Calciolari Rossi e Silva, Janaína Valadares Guimarães, Wilzianne Silva Ramalho, Douglas Reis Abdalla, and George Kemil Abdalla
FapUNIFESP (SciELO)
ABSTRACT Objective: to analyze clinical, placental and obstetric aspects of women with and without high-risk pregnancy, and their relationship with intrauterine growth deviations and neonatal aspects. Method: this is a cross-sectional descriptive study. Data collection was based on an analysis of the medical records of women with and without high-risk pregnancy and newborns, and anatomopathological characterization of the placenta. Results: 265 placentas were analyzed, 130 (49.06%) women with high-risk pregnancy and newborns with intrauterine growth deviations. A higher occurrence of placental changes was found in high-risk pregnancy and uterine growth deviations in comparison to cases without high-risk pregnancy (p≤0.001). High-risk pregnancies with intrauterine growth deviations were associated with placental changes (p≤0.001). Intrauterine growth deviations was related to birth weight in cases of high-risk pregnancy compared to normal gestation (p=0.014). Conclusion: a higher occurrence of placental anatomopathological changes was found in maternal and fetal surfaces in cases of high-risk pregnancy and intrauterine growth deviations.
Isabela Malaguti, Paula B. Manfrim, Thamara M. Santos, Daiane C. N. dos Santos, Layane L. Napoleão, Renata C. R. e Silva, and Susimay A. T. Padulla
Universidade de Sao Paulo, Agencia USP de Gestao da Informacao Academica (AGUIA)
Introduction: The hemodialysis is the treatment most used in patients with chronic kidney disease, and the same, limits the activities of patients, favoring sedentary lifestyle, functional disability, depression and anxiety, factors that reflect the quality of their life. Patients who have chronic diseases cling to faith as a way to find support and relief for their pain. Objective: This research has the objective to analyze the relationship between the scores of spirituality to quality of life of these patients. Methods: The study consisted of 100 patients of both sexes undergoing hemodialysis at Kidney Institute, Santa Casa de Misericordia de Presidente Prudente-SP. We used the SF-36 questionnaire to assess quality of life, The Spirituality Rating Scale and The Visual Analogue Scale (VAS) for pain. All statistical procedures were performed in BioEstat (5.0). Results: The score of spirituality was related to the great majority of the SF- 36. The higher scores of spirituality were related to higher scores in vitality, mental health and overall quality of life, even after adjusting for sex, age and VAS. It was possible to identify that the higher the “hope for the future” and “the belief that life has improved” was the best health perception. Conclusions: The Spirituality was shown to be positively related to improvement in quality of life and should be considered by the professionals who attend this kind of patient.
Fernanda Maria Machado Rodrigues, Dionei Ramos, Rafaella Fagundes Xavier, Juliana Tiyaki Ito, Alcirene Policarpo de Souza, Rômulo Araújo Fernandes, Rubens Cecchini, Renata Calciolari Rossi e Silva, Mariangela Macchione, Alessandra Choqueta de Toledo-Arruda,et al.
Elsevier BV
Fabiano F. de Lima, Regina C. V. de Miranda, Renata C. Rossi e Silva, Henrique L. Monteiro, Lin S. Yen, Barbara S. Fahur, and Susimary A. T. Padulla
Universidade de Sao Paulo, Agencia USP de Gestao da Informacao Academica (AGUIA)
Modelo do estudo: Estudo experimental. Introdução: A Doença Renal Crônica (DRC) refere-se a um diagnóstico sindrômico de perda progressiva e irreversível da função renal. O paciente submetido à hemodiálise pode apresentar limitações na capacidade funcional, função pulmonar e força muscular respiratória, com consequentes prejuízos na qualidade de vida. Objetivo: Avaliar os efeitos de um programa de exercício físico sobre a função pulmonar, capacidade funcional, qualidade de vida e dor, em pacientes que realizam hemodiálise. Metodologia: Participaram do estudo 28 pacientes de ambos os sexos, com idade entre 40 e 60 anos, em programa de hemodiálise no Instituto do Rim da Santa Casa de Misericórdia de Presidente Prudente-SP. A força muscular respiratória foi avaliada pela manovacuometria, a capacidade funcional, pelo TC6', a qualidade de vida, pelo questionário KDQOLSF, a função pulmonar, pela espirometria e a dor, pela EVA. Após as avaliações, os pacientes iniciaram o programa de exercícios, que foi desenvolvido três vezes por semana, durante 40 minutos em hemodiálise, por oito semanas. Ao final do programa, os pacientes foram reavaliados. Resultados: Não houve diferença significativa dos valores da CVF e VEF1 pré e pós-programa de exercícios, assim como do Índice de Tiffenau. O valor da PImax pós-programa foi significativamente maior que o obtido na avaliação pré-programa. Para a variável PEmax, não foi encontrada diferença significativa. As avaliações da capacidade funcional inicial e final não apresentaram diferenças significativas (p>0,05). A avaliação da qualidade de vida, quanto aos domínios das áreas específicas da DRC, mostrou que houve significância estatística, ao comparar a lista de sintomas e problemas com a sobrecarga da DRC e papel profissional. Os indicadores relativos à dor foram reduzidos, após o programa (p<0,05). Discussão: O DRC enfrenta situações complexas de dependência física, social e financeira. Apesar de não apresentar resultados estatisticamente significativos em todas as variáveis avaliadas, este estudo, corroborando outros encontrados na literatura, sugere um programa de exercício físico, com aspectos positivos para essa população. Conclusão: Embora a capacidade pulmonar e a capacidade funcional (TC6') não tenham apresentado alterações ao final do experimento, os níveis reduzidos de dor, cansaço e dispneia sugerem melhora do desempenho funcional, após programas de exercício físico para DRC.
Geisielle Pereira Andrade, Mariana Molinar Mauad Cintra, Polyanna Miranda Alves, Octávio Barbosa Neto, Renata Calciolari Rossi E Silva, Valdo José Dias Da Silva, Marlene Antônia Dos Reis, and Débora Tavares De Resende E Silva Abate
SAGE Publications
Hypertension is a major risk factor for cardiovascular diseases, in which the elastic properties of arteries are subjected to high pressure levels, and networks of elastic fibers may develop cleft longitudinal, transverse, breaks and fragmentation, and such structural changes (fibrosis and degradation of elastin) may lead to a decrease in the elasticity of the artery. The descending thoracic aortas of normotensive Wistar Kyoto (WKY) and spontaneously hypertensive rats (SHRs) subjected to physical training through swimming or those of sedentary rats were prepared with hematoxylin-eosin and Verhoff to assess the artery medial. The images were captured with a videocamera coupled to an ordinary light microscope and the images were analyzed with the same program. SHRs showed a larger area of the medial layer of the thoracic aorta (F = 25,764, P, 0.001), and it was observed that rats submitted to physical training through swimming showed a larger area of the thoracic aorta (t = 3.206, P = 0.011). There was a higher percentage of elastic trained (F = 6.536, P = 0.019). To conclude, this study aimed to determine the elastic component of the aortic artery in animals that underwent exercise when compared with those that did not perform the activity, and analyze the relationship between the area of the aortic wall in trained and sedentary animals. The principal conclusion is that the rigidity of the aorta is not increased in SHRs subjected to physical training compared with that of trained WKY animals; however, when sedentary SHRs were analyzed there was a decrease in the elasticcomponent, which can characterize the aortic arterial stiffness in SHRs.
Renata Calciolari Rossi e Silva, Janainna Grazielle Pacheco Olegário, Débora Tavares de Rezende e Silva Abate, Ana Karina Marques Salge, Luiz César Peres, Rosana Rosa Miranda Corrêa, Eumenia Costa da Cunha Castro, and Vicente de Paula Antunes Teixeira
Elsevier BV
Débora Tavares de Resende e Silva Abate, Octavio Barbosa Neto, Renata Calciolari Rossi e Silva, Ana Carolina Guimarães Faleiros, Rosana Rosa Miranda Correa, Valdo José Dias da Silva, Eumênia Costa da Cunha Castro, and Marlene Antônia Reis
Informa UK Limited
Assess the effects of exercise-training on resting arterial pressure and heart rate, placental fetuses morphologic alterations in pregnant spontaneously hypertensive rats (SHRs).Twenty SHRs and their respective control normotensive rats (WKY) were submitted or not to a swimming protocol during 9 weeks, resulting in four pregnant experimental groups: sedentary hypertensive (PSH), trained hypertensive (PTH), sedentary normotensive (PSN), and trained normotensive (PTN). Exercise-training by swimming attenuates arterial pressure in pregnant SHRs, and can contribute to an increase in the length of fetuses and the percentage of the vessels in the placenta.
Ana Karina Marques Salge, Karlla Morgana Nunes Rocha, Raphaela Maioni Xavier, Wilzianne Silva Ramalho, Érika Lopes Rocha, Janaína Valadares Guimarães, Renata Calciolari Rossi e Silva, Karina Machado Siqueira, Douglas Reis Abdalla, Márcia Antoniazzi Michelin,et al.
Elsevier BV
OBJECTIVES: The current study sought to identify macroscopic placental changes associated with clinical conditions in women with or without diabetes and their newborns. METHODS: The study population consisted of 62 pregnant women clinically diagnosed with diabetes and 62 healthy women (control group). RESULTS: Among the subjects with diabetes, 43 women (69.3%) were diagnosed with gestational diabetes mellitus, 15 had diabetes mellitus I (24.2%), and four had diabetes mellitus II (6.5%). The mean age of the women studied was 28.5±5.71 years, and the mean gestational age of the diabetic women was 38.51 weeks. Of the 62 placentas from diabetic pregnancies, 49 (79%) maternal surfaces and 59 (95.2%) fetal surfaces showed abnormalities, including calcium and fibrin deposits, placental infarction, hematoma, and fibrosis. A statistical association was found between newborn gender and fetal and maternal placental changes (p = 0.002). The mean weight of the newborns studied was 3,287±563 g for women with diabetes mellitus, 3,205±544 g for those with gestational diabetes mellitus, 3,563±696 g for those with diabetes mellitus II, and 3,095±451 g for those with diabetes mellitus I. CONCLUSIONS: Infarction, hematoma, calcification, and fibrin were found on the maternal and fetal placental surfaces in women with diabetes. Women with gestational diabetes and post-term infants had more calcium deposits on the maternal placental surface as compared to those with type I and type II diabetes.
Natália Dias B. Guimarães, Ana Paula Espindula, Laura Penna Rocha, Janaínna Grazielle Pacheco Olegário, Débora Tavares Resende Silva Abate, Renata Calciolari Rossi e Silva, Camila Lourencini Cavellani, Marlene Antônia dos Reis, Vicente de Paula Antunes Teixeira, Eumenia Costa da Cunha Castro,et al.
Elsevier BV
Renata Calciolari Rossi-and-Silva, Janainna Grazielle P. Olegário, Rosana Rosa M. Corrêa, Ana Karina M. Salge, Luiz C. Peres, Marlene A. Reis, A. Teixeira Vicente de Paula, and Eumenia Costa C. Castro
Elsevier BV