Renata Carolina Zanetti Lofrano

@ufsj.edu.br

Professora do Departamento de Engenharia Química da UFSJ
UNIVERSIDADE FEDERAL DE SÃO JOÃO DEL REI

Renata Carolina Zanetti Lofrano


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https://researchid.co/renataczlofrano

RESEARCH, TEACHING, or OTHER INTERESTS

Organic Chemistry, Environmental Science, Environmental Chemistry, Chemical Engineering
18

Scopus Publications

Scopus Publications

  • Modeling and Optimization of a Combined Ozonation and Microalgae Cultivation Process using Nutrients from Landfill Leachate
    Nanda Souza Duarte, Vagner Knupp, Gisella Lamas Samanamud, Mateus Souza Amaral, Renata Carolina Zanetti Lofrano, et al.
    Waste and Biomass Valorization, 2026
    To couple an integrated system for the optimized cultivation of Chlorella vulgaris in a photobioreactor, using real-time monitoring through an RGB sensor, together with pretreatment by ozonation in a rotating packed bed (RPB) reactor, this study applied response surface methodology based on a Central Composite Design (CCD) and multiobjective optimization using the Normal Boundary Intersection (NBI) algorithm. Raw landfill leachate presented initial values of COD = 3540 mg L⁻1, BOD = 312 mg L⁻1, NH₃–N = 2965 mg L⁻1 and an initial BOD/COD ratio of 0.08. The ozonation pretreatment was carried out in an RPB reactor operating at 1000 rpm, with ozone concentrations ranging from 2.0 to 10.8 g O₃ m⁻3 and pH values between 4.3 and 9.2. Under optimized conditions (pH ≈ 7.0 and ozone concentration ≈ 2.7 g O₃ m⁻3), the BOD/COD ratio increased from 0.08 to approximately 0.28–0.30, representing an increase of more than 250%, while COD was reduced by up to 70%. Although ammoniacal nitrogen removal during ozonation was limited, NH₃–N concentrations decreased from 2965 mg L⁻1 to approximately 2024 mg L⁻1, enabling its subsequent use as a nutrient source for microalgal cultivation. Batch cultivation assays using treated leachate (80 mL) mixed with microalgal culture (120 mL) demonstrated effective nitrogen assimilation, achieving residual NH₃–N concentrations below 300 mg L⁻1 and biomass concentrations up to 299 mg L⁻1. The integration of automated monitoring based on RGB color stabilization allowed real-time identification of the stationary growth phase and controlled feeding of pretreated leachate. The combined ozonation–microalgae system demonstrated technical feasibility, reduced external nutrient demand by up to 75%, and enhanced biomass production using landfill leachate as a macronutrient source. This integrated and optimized approach represents a sustainable strategy for landfill leachate valorization, combining advanced oxidation, process automation, and microalgal biotechnology. Graphical Abstract
  • Application of sugarcane bagasse and peanut shell in natura as bioadsorbents for vinasse treatment
    Felipe de Aquino Lima, Antônio Carvalho dos Santos Júnior, Boutros Sarrouh, Renata Carolina Zanetti Lofrano
    Clean Technologies and Environmental Policy, 2024
  • Application of sugarcane bagasse and peanut shell in natura as bioadsorbents for vinasse treatment
    Felipe de Aquino Lima, Antônio Carvalho dos Santos Júnior, Boutros Sarrouh, Renata Carolina Zanetti Lofrano
    Clean Technologies and Environmental Policy, 2024
  • POTENCIAL CITRIC ACID PRODUCTION BY FUNGI USING HEMICELLULOSIC HYDROLYSATE OF COFFEE HUSK AS SUBSTRATE
    Boutros Sarrouh, Renata Carolina Zanetti Lofrano
    Revista De Gestao Social E Ambiental, 2024
    Objective: The aim of this experimental assay was to produce citric acid via submerged fermentation, using hemicellulose hydrolysate from coffee husks as main substrate. Theoretical framework: Obtaining citric acid through fermentation processes, especially submerged fermentation, has become viable due to the use of low-cost materials, such as industrial subproducts derived from green biomass. Methodology: The hemicellulose hydrolysate was obtained from the acid hydrolysis process of the coffee husk. The strains of the fungi Aspergillus niger, Aspergillus westerdijkiae and Rhizopus sp. were employed to carry out the fermentation assays. A bioreactor consisting of a 500 ml flat-bottomed flask was used, with an inlet for supplying air and an outlet for removing samples Results and Conclusion: The obtained results showed an increase in number of spores of the studied fungi as well as citric acid accumulation during the first 72 h of fermentation. On the other hand, after 96 h of fermentation citric acid concentration began to decrease indicating its consumption by the studied fungi, probably due to the lack of nitrogen sources and the cellular stress caused by the mixed composition of the hemicellulose hydrolysate. Implications of the research: There is a need to study the interaction between the nitrogenous nutrients to be added to the fermentation medium and the concentration of reducing sugars as the sole carbon source in the lignocellulosic hydrolysate. Originality/value: This work highlights the potential production of citric acid by fungi using a coffee husk as a renewable biomass.
  • Multivariate modeling and optimization of the reverse cationic flotation process of iron ore using depressant-modified starch
    Matheus Furlan Pinheiro, José Izaquiel Santos da Silva, Clarissa Nascimento de Oliveira, Edilailsa Januário de Melo, Alexandre Boscaro França, et al.
    Minerals Engineering, 2024
  • Modeling and optimization of hybrid leachate treatment processes and scale-up of the process
    Fabiano Luiz Naves, Cristiane Medina Finzi Quintão, Mateus de Souza Amaral, Renata Carolina Zanetti Lofrano, Alexandre Boscaro França, et al.
    Landfill Leachate Management, 2023
    Optimized models of landfill leachate processes that could lead to the production of fuel oils from the pyrolysis of plastics and cultivation of microalgae can be highly efficient and have sustainable activities. Studies using advanced oxidation processes in combination with biological processes showed to be efficient in treating leachate. The complexity of this type of waste, as well as the continuous modification of its properties due to local seasonality, prevents kinetic and thermodynamic studies to predict the steady state at the final disposal. Environmental management systems using Lean Six Sigma accompanied by process modeling and optimization tools, whether statistical or computational, generate reliable models. These models can reproduce reductions in contaminants by confirming the initial conditions of each leachate enabling the scale-up of the process. This chapter provides data survey, types of treatment, and models linked to optimization tools in wastewater decontamination processes from municipal solid waste. Also, this chapter includes the synthesis and proposal for treatment and management of the classification of garbage until the generation of leachate, aiming to contribute to future research in the area of leachate treatment.
  • Green chemistry production of biopolymeric film-derived biomaterial prepared using natural alginate and vanillin compounds for application as a biocurative
    Letícia Silveira, Fabiano Luiz Naves, Igor José Boggione Santos, Boutros Sarrouh, Renata Carolina Zanetti Lofrano
    Environmental Science and Pollution Research, 2023
  • Modeling and optimization of the pyrolysis oil production process from polypropylene for the production of aviation kerosene
    Heraclito Alexandre dos Santos, Igor José Boggione Santos, Cristiane Medina Finzi Quintão, Vagner Fernandes Knupp, Renata Carolina Zanetti Lofrano, et al.
    Clean Technologies and Environmental Policy, 2023
  • Extraction and Identification of Biomolecules from Lignin Alkaline Hydrolysate from Coffee Husk
    Boutros Sarrouh, Roberta Oliveira Aguiar de Souza, Raissa Hellen da Silva Florindo, Renata Carolina Zanetti Lofrano, Ana Maria de Oliveira
    Waste and Biomass Valorization, 2021
  • Lipase production by microorganisms isolated from the serra de ouro branco state park
    BÁRBARA D. DA SILVA LUZ, BOUTROS SARROUH, JULIANO L. BICAS, RENATA C.Z. LOFRANO
    Anais Da Academia Brasileira De Ciencias, 2021
    Lipases are hydrolases used in various sectors such as the food, pharmaceutical and chemical synthesis industries. In this study, epiphytic microorganisms were isolated from the Serra of Ouro Branco State Park (Minas Gerais, Brazil) and were subsequently evaluated for their ability to produce extracellular lipases. Among the 46 isolated strains, 25 presented positive results for lipase production in the agar plate screening assay. Two of these strains that expressed the highest diffusion halos, were genetically identified as Serratia marcescens and Pseudomonas fluorescens and catalogued in the Tropical Cultures Collection from the André Tosello Foundation/Brazil as CCT 7796 and CCT 7797, respectively. The fermentation growth kinetics indicated that the maximum extracellular lipase activities were achieved between 96 and 120h of cultivation. The highest lipolytic activity for both strains was observed at an optimum temperature and pH of 37°C and 7.0, respectively. At these conditions, the lipase activity detected in the crude enzymatic extract of both strains was close to 15.0 U/mL. We consider that these species are promising lipase producers for industrial applications.
  • Insights on the preparation and characterization of the poly(glycerol-co-malic acid) from renewable sources
    Thiago Oliveira Cabral, Boutros Sarrouh, Fabiano Luiz Naves, Renata Carolina Zanetti Lofrano
    Clean Technologies and Environmental Policy, 2020
  • Evaluation of the biodegradation of phthalic contaminants originated from polyvinyl chloride commercial films
    Márcia Regina Figueiredo Luzia, Boutros Sarrouh, Renata Carolina Zanetti Lofrano
    Acta Scientiarum Technology, 2020
  • Influence of Obstruction at Gas-Injection Nozzles (Number and Position) in RH Degasser Process
    Luis Carlos Trindade, Johne Jesus M. Peixoto, Carlos Antônio da Silva, Eduardo Prado Baston, Fabiano Luiz Naves, et al.
    Metallurgical and Materials Transactions B Process Metallurgy and Materials Processing Science, 2019
  • Evaluation of the effectiveness of red mud-supported catalysts in combination with ozone and TiO2 in the treatment of solution containing benzene, toluene, and xylene
    Bernardo Alves de Lima, Pedro Paulo Rocha de Castro, Alexandre Boscaro França, Eduardo Prado Baston, Renata Carolina Zanetti Lofrano, et al.
    Environmental Monitoring and Assessment, 2018
  • Extraction and optimization of tannin from the flower of Musa sp. applied to the treatment of iron ore dump
    Washington Luis Moreira Braga, Jaqueline Alves Roberto, Carlos Vaz, Gisella Rossana Lamas Samanamud, Carla Cristina Almeida Loures, et al.
    Journal of Environmental Chemical Engineering, 2018
  • Normal boundary intersection applied as multivariate and multiobjective optimization in the treatment of amoxicillin synthetic solution
    Deberton Moura, Vithor Barcelos, Gisella Rossana Lamas Samanamud, Alexandre Boscaro França, Renata Lofrano, et al.
    Environmental Monitoring and Assessment, 2018
  • Use of the extract of the flower of Musa sp., in the treatment from coagulation – Flocculation, of iron ore fines
    Carlos Vaz, Mariana Almeida, Pamela Gonçalves, Jaqueline Roberto, Alexandre Boscaro França, et al.
    Journal of Environmental Chemical Engineering, 2018
  • Use of tannin from the Musa sp flower in the treatment of effluent from the leather industry
    23rd International Congress of Chemical and Process Engineering Chisa 2018 and 21st Conference on Process Integration Modelling and Optimisation for Energy Saving and Pollution Reduction Pres 2018, 2018