Herb Genomics: Insight into Traditional Medicinal Herbs to Treat Different Human Ailments S Elavarasi, K Saravanan, G Revathi Herbal Wealth of the Asia Pacific Genomics Medicinal Uses and Conservation, 2025 Traditional medicinal herbs have been utilized for centuries as remedies for various human ailments. With the advent of genomic technologies, researchers are now delving into the genetic makeup of these plants, a field known as HerbGenomics. This review provides an overview of HerbGenomics, focusing on its potential to uncover the genetic basis of traditional medicinal herbs and their therapeutic properties. The authors discuss the application of genomic techniques in elucidating the biosynthetic pathways of bioactive compounds, identifying candidate genes for medicinal traits, and exploring the genetic diversity of medicinal plant populations. Furthermore, this chapter highlights the implications of HerbGenomics in drug discovery, sustainable agriculture, and the integration of traditional herbal knowledge with modern scientific approaches. Overall, HerbGenomics holds immense promise for advancing our understanding of traditional herbal medicine and harnessing the therapeutic potential of medicinal plants for human health.
Targeting SARS-CoV2 spike glycoprotein: molecular insights into phytocompounds binding interactions–in-silico molecular docking K. Saravanan, S. Elavarasi, G. Revathi, P. Karuppannan, M. Ashokkumar, C. Muthusamy, A. Ram Kumar Journal of Biomaterials Science Polymer Edition, 2025 This study utilized small molecular characterization and docking study to evaluate the binding affinity of seven antiviral phytocompounds with the SARS CoV-2 variants (SARS-CoV-2 Spike Glycoprotein, SARS-CoV-2 Spike Protein Variant in 1-RBD, Alpha Variant SARS-CoV2- Spike Protein). The results revealed that five of seven compounds, possesses excellent drug lead property reveled through in-silico ADMET analysis. In addition, six of seven except D-Glucosamine, exhibited excellent binding affinity. Six ligands possess significant binding affinity towards SARS-CoV-2 variants 6VXX, 7LWV and 7R13, which is certainly greater than Remdesivir. Fagaronine found to be the best drug candidate against SARS-CoV-2 variants, It was found that -7.4, -5.6 and -6.3 is the docking score respectively. Aranotin, Beta aescin, Gliotoxin, and Fagaronine formed hydrogen bonds with specific amino acids and exhibited significant binding interactions. These findings suggest that these phytocompounds could be promising candidates for developing antiviral therapies against SARS-CoV-2. Moreover, the study underscores the importance of molecular docking in understanding protein-ligand interactions and its role in drug discovery. The documented pharmacological properties of these compounds in the literature further support their potential therapeutic relevance in various diseases.
Traditional use of herbal plants for the treatment of diabetes in India T. Pullaiah, K. V. Krishnamurthy, B. Bahadur Ethnobotany of India Volume 3 North East India and the Andaman and Nicobar Islands, 2017 Ethnobotany of India: Volume 3: North-East India and Andaman and Nicobar Islands is the third of a five-volume set of Ethnobotany of India. Bringing together in one place the important information on the ethnobotany of the North-East India and Andaman and Nicobar Island region of India, this informative volume presents the details of the tribes of the region, their numbers, their habitat, their culture, and particularly their usage of plants for various purposes.
Evaluation of toxic effect of traditionally used antidiabetic polyherbal formulation on albino rats International Journal of Pharma and Bio Sciences, 2015
Antihyperlipidemic activity of Biophytum sensitivum extracts in streptozotocin (STZ) induced diabetic albino rats International Journal of Pharma and Bio Sciences, 2015
