Filipa Raquel Maia Fontes Lebre

@inl.int

Research Fellow - Nanosafety Group
International Iberian Nanotechnology Laboratory



              

https://researchid.co/filebre

RESEARCH INTERESTS

Biomaterials; immunomodulation; tissue engineering

737

Scholar Citations

15

Scholar h-index

16

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Exposure to the phthalate metabolite MEHP impacts survival and growth of human ovarian follicles in vitro
    EM Panagiotou, A Damdimopoulos, T Li, E Moussaud-Lamodire, ...
    Toxicology, 153815 2024

  • Exploring the immunomodulatory properties of glucan particles in human primary cells
    S Jesus, JP Costa, M Colao, F Lebre, D Mateus, AI Sebastio, MT Cruz, ...
    International Journal of Pharmaceutics 655, 123996 2024

  • Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials
    S Costa, V Vilas-Boas, F Lebre, JM Granjeiro, CM Catarino, LM Teixeira, ...
    Trends Biotechnol 2023

  • Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses
    MLE Lundahl, M Mitermite, DG Ryan, S Case, NC Williams, M Yang, ...
    Elife 11, e74690 2022

  • Nanosafety: an evolving concept to bring the safest possible nanomaterials to society and environment
    F Lebre, N Chatterjee, S Costa, E Fernndez-de-Gortari, C Lopes, ...
    Nanomaterials 12 (11), 1810 2022

  • Mycobacterial para-Hydroxybenzoic Acid-Derivatives (pHBADs) and Related Structures Induce Macrophage Innate Memory
    M Lundahl, DM Lynch, D Barnes, L McSweeney, A Gorman, F Lebre, ...
    ACS Chemical Biology 15 (9), 2415-2421 2020

  • Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease
    RK Shears, LC Jacques, G Naylor, L Miyashita, S Khandaker, F Lebre, ...
    Journal of allergy and clinical immunology 145 (4), 1272-1284. e6 2020

  • Pristine graphene induces innate immune training
    F Lebre, JB Boland, P Gouveia, AL Gorman, MLE Lundahl, RI Lynch, ...
    Nanoscale 12 (20), 11192-11200 2020

  • Easy and effective method to generate endotoxin-free chitosan particles for immunotoxicology and immunopharmacology studies
    F Lebre, EC Lavelle, O Borges
    Journal of Pharmacy and Pharmacology 71 (6), 920-928 2019

  • Chitosan plus compound 48/80: formulation and preliminary evaluation as a hepatitis B vaccine adjuvant
    D Bento, S Jesus, F Lebre, T Gonalves, O Borges
    Pharmaceutics 11 (2), 72 2019

  • Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles
    F Lebre, MCP de Lima, EC Lavelle, O Borges
    International journal of pharmaceutics 552 (1-2), 7-15 2018

  • Exfoliation in endotoxin‐free albumin generates pristine graphene with reduced inflammatory properties
    F Lebre, D Hanlon, JB Boland, J Coleman, EC Lavelle
    Advanced Biosystems 2 (12), 1800102 2018

  • Association of chitosan and aluminium as a new adjuvant strategy for improved vaccination
    F Lebre, D Bento, J Ribeiro, M Colaco, G Borchard, MCP de Lima, ...
    International journal of pharmaceutics 527 (1-2), 103-114 2017

  • The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation
    F Lebre, R Sridharan, MJ Sawkins, DJ Kelly, FJ O’Brien, EC Lavelle
    Scientific reports 7 (1), 2922 2017

  • Industrial grade 2D molybdenum disulphide (MoS2): an in vitro exploration of the impact on cellular uptake, cytotoxicity, and inflammation
    C Moore, D Movia, RJ Smith, D Hanlon, F Lebre, EC Lavelle, HJ Byrne, ...
    2D Materials 4 (2), 025065 2017

  • Modulation of immune responses by particulate materials
    F Lebre, CH Hearnden, EC Lavelle
    Advanced Materials 28 (27), 5525-5541 2016

  • Intranasal administration of novel chitosan nanoparticle/DNA complexes induces antibody response to hepatitis B surface antigen in mice
    F Lebre, G Borchard, H Faneca, MC Pedroso de Lima, O Borges
    Molecular pharmaceutics 13 (2), 472-482 2016

  • Chitosan-based nanoparticles as a hepatitis B antigen delivery system
    F Lebre, D Bento, S Jesus, O Borges
    Methods in Enzymology 509, 127-142 2012

  • DEVELOPMENT OF CHITOSAN NANOPARTICLE-DNA COMPLEXES FOR NASAL IMMUNIZATION AGAINST HEPATITIS B
    F Lebre, G Borchard, H Faneca, MC Pedroso de Lima, O Borges
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 44, 139-140 2011

  • Progress towards a needle-free hepatitis B vaccine
    F Lebre, G Borchard, MCP de Lima, O Borges
    Pharmaceutical research 28, 986-1012 2011

MOST CITED SCHOLAR PUBLICATIONS

  • The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation
    F Lebre, R Sridharan, MJ Sawkins, DJ Kelly, FJ O’Brien, EC Lavelle
    Scientific reports 7 (1), 2922 2017
    Citations: 163

  • Mucosal vaccines: recent progress in understanding the natural barriers
    O Borges, F Lebre, D Bento, G Borchard, HE Junginger
    Pharmaceutical research 27, 211-223 2010
    Citations: 93

  • Modulation of immune responses by particulate materials
    F Lebre, CH Hearnden, EC Lavelle
    Advanced Materials 28 (27), 5525-5541 2016
    Citations: 80

  • Intranasal administration of novel chitosan nanoparticle/DNA complexes induces antibody response to hepatitis B surface antigen in mice
    F Lebre, G Borchard, H Faneca, MC Pedroso de Lima, O Borges
    Molecular pharmaceutics 13 (2), 472-482 2016
    Citations: 74

  • Industrial grade 2D molybdenum disulphide (MoS2): an in vitro exploration of the impact on cellular uptake, cytotoxicity, and inflammation
    C Moore, D Movia, RJ Smith, D Hanlon, F Lebre, EC Lavelle, HJ Byrne, ...
    2D Materials 4 (2), 025065 2017
    Citations: 63

  • Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease
    RK Shears, LC Jacques, G Naylor, L Miyashita, S Khandaker, F Lebre, ...
    Journal of allergy and clinical immunology 145 (4), 1272-1284. e6 2020
    Citations: 36

  • Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles
    F Lebre, MCP de Lima, EC Lavelle, O Borges
    International journal of pharmaceutics 552 (1-2), 7-15 2018
    Citations: 35

  • Chitosan plus compound 48/80: formulation and preliminary evaluation as a hepatitis B vaccine adjuvant
    D Bento, S Jesus, F Lebre, T Gonalves, O Borges
    Pharmaceutics 11 (2), 72 2019
    Citations: 31

  • Pristine graphene induces innate immune training
    F Lebre, JB Boland, P Gouveia, AL Gorman, MLE Lundahl, RI Lynch, ...
    Nanoscale 12 (20), 11192-11200 2020
    Citations: 30

  • Progress towards a needle-free hepatitis B vaccine
    F Lebre, G Borchard, MCP de Lima, O Borges
    Pharmaceutical research 28, 986-1012 2011
    Citations: 27

  • Association of chitosan and aluminium as a new adjuvant strategy for improved vaccination
    F Lebre, D Bento, J Ribeiro, M Colaco, G Borchard, MCP de Lima, ...
    International journal of pharmaceutics 527 (1-2), 103-114 2017
    Citations: 21

  • Easy and effective method to generate endotoxin-free chitosan particles for immunotoxicology and immunopharmacology studies
    F Lebre, EC Lavelle, O Borges
    Journal of Pharmacy and Pharmacology 71 (6), 920-928 2019
    Citations: 18

  • Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses
    MLE Lundahl, M Mitermite, DG Ryan, S Case, NC Williams, M Yang, ...
    Elife 11, e74690 2022
    Citations: 17

  • Nanosafety: an evolving concept to bring the safest possible nanomaterials to society and environment
    F Lebre, N Chatterjee, S Costa, E Fernndez-de-Gortari, C Lopes, ...
    Nanomaterials 12 (11), 1810 2022
    Citations: 17

  • Chitosan-based nanoparticles as a hepatitis B antigen delivery system
    F Lebre, D Bento, S Jesus, O Borges
    Methods in Enzymology 509, 127-142 2012
    Citations: 16

  • Exfoliation in endotoxin‐free albumin generates pristine graphene with reduced inflammatory properties
    F Lebre, D Hanlon, JB Boland, J Coleman, EC Lavelle
    Advanced Biosystems 2 (12), 1800102 2018
    Citations: 10

  • Mycobacterial para-Hydroxybenzoic Acid-Derivatives (pHBADs) and Related Structures Induce Macrophage Innate Memory
    M Lundahl, DM Lynch, D Barnes, L McSweeney, A Gorman, F Lebre, ...
    ACS Chemical Biology 15 (9), 2415-2421 2020
    Citations: 4

  • Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials
    S Costa, V Vilas-Boas, F Lebre, JM Granjeiro, CM Catarino, LM Teixeira, ...
    Trends Biotechnol 2023
    Citations: 2