Azmir Ahmad
@iium.edu.my
Assistant Professor, Department of Basic Medical Science for Nursing, Faculty of Nursing
International Islamic University Malaysia
EDUCATION
1. Bachelor Degree in Biomedical Science.
2. Master of Medical Science in Physiology
3. Doctor of Philosophy in Health Science
RESEARCH INTERESTS
My research interests are molecular diagnostic and cancer
Scopus Publications
Scopus Publications
Azmir Ahmad, Syarah Syamimi Mohamed, Afidalina Tumian, Siti Marponga Tolos, Vijaya Mohan Sivanesan, Wan Ishlah Leman, Kahairi Abdullah, Irfan Mohamad, Wan Mohd. Nazri Wan Zainon, Luqman Rosla,et al.
Bogor Agricultural University
In searching for new biomarkers, high throughput technique has been widely used by researchers, including for gene expression study. However, the reliability and accuracy of results from high throughput study critically depends on appropriate data management, including normalization methods. Data driven normalization has been introduced as a normalization method for high throughput gene expression study. Thus, this study was conducted to evaluate the performance of various data driven and reference genes normalization methods using a high throughput circulating microRNA expression dataset. A quantification cycle (Cq) dataset generated from a high throughput circulating microRNA study was used to test the normalization methods using HTqPCR package in R software. The normalized Cq generated from different methods were compared descriptively using box plot analysis and coefficient of variance. The box plot analysis showed that quantile normalization produced more homogenous Cq distribution, lesser outliers and reduced coefficient of variance as compared to other normalization methods in screening and validation phases. The overview on quantile normalized Cq showed consistency in its level of expression before and after 2-∆∆Cq calculation indicating the reliability of quantile normalized Cq. Quantile normalization is suggested to be used in high throughput miRNA expression study due to its performance in homogenizing the data, reduce outliers and coefficient of variance.
Che Muhammad Khairul Hisyam Ismail, Nicholas M.H. Khong, Azmir Ahmad, Khairani Idah Mokhtar, Widya Lestari, Basma Ezzat Mustafa Alahmad, Azzmer Azzar Abdul Hamid, Mohd Ridzuan Mohd Abd Razak, and Azlini Ismail
Elsevier BV
Ruzmayuddin Mamat, Rusdi Abd Rashid, Sim Maw Shin, Baharudin Ibrahim, Suzaily Wahab, and Azmir Ahmad
Informa UK Limited
BACKGROUND
The emergence of New Psychoactive Substances (NPS), including synthetic psilocybin, has raised concern among health experts due to the numerous health and socioeconomic consequences. The current trend is shifting to the hazardous use of synthetic psilocybin in vaping, and little is known about the prevalence of use, specifically among amphetamine-type stimulants (ATS) users.
METHODS
Interviewer-administered questionnaires were conducted in drug detention centers between March and October 2022. The study was conducted using ASSIST 3.0 and obtained information on the respondents' socio-demographic characteristics and clinical profiles. N = 355 ATS users were enrolled in this study.
RESULTS
The results show a high prevalence of psilocybin vaping among ATS users (182/355, 53.1%). Most of the respondents were males (85.1%) and unmarried (69.3%), with a mean age of 29.2 (SD = 7.3). Across all respondents, five factors were associated with psilocybin vaping: tobacco smoking, aOR =5.790 (95% CI: 1.723, 8.183); cannabis uses, aOR= 9.152 (95% CI: 2.693, 10.396); and alcohol use, aOR= 3.137 (95% CI: 1.461, 5.817). Respondents of the Malay race had higher odds of being involved in psilocybin vaping compared to other races, with aOR= 1.638 (0.043, 2.459). Meanwhile, a reduction in age by 1.9 will increase the likelihood of involvement in psilocybin vaping with aOR = 1.897 (95% CI: 0.857, 1.938).
CONCLUSION
Psilocybin in vaping is growing among ATS users and across all populations. Unfortunately, knowledge regarding the long-term effects on health is limited. Further studies should highlight the harmful effects of psilocybin and the potential risk of psilocybin vaping among the younger population.
Ruzmayuddin Mamat, Rusdi Abd Rashid, Maw Shin Sim, Baharuddin Ibrahim, Suzaily Wahab, and Azmir Ahmad
Informa UK Limited
ATS dependence in Malaysia is growing tremendously across multiracial Malaysian groups, increasing concerns among public health experts and the community. This study highlighted the chronicity of ATS dependence and factors associated with ATS use. Interviewer-administered questionnaires were administered using ASSIST 3.0. A total of N = 327 multiracial people who use ATS were enrolled in this study. The study findings show that 190/327 (58.1%) respondents were ATS dependent. Malays reported the highest number of ATS-dependent (55.8%), followed by Bajau (21.6%) and Kadazan-Dusun (16.8%) ethnic. Across all races, three factors were significantly associated with the ATS dependence: respondents who had a lifetime history of needle sharing aOR = 0.023 (95% CI: 0.003, 0.183) and a lifetime history of heroin use aOR = 0.192 (95% CI: 0.093, 0.396) were at a reduced odd of ATS dependent. Meanwhile, being married reduced the likelihood of becoming dependent on ATS with aOR = 0.378 (95% CI: 0.206, 0.693) compared to being single or divorced. This study revealed that the use of ATS among multiracial Malaysians is alarmingly high, including those in detention centers. Comprehensive harm reduction strategies are urgently needed to prevent the spreading of infectious diseases and other negative health consequences associated with ATS use.
Mohd Azri Abd Jalil, Aifa Syazwani Ag Damit, Farahiya Zalikha Zakaria, Muhammad Kamil Che Hasan, Muhammad Lokman Md Isa, and Azmir Ahmad
IOP Publishing
Abstract Meliponiculture or keeping stingless bee in Malaysia is expanding and has the potential to generate money for the the bottom 40% of income earners (B40). The increased production of stingless bee honey as a complementary medicine as a therapeutic medium for health for a variety of reasons. Thus, this study aimed to explore the experiences and perceptions on the therapeutic effects of stingless bee honey and its potential value in generating economy among the B40 community. Semi-structured interviews were carried out among the B40 community who participated in the Desa Kelulut project of Kampung Bukit Kuin, Kuantan. The data were analysed using thematic analysis. A total of six respondents interviewed in the study out of 20 participants. Four themes emerged, namely, benefit of stingless bee honey; market supply and economy; sustaining the farm; and facilitate income. The participants valued the beneficial properties of the honey toward health and acknowledged the potential of the stingless bee honey to be marketed in Malaysia as well as generating income for the B40 community of Kampung Bukit Kuin, Kuantan.
Azmir Ahmad, Wardah Mohd Yassin, Nor Azlina A Rahman, Wan Ishlah Leman, Luqman Rosla, Mark Paul, Sharifah Nor Ezura Syed Yussof, Kamariah Mohamed@Awang, Kahairi Abdullah, and Mohd Arifin Kader
Penerbit Universiti Sains Malaysia
Background: Nasopharyngeal carcinoma (NPC) is the fifth most common cancer among Malaysians. While several studies have reported the trend of NPC in other states in Malaysia, no studies have reported the trend of NPC in Pahang state. This study was designed to report the number and distribution of newly diagnosed NPC cases in Pahang. Methods: NPC cases that were diagnosed between 2012 and 2017 in two referral hospitals in Pahang were traced. The crude incidence rate (CR) and age-standardised rate (ASR) were calculated to investigate the NPC incidence. Results: There were 143 new cases of NPC reported from the two hospitals. The mean age at diagnosis was 52.0 ± 13.7 years old. The majority of cases involved males (74.1%) with a male to female ratio of 2.9:1. Chinese males were found to have the highest incidence with a mean ASR of 4.7 per 100,000 population. Overall, the mean ASR for Pahang was 2.4 per 100,000 population for males and 0.9 per 100,000 population for females. Conclusion: The total number of NPC cases reveals an increasing trend from 2012 to 2014 and then a slightly decreasing trend from 2015 to 2017. The incidence of NPC in Pahang was intermediate in males and low in females.