Kassim Abdulla Hamza Al-Morshidy
@University of Babylon, Faculty of Science
Prof. Dr. in University of Babylon, Faculty of Science, Department of Biology
Prof. Kassim Abdulla Hamza Al-Morshidy, Ph.D. in parasitology and Immunology and M.Sc. in Parasitology. He is assistant professor at the University of Babylon, College of Science, Iraq. He has a number of works in parasitology and immunology and he have planned to future works in these areas.
EDUCATION
Ph. D.: Biology / Parasites Immunology (2012) - University of Babylon, Iraq.
MSc: Biology / Parasitology (2001) - University of Babylon, Iraq.
BSc: Biology / Microbiology (1993) - University of Babylon, Iraq.
RESEARCH INTERESTS
(1) Parasitology
(2) Protozoology
(3) Parasites Immunology
(4) Parasite Physiology
(5) Animal Physiology
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Aseel Kariem Al-Sultany and Kassim Abdulla Hamza Al-Morshidy
Medknow
Abstract Background: Human amebiasis is caused by Entamoeba histolytica, which is found in many tropical countries. E. histolytica infections are known to have a wide range of clinical consequences. Most infections are asymptomatic; some cause diarrhea and dysentery, and only a few cause extraintestinal consequences, including liver abscess. Single nucleotide polymorphisms (SNPs) are the most prevalent kind of sequence variation in genomes and are regarded as useful genetic markers for exposing the evolutionary history and common genetic variants that explain the heritable risk for common illnesses and effected in the progression of some infections. Objective: Investigation of gene polymorphism of the parameters (interleukin 18 [IL-18], resistin) most susceptible to parasitic infection. Materials and Methods: Stool samples were collected from patients who were attending the (Kerbala Teaching Hospital for children in the holy city of Kerbala), between February 2021 and January 2022. In total, 3748 samples of feces from children between the ages of 1 and 15 years from both gender were tested using both direct smear and acid-fast stain tests in addition to rapid test techniques. Five milliliters of blood were obtained from 25 patients infected with E. histolytica, as well as 5 mL of blood from 25 healthy youngsters (sample control). Results: The result showed the distribution of genotype of IL-18 SNPs in intestinal parasites patient in contrast to the control group; there is an increase in the level of IL-18 in some SNPs, resistin concentration was statistically significantly different between resistin gene polymorphisms. Conclusion: The IL-18 and resistin polymorphism can be considered one of the genetic factors responsible for the progression of E. histolytica infection.
A. Al-sultany and K. Al-Morshidy
Background: Intestinal parasitosis remains an important public health concern worldwide because of its high incidence reached in several countries as well as its nutritional consequences. The role of intestinal parasites in causing morbidity and mortality, as well as the pathogenesis of other infectious diseases, is determined. Intestinal parasitic infection is most common among school-age children and tends to cause high-intensity infection in this age group. Intestinal parasites are divided into two major types: helminths and protozoa. Protozoa are unicellular organisms and belong to the Protista kingdom and can reproduce in the human body which can allow the formation of serious infections. Objectives: The objective of this study was to detect the incidence of intestinal parasites in children attending and hospitalized at Karbala Teaching Hospital in the holy city of Karbala, Iraq. Materials and Methods: Between February 2021 and January 2022, 3748 feces samples from children between the age of 1 and 15 years were tested using both direct smear and acid fast stain test in addition to rapid test techniques. Results: The result showed that the total percentage of infection with intestinal parasites was 13% and recorded five types of intestinal parasites: Entamoeba histolytica (10.54%), Giardia lamblia (2.46%), Cryptosporidium parvum 0.4%, Hymenolepis nana (0.24%), Enterobius vermicularis (0.13%), and Trichomonas hominis (0.03%). Males were more likely to get infected than females, and the incidence of intestinal parasite infection (IPI) changed over the month of the study. Also, the infection with one species has more incidence than two and three species. The age groups of the infected children were likewise impacted by the infection rate. The statistical analysis revealed differences in the percentage of IPI by age and gender of children (P ≤ 0.05). Conclusion: We conclude from the result of the present study that the incidence of infection with E. histolytica is more than that of other intestinal parasites, and intestinal parasites were affected by most epidemiological criteria such as gender, the duration of the study, and age of infected patients.
A. Al-hassnawi, K. A. Al-Morshidy and Nuha Yaarub Al-Harbi
College of Science for Women
تلعب السيتوكينات المحفزة للالتهاب دورا مهما في التواصل بين الخلايا. ففي العقدين الأخيرين ، تم تحديد العديد من السيتوكينات في حليب الإنسان حيث تم العثور على السيتوكينات المثيرة للالتهابات في حليب الإنسان. تتنوع السيتوكينات تبعا لظروف مختلفة مثل الالتهابات المسببة للأمراض التي تحفز بشدة الاستجابة المناعية. تهدف الدراسة الحالية إلى تحديد تراكيز IL1β و TNF-α في النساء المصابات وغير المصابات بالمقوسات الجوندية في محاولة لتوضيح آثار العدوى على السيتوكينات وخاصة في حليب الأم. تم في الدراسة الحالية جمع عينات من مصل اللبن والحليب من 96 عينة (48 مصل موجب و 48 مصل سالب). لتأكيد الاصابة بطفيلي التوكسوبلازما تم استخدام تقنية الفلورة المناعية لهذا الغرض . تم قياس تركيز TNF-α و IL1β بواسطة تقنية ELISA. فيما يتعلق بالحليب TNF-alpha ، اظهرت نتائج الدراسة الحاليةهناك فروق ذات دلالة إحصائية في النساء المصابات بالتوكسوبلازما وغير المصابات بها ، في حين لم يتم العثور على اختلافات إحصائية في TNF-α بين مجموعات الدراسة. أظهر نتائج IL1β اختلافا معنويا فقط بين الحليب والمصل في الأشخاص المصابين وغير المصابين ، بينما لم يتم تسجيل أي اختلافات معنوية في مجموعات أخرى. الخلاصة وبناء على التحليل الإحصائي ، أظهرت الدراسة الحالية دليلا جيدا على أن داء المقوسات هو أحد عوامل الخطر لزيادة السيتوكينات في الحليب. اضافة لذلك قد تشير الزيادة الكبيرة في TNF-α و IL1β في حليب الأم إلى دور رئيسي في إحداث أو تطور الالتهابات في الرضاعة. وبالتالي ، هناك حاجة إلى مزيد من الدراسات لهذا الغرض.
Israa Husam Mohammed Al-Hasheme, Thikra Abed-Aoun Hassan Al-Tammime, and Kassim Abdulla Hamza Al-Morshidy
Africa Health Research Organization
The current study aimed at finding the relationship between infection of intestinal parasites and some hematological (complete blood count) and immunological parameters (histamine, interleukin-5, and IgE) in children visiting and infertile at Karbala Children's Hospital in Kerbala, Iraq. Two thousand and five hundred and forty-one fecessamples examined using both direct smear and flotation methods using a saturated salt solution for children aged 1 to 15 for the period from December 2017 to November 2018. The results showed that the total infection percentage of intestinal parasites was 18.93%. Five species of intestinal parasites recorder: Entamoebahistolytica (14.60%), Giardia lamblia (3.90%), Trichomonas hominis (0.16%), Hymenolepis nana (0.59%) and Enterobius vermicularis (0.08%). The percentage of infection inmale was higher than that of females and the percentage of intestinal parasitic infection fluctuated during the study period. The incidence of infection in the age groups of infected children also affected. The statistical analysis showed significant differences (P< 0.05) between the percentage of intestinal parasitic infection with sex and age of children as well as study months and species of parasites recorded. To conduct the hematological and immunological study, 59 infected children selected (30 males, 29 females) and 31 non-infected children (20 males and 11 females). The blood and serumsof these children obtained and examined by a blood analyzer for the hematological parameters and ELIZA method for immunological parameters. The hematological parameters included RBCs, Hb, PCV, WBCS, Neu., Ba., Es., Ly., Mo., Plt., MCV, MHC, and MCHC. The results of the current study showed the effect of the infection of intestinal parasites on some of the hematological parameters, whether increase or decrease (P < 0.05). The results also showed that other hematological parameters did not affect that infection. The results showed a significant increase (P < 0.05) in IgE, IL-5 and histamineconcentrations in children infected with intestinal parasites compared to non-infected children We conclude from the results of the present study that the infection of intestinal parasites plays an important role in stimulating the immune mechanisms of the body and thus the production of immune materials can harm the body's various tissues.
RECENT SCHOLAR PUBLICATIONS
MOST CITED SCHOLAR PUBLICATIONS
Publications
1- Al-Morshidy, K.A.; Mhaisen, K.T & Al-Zubaidy, A.B. (2004). Parasitic protozoans in the alimentary canal and blood of black rat, Rattus rattus and house mouse, Mus musculus in Hilla city. J. Babylon Univ., Pure Appl. Sci., 9(3): 444-457. (In Arabic with English summary).
2- Al-Morshidy, K.A.; Mhaisen, K.T & Al-Zubaidy, A.B. (2005). Helminths parasitized in the alimentary canal and livers of the black rat Rattus rattus and the house mouse Mus musculus in Hilla city. J. Babylon Univ., Pure Appl. Sci., 10(3): 866-877. (In Arabic with English summary).
3- Al-Morshidy, K.A. (2007). Prevalence of intestinal pathogenic parasites infections in Hilla city, Babylon province, Iraq (in Arabic with English summary). J. Babylon Univ. Pur. Appl. Sci., 14, (1): 179-185.
4- Al-Morshidy, K.A. (2007). Investigation of Hydatidosis among slaughtered animals in Hilla abattoir, Iraq. (In Arabic with English summary). J. Babylon Univ. Pur. Appl. Sci., 14, (2): 145-149.
5- Al-Morshidy, K.A. & Ruth, D.M. (2013). Detection of parasitic phases on some vegetables leaves in Hilla city markets/ Iraq (in Arabic with English summary). Proceeding of 5th international conference of environmental science/ University of Babylon/ Environmental research center/ 3-5 December 2013.
6- Al-Morshidy, K.A. & Al-Amari, M.J.Y. (2015). Detection of parasitic contamination in Hilla city drinking water / Babylon province/ Iraq. Advances in Natural and Applied Sciences 9(3):80-84.
7- Al-Morshidy, K.A.; AlMamoori A.M.J.; B
SOCIAL, ECONOMIC, or ACADEMIC BENEFITS
1- The Biological Society of Iraq.
2- Iraqi Academics Syndicate.
3- The International Society for Development and Sustainability (ISDS).