Ragunathan Muthusamy
@svcop.ac.in
Professor ,Head, Department of Pharmacognosy
Swamy Vivekananda college of Pharmacy, Thiruchengodu, Tamilnadu, India
RESEARCH, TEACHING, or OTHER INTERESTS
Health, Toxicology and Mutagenesis, Pharmacology (medical), Pharmacy, Pharmacy
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Ragunathan Muthuswamy, Ranil Ramana Ragunathan, Senthil Rajan Dharmalingam, Kumarappan Chidambaram, Manimekalai Pichaivel, and Sanghavi
Informatics Publishing Limited
This review explores the potential of Caesalpinia bonducella Linn., particularly its seeds, known as ‘bounducella’ or ‘little ball’, and its impact on diverse pharmacological activities. Its use in treating various illnesses, including male and female reproductive health, has been investigated. The data, gathered from reliable sources worldwide, transcend language barriers and align with Indian Ayurvedic and Siddha Pharmacopoeias. This article has compiled the pharmacognostic and phytochemical profiles of the seeds, emphasizing their influence on reproductive health, potentially aiding in PCOS management and addressing hyperandrogenism. Additionally, the seed extract of this plant has abortifacient and anti-fertility effects, suggesting that it is a potential alternative to Mifepristone. Nevertheless, further in vivo and in vitro research on seed constituents is essential for developing lead molecules for use in allopathic treatment.
Ragunathan Muthuswamy and Senthamarai R
EManuscript Technologies
Elaeocarpus tectorius (Lour.) Poir, Synonym: Elaeocarpus oblongus auct. non Gaertn. Elaeocarpaceae, is a tree, found throughout Western Ghats, South India. The present study indented to establish the pharmacognostical and physicochemical quality control parameters of E.oblongus fruits to avoid confusion in taxonomic identification. Physicochemical evaluation of fruit was carried out according to the guidelines of WHO/QCMMP and Indian Ayurvedic Pharmacopoeia. The elemental analysis was done by using Perkin Elmer 5000 an atomic absorption spectrophotometer. Non glandular unicellular trichomes found to be distinguished character of powder analysis. It was quantified to be 700 µm long and 400 µm thick at the base. Lerachysclereids were found plenty in powder. The rosettes type of calcium oxalate crystals were 15 µm in diameter. Cells of the endosperm showing darkly stained globular bodies and the cotyledon is 170 µm thick. Physio-chemical parameters such as total ash and acid-insoluble ash (2.66% w/w, 0.66% w/w, respectively), extractive values (aqueous 31.068% w/w and alcoholic 30.94% w/w), foreign organic matter (0.5% w/w) and loss on drying (12% w/w) were estimated. Qualitative analysis showed the presence of Fructose, Glucose, Flavanoids and Tannins and Sterols and Phenolic compounds and fatty acids in the fruit. The quantity of elements (µg/g) in the fruit pulp powder was estimated by elemental analysis. The result shows Mn-53.5 and Zn - 46.2 were the major contents. While Pd- 14.3, Cu- 7.5 and Cr- 4.9 were minor contents. This study provided the pharmacognostical profile used to differentiate the other similar looking fruit from other ones of this genus.
Ragunathan Muthuswamy and R Senthamarai
EManuscript Technologies
Aim & Background: Resin of Canarium strictum Roxb., is an imperative commodity in traditional medicine in South and South East Asia. The current study aims to establish the quality control parameters for the bark as it secreted more useful resin. Methods: Anatomical studies and physiochemical evaluation of the bark was carried out according to the standard procedure was given in WHO/QCMMP guidelines and Indian Ayurvedic Pharmacopoeia. The anatomical studies of tissues were taken as photographs with different magnifications by using Nikon lab photo 2 microscopic Unit. The elemental analysis was done by using Perkin Elmer 5000 an atomic absorption spectrophotometer. Results: The different cell components were studied and measured quantitatively. The calcium oxalate prismatic crystals were estimated about 10×10 or 10×5µm in size. The sclereids were very long of unlimited length and 10µm in thickness. The long narrow lignified fibers has been found and estimated about 210–260µm long and about 10µm thick. The height of the ray is up to 350µm in height and 60µm in breadth. The physiochemical parameters such as total ash and acid insoluble ash (5.52% w/w, 2.66% w/w, respectively), extractive values (aqueous 4.55% w/w and alcoholic 6.05% w/w), foreign organic matter (2.4%) and loss on drying (7.09% w/w) were also estimated. An elemental analysis result shows the quantity of elements (µg/g) were present in the bark powder. Among the elements Mn-73.6, Cu-65.4, Cr-49.5 were major contents, while Pd-25.6 and Zn-35.4 were the minor contents. Conclusion: The current study report will be unique finger print for microscopical evaluation of bark of this tree and also used to differentiate the plant species among Canarium L.
Muthuswamy Ragunathan, Hawi tadesse, and Rebecca tujuba
EManuscript Technologies
A cross-sectional study pertaining to the practices and perceptions of modern and traditional health practitioners on Traditional Medicine (TM) was carried out from February 25 to April 4, 2008. The results of the study showed that almost all the practitioners in both systems expressed their willingness to collaborate among each other to promote the positive elements of TM. As traditional healing knowledge is still being handed over from one generation to the next, mainly through word of mouth, which will lead to distortion or a total demise of the original knowledge, this report indicates the urgency to document the same. Moreover, the report also implies the need for educating and training the practitioners of the two systems. More also has to be done to create a discussion forum for both modern and TM practitioners, to enable them to share their knowledge. Government support for promotion and development of TM should be considered as a goal to be seriously pursued. The government should also contribute by helping them financially and by arranging training and education for the improvement of the healthcare system given to the public.