Rodrigo Iturriaga

@uautonoma.cl

Instituto de Ciencias Biomedicas, Facultad Ciencias de la Salud.
Universidad Autonoma de Chile

Rodrigo Iturriaga


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https://researchid.co/riturriaga

RESEARCH, TEACHING, or OTHER INTERESTS

Neuroscience, Physiology, Physiology (medical)
5563

Scholar Citations

43

Scholar h-index

111

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Hypoxic development down-regulates endothelial Piezo1 via HIF1-α signaling and impairs Piezo1-mediated vasorelaxation
    GA Arenas, ALK Cochrane, E Peñaloza, AA Paz, M Carrasco, R Iturriaga, ...
    Clinical Science 140 (4), 493-507 , 2026
    2026
  • Chemogenetic inhibition of the carotid bodies blunts hind-limb suspension microgravity-induced muscle alterations in rats
    DC Andrade, C Salazar-Ardiles, C Toledo, J Bueno, AP Cabrera, ...
    American Journal of Physiology-Lung Cellular and Molecular Physiology 330 (2 … , 2026
    2026
  • Carotid Body Chemoreceptors: from Mountain to Space
    DC Andrade, C Salazar-Ardiles, B García-Ordenes, J Bueno, ...
    Physiology , 2026
    2026
  • Chronic hypoxia‐induced carotid body hypertonicity: Establishing ‘base cAMP’in the search for therapies
    K D O'Halloran, R Iturriaga, A Rocher
    The Journal of Physiology 604 (1), 14 , 2025
    2025
  • Physiological Differences Underlying Divergent Hypoxia Responses and Altitude Adaptations in Humans, Rats and Mice
    J Burtscher, RT Mallet, A Sah, M Gassmann, M Burtscher, R Iturriaga
    Comprehensive Physiology 15 (6), e70077 , 2025
    2025
    Citations: 5
  • The carotid body mediates peak oxygen uptake during maximal physical exertion in rats
    DC Andrade, C Salazar‐Ardiles, C Toledo, C Alvarez, E Díaz‐Jara, ...
    The Journal of Physiology 603 (22), 6859-6880 , 2025
    2025
    Citations: 5
  • Reactive oxidative species in carotid body chemoreception: Their role in oxygen sensing and cardiorespiratory alterations induced by chronic intermittent hypoxia
    R Iturriaga, HS Diaz
    Antioxidants 14 (6), 675 , 2025
    2025
    Citations: 6
  • Contribution of the carotid body to the cardiorespiratory and autonomic alterations induced by chronic intermittent hypoxia
    R Iturriaga
    Physiology 40 (S1), 0549 , 2025
    2025
  • Carotid bodies mediate glial cell activation and neuroinflammation in the NTS following long-term intermittent hypoxia: role in cardiorespiratory dysfunction
    K Pereyra, E Diaz-Jara, I Bernal-Santander, S Vicencio, R Del Rio, ...
    American Journal of Physiology-Lung Cellular and Molecular Physiology , 2025
    2025
    Citations: 12
  • Carotid body ablation reduces hypertension following long-term intermittent hypoxia by regulating brainstem glial cell activation
    R Iturriaga, K Pereyra, S Vicencio, I Bernal, E Diaz-Jara, R Del Rio
    Circulation 150 (Suppl_1), A4146116-A4146116 , 2024
    2024
  • Baroreflex and chemoreflex interaction in high-altitude exposure: possible role on exercise performance
    P Alvarez-Araos, S Jiménez, C Salazar-Ardiles, C Núñez-Espinosa, ...
    Frontiers in Physiology 15, 1422927 , 2024
    2024
    Citations: 14
  • Carotid body ablation restores astrocyte/microglia morphology in the NTS and reduces hypertension following long-term intermittent hypoxia
    R Iturriaga, K Pereyra, I Bernal, S Vicencio, E Diaz-Jara, R Del Rio
    Physiology 39 (S1), 2493 , 2024
    2024
  • Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease
    RM Lataro, F Brognara, R Iturriaga, JFR Paton
    Autonomic Neuroscience 251, 103137 , 2024
    2024
    Citations: 14
  • Carotid body contribution to the physio‐pathological consequences of intermittent hypoxia: Role of nitro‐oxidative stress and inflammation
    R Iturriaga
    The Journal of Physiology 601 (24), 5495-5507 , 2023
    2023
    Citations: 30
  • Chemogenetic inhibition of NTS astrocytes normalizes cardiac autonomic control and ameliorate hypertension during chronic intermittent hypoxia
    K Pereyra, A Las Heras, C Toledo, E Díaz-Jara, R Iturriaga, R Del Rio
    Biological research 56 (1), 57 , 2023
    2023
    Citations: 10
  • Transcriptional profiling of human endothelial cells unveils PIEZO1 and mechanosensitive gene regulation by prooxidant and inflammatory inputs
    GA Arenas, JG Valenzuela, E Peñaloza, AA Paz, R Iturriaga, CG Saez, ...
    Antioxidants 12 (10), 1874 , 2023
    2023
    Citations: 15
  • Carotid body ablation reduced the hypertension and the astrocyte activation in the nts induced by long-term exposure to chronic intermittent hypoxia
    R Iturriaga, K Pereyra, A Las Heras, E Diaz-Jara, R Del Rio
    IBRO Neuroscience Reports 15, S689-S690 , 2023
    2023
    Citations: 1
  • Remodeling and Pulmonary Hypertension Induced by Intermittent Hypoxia Is
    R Iturriaga, S Castillo-Galán
    Arterial Chemoreceptors: Mal (adaptive) Responses: O2 Dependent and … , 2023
    2023
  • Sympathetic and electrochemical skin responses in the assessment of sudomotor function: a comparative study
    J Idiaquez, JC Casar, R Fadic, R Iturriaga
    Neurophysiologie Clinique 53 (2), 102840 , 2023
    2023
    Citations: 13
  • Hyperhidrosis in sleep disorders–A narrative review of mechanisms and clinical significance
    J Idiaquez, JC Casar, ES Arnardottir, E August, J Santin, R Iturriaga
    Journal of sleep research 32 (1), e13660 , 2023
    2023
    Citations: 19

MOST CITED SCHOLAR PUBLICATIONS

  • Chronic intermittent hypoxia enhances cat chemosensory and ventilatory responses to hypoxia
    S Rey, RD Rio, J Alcayaga, R Iturriaga
    The Journal of physiology 560 (2), 577-586 , 2004
    2004
    Citations: 250
  • Neurotransmission in the carotid body: transmitters and modulators between glomus cells and petrosal ganglion nerve terminals
    R Iturriaga, J Alcayaga
    Brain Research Reviews 47 (1-3), 46-53 , 2004
    2004
    Citations: 247
  • Carotid body chemoreceptors: physiology, pathology, and implications for health and disease
    R Iturriaga, J Alcayaga, MW Chapleau, VK Somers
    Physiological reviews 101 (3), 1177-1235 , 2021
    2021
    Citations: 227
  • Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link
    R Del Rio, EA Moya, R Iturriaga
    European Respiratory Journal 36 (1), 143-150 , 2010
    2010
    Citations: 175
  • Carotid body inflammation and cardiorespiratory alterations in intermittent hypoxia
    R Del Rio, EA Moya, MJ Parga, C Madrid, R Iturriaga
    European Respiratory Journal 39 (6), 1492-1500 , 2012
    2012
    Citations: 148
  • Carotid body ablation abrogates hypertension and autonomic alterations induced by intermittent hypoxia in rats
    R Del Rio, DC Andrade, C Lucero, P Arias, R Iturriaga
    Hypertension 68 (2), 436-445 , 2016
    2016
    Citations: 145
  • Carotid body chemoreceptors, sympathetic neural activation, and cardiometabolic disease
    R Iturriaga, R Del Rio, J Idiaquez, VK Somers
    Biological research 49 (1), 13 , 2016
    2016
    Citations: 122
  • Contribution of endothelin-1 to the enhanced carotid body chemosensory responses induced by chronic intermittent hypoxia
    S Rey, R Del Rio, R Iturriaga
    Brain research 1086 (1), 152-159 , 2006
    2006
    Citations: 119
  • Carotid body potentiation induced by intermittent hypoxia: implications for cardiorespiratory changes induced by sleep apnoea
    R Iturriaga, EA Moya, R Del Rio
    Clinical and Experimental Pharmacology and Physiology 36 (12), 1197-1204 , 2009
    2009
    Citations: 109
  • Differential expression of pro-inflammatory cytokines, endothelin-1 and nitric oxide synthases in the rat carotid body exposed to intermittent hypoxia
    R Del Rio, EA Moya, R Iturriaga
    Brain research 1395, 74-85 , 2011
    2011
    Citations: 106
  • Contribution of in vivo microvascular PO2 in the cat carotid body chemotransduction
    S Lahiri, WL Rumsey, DF Wilson, R Iturriaga
    Journal of Applied Physiology 75 (3), 1035-1043 , 1993
    1993
    Citations: 95
  • Chronic hypoxia induces the activation of the Wnt/β-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1ΔE9 transgenic mice in vivo
    L Varela-Nallar, M Rojas-Abalos, AC Abbott, EA Moya, R Iturriaga, ...
    Frontiers in Cellular Neuroscience 8, 17 , 2014
    2014
    Citations: 83
  • In vitro perfused-superfused cat carotid body for physiological and pharmacological studies
    R Iturriaga, WL Rumsey, A Mokashi, D Spergel, DF Wilson, S Lahiri
    Journal of Applied Physiology 70 (3), 1393-1400 , 1991
    1991
    Citations: 83
  • Carbonic anhydrase and chemoreception in the cat carotid body
    R Iturriaga, S Lahiri, A Mokashi
    American Journal of Physiology-Cell Physiology 261 (4), C565-C573 , 1991
    1991
    Citations: 81
  • CO reveals dual mechanisms of O2 chemoreception in the cat carotid body
    S Lahiri, R Iturriaga, A Mokashi, DK Ray, D Chugh
    Respiration physiology 94 (2), 227-240 , 1993
    1993
    Citations: 77
  • Translating carotid body function into clinical medicine
    R Iturriaga
    The Journal of Physiology 596 (15), 3067-3077 , 2018
    2018
    Citations: 75
  • Inflammation and oxidative stress during intermittent hypoxia: the impact on chemoreception
    R Iturriaga, EA Moya, R Del Rio
    Experimental Physiology 100 (2), 149-155 , 2015
    2015
    Citations: 75
  • Enhanced carotid body chemosensory activity and the cardiovascular alterations induced by intermittent hypoxia
    R Iturriaga, DC Andrade, R Del Rio
    Frontiers in physiology 5, 468 , 2014
    2014
    Citations: 75
  • Electrical signaling, stomatal conductance, ABA and ethylene content in avocado trees in response to root hypoxia
    PM Gil, L Gurovich, B Schaffer, N García, R Iturriaga
    Plant Signaling & Behavior 4 (2), 100-108 , 2009
    2009
    Citations: 75
  • ACh and ATP mediate excitatory transmission in cat carotid identified chemoreceptor units in vitro
    R Varas, J Alcayaga, R Iturriaga
    Brain research 988 (1-2), 154-163 , 2003
    2003
    Citations: 75