Joao Manuel Cunha Rodrigues

@cqm.uma.pt

- Departamento de Química/Faculdade de Ciências Exactas e da Engenharia - Centro de Química da Madeira
Universidade da Madeira

Joao Manuel Cunha Rodrigues


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https://researchid.co/rodriguesjmcr
134

Scopus Publications

8737

Scholar Citations

46

Scholar h-index

98

Scholar i10-index

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

  • Hybrid dextran/fibronectin nanogels for brain-targeted mitophagy inducer delivery to alleviate neuroinflammation and neuronal loss of Parkinson's disease
    M Qin, H Sun, Y Ji, Z Li, C Ni, Z Wang, D Maciel, J Rodrigues, X Shi, ...
    Carbohydrate Polymers, 125410 , 2026
    2026
  • Biocompatible thermal shape-memory poly (lactide-co-trimethylene carbonate) elastomers for cell culture scaffold application
    S Zhang, X Li, D Zhou, W Luo, R He, J Rodrigues, H Tomás, R Sheng, ...
    Journal of Materials Chemistry B , 2026
    2026
  • Tocopherol–Doxorubicin Conjugate as a Lipid–Prodrug: Synthetic Methods, Self-Assembly, Breast Cancer Cell Inhibition, and Theoretical Analysis
    L Caires, D Maciel, R Castro, M Gonçalves, JAM Pereira, JS Câmara, ...
    Chemistry Proceedings 18 (1), 118 , 2025
    2025
  • Natural alkaloids from Dicranostigma leptopodum (Maxim.) Fedde and their G5. NHAc-PBA dendrimer-alkaloid complexes for targeting chemotherapy in breast …
    Y Tian, Z Wang, X Xu, Y Guo, Y Ma, Y Lu, M Shen, Y Geng, H Tomás, ...
    Natural Product Research 39 (15), 4279-4296 , 2025
    2025
    Citations: 2
  • PLLA–PEG/mPEG Copolymer with Improved Hydrophilicity, Crystallinity, and Biocompatibility: An In-Depth Study on the Crystallization Kinetics
    R Lian, D Zhou, L Xiao, J Rodrigues, R Sheng, Z Bai, Y Li, C Liu
    ACS Applied Materials & Interfaces 17 (20), 30067-30080 , 2025
    2025
    Citations: 7
  • Recent advances in nanomedicines loaded with MicroRNAs for cancer demethylation therapy
    Q Tan, J Wang, Y Tian, J Rodrigues, Z Li, X Shi, M Shen
    Precision Medicine and Engineering 2 (1), 100023 , 2025
    2025
    Citations: 1
  • Nanomedicines for the treatment of ischemic stroke: an overview of recent advances
    S Geng, C Zhang, J Rodrigues, D Shcharbin, S Mignani, JP Majoral, ...
    Precision Medicine and Engineering 2 (1), 100022 , 2025
    2025
    Citations: 2
  • Stabilization of metal-doped magnesium oxide nanoparticles with PAMAM dendrimers to improve alpha-amylase enzyme inhibition
    J Jeevanandam, M Gonçalves, R Castro, J Gallo, M Bañobre-López, ...
    Materials Today Bio, 101520 , 2025
    2025
    Citations: 6
  • Conjugation of PDLA onto MgO microspheres: comparison between solution grafting and melt grafting methods
    W Yu, D Zhou, F Liu, X Li, L Xiao, M Rafique, Z Li, J Rodrigues, R Sheng, ...
    Journal of Materials Chemistry B 13 (8), 2674-2681 , 2025
    2025
    Citations: 1
  • Bioinspired hybrid DNA/dendrimer-based films with supramolecular chirality
    R Castro, PL Granja, J Rodrigues, AP Pêgo, H Tomás
    Journal of Materials Chemistry B 13 (15), 4671-4680 , 2025
    2025
  • Gelatin-based ballistic gel formulated with phytosynthesized nanocellulose from Arundo donax for alpha-amylase enzyme inhibition activity
    J Jeevanandam, R Castro, J Rodrigues
    Carbohydrate Polymer Technologies and Applications 8, 100575 , 2024
    2024
    Citations: 1
  • Recent advances in nanogels composed of dendrimers to tackle cancer
    X Xiao, Y Gao, I Stoikov, D Shcharbin, J Rodrigues, M Shen, X Shi
    Nanomedicine 19 (13), 1117-1121 , 2024
    2024
    Citations: 3
  • Sustainable synthesis of bionanomaterials using non-native plant extracts for maintaining ecological balance: A computational bibliography analysis
    J Jeevanandam, J Rodrigues
    Journal of Environmental Management 358, 120892 , 2024
    2024
    Citations: 11
  • Poly (alkylideneamine) Dendrimer Nanogels Codeliver Drug and Nucleotide To Alleviate Anticancer Drug Resistance through Immunomodulation
    Y Gao, Z Ouyang, G Li, Q Yu, W Dai, J Rodrigues, A Pich, ...
    ACS Materials Letters 6 (2), 517-527 , 2024
    2024
    Citations: 11
  • Blood–brain barrier-crossing dendrimers for glioma theranostics
    J Wang, Z Wang, G Zhang, J Rodrigues, H Tomás, X Shi, M Shen
    Biomaterials Science 12 (6), 1346-1356 , 2024
    2024
    Citations: 27
  • Smart stimuli-responsive strategies for titanium implant functionalization in bone regeneration and therapeutics
    J Zhang, Y Zhuang, R Sheng, H Tomás, J Rodrigues, G Yuan, X Wang, ...
    Materials Horizons 11 (1), 12-36 , 2024
    2024
    Citations: 93
  • Cellulose-based bionanocomposites: Synthesis, properties, and applications
    J Jeevanandam, J Rodrigues, S Pan, MK Danquah
    Advances in Bionanocomposites, 191-210 , 2024
    2024
    Citations: 9
  • Carbon dots and dendrimers nanohybrids: From synthesis to applications
    IJ Martins, H Tomás, J Rodrigues
    Materials Today Chemistry 32, 101662 , 2023
    2023
    Citations: 9
  • Redox-Responsive Dendrimer Nanogels Enable Ultrasound-Enhanced Chemoimmunotherapy of Pancreatic Cancer via Endoplasmic Reticulum Stress Amplification and Macrophage Polarization
    G Zhang, M Zhan, C Zhang, Z Wang, H Sun, Y Tao, Q Shi, M He, H Wang, ...
    Advanced Science, 2301759 , 2023
    2023
    Citations: 55
  • State-of-the-art rational nanodesign: from screening to theranostics and from bench to clinic
    A Fernandez-Fernandez, R Manchanda, JM Cunha Rodrigues, Y Tang
    Frontiers in Pharmacology 14, 1210185 , 2023
    2023
    Citations: 1

MOST CITED SCHOLAR PUBLICATIONS

  • Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications
    Y Li, J Rodrigues, H Tomás
    Chem. Soc. Rev. 41 (6), 2193-2221 , 2012
    2012
    Citations: 1664
  • Biodegradable Polymer Nanogels for Drug/Nucleic Acid Delivery
    Y Li, D Maciel, J Rodrigues, X Shi, H Tomás
    Chemical Reviews 115, 8564–8608 , 2015
    2015
    Citations: 546
  • Green approaches for the synthesis of metal and metal oxide nanoparticles using microbial and plant extracts
    J Jeevanandam, SF Kiew, SB Ansah, SY Lau, A Barhoum, MK Danquah, ...
    Nanoscale 14, 2525-2533 , 2022
    2022
    Citations: 508
  • Laponite®: A key nanoplatform for biomedical applications?
    H Tomás, CS Alves, J Rodrigues
    Nanomedicine: Nanotechnology, Biology and Medicine 14, 2407-2420 , 2018
    2018
    Citations: 397
  • Functionalization of poly (amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells
    JL Santos, H Oliveira, D Pandita, J Rodrigues, AP Pêgo, PL Granja, ...
    Journal of Controlled Release 144 (1), 55-64 , 2010
    2010
    Citations: 245
  • Dendrimers in combination with natural products and analogues as anti-cancer agents
    S Mignani, J Rodrigues, H Tomas, M Zablocka, X Shi, AM Caminade, ...
    Chemical Society Reviews 47, 514-532 , 2018
    2018
    Citations: 231
  • Redox-responsive alginate nanogels with enhanced anticancer cytotoxicity
    D Maciel, P Figueira, S Xiao, D Hu, X Shi, J Rodrigues, H Tomás, Y Li
    Biomacromolecules 14, 3140–3146 , 2013
    2013
    Citations: 186
  • Non-viral gene delivery to mesenchymal stem cells: methods, strategies and application in bone tissue engineering and regeneration
    J L. Santos, D Pandita, J Rodrigues, A P. Pego, P L. Granja, H Tomas
    Current gene therapy 11 (1), 46-57 , 2011
    2011
    Citations: 179
  • Polysaccharide-based nanomedicines for cancer immunotherapy: A review
    Y Zeng, Y Xiang, R Sheng, H Tomás, J Rodrigues, Z Gu, H Zhang, ...
    Bioactive Materials 6 (10), 3358-3382 , 2021
    2021
    Citations: 165
  • Thermo/redox/pH-triple sensitive poly (N-isopropylacrylamide-co-acrylic acid) nanogels for anticancer drug delivery
    Y Zhan, M Gonçalves, P Yi, D Capelo, Y Zhang, J Rodrigues, C Liu, ...
    Journal of Materials Chemistry B 3 (20), 4221-4230 , 2015
    2015
    Citations: 155
  • Present drug-likeness filters in medicinal chemistry during the hit and lead optimization process: how far can they be simplified?
    S Mignani, J Rodrigues, H Tomas, R Jalal, PP Singh, JP Majoral, ...
    Drug Discovery Today 23, 605-615 , 2018
    2018
    Citations: 145
  • Receptor-mediated gene delivery using PAMAM dendrimers conjugated with peptides recognized by mesenchymal stem cells
    JL Santos, D Pandita, J Rodrigues, AP Pêgo, PL Granja, G Balian, ...
    Molecular pharmaceutics 7 (3), 763-774 , 2010
    2010
    Citations: 142
  • RGD peptide-modified multifunctional dendrimer platform for drug encapsulation and targeted inhibition of cancer cells
    X He, CS Alves, N Oliveira, J Rodrigues, J Zhu, I Bányai, H Tomás, X Shi
    Colloids and Surfaces B: Biointerfaces 125, 82-89 , 2015
    2015
    Citations: 129
  • pH-sensitive Laponite®/doxorubicin/alginate nanohybrids with improved anticancer efficacy
    M Gonçalves, P Figueira, D Maciel, J Rodrigues, X Qu, C Liu, H Tomás, ...
    Acta biomaterialia 10, 300-307 , 2014
    2014
    Citations: 123
  • Why and how have drug discovery strategies in pharma changed? What are the new mindsets?
    S Mignani, S Huber, H Tomás, J Rodrigues, JP Majoral
    Drug discovery today 21 (2), 239-249 , 2016
    2016
    Citations: 119
  • PAMAM dendrimers: blood-brain barrier transport and neuronal uptake after focal brain ischemia
    SD Santos, M Xavier, DM Leite, DA Moreira, B Custódio, M Torrado, ...
    Journal of Controlled Release 291, 65-79 , 2018
    2018
    Citations: 115
  • Gene Delivery into Mesenchymal Stem Cells: A Biomimetic Approach Using RGD Nanoclusters Based on Poly (amidoamine) Dendrimers
    D Pandita, JL Santos, J Rodrigues, AP Pêgo, PL Granja, H Tomás
    Biomacromolecules 12 (2), 472-481 , 2011
    2011
    Citations: 115
  • Multifunctional Dendrimer-Entrapped Gold Nanoparticles Conjugated with Doxorubicin for pH-Responsive Drug Delivery and Targeted Computed Tomography Imaging
    J Zhu, G Wang, CS Alves, H Tomás, Z Xiong, M Shen, J Rodrigues, S X.
    Langmuir 34 (41), 12428–12435 , 2018
    2018
    Citations: 112
  • Synthesis approach-dependent antiviral properties of silver nanoparticles and nanocomposites
    J Jeevanandam, S Krishnan, YS Hii, S Pan, YS Chan, C Acquah, ...
    Journal of Nanostructure in Chemistry 12 (5), 809-831 , 2022
    2022
    Citations: 109
  • Amphiphilic polymer-mediated formation of laponite-based nanohybrids with robust stability and pH sensitivity for anticancer drug delivery
    G Wang, D Maciel, Y Wu, J Rodrigues, X Shi, Y Yuan, C Liu, H Tomás, ...
    ACS applied materials & interfaces 6 (19), 16687-16695 , 2014
    2014
    Citations: 105