Rozangela Curi Pedrosa

@ufsc.br

Department of Biochemistry
Universidade Federal de Santa Catarina

RESEARCH, TEACHING, or OTHER INTERESTS

Biochemistry, Structural Biology, Cancer Research, Drug Discovery
6829

Scholar Citations

46

Scholar h-index

99

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Pheomelanin and PEG Coatings on Superparamagnetic Fe 3 O 4 Nanoparticles: Reduced T 2 in MRI for Early Cancer Diagnosis
    ESA Ricardo, JM Beltrame, RC Pedrosa, BB Pereira Ribeiro, D Salvador, ...
    ACS Applied Nano Materials , 2026
    2026
  • EFFECTS OF PYRIPROXYFEN EXPOSURE ON SPERMATOGENIC CELLS IN DANIO RERIO
    BA Zaniboni, VS de Oliveira, GAA Leite, VMA de Souza Grinevicius, ...
    IV Congresso Latino-americano de Toxicologia Clínico-laboratorial 5 , 2025
    2025
  • Pyriproxyfen Disrupts the Ongoing Spermatogenesis Wave in Danio rerio Potentially Mediated by Voltage‐Dependent Calcium Channels and Protein Kinase C
    BA Zaniboni, VS Oliveira, GAA Leite, VMAS Grinevicius, RC Pedrosa, ...
    Journal of Applied Toxicology 45 (9), 1705-1719 , 2025
    2025
    Citations: 1
  • Allium cepa exposed to Nativo® fungicide with and without swine liver enzyme biotransformation: A comparative genotoxicity study
    FL Dalpiaz, R Laçoli, RC Pedrosa, JR Santin, R Corrêa, TM Wagner, ...
    Chemosphere 373, 144149 , 2025
    2025
  • Doxorubicin and 4-nitrochalcone loaded in beeswax-based nanostructured lipid carriers: In vitro antitumoral screening and evaluation of synergistic effect on HepG-2 cells
    AP Cordeiro, PE Feuser, PHH Araújo, DC Dos Santos, F Ourique, ...
    International Journal of Pharmaceutics 666, 124788 , 2024
    2024
    Citations: 4
  • Oncogenic PI3KT/Akt/mTOR pathway alterations, ROS homeostasis, targeted cancer therapy and drug resistance
    RC Pedrosa, KB Felipe, D Wilhelm Filho
    Frontiers in Oncology 14, 1372376 , 2024
    2024
    Citations: 5
  • Glyphosate-induced glioblastoma cell proliferation: Unraveling the interplay of oxidative, inflammatory, proliferative, and survival signaling pathways
    CD Bianco, F Ourique, DC Dos Santos, RC Pedrosa, MR Kviecisnki, ...
    Environmental Pollution 338, 122695 , 2023
    2023
    Citations: 21
  • Lippia sidoides essential oil (Verbenaceae) improves inflammatory response and histological condition in Danio rerio
    L Cardoso, MS Owatari, FCM Chaves, WE Furtado, LA Honorato, ...
    Aquaculture International 31 (5), 2665-2685 , 2023
    2023
    Citations: 7
  • IN SILICO PREDICTIONS OF 2-PHENYL-3-(4-DIMETHYLAMINOPHENYL) QUINOXALINE ACTIVITY AND AKT1 INHIBITION
    RC Zeferino, JK Ramos, HD de Salles, V Grinevicius, P Moreira, D Lousa, ...
    XXIX International Symposium" Bioinformatics and Computer-Aided Drug … , 2023
    2023
  • IMMUNOMODULATORY ACTIVITY OF BENZNIDAZOLE IN EHRLICH ASCITES CARCINOMA IN SILICO AND IN VIVO
    R Zeferino, V Grineviciu, N Mota, RC Pedrosa
    XXIX International Symposium" Bioinformatics and Computer-Aided Drug … , 2023
    2023
  • Docking and molecular dynamics predicted B-DNA and dihydropyrimidinone selenoesters interactions elucidating antiproliferative effects on breast adenocarcinoma cells
    JC Benassi, FAR Barbosa, G Candiotto, VMAS Grinevicius, DW Filho, ...
    Journal of Biomolecular Structure and Dynamics 40 (18), 8261-8273 , 2022
    2022
    Citations: 9
  • Chemical profile, antimicrobial potential, and antiaggregant activity of supercritical fluid extract from Agaricus bisporus
    SS Weber, ACS de Souza, DCL Soares, CC Lima, ACR de Moraes, ...
    Chemical Papers 76 (10), 6205-6214 , 2022
    2022
    Citations: 9
  • IP‐Se‐06, a Selenylated Imidazo[1,2‐ a ]pyridine, Modulates Intracellular Redox State and Causes Akt/mTOR/HIF‐1 α and MAPK Signaling Inhibition, Promoting …
    DC Dos Santos, J Rafique, S Saba, VMAS Grinevicius, DW Filho, ...
    Oxidative Medicine and Cellular Longevity 2022 (1), 3710449 , 2022
    2022
    Citations: 38
  • The toxicity of Aspidosperma subincanum to MCF7 cells is related to modulation of oxidative status and proinflammatory pathways
    AF Santos, NSRS Mota, EM Schiefer, RS da Cunha, AM Junkert, ...
    Journal of ethnopharmacology 281, 114512 , 2021
    2021
    Citations: 2
  • Prevention of ferroptosis in acute scenarios: an in vitro study with classic and novel anti-ferroptotic compounds
    AA Naime, FAR Barbosa, DC Bueno, R Curi Pedrosa, RFS Canto, D Colle, ...
    Free Radical Research 55 (11-12), 1062-1079 , 2021
    2021
    Citations: 9
  • Traditional use of Dillenia indica L. fruits with anti-inflammatory purposes by participants of the elderly and pastoral healthcare groups in the southern region of …
    MR Kviecinski, LF Nunes, SE Felisberto, FS Fernandes, IMB David, ...
    2021
  • Estradiol and 1α, 25 (OH) 2 vitamin D3 share plasma membrane downstream signal transduction through calcium influx and genomic activation in immature rat testis
    AP Zanatta, R Gonçalves, FO da Silva, RC Pedrosa, L Zanatta, ...
    Theriogenology 172, 36-46 , 2021
    2021
    Citations: 5
  • Novel dihydropyrimidinone-derived selenoesters as potential cytotoxic agents to human hepatocellular carcinoma: molecular docking and DNA fragmentation
    JC Benassi, FAR Barbosa, VMAS Grinevicius, F Ourique, D Coelho, ...
    Anti-Cancer Agents in Medicinal Chemistry-Anti-Cancer Agents) 21 (6), 703-715 , 2021
    2021
    Citations: 17
  • Apoptosis oxidative damage‐mediated and antiproliferative effect of selenylated imidazo[1,2‐ a ]pyridines on hepatocellular carcinoma HepG2 cells and in vivo
    DC Dos Santos, J Rafique, S Saba, GM Almeida, T Siminski, C Pádua, ...
    Journal of Biochemical and Molecular Toxicology 35 (3), e22663 , 2021
    2021
    Citations: 37
  • The widely used antihelmintic drug albendazole is a potent inducer of loss of heterozygosity
    LSEP Will Castro, W Pieters, MF Alemdehy, MA Aslam, OA Buoninfante, ...
    Frontiers in pharmacology 12, 596535 , 2021
    2021
    Citations: 10

MOST CITED SCHOLAR PUBLICATIONS

  • Fármacos e fitoterápicos: a necessidade do desenvolvimento da indústria de fitoterápicos e fitofármacos no Brasil
    RA Yunes, RC Pedrosa, V Cechinel Filho
    Química nova 24 (1), 147-152 , 2001
    2001
    Citations: 395
  • Antioxidant and antimicrobial activities of shiitake (Lentinula edodes) extracts obtained by organic solvents and supercritical fluids
    CSG Kitzberger, A Smânia Jr, RC Pedrosa, SRS Ferreira
    Journal of food engineering 80 (2), 631-638 , 2007
    2007
    Citations: 311
  • Oxidative stress in the mussel Mytella guyanensis from polluted mangroves on Santa Catarina Island, Brazil
    MA Torres, CP Testa, C Gáspari, MB Masutti, CMN Panitz, ...
    Marine pollution bulletin 44 (9), 923-932 , 2002
    2002
    Citations: 286
  • Free radical scavenging of grape pomace extracts from Cabernet sauvingnon (Vitis vinifera)
    LMAS de Campos, FV Leimann, RC Pedrosa, SRS Ferreira
    Bioresource Technology 99 (17), 8413-8420 , 2008
    2008
    Citations: 255
  • Effect of different oxygen tensions on weight gain, feed conversion, and antioxidant status in piapara, Leporinus elongatus (Valenciennes, 1847)
    D Wilhelm Filho, MA Torres, E Zaniboni-Filho, RC Pedrosa
    Aquaculture 244 (1-4), 349-357 , 2005
    2005
    Citations: 237
  • Study of the antitumor potential of Bidens pilosa (Asteraceae) used in Brazilian folk medicine
    MR Kviecinski, KB Felipe, T Schoenfelder, LP de Lemos Wiese, MH Rossi, ...
    Journal of ethnopharmacology 117 (1), 69-75 , 2008
    2008
    Citations: 223
  • Influence of season and pollution on the antioxidant defenses of the cichlid fish acará (Geophagus brasiliensis)
    D Wilhelm Filho, MA Torres, TB Tribess, RC Pedrosa, CHL Soares
    Brazilian Journal of Medical and Biological Research 34 (6), 719-726 , 2001
    2001
    Citations: 220
  • Effect of crosslinking agents on chitosan microspheres in controlled release of diclofenac sodium
    VL Gonçalves, M Laranjeira, VT Fávere, RC Pedrosa
    Polímeros 15, 6-12 , 2005
    2005
    Citations: 212
  • Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture.
    R Curi-Pedrosa, M Daujat, L Pichard, JC Ourlin, P Clair, L Gervot, P Lesca, ...
    The Journal of pharmacology and experimental therapeutics 269 (1), 384-392 , 1994
    1994
    Citations: 187
  • Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents
    J Benites, JA Valderrama, K Bettega, RC Pedrosa, PB Calderon, J Verrax
    European journal of medicinal chemistry 45 (12), 6052-6057 , 2010
    2010
    Citations: 155
  • Protective properties of butanolic extract of the Calendula officinalis L.(marigold) against lipid peroxidation of rat liver microsomes and action as free radical …
    CAS Cordova, IR Siqueira, CA Netto, RA Yunes, AM Volpato, VC Filho, ...
    Redox report 7 (2), 95-102 , 2002
    2002
    Citations: 130
  • Markers of genotoxicity and oxidative stress in farmers exposed to pesticides
    CH Jacobsen-Pereira, CR Dos Santos, FT Maraslis, L Pimentel, AJL Feijó, ...
    Ecotoxicology and environmental safety 148, 177-183 , 2018
    2018
    Citations: 110
  • Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damage in DNA leading to cell cycle arrest and apoptosis in cancer cells
    VMA de Souza Grinevicius, MR Kviecinski, NSRS Mota, F Ourique, ...
    Journal of ethnopharmacology 189, 139-147 , 2016
    2016
    Citations: 108
  • Proanthocyanidin profile and antioxidant capacity of Brazilian Vitis vinifera red wines
    EF Gris, F Mattivi, EA Ferreira, U Vrhovsek, RC Pedrosa, ...
    Food Chemistry 126 (1), 213-220 , 2011
    2011
    Citations: 107
  • Composição química e atividades biológicas das folhas de Cynara scolymus L.(alcachofra) cultivada no Brasil
    VF Noldin, V Cechinel Filho, FD Monache, JC Benassi, IL Christmann, ...
    Química nova 26 (3), 331-334 , 2003
    2003
    Citations: 106
  • Nanoparticles made from xyloglucan-block-polycaprolactone copolymers: Safety assessment for drug delivery
    L Mazzarino, G Loch-Neckel, L dos Santos Bubniak, F Ourique, I Otsuka, ...
    Toxicological Sciences 147 (1), 104-115 , 2015
    2015
    Citations: 100
  • Albendazole as a promising molecule for tumor control
    L Castro, MR Kviecinski, F Ourique, EB Parisotto, V Grinevicius, ...
    Redox biology 10, 90-99 , 2016
    2016
    Citations: 94
  • Hsp90 cleavage by an oxidative stress leads to its client proteins degradation and cancer cell death
    R Beck, J Verrax, T Gonze, M Zappone, RC Pedrosa, H Taper, O Feron, ...
    Biochemical pharmacology 77 (3), 375-383 , 2009
    2009
    Citations: 92
  • In situ modulation of oxidative stress: a novel and efficient strategy to kill cancer cells
    J Verrax, RC Pedrosa, R Beck, N Dejeans, H Taper, PB Calderon
    Current medicinal chemistry 16 (15), 1821-1830 , 2009
    2009
    Citations: 91
  • Oxidative metabolism of lansoprazole by human liver cytochromes P450.
    L Pichard, R Curi-Pedrosa, C Bonfils, E Jacqz-Aigrain, J Domergue, ...
    Molecular pharmacology 47 (2), 410-418 , 1995
    1995
    Citations: 90