RAVINDRA KARADI

EDUCATION

M.Pharm in Pharmacognosy

RESEARCH INTERESTS

Screening of herbal drugs for their potential pharmacological and therapeutical applications

Scopus Publications

Statistical screening and optimization of the medium components for production of novel flavolipid biosurfactant by Flavobacterium sp. MTCC 2495




Screening of Careya arborea Roxb for their anticonvulsant properties in experimental animals
GulabS Shinde, RavindraV Karadi, AjayS Khedkar, PravinJ Dere, YuvarajD Mandavkar, and PallaviR Khalure
BRNSS Publication Hub



Screening of selected herbal plants for anti acne properties




Anti-inflammatory and anti-arthritic potential of aqueous and alcoholic extracts of Euphorbia antiquorum Linn




Protease from an Actinomycetes species: Production, optimization and characterization




Effect of Bauhinia variegata bark extract on blood glucose level in normal and alloxanised Diabetic rats




Antiurolithiatic property of moringa oleifera root bark
R.V. Karadi, M.B. Palkar, E.N. Gaviraj, N.B. Gadge, V.S. Mannur, and K.R. Alagawadi
Informa UK Limited
In spite of tremendous advances in the field of medicine, there is no truly satisfactory drug for the treatment of renal calculi. In the present study, the efficacy of the root bark of Moringa oleifera Lam. (Moringaceae) as an antiurolithiatic agent was investigated using an experimentally induced urolithiatic rat model. Hyperoxaluria was induced in rats using 0.75% ethylene glycol in water. Aqueous (AqE) (200 mg kg− 1 body weight) and alcoholic extracts (AlcE) (200 mg kg− 1 body weight) of the root bark of M. oleifera were given orally in curative and preventive regimens over a period of 28 days. Both the extracts significantly (P < 0.001) lowered the urinary excretion and kidney retention levels of oxalate, calcium and phosphate. Moreover, elevated serum levels of urea nitrogen, creatinine and uric acid were significantly (P < 0.001) reduced by the extracts. The results were comparable with the standard drug, cystone (750 mg kg− 1 body weight). The reduction of stone forming constituents in urine and their decreased kidney retention reduces the solubility product of crystallizing salts such as calcium oxalate and calcium phosphate, which could contribute to the antiurolithiatic property of root bark of M. oleifera.


Effect of Moringa oleifera Lam. root-wood on ethylene glycol induced urolithiasis in rats
Ravindra V. Karadi, Navneet B. Gadge, K.R. Alagawadi, and Rudraprabhu V. Savadi
Elsevier BV



Wound healing activity of Euphorbia hirta Linn.




Antiarthritic activity of extracts of Moringa oleifera Lam. roots




Antipyretic and wound healing activities of Moringa oleifera Lam. in rats
VI Hukkeri, CV Nagathan, RV Karadi, and BS Patil
OMICS Publishing Group
Qualitative chemical tests confirmed the presence of phytosterols, glycosides, tannins, and amino acids in the various leaf extracts of Moringa oleifera Lam., whereas its seed extracts showed the presence of phytosterols, glycosides, phenolic compounds, carbohydrates and amino acids. The ethanolic and ethyl acetate extracts of seeds showed significant antipyretic activity in rats, whereas ethyl acetate extract of dried leaves showed significant wound healing activity (10% extracts in the form of ointment) on excision, incision and dead space (granuloma) wound models in rats.


Hepatoprotective activity of fruit pulp of Annona reticulata Linn. in carbon tetrachloride induced toxicity




Comparative study of leaves and bark of Ailanthus excelsa Roxb. for hepatoprotective activity




Heptoprotective activity of bark of Balanites aegyptiaca Linn




Anti-inflammatory activity of leaves of Acacia farnesiana willd




Wound healing property of Eucalyptus globulus L. leaf extract'