Dr. Sagar Bag

Dr. Sagar Bag ( Former CSIR UGC NET SRF; DST-INSPIRE Fellow; University of Calcutta) is currently working as a Senior researcher. His research mainly focuses on different aspects of Genetics & Molecular Biological Techniques, Biophysical chemistry, Non-canonical DNA. Senior Researcher with a demonstrated history of working in the higher education institutes. Skilled in Biotechnology, Cancer Research, Animal handling, Life Sciences & Pharmaceutical research.

Multidisciplinary, Biochemistry, Genetics and Molecular Biology, Biophysics, Molecular Medicine

Research Publications in Highly reputed peer-reviewed Journals.

1. The Foundation for Medical Research
Dr. Kantilal J Sheth Memorial Building, 84-A, Dr RG Thadani Marg, Siddharth Nagar, Worli, Mumbai, Maharashtra 400018
2. Mahatma Gandhi Medical Advanced Research Institute (MGMARI)
Sri Balaji Vidyapeeth (Deemed to be University), SBV Campus Pillaiyarkuppam Pondicherry - 607 402. India
3. UGC-DAE Consortium for Scientific Research
Kolkata Centre
Sector III, LB-8, Bidhan Nagar, Kolkata 700 106.
UGC-DAE Consortium for Scientific Research is an autonomous institute of the University Grants Commission (UGC), India
4. Department of Chemistry, Jadavpur University, Kolkata 700 032, INDIA.

I-motif (IM) DNA structures represents among the most significant non-canonical nucleic acid configurations. IM forming DNA sequences are found in an array of vital genomic locations and are particularly frequent in the promoter islands of various oncogenes. Thus, IM DNA is a crucial candidate for anticancer medicines, therefore binding interactions between IM DNA and small molecular ligands such as flavonoids are critically important. Flavonoids therefore emerged as a suitable natural product-oriented antagonist for targeting IM DNA. The innovative spectroscopic as well as mechanical features of flavonoids and its specific affinity for selective IM may be useful for therapeutic applications and provide crucial insights for the design of compounds with remarkable medicinal properties. Flavonoids' pioneering unique features might be used in theranostics applications and drug development. The results we have found are very promising and for future drug designing flavonoid may be used as a base molecule by some modifications/appropriate tuning in their structure. Quercetin is also a very promising molecule that may be used in ligand-based drug development, which begins with a single ligand known to be powerful against a target. Effectiveness and other critical qualities are enhanced by developing relevant analogues based on structure-activity relationships.

1. Honorary Scientific member of American Chemical Society (ACS), USA, 2024 [ACS Membership ID:-33476729].
2. Honorary Scientific member of Royal Society of Chemistry (RSC), UK, 2024 [RSC Membership ID:-767611].
3. Prestigious Fellow of Scholars Academic and Scientific Society (FSASS), SAS Society, An International Society for Academic & Scientific Integration, with Membership ID-SAS/FSASS/748/2024; 2nd September, 2024; .
4. Dignitary Royal Fellow awarded “FRIOASD” by International Organization for Academic and Scientific Development.
5. Academic Peer Reviewer in the Scientific Reports (Nature), Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Computers in Biology and Medicine Journal, Elsevier, ScienceDirect (Impact ISSN: 0010-4825) [Reviewing 11 Research Articles].
6. Associate Editor in Frontiers in Biophysics.