Sravani Sana

@zibolab.web.unc.edu

Radiochemist/ Research Associate
Biomedical Research Imaging Center, University of North Carolina, Chapel Hill

RESEARCH, TEACHING, or OTHER INTERESTS

Chemistry, Organic Chemistry, Process Chemistry and Technology, Radiology, Nuclear Medicine and imaging
18

Scopus Publications

900

Scholar Citations

15

Scholar h-index

17

Scholar i10-index

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

  • Synthesis and Evaluation of Bispecific 64Cu—Radio conjugates for PET Imaging in Prostate Cancer Models
    S Sana, X Ma, W Zhao, S Cheng, X Wu, X Ni, Z Wu, Z Li
    Journal of Nuclear Medicine 66 (supplement 1), 252187-252187 , 2025
    2025
  • Synthesis and Evaluation of FAPI-Targeted 64Cu— Radioconjugates Containing Variable PEG Linkers for PET Imaging in U87 Cancer Models
    S Sana, X Ma, K Rakesh, W Zhao, Z Wu, Z Li
    Journal of Nuclear Medicine 65 (supplement 2), 242489-242489 , 2024
    2024
  • Synthesis and preclinical characterization of the 64Cu labeled TRPC5-targeting PET imaging probe for cancer
    X Ma, S Sana, Z Xing, Y Yu, W Zhao, Z Wu, Z Tu, Z Li
    Journal of Nuclear Medicine 65 (supplement 2), 242385-242385 , 2024
    2024
  • Hexafluoroisopropanol as a bioconjugation medium of ultrafast, tryptophan-selective catalysis
    M Nuruzzaman, BM Colella, CP Uzoewulu, AE Meo, EJ Gross, S Ishizawa, ...
    Journal of the American Chemical Society 146 (10), 6773-6783 , 2024
    2024
    Citations: 28
  • Visible-light-mediated photocatalytic sequential N-arylation: an eco-friendly synthetic route to unsymmetrical diarylamines and the imatinib drug
    S Sana, S Dastari, DS Reddy, R Tokala, M Sathish, R Sonti, ...
    Organic Chemistry Frontiers 10 (18), 4573-4580 , 2023
    2023
    Citations: 7
  • Sustainable photocatalytic C–H annulation of heteroarenes with sulfoxonium ylides: synthesis and photophysical properties of fused imidazo [1, 2-a] pyridine-based molecules
    S Sana, SR Dannarm, R Tokala, S Dastari, M Sathish, R Kumar, R Sonti, ...
    Organic Chemistry Frontiers 10 (19), 4800-4808 , 2023
    2023
    Citations: 15
  • Regioselective ortho ‐sulfonamidation: Exploration of Intrinsic Directing Property of β‐Carbolines and their Photophysical Studies
    D Bora, S Reddy Dannarm, S Elza John, S Sana, R Sonti, N Shankaraiah
    Asian Journal of Organic Chemistry 10 (12), 3384-3389 , 2021
    2021
    Citations: 17
  • Synthesis and biological evaluation of novel imidazo [1, 2-a] pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA …
    DK Sigalapalli, G Kiranmai, GP Devi, R Tokala, S Sana, C Tripura, ...
    Bioorganic & Medicinal Chemistry 43, 116277 , 2021
    2021
    Citations: 26
  • Cinnamide derived pyrimidine-benzimidazole hybrids as tubulin inhibitors: synthesis, in silico and cell growth inhibition studies
    S Sana, VG Reddy, TS Reddy, R Tokala, R Kumar, SK Bhargava, ...
    Bioorganic Chemistry 110, 104765 , 2021
    2021
    Citations: 76
  • Synthesis and preclinical evaluation of indole triazole conjugates as microtubule targeting agents that are effective against MCF-7 breast cancer cell lines
    V Yele, SKSS Pindiprolu, S Sana, D Ramamurty, JRK Madasi, ...
    Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal … , 2021
    2021
    Citations: 21
  • Palladium catalyzed C–C and C–N bond forming reactions: an update on the synthesis of pharmaceuticals from 2015–2020
    J Rayadurgam, S Sana, M Sasikumar, Q Gu
    Organic Chemistry Frontiers 8 (2), 384-414 , 2021
    2021
    Citations: 222
  • Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction
    R Tokala, S Mahajan, G Kiranmai, DK Sigalapalli, S Sana, SE John, ...
    Bioorganic Chemistry 106, 104481 , 2021
    2021
    Citations: 54
  • Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity
    R Tokala, S Sana, UJ Lakshmi, P Sankarana, DK Sigalapalli, N Gadewal, ...
    Bioorganic Chemistry 105, 104357 , 2020
    2020
    Citations: 43
  • Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect
    S Sana, VG Reddy, S Bhandari, TS Reddy, R Tokala, AP Sakla, ...
    European Journal of Medicinal Chemistry 200, 112457 , 2020
    2020
    Citations: 88
  • Ring-opening cyclization of activated spiro-aziridine oxindoles with heteroarenes: a facile synthetic approach to spiro-oxindole-fused pyrroloindolines
    S Bhandari, S Sana, V Lahoti, R Tokala, N Shankaraiah
    RSC advances 10 (27), 16101-16109 , 2020
    2020
    Citations: 14
  • Design and Synthesis of Substituted Dihydropyrimidinone Derivatives as Cytotoxic and Tubulin Polymerization Inhibitors
    S Sana, R Tokala, DM Bajaj, N Nagesh, KK Bokara, G Kiranmai, ...
    Bioorganic Chemistry, 103317 , 2019
    2019
    Citations: 57
  • Ru (II)-catalyzed regioselective hydroxymethylation of β-carbolines and isoquinolines via C–H functionalization: probing the mechanism by online ESI-MS/MS screening
    R Tokala, D Bora, S Sana, FM Nachtigall, LS Santos, N Shankaraiah
    The Journal of Organic Chemistry 84 (9), 5504-5513 , 2019
    2019
    Citations: 39
  • Microwave‐Assisted One‐Pot [3+ 2] Cycloaddition of Azomethine Ylides and 3‐Alkenyl Oxindoles: A Facile Approach to Pyrrolidine‐Fused Bis‐Spirooxindoles
    S Bhandari, S Sana, B Sridhar, N Shankaraiah
    ChemistrySelect 4 (5), 1727-1730 , 2019
    2019
    Citations: 34
  • Design and synthesis of DNA‐interactive β‐carboline–oxindole hybrids as cytotoxic and apoptosis‐inducing agents
    R Tokala, S Thatikonda, US Vanteddu, S Sana, C Godugu, ...
    ChemMedChem 13 (18), 1909-1922 , 2018
    2018
    Citations: 64
  • Synthesis and in vitro cytotoxicity evaluation of β-carboline-linked 2, 4-thiazolidinedione hybrids: potential DNA intercalation and apoptosis-inducing studies
    R Tokala, S Thatikonda, S Sana, P Regur, C Godugu, N Shankaraiah
    New Journal of Chemistry 42 (19), 16226-16236 , 2018
    2018
    Citations: 63

MOST CITED SCHOLAR PUBLICATIONS

  • Palladium catalyzed C–C and C–N bond forming reactions: an update on the synthesis of pharmaceuticals from 2015–2020
    J Rayadurgam, S Sana, M Sasikumar, Q Gu
    Organic Chemistry Frontiers 8 (2), 384-414 , 2021
    2021
    Citations: 222
  • Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect
    S Sana, VG Reddy, S Bhandari, TS Reddy, R Tokala, AP Sakla, ...
    European Journal of Medicinal Chemistry 200, 112457 , 2020
    2020
    Citations: 88
  • Cinnamide derived pyrimidine-benzimidazole hybrids as tubulin inhibitors: synthesis, in silico and cell growth inhibition studies
    S Sana, VG Reddy, TS Reddy, R Tokala, R Kumar, SK Bhargava, ...
    Bioorganic Chemistry 110, 104765 , 2021
    2021
    Citations: 76
  • Design and synthesis of DNA‐interactive β‐carboline–oxindole hybrids as cytotoxic and apoptosis‐inducing agents
    R Tokala, S Thatikonda, US Vanteddu, S Sana, C Godugu, ...
    ChemMedChem 13 (18), 1909-1922 , 2018
    2018
    Citations: 64
  • Synthesis and in vitro cytotoxicity evaluation of β-carboline-linked 2, 4-thiazolidinedione hybrids: potential DNA intercalation and apoptosis-inducing studies
    R Tokala, S Thatikonda, S Sana, P Regur, C Godugu, N Shankaraiah
    New Journal of Chemistry 42 (19), 16226-16236 , 2018
    2018
    Citations: 63
  • Design and Synthesis of Substituted Dihydropyrimidinone Derivatives as Cytotoxic and Tubulin Polymerization Inhibitors
    S Sana, R Tokala, DM Bajaj, N Nagesh, KK Bokara, G Kiranmai, ...
    Bioorganic Chemistry, 103317 , 2019
    2019
    Citations: 57
  • Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction
    R Tokala, S Mahajan, G Kiranmai, DK Sigalapalli, S Sana, SE John, ...
    Bioorganic Chemistry 106, 104481 , 2021
    2021
    Citations: 54
  • Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity
    R Tokala, S Sana, UJ Lakshmi, P Sankarana, DK Sigalapalli, N Gadewal, ...
    Bioorganic Chemistry 105, 104357 , 2020
    2020
    Citations: 43
  • Ru (II)-catalyzed regioselective hydroxymethylation of β-carbolines and isoquinolines via C–H functionalization: probing the mechanism by online ESI-MS/MS screening
    R Tokala, D Bora, S Sana, FM Nachtigall, LS Santos, N Shankaraiah
    The Journal of Organic Chemistry 84 (9), 5504-5513 , 2019
    2019
    Citations: 39
  • Microwave‐Assisted One‐Pot [3+ 2] Cycloaddition of Azomethine Ylides and 3‐Alkenyl Oxindoles: A Facile Approach to Pyrrolidine‐Fused Bis‐Spirooxindoles
    S Bhandari, S Sana, B Sridhar, N Shankaraiah
    ChemistrySelect 4 (5), 1727-1730 , 2019
    2019
    Citations: 34
  • Vanadium-Catalyzed Oxidative C (CO)–C (CO) Bond Cleavage for C–N Bond Formation: One-Pot Domino Transformation of 1, 2-Diketones and Amidines into Imides and Amides
    CS Digwal, U Yadav, PVS Ramya, S Sana, B Swain, A Kamal
    The Journal of Organic Chemistry 82 (14), 7332-7345 , 2017
    2017
    Citations: 32
  • Hexafluoroisopropanol as a bioconjugation medium of ultrafast, tryptophan-selective catalysis
    M Nuruzzaman, BM Colella, CP Uzoewulu, AE Meo, EJ Gross, S Ishizawa, ...
    Journal of the American Chemical Society 146 (10), 6773-6783 , 2024
    2024
    Citations: 28
  • Synthesis and biological evaluation of novel imidazo [1, 2-a] pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA …
    DK Sigalapalli, G Kiranmai, GP Devi, R Tokala, S Sana, C Tripura, ...
    Bioorganic & Medicinal Chemistry 43, 116277 , 2021
    2021
    Citations: 26
  • Synthesis and preclinical evaluation of indole triazole conjugates as microtubule targeting agents that are effective against MCF-7 breast cancer cell lines
    V Yele, SKSS Pindiprolu, S Sana, D Ramamurty, JRK Madasi, ...
    Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal … , 2021
    2021
    Citations: 21
  • Regioselective ortho ‐sulfonamidation: Exploration of Intrinsic Directing Property of β‐Carbolines and their Photophysical Studies
    D Bora, S Reddy Dannarm, S Elza John, S Sana, R Sonti, N Shankaraiah
    Asian Journal of Organic Chemistry 10 (12), 3384-3389 , 2021
    2021
    Citations: 17
  • Sustainable photocatalytic C–H annulation of heteroarenes with sulfoxonium ylides: synthesis and photophysical properties of fused imidazo [1, 2-a] pyridine-based molecules
    S Sana, SR Dannarm, R Tokala, S Dastari, M Sathish, R Kumar, R Sonti, ...
    Organic Chemistry Frontiers 10 (19), 4800-4808 , 2023
    2023
    Citations: 15
  • Ring-opening cyclization of activated spiro-aziridine oxindoles with heteroarenes: a facile synthetic approach to spiro-oxindole-fused pyrroloindolines
    S Bhandari, S Sana, V Lahoti, R Tokala, N Shankaraiah
    RSC advances 10 (27), 16101-16109 , 2020
    2020
    Citations: 14
  • Visible-light-mediated photocatalytic sequential N-arylation: an eco-friendly synthetic route to unsymmetrical diarylamines and the imatinib drug
    S Sana, S Dastari, DS Reddy, R Tokala, M Sathish, R Sonti, ...
    Organic Chemistry Frontiers 10 (18), 4573-4580 , 2023
    2023
    Citations: 7
  • Synthesis and Evaluation of Bispecific 64Cu—Radio conjugates for PET Imaging in Prostate Cancer Models
    S Sana, X Ma, W Zhao, S Cheng, X Wu, X Ni, Z Wu, Z Li
    Journal of Nuclear Medicine 66 (supplement 1), 252187-252187 , 2025
    2025
  • Synthesis and Evaluation of FAPI-Targeted 64Cu— Radioconjugates Containing Variable PEG Linkers for PET Imaging in U87 Cancer Models
    S Sana, X Ma, K Rakesh, W Zhao, Z Wu, Z Li
    Journal of Nuclear Medicine 65 (supplement 2), 242489-242489 , 2024
    2024