Pharmacology, Toxicology and Pharmaceutics, Pharmaceutical Science, Anatomy, Pharmacology
3
Scopus Publications
101
Scholar Citations
6
Scholar h-index
3
Scholar i10-index
Scopus Publications
Aromatherapy an integrative therapy of essential oils Sharada Nalla, Upendarrao Golla, Sujatha Palatheeya, Eswar Kumar Aouta Pharmacological Aspects of Essential Oils Current and Future Trends, 2023 Aromatherapy is a rapidly growing, alternative and integrative therapy that can replace the conventional medical treatment with essential oils for managing conditions like depression, anxiety, pain, nausea, vomiting, indigestion, joint pains, sleep disturbance, and muscle tension, and also to enhance physical and psychological wellbeing. The essential oils, which are derived from different plant parts like leaves, flowers, fruits, stems, roots, bark, grass etc., are used for the aromatherapy. Usually the oils are applied topically for massage or through inhalation. Olfactory stimulation of aromatherapy can result in immediate reduction in pain and other physiological parameters like blood pressure, pulse, skin temperature and activity of brain. Nowadays, aromatherapy is the most attractive therapy for treating illness and for enhancing wellbeing because of less side effects and low cost, so the use of essential oils for aromatherapy has increased in recent years. In the scientific literature, there is an increasing amount of evidence suggesting that there may be beneficial effects in treating a number of health conditions with plant essential oils, alone or in combination with other therapies. This review explores the latest information on literature of plants and their essential oils used in aromatherapy.
Tuning between Nuclear Organization and Functionality in Health and Disease Naresh Kumar Manda, Upendarrao Golla, Kishore Sesham, Parth Desai, Shrushti Joshi, Satyam Patel, Sharada Nalla, Susmitha Kondam, Lakhwinder Singh, Deepak Dewansh, Hemalatha Manda, Namita Rokana Cells, 2023 The organization of eukaryotic genome in the nucleus, a double-membraned organelle separated from the cytoplasm, is highly complex and dynamic. The functional architecture of the nucleus is confined by the layers of internal and cytoplasmic elements, including chromatin organization, nuclear envelope associated proteome and transport, nuclear–cytoskeletal contacts, and the mechano-regulatory signaling cascades. The size and morphology of the nucleus could impose a significant impact on nuclear mechanics, chromatin organization, gene expression, cell functionality and disease development. The maintenance of nuclear organization during genetic or physical perturbation is crucial for the viability and lifespan of the cell. Abnormal nuclear envelope morphologies, such as invagination and blebbing, have functional implications in several human disorders, including cancer, accelerated aging, thyroid disorders, and different types of neuro-muscular diseases. Despite the evident interplay between nuclear structure and nuclear function, our knowledge about the underlying molecular mechanisms for regulation of nuclear morphology and cell functionality during health and illness is rather poor. This review highlights the essential nuclear, cellular, and extracellular components that govern the organization of nuclei and functional consequences associated with nuclear morphometric aberrations. Finally, we discuss the recent developments with diagnostic and therapeutic implications targeting nuclear morphology in health and disease.
ABHD11‐AS1: An Emerging Long Non‐Coding RNA (lncRNA) with Clinical Significance in Human Malignancies Upendarrao Golla, Kishore Sesham, Siva Dallavalasa, Naresh Kumar Manda, Sambamoorthy Unnam, Arun Kumar Sanapala, Sharada Nalla, Susmitha Kondam, Rajesh Kumar Non Coding RNA, 2022 The aberrant expression of lncRNAs has been linked to the development and progression of different cancers. One such lncRNA is ABHD11 antisense RNA 1 (ABHD11-AS1), which has recently gained attention for its significant role in human malignancies. ABHD11-AS1 is highly expressed in gastric, lung, breast, colorectal, thyroid, pancreas, ovary, endometrium, cervix, and bladder cancers. Several reports highlighted the clinical significance of ABHD11-AS1 in prognosis, diagnosis, prediction of cancer progression stage, and treatment response. Significantly, the levels of ABHD11-AS1 in gastric juice had been exhibited as a clinical biomarker for the assessment of gastric cancer, while its serum levels have prognostic potential in thyroid cancers. The ABHD11-AS1 has been reported to exert oncogenic effects by sponging different microRNAs (miRNAs), altering signaling pathways such as PI3K/Akt, epigenetic mechanisms, and N6-methyladenosine (m6A) RNA modification. In contrast, the mouse homolog of AHD11-AS1 (Abhd11os) overexpression had exhibited neuroprotective effects against mutant huntingtin-induced toxicity. Considering the emerging research reports, the authors attempted in this first review on ABHD11-AS1 to summarize and highlight its oncogenic potential and clinical significance in different human cancers. Lastly, we underlined the necessity for future mechanistic studies to unravel the role of ABHD11-AS1 in tumor development, prognosis, progression, and targeted therapeutic approaches.
RECENT SCHOLAR PUBLICATIONS
Evaluation of in-vitro aldose reductase and anti-diabetic activities of Murraya koenigii seeds. S Nalla, D Sujatha, U Golla 2023
Aromatherapy: An integrative therapy of essential oils S Nalla, U Golla, S Palatheeya, EK Aouta Pharmacological Aspects of Essential Oils, 120-125 , 2023 2023 Citations: 6
Tuning between nuclear organization and functionality in health and disease NK Manda, U Golla, K Sesham, P Desai, S Joshi, S Patel, S Nalla, ... Cells 12 (5), 706 , 2023 2023 Citations: 18
Tuning between Nuclear Organization and Functionality in Health and Disease. Cells 2023, 12, 706 NK Manda, U Golla, K Sesham, P Desai, S Joshi, S Patel, S Nalla, ... 2023
ABHD11-AS1: an emerging long non-coding RNA (lncRNA) with clinical significance in human malignancies U Golla, K Sesham, S Dallavalasa, NK Manda, S Unnam, AK Sanapala, ... Non-coding RNA 8 (2), 21 , 2022 2022 Citations: 25
Perspectives on the global impact and effectiveness of covid-19 vaccines against emerging SARS Cov-2 variant omicron sharada nalla, uppendar golla Advances in clinical toxicology 7 (1) , 2022 2022
In Vitro Aldose Reductase Inhibition and Antidiabetic Activity of White Pepper in Streptozotocin (STZ) Induced Diabetic Rats S Nallaa, D Sujathab, U Gollac NeuroQuantology 20 (19), 1989 , 2022 2022
A review on pharmacognosy, phytochemistry and therapeutic importance of Murraya koenigii, azadirachta indica and Piper nigrum S Nalla, S Dodoala, U Golla Journal of Integral Sciences, 1-8 , 2020 2020 Citations: 2
A review on novel approach to pharmaceutical drug delivery: 3D printing NS A Eswar kumar, G. chinnadevi International journal of pharmaceutical sciences and research 10 (4), 1575-1581 , 2019 2019 Citations: 5
An update on medicinal plants for Alzheimer’s disease : a review NS A Eswar kumar World journal of pharmacy and pharmaceutical sciences 7 (1), 325-333 , 2018 2018
FORMULATION DEVELOPMENT AND INVITRO EVALUATION OF AZATHIOPRINE TABLETS FOR COLON DRUG DELIVERY SYSTEM” E Kumar, S Nalla, B Thirupathaiah 2016
Review on Non-Communicable Diseases b. shyamala n.sharada, b.swathi, g.venkateswarlu, k.sushmitha, k.swapnareddy ... World journal of Pharmaceutical Sciences. 3 (4), 754-757 , 2015 2015
Changes of life style prevent heart stroke, kidney failure, paralysis S Swathi, B Swathi, K Swapna, G Venkateshwarlu, N Sharada, SP Laxmi Asian Journal of Pharmaceutical Research 5 (1), 48-50 , 2015 2015 Citations: 3
Ashwgandha- An important medicinal plant: A review on its folklore and traditional uses k. swapnareddy b swathi, goli.venkateswarlu, n.sharada, ragya eslavath ... Journal of chemical, biological and physical sciences 5 (1), 529-531 , 2014 2014
A new analytical method development and validation for estimation of Ciprofloxacin in bulk and pharmaceutical dosage form M Sabat, S Nalla, V Goli, SP Macherla, PK Matta Asian Journal of Pharmaceutical Analysis 2 (4), 116-117 , 2012 2012 Citations: 22
Analytical Method Development and Validation of Lamivudin by Using Revers Phase HPLC S Manoranjan, N Sharada, G Venkateswarlu, SM Prasad, MD Noorunnisa, ... Journal of Chemical, Biological and Physical Sciences (JCBPS) 2 (4), 1816 , 2012 2012
Salubrious Effect of Ethanolic Extract of Cassia auriculata Linn., in Streptazotocin-Nicotinamide induced Diabetes in Rat Model S Nalla, V Goli, M Sabat, S Komati, N Begam, VR Kokkirala Asian Journal of Pharmacy and Technology 2 (3), 104-106 , 2012 2012 Citations: 5
Salubrious effect of ethanolic extract of Cassia auriculata Linn., in streptazotocin-nicotinamide induced diabetes in rat model. SN Sharada Nalla, VG Venkateswarlu Goli, MS Manoranjan Sabat, ... 2012 Citations: 6
Comparision of anti-larvacidal activity of Cassia occidentalis , Bamboosa vulgaris and Sapindus mukurossi . G Venkateswarlu, S Manoranjan, N Sharada, MS Prasad, MD Azeez, ... 2012 Citations: 7
Antidiabetic activity of ethanolic extract of Nymphea lotus roots on streptazotocin induced diabetic rats. G Sowmya, SR Solomon, SN Sharada Nalla, NL Reddy, ... 2012
MOST CITED SCHOLAR PUBLICATIONS
ABHD11-AS1: an emerging long non-coding RNA (lncRNA) with clinical significance in human malignancies U Golla, K Sesham, S Dallavalasa, NK Manda, S Unnam, AK Sanapala, ... Non-coding RNA 8 (2), 21 , 2022 2022.0 Citations: 25
A new analytical method development and validation for estimation of Ciprofloxacin in bulk and pharmaceutical dosage form M Sabat, S Nalla, V Goli, SP Macherla, PK Matta Asian Journal of Pharmaceutical Analysis 2 (4), 116-117 , 2012 2012.0 Citations: 22
Tuning between nuclear organization and functionality in health and disease NK Manda, U Golla, K Sesham, P Desai, S Joshi, S Patel, S Nalla, ... Cells 12 (5), 706 , 2023 2023.0 Citations: 18
Comparision of anti-larvacidal activity of Cassia occidentalis , Bamboosa vulgaris and Sapindus mukurossi . G Venkateswarlu, S Manoranjan, N Sharada, MS Prasad, MD Azeez, ... 2012.0 Citations: 7
Aromatherapy: An integrative therapy of essential oils S Nalla, U Golla, S Palatheeya, EK Aouta Pharmacological Aspects of Essential Oils, 120-125 , 2023 2023.0 Citations: 6
Salubrious effect of ethanolic extract of Cassia auriculata Linn., in streptazotocin-nicotinamide induced diabetes in rat model. SN Sharada Nalla, VG Venkateswarlu Goli, MS Manoranjan Sabat, ... 2012.0 Citations: 6
A review on novel approach to pharmaceutical drug delivery: 3D printing NS A Eswar kumar, G. chinnadevi International journal of pharmaceutical sciences and research 10 (4), 1575-1581 , 2019 2019.0 Citations: 5
Salubrious Effect of Ethanolic Extract of Cassia auriculata Linn., in Streptazotocin-Nicotinamide induced Diabetes in Rat Model S Nalla, V Goli, M Sabat, S Komati, N Begam, VR Kokkirala Asian Journal of Pharmacy and Technology 2 (3), 104-106 , 2012 2012.0 Citations: 5
Changes of life style prevent heart stroke, kidney failure, paralysis S Swathi, B Swathi, K Swapna, G Venkateshwarlu, N Sharada, SP Laxmi Asian Journal of Pharmaceutical Research 5 (1), 48-50 , 2015 2015.0 Citations: 3
A review on pharmacognosy, phytochemistry and therapeutic importance of Murraya koenigii, azadirachta indica and Piper nigrum S Nalla, S Dodoala, U Golla Journal of Integral Sciences, 1-8 , 2020 2020.0 Citations: 2
State P, Medical H, Sunder S, Bhimathati R (2014) In SILICO design and ADMET prediction of rivastigmine analogues for treatment of Alzheimer’s disease UR Golla An Int J Adv Pharm Sci 4, 270-278 , 0 Citations: 2
Evaluation of in-vitro aldose reductase and anti-diabetic activities of Murraya koenigii seeds. S Nalla, D Sujatha, U Golla 2023.0
Tuning between Nuclear Organization and Functionality in Health and Disease. Cells 2023, 12, 706 NK Manda, U Golla, K Sesham, P Desai, S Joshi, S Patel, S Nalla, ... 2023.0
Perspectives on the global impact and effectiveness of covid-19 vaccines against emerging SARS Cov-2 variant omicron sharada nalla, uppendar golla Advances in clinical toxicology 7 (1) , 2022 2022.0
In Vitro Aldose Reductase Inhibition and Antidiabetic Activity of White Pepper in Streptozotocin (STZ) Induced Diabetic Rats S Nallaa, D Sujathab, U Gollac NeuroQuantology 20 (19), 1989 , 2022 2022.0
An update on medicinal plants for Alzheimer’s disease : a review NS A Eswar kumar World journal of pharmacy and pharmaceutical sciences 7 (1), 325-333 , 2018 2018.0
FORMULATION DEVELOPMENT AND INVITRO EVALUATION OF AZATHIOPRINE TABLETS FOR COLON DRUG DELIVERY SYSTEM” E Kumar, S Nalla, B Thirupathaiah 2016.0
Review on Non-Communicable Diseases b. shyamala n.sharada, b.swathi, g.venkateswarlu, k.sushmitha, k.swapnareddy ... World journal of Pharmaceutical Sciences. 3 (4), 754-757 , 2015 2015.0
Ashwgandha- An important medicinal plant: A review on its folklore and traditional uses k. swapnareddy b swathi, goli.venkateswarlu, n.sharada, ragya eslavath ... Journal of chemical, biological and physical sciences 5 (1), 529-531 , 2014 2014.0
Analytical Method Development and Validation of Lamivudin by Using Revers Phase HPLC S Manoranjan, N Sharada, G Venkateswarlu, SM Prasad, MD Noorunnisa, ... Journal of Chemical, Biological and Physical Sciences (JCBPS) 2 (4), 1816 , 2012 2012.0