Analyzing the Relationship of Inferior Nerve Canal to Impacted Mandibular Third Molars Using Cone-beam Computed Tomography Narendra V Penumatsa, Shazia Mushtaq, Fazil A Nasyam, Jugajyoti Pathi, Rajat Mohanty, Akshata Rao, Ranjini K Vijayarangan World Journal of Dentistry, 2025 An impacted tooth is a tooth that fails to erupt into the dental arch within the expected developmental window and remains embedded in the jawbone or soft tissue beyond its normal eruption time. 1 Impacted teeth are very common in the general population with an overall prevalence of around 36.9% with highest prevalence recorded in Asia-43.1% and lowest in Europe-24.5% based on a meta-analysis conducted till December 2023, and a male-to-female predilection of 1.5:1, based on a survey conducted in New Delhi between 2024 and 2016.Impacted teeth possess various risks which include 15% of dental caries, 34.1% of pericoronitis, 11% of dentigerous cyst, and up to 5.7% of ameloblastoma.Hence, a treatment modality of extraction is usually indicated. [2][3]][4][5][6] The position of inferior alveolar canal which includes the inferior alveolar nerve (IAN) and vessels is often a reason of concern during treatment due to its close proximity to the roots of the impacted third molar with around 59.86% directly beneath the roots of impacted third molars, around 30% in direct contact with mandibular canal, and 22.3% buccally and 19% lingually placed with respect to the third molars. 7A general risk of around 0.35-8.4% of third molar extraction is associated with nerve damage, with an increased risk of up to 30% when the teeth are in close contact. 8Thus a diagnostic evaluation 1,
Evaluation of the Effectiveness of Different Dental Varnishes on White Spot Lesion around Orthodontic Brackets: A Scanning Electron Microscope Study Diya Chakraborty, Mora SR Reddy, George Sam, Angel Kurian, Mayank Trivedi, Ambikathanaya U Kumaraswamy, Shazia Mushtaq Journal of Contemporary Dental Practice, 2025 Aim:The current study was aimed to evaluate the impact of three different dental varnishes on white spot lesions (WSLs) underlying orthodontic brackets. Materials and methods:The present study sample consisted of 90 premolar teeth that were extracted for orthodontic reasons.Following the placement of the brackets, each sample was coated with nail polish, preserving a 3 mm long 3 mm wide window from the bracket margin's cervical region.The demineralizing process was carried out using a demineralizing solution, and a scanning electron microscope (SEM) was used to collect the baseline data.Simple randomized sampling was used to randomly divide all 90 extracted teeth into three groups, i.e., 30 samples in each group.Group I: Fluor Protector varnish, group II: Clinpro White varnish, group III: CPP-ACPF Varnish.After a week, a layer of varnish solution was directly applied to the tooth surface using a microbrush.The effectiveness of each sample was assessed after 15 days using an SEM set at 2000 magnification.Data was recorded and statistically analyzed.Results: At baseline, the enamel demineralization score was 134.28 0.16 Fluor Protector varnish group, 135.18 0.06 for Clinpro White varnish group, and 134.02 0.30 for the CPP-ACPF varnish group.No significant difference was obtained among the three different enamel demineralization scores.After 2 weeks, the maximum reduction of scores was found in the CPP-ACPF varnish group, i.e., 98.68 0.10, followed by the Clinpro White varnish group with a mean score of 108.32 0.02 and the Fluor Protector varnish group with a mean score of 114.46 0.09.A significant difference was obtained among three different enamel demineralization scores. Conclusion:On conclusion, employing CPP-ACPF varnish around the orthodontic bracket could efficiently prevent the formation of WSL and provide surface enamel protection as compared to the Clinpro White varnish group and Fluor Protector varnish group.Clinical significance: White spot lesion formation or enamel demineralization throughout the course of fixed appliance therapy is one of the most frequent clinical challenges in orthodontic clinical practice.Therefore, these lesions present esthetic difficulties, which influence the patient's perception of treatment satisfaction.Applying fluoride varnish can considerably reduce the demineralization lesion that forms around the bracket after fluorapatite is formed.
Evaluation of Dermatoglyphic Patterns between Two Different Ethnic Populations: A Comparative Study George Sam, Arpita Singh, Shazia Mushtaq, Biswaroop Mohanty, Nivedita Sahoo, Shilpa Mailankote, Saiid Elshafey M Beshir, Nilanjana Sarkar World Journal of Dentistry, 2024 IntroductIonOver the past 100 years, reliable methods of human identification have been based on finger and palm prints.The study of the patterns created by dermal ridges on the palms, soles, and fingers is known as dermatoglyphics, a term that was first used by Cummins. 1 During the 3rd month of intrauterine life (IUL), dermal ridges start to form and fully develop by the 6th month.The dermal configurations remain the same till adulthood except forth change in size.In dermatoglyphics, analysis is done using the impression of the fingertips' papillary ridges.The palms, soles, and flexure surfaces of the fingers are where papillary ridges are primarily seen.With the opening of sweat ducts at the peak of each ridge, they form fine parallel or coiled arrays separated by a thin furrow.2][3] The impressions left by the fingers, palms, and soles are thought to result from both inheritance and environment.Nobody has the same fingerprints twice, not even monozygotic twins.Hence, each person's fingerprints are distinct and do not change over time.Medical dermatoglyphics is currently linked to a number of illnesses, including diabetes mellitus, hypertension, psychosis, 4,5 breast cancer, 6 alcohol embryopathy, 7 epilepsy, 8 and congenital cardiac disorders. 9Previous research indicates that individuals with periodontitis, 10 dental caries, 11 and birth defects such cleft lip and palate might have asymmetrical fingerprints. 12,13
Revitalizing oral cancer research: Crispr-Cas9 technology the promise of genetic editing Sowmya S. V., Dominic Augustine, Shazia Mushtaq, Hosam Ali Baeshen, Heba Ashi, Reem Nabil Hassan, Mohammed Alshahrani, Shankargouda Patil Frontiers in Oncology, 2024 This review presents an in-depth analysis of the immense potential of CRISPR-Cas9 technology in revolutionizing oral cancer research. It underscores the inherent limitations of conventional treatments while emphasizing the pressing need for groundbreaking approaches. The unparalleled capability of CRISPR-Cas9 to precisely target and modify specific genes involved in cancer progression heralds a new era in therapeutic intervention. Employing genome-wide CRISPR screens, vulnerabilities in oral cancer cells can be identified, thereby unravelling promising targets for therapeutic interventions. In the realm of oral cancer, the disruptive power of CRISPR-Cas9 manifests through its capacity to perturb genes that are intricately associated with drug resistance, consequently augmenting the efficacy of chemotherapy. To address the challenges that arise, this review diligently examines pertinent issues such as off-target effects, efficient delivery mechanisms, and the ethical considerations surrounding germline editing. Through precise gene editing, facilitated by CRISPR/Cas9, it becomes possible to overcome drug resistance by rectifying mutations, thereby enhancing the efficacy of personalized treatment strategies. This review delves into the prospects of CRISPR-Cas9, illuminating its potential applications in the domains of medicine, agriculture, and biotechnology. It is paramount to emphasize the necessity of ongoing research endeavors and the imperative to develop targeted therapies tailored specifically for oral cancer. By embracing this comprehensive overview, we can pave the way for ground-breaking treatments that instill renewed hope for enhanced outcomes in individuals afflicted by oral cancer.
Evaluation of Fibrin Clot Interaction with Dental Implant after Different Surface Treatments: An In Vitro Study Shazia Mushtaq, Subhash Sonkesriya, Pavithra K Ramanna, Mohammad Jalaluddin, Deesha Kumari, Monalisa Swain, Priyanka Rana, Dina A A Derbala, Linda F Mirza, Saiid E M Beshir Journal of Contemporary Dental Practice, 2024 AIM: The current study was carried out to assess the interaction between fibrin clots and dental implants following various surface treatments. MATERIALS AND METHODS: -values less than 0.05 were regarded as statistically significant. RESULTS: < 0.001). CONCLUSION: All surface-treatment methods exhibit adhesion between the implant surface and the fibrin clot. However, the highest adherence of fibrin clot was found in SLA treated group compared to the UV light-treated and control group. CLINICAL SIGNIFICANCE: Study. J Contemp Dent Pract 2024;25(3):276-279.
Prevalence of electronic cigarette usage among medical students in Saudi Arabia - A systematic review S Patil, HN Fageeh, S Mushtaq, M Ajmal, SN Chalikkandy, H Ashi, ZH Ahmad, SS Khan, S Khanagar, S Varadarajan, SC Sarode, GS Sarode Nigerian Journal of Clinical Practice, 2022 The systematic review aimed to report the prevalence of electronic cigarette (e-cigarette) usage among medical students in Saudi Arabia. Electronic databases were searched for scientific research articles published from January 2010 until December 2020. The data search was performed in electronic search engines such as PubMed, Google Scholar, Scopus, Web of Science, Medline, Embase, Cochrane, and Saudi Digital Library. A total of five research articles that qualified the eligibility criteria were analyzed for qualitative data. The sample size in the included studies ranged from 229 to 1007 participants. The prevalence of e-cigarette usage ranged from 10.6% to 27.7% among medical students in Saudi Arabia. Studies have also reported that the prevalence of e-cigarette usage is higher among the male population in comparison with the female population. The prevalence of e-cigarette usage among medical students in Saudi Arabia is high. Similar to tobacco smoking, e-cigarette usage is a major public health issue and concern among the younger population because they have potential benefits in some and are harmful to some and also it is still unclear whether they are effective for quitting smoking. Regulatory bodies must focus and initiate strict laws and policies to minimize the sales of these products to the younger population. Health promotion strategies need to be developed to reduce the usage of e-cigarettes.
Subepithelial Hyalinisation Predicts Recurrence of Unicystic Ameloblastomas Dominic Augustine, Roopa S. Rao, Lakshminarayana Surendra, Bharti Gupta, Thuckanaickenpalayam Ragunathan Yoithapprabhunath, Pradeep Kumar Yadalam, Shazia Mushtaq, Zeeshan Hera Ahmed, Shankargouda Patil Diagnostics, 2022 The inductive effect of hyalinisation and its influence on the biologic behaviour of ameloblastoma variants represent a scarcely researched domain of oral pathology. The complexity of the induction effects within the odontogenic apparatus, with the involvement of both ectodermal and mesodermal tissues, is responsible for diverse histopathological characteristics, hyalinisation being the major feature. The present study aims to deduce for the first time the correlation between the severity of hyalinisation (SOH) and recurrence in three unicystic ameloblastoma (UA) variants, namely, intra-luminal (UA-IL), luminal (UA-L) and mural (UA-M). Retrospectively diagnosed archival cases of UA-IL (n = 08), UA-L (n = 22) and UA-M (n = 30) were assessed for SOH and its correlation with recurrence. A subgroup comparison (between UA-IL/UA-L and UA-M) was also performed. The clinical parameters of the patients were also analysed from files for clinicopathological correlation with recurrence. Results: sub-epithelial hyalinisation (SEH) significantly correlated with the recurrence of UA-L and UA-M (p = 0.001). When the histologic types (UA-L and UA-IL vs. UA-M) were grouped and the correlation of SOH with recurrence was checked, it was observed that both groups (p = 0.001) showed strong statistical correlation. UA-M lesions with multilocular radiolucency (p = 0.001) also showed significant correlation with recurrence. SOH can be a reliable histological predictor of recurrence and of aggressive biologic behaviour in UA. The present study shows a significant association of hyalinisation with the biologic behaviour of UA. Further studies with immunohistochemical investigations could validate the presence of hyalinisation and identify the origin of the hyalinised product in UAs.
Polysaccharide-Drug Conjugates: A Tool for Enhanced Cancer Therapy Neena Yadav, Arul Prakash Francis, Veeraraghavan Vishnu Priya, Shankargouda Patil, Shazia Mustaq, Sameer Saeed Khan, Khalid J. Alzahrani, Hamsa Jameel Banjer, Surapaneni Krishna Mohan, Ullas Mony, Rukkumani Rajagopalan Polymers, 2022
