Sunandha Jeeva Bharathi G

@alagappauniversity.ac.in

Research Scholar and Department of Microbiology/Faculty of Science
Alagappa University

RESEARCH INTERESTS

Virology, Molecular Biology, Immunology, Marine Microbiology, Antimicrobial Peptides investigation, Microbial Biofilm
3

Scopus Publications

42

Scholar Citations

4

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Outbreak investigation of fever mimicking dengue in Havelock Island, an important tourist destination in the Andaman & Nicobar Archipelago, 2014
    C. KARTICK, G. S. J. BHARATHI, P. SURYA, M. ANWESH, S. ARUN, N. MURUGANANDAM, R. AVIJIT, P. VIJAYACHARI
    Epidemiology and Infection, 2017
    SUMMARYAn upsurge of fever cases of unknown origin, but resembling dengue and leptospirosis was reported in Havelock, Andaman & Nicobar Islands, an important tourism spot, during May 2014. Investigations were carried out to determine the aetiology, and to describe the epidemiology of the outbreak. The data on fever cases attending Primary Health Centre (PHC), Havelock showed that the average number of cases reporting per week over the last 2 years was 46·1 (95% confidence interval 19·4–72·9). A total of 27 (43·5%) patients out of the 62 suspected cases were diagnosed as having DENV infection based on a positive enzyme immunoassay or reverse transcriptase–polymerase chain reaction. The overall attack rate was 9·4 cases/1000 population and it ranged between 2·8 and 18·8/1000 in different villages. The nucleotide sequencing showed that the virus responsible was DENV-3. DENV-3 was first detected in the Andaman & Nicobar Islands in 2013 among wharf workers in Port Blair and within a year it has spread to Havelock Island which is separated from South Andaman by 36 nautical miles.
  • Emergence of infl uenza A (H1N1) PDM09 in the remote Islands of India - A molecular approach
    N Muruganandam, D Bhattacharya, IK Chaaithanya, H Bhattacharya, R Reesu, A Maile, GSJ Bharathi, AP Sugunan, P Vijayachari
    Indian Journal of Medical Microbiology, 2015
    Background: A disease outbreak of A (H1N1) PDM09 was reported in Andaman and Nicobar islands in 2009 with an attack rate of 33.5% among settler population and 26.3% among the aboriginal Nicobarese tribe. During the ongoing outbreak of A (H1N1) PDM09 disease in different parts of the world, a subject working in Dubai city of Saudi Arabia, came to Port Blair, following which the pandemic triggered for the first time in these Islands. Materials and Methods: During the period August 2009 to January 2011, 30 confirmed cases of Influenza A (H1N1) PDM09 virus infection was detected. To understand the genetic relationship, the NA gene sequences of the viruses were phylogenetically analysed together along with the virus sequence isolated from other parts of the world. Result: Formation of multiple clusters were observed, with the sequences of Andaman Islands, mainland India, Mexico, Saudi Arabia and few other counties clustering together. The sequence analysis data revealed that there was no specific mutation conferring resistance to oseltamivir among the Andaman A (H1N1) PDM09 virus isolates. The result of phylogenetic analysis have also revealed that the A (H1N1) PDM09 virus might have spread in these remote Islands of India via the subject from Saudi Arabia/Dubai. Conclusion: A (H1N1) PDM09 Influenza outbreak have highlighted the need to strengthen the region-specific pandemic preparedness plans and surveillance strategies.
  • Isolation and molecular characterization of chikungunya virus from the Andaman and Nicobar archipelago, India: Evidence of an East, central, and South African genotype
    N. Muruganandam, I.K. Chaaithanya, G.S. Senthil, A.N. Shriram, D. Bhattacharya, G.S. JeevaBharathi, A.B. Sudeep, N. PradeepKumar, P. Vijayachari
    Canadian Journal of Microbiology, 2011
    Chikungunya virus (CHIKV) is an Alphavirus belonging to the family Togaviridae. In 2006, CHIKV infection struck the Andaman and Nicobar archipelago, with an attack rate of 60%. There were more than 10 cases with acute flaccid paralysis simulating the Guillian Barre Syndrome. The majority of the patients presented severe joint pain. The cause for such an explosive nature of the outbreak with increased morbidity was not known. The isolation of CHIKV was attempted and succeeded from nine subjects presenting clinical symptoms of Chikungunya fever. The cDNA of all the isolates was sequenced for partial E1 and nsP1 genes. Sequences were aligned based on the double locus sequence typing concept. The phylogenetic analysis shows that sequences of Andaman isolates grouped with the East, Central, and South African genotype of virus isolates from India, Sri Lanka, and Réunion. The genetic distance between Andaman isolates and the Réunion isolates was very small. The phylogenetic analysis confirmed the origin of the isolates responsible for the first ever confirmed CHIKV outbreak in these islands to be the East, Central, and South African genotype. In this manuscript, we discuss the involvement of the East, Central, and South African strain with the Chikungunya fever outbreak in this archipelago and double locus sequence typing as a first time approach.

RECENT SCHOLAR PUBLICATIONS

  • Production and characterization of exopolysaccharide (EPS) from marine Bacillus halotolerans and its antibacterial activity against clinical pathogens
    A Ravindran, AC Manivannan, GSJ Bharathi, V Balasubramanian, ...
    Biologia 79 (2), 605-619 , 2024
    2024.0
    Citations: 10
  • Algae materials for textile industries
    I Ayyanar, A Ravindran, R Rajendran, A Arulprakasam, B Vellaisamy
    Algae Materials, 231-246 , 2023
    2023.0
    Citations: 7
  • Antiviral biomolecules from marine inhabitants
    I Ayyanar, SS Krishnan, A Ravindran, SJB Gunasekaran, B Vellaisamy
    Viral Infections and Antiviral Therapies, 537-566 , 2023
    2023.0
    Citations: 1
  • Outbreak investigation of fever mimicking dengue in Havelock Island, an important tourist destination in the Andaman & Nicobar Archipelago, 2014
    C Kartick, GSJ Bharathi, P Surya, M Anwesh, S Arun, N Muruganandam, ...
    Epidemiology & Infection 145 (7), 1437-1442 , 2017
    2017.0
    Citations: 12
  • Emergence of influenza A (H1N1) PDM09 in the remote Islands of India–A molecular approach
    N Muruganandam, D Bhattacharya, IK Chaaithanya, H Bhattacharya, ...
    Indian Journal of Medical Microbiology 33 (1), 143-146 , 2015
    2015.0
    Citations: 3
  • Isolation and molecular characterization of Chikungunya virus from the Andaman and Nicobar archipelago, India: evidence of an East, Central, and South African …
    N Muruganandam, IK Chaaithanya, GS Senthil, AN Shriram, ...
    Canadian journal of microbiology 57 (12), 1073-1077 , 2011
    2011.0
    Citations: 8
  • Research on reemerging of chikungunya-virus disease
    SG Sundarama, M Vijayalakshmia, IK Chaaitanyab, M Nagarajanb, ...
    J. Chem Pharm Res 2, 766-773 , 2010
    2010.0
    Citations: 1
  • Integrating In Silico and In Vitro Studies to develop phytobiotic therapeutics for Aeromonas hydrophila in Aquaculture
    NMDA Vishali Krishnan1, Jamal Mohamed, Sunandha Jeeva Bharathi G, Esther ...
    International Journal of Drug Delivery Technology 16 (Issue 4s) , 0

MOST CITED SCHOLAR PUBLICATIONS

  • Outbreak investigation of fever mimicking dengue in Havelock Island, an important tourist destination in the Andaman & Nicobar Archipelago, 2014
    C Kartick, GSJ Bharathi, P Surya, M Anwesh, S Arun, N Muruganandam, ...
    Epidemiology & Infection 145 (7), 1437-1442 , 2017
    2017.0
    Citations: 12
  • Production and characterization of exopolysaccharide (EPS) from marine Bacillus halotolerans and its antibacterial activity against clinical pathogens
    A Ravindran, AC Manivannan, GSJ Bharathi, V Balasubramanian, ...
    Biologia 79 (2), 605-619 , 2024
    2024.0
    Citations: 10
  • Isolation and molecular characterization of Chikungunya virus from the Andaman and Nicobar archipelago, India: evidence of an East, Central, and South African …
    N Muruganandam, IK Chaaithanya, GS Senthil, AN Shriram, ...
    Canadian journal of microbiology 57 (12), 1073-1077 , 2011
    2011.0
    Citations: 8
  • Algae materials for textile industries
    I Ayyanar, A Ravindran, R Rajendran, A Arulprakasam, B Vellaisamy
    Algae Materials, 231-246 , 2023
    2023.0
    Citations: 7
  • Emergence of influenza A (H1N1) PDM09 in the remote Islands of India–A molecular approach
    N Muruganandam, D Bhattacharya, IK Chaaithanya, H Bhattacharya, ...
    Indian Journal of Medical Microbiology 33 (1), 143-146 , 2015
    2015.0
    Citations: 3
  • Antiviral biomolecules from marine inhabitants
    I Ayyanar, SS Krishnan, A Ravindran, SJB Gunasekaran, B Vellaisamy
    Viral Infections and Antiviral Therapies, 537-566 , 2023
    2023.0
    Citations: 1
  • Research on reemerging of chikungunya-virus disease
    SG Sundarama, M Vijayalakshmia, IK Chaaitanyab, M Nagarajanb, ...
    J. Chem Pharm Res 2, 766-773 , 2010
    2010.0
    Citations: 1
  • Integrating In Silico and In Vitro Studies to develop phytobiotic therapeutics for Aeromonas hydrophila in Aquaculture
    NMDA Vishali Krishnan1, Jamal Mohamed, Sunandha Jeeva Bharathi G, Esther ...
    International Journal of Drug Delivery Technology 16 (Issue 4s) , 0